my choice for best acid has unfortunately been schedule 1 since 1970. but really though. sulfuric acid is like, the grandfather of modern chemistry. i’d very readily call it “the best acid” because it’s just so tried and true. also it makes piranha solution, which is my candidate for “scariest colorless liquid”.
1970 was a really bad year for humanity, when some bafoons said "hey, your body is not your own" and just claimed humanity as its own to do what it will with. Because, if you don't own it, someone else does. Always.
@fictionindianspaceprogram-222 Ron Paul (Rand Paul’s father) was a Republican, then he turned into a libertarian and started advocating for ending the war on drugs. Timothy Leary even set up a donation event for his Presidential campaign. It’s dangerous to make generalizations like that because I don’t see many Democrats advocating for ending the War on Drugs.
Citric acid and ascorbic acid are the two I most often use in tankless water heater descaling, and as such I have a misplaced love for them. We used to use good old acetic acid, but few years ago a certain Japanese manufacturer's rep had us change to a less offensive smelling solution after going through comparison tests in the car park of the local hardware store. Got paid for a full day of watching someone else do my job 4-5 times in a row, and learned quite a bit in the process! All because a local plumber hated the smell of vinegar :)
John D. Clark's book Ignition! describes an interesting use of HF: In the late 1940s-early 1950s a very popular rocket propellant combination was a hydrazine and fuming nitric acid. This of course had two problems: hydrazine actively seeks out ways to kill you, and nitric acid will dissolve a flyable oxidizer tank no matter what you make it out of. You could PROBABLY make one out of fiberglass, but that would be heavy. Since the intent of using propellants that are liquid at room temperature is to be able to fill a rocket with propellant and wait until you want to fire it - maybe years, if the rocket has a warhead on it and there's no war at the present time. In 1951, a new hire at Dr. Clark's lab came up with the weird idea that a fluoride coating on the inside of the tank would protect it from the nitric acid. They tried it and discovered it works well until the nitric acid dissolves the fluoride coating. His next bright idea was to make the coating self-healing by putting HF in the nitric acid...which actually worked. Now they call it "inhibited nitric acid." Putting one very corrosive acid into another very corrosive acid to make the mixture less corrosive. Whoda thunk?
Picric acid used to be a reagent in old labs. It used to be that reagent you looked for when buying an old lab, so you could get rid of it before it blew the door off its cabinet.
HF is actually useful when it comes to Silicon wafer processing. I've actually used it for dipping my silicon wafer in HF for only 10 seconds in my 2nd year at my Local Community College. My professor told us in very serious tone of not to get in on out skin or clothing (we are in a class 10000 cleanroom even though it's not the correct condition to be doing wafer processing, it was only for demonstration) and if we were to get on our skin, we need to get calcium gluconate (C12 H22 Ca O14) on the area where the HF landed on. From what my professor also said that you're not going to feel the acid on you but it will eat away as you mentioned. Btw if your wondering, I've never got any on me so I'm fine
I can't help but wonder if we go to the same community college. I don't want to say the name of the college, but is the cleanroom at the far end of the third floor in a long skinny building?
"If I was mean to benzoic acid, you guys would never let me hear the end of it, so I'm gonna put it in A tier just to suppress the hatred in the comments." Guys, it's working. We're bullying him just enough. (great work as always m8 even if i haven't finished the video yet)
When one of the off-site higher ups found out we use perchloric acid in our analytical laboratory, where it is mixed with isopropanol to dissolve 4-dimethylbenzaldhyde. There were a few frantic phone calls to our lab manager, questions about the fumehood we use it in, though not the method if I recall, followed by a stop work order being issued. Not long after we were able to calm things down when we showed that we only use 70% HClO4, not the anhydrous stuff that likes to combust/explode on contact with organics.
If you do furniture refinishing, oxalic acid is useful for bleaching black stains caused by water penetrating the finish and soaking into the wood below. This often happens when someone overwaters a potted plant which is sitting on an end table.
one I'd add is carborane acids, which are stronger still than fluorantimonic acid - they can protonate benzene! - yet they're crystalline solids that are easy to store and handle the complicated process of synthesis makes them impractical for large-scale use, but they do have a pretty cool shape (icosahedron)
Person who actually enjoys working with HF here! In my last job, it was a daily to use it to homogenize up recycled fuel-samples - of course it was just a part of the whole ICP process, but I actually grew fond of it! The only minus I found, was doing the complexing after the actual melt, that was a pain in the ass because of all the vapors.
HClO4 at least C tier...its one of the reagents we have a heart for. You can crystalize out potassium with it when the solution is cooled. High tier because of the roumers and the interesting salts. Love your content
My school chemistry was a nightmare. Almost only acids and bases for two years straight, which was only alkaline metals and sometimes hydrochloric acid. And phenolphthalein. Again and again. Our teacher was talking painstakingly slowly and was more worried about our handwriting than showing us something new. I would loved to have anything slightly complex, but the only other experiments I can remember were like heating iron with sulfur or his diy thermite fail.
Having worked with both sulfuric acid and hydrofluoric acid, I can confidently say they are both nasty customers. I want to know who the madman was that thought to combine them.
Ascorbic acid (vitamin C) is a pretty cool reducing agent IMO. I've found it to work just as well as sodium thiosulfate for cleaning up after handling elemental bromine (and it's a lot cheaper).
Water in C tier despite being in Soda 😡😡😡 Nitric and HC need to be S+. HCl is just too common, cheap, and useful. Conc Nitric Acid is a really useful oxidizer for rocket fuels.
For peptied sysnthesis in resins, we use a lot of TFA for the cut of the molecule from the resin, but there are some resisn that are way to acid resistent and you have to use some crazy acids like TMSB, Trifluoromethanesulfonic acid and HF + some salts. Also the TFA helps a lot in in the HPLC to see better the peaks and is good to clean the columns in the case some molecule gets stuck there.
Perhaps niche but Nafion membrane (basically sulfonated Teflon) has been useful in inorganic chem as well as organic catalyst. Similar to sulfonated polystyrene but inert to other reagents.
@@jheadley635 I am not really sure. presumably my institution uses it because it is "safe" enough to be used by a fist year undergrad, it is cheap cheap, and it being a solid powder is somewhat nice because it doesn't spread spills around.
Not sure if these are in there, but my S tier includes both aminocaproic acid and tranexamic acid. Both of them can be given to greyhounds before and after surgeries to prevent them bleeding out, and TXA saved my dog’s life when he had vasculitis this year. SS+ tier.
I know you said only common acids, but considering some of the other stuff here, I wish pentacyanocyclopentadiene was on here. It is a C-H superacid for crying out lout! And the symmetry! Wonderful molecule.
Vitamin C (as salts) is also useful as the only practical way of making pure sodium/potassium oxide in the lab, by thermal decomposition of the ascorbates. Alkali metal oxides are otherwise rather elusive or need some weird/dangerous methods of synthesis.
I do metal refining so hydrochloric, sulfuric, and nitric are definitely my top 3. I may look into ammonium chloride since from what he said it's very stable and chill 😎
Something that I was always curious about. Why is Phosphoric acid in soda? The only reason I could think of is that it was added back when soda came in steel cans to prevent rust, but not sure.
I think oxalic acid didn't get enough respect. It's pretty darn good at converting metal oxides to soluble forms. The coolest thing though is that it can be made from sugar and nitric acid.
@@That_Chemist But its common name is Cracktorio, which starts with a C, and since the gap between F and C is the same as between C and S, and it starts with C instead of F, it's clearly obviously S tier, duh.
9:35 I love when someone accidentally says citric acid, because they want to say ascorbic acid, but only thing they have in mind is vitamin C... and you know, it's sour, it has "C" in it, so why not citric acid, right?! :D
Seperate submission for "Acidic" columns like Alumina and Zeolites. Used on benchtop or for vapor phase reactions which cannot be done readily in solution.
Formic acid is great for treating warts. It's inexpensive and unlike vinegar, salicylic acid, and all those other over the counter treatments, it has over 95% success at treatment. You also only need (and want) to use it once every few days. The only real downside is it HURTS. 80 percent by volume is standard medical concentration for injection but if a doctor doesn't numb the patient first it should be considered a war crime. In my personal experience, 20 percent applied topically will do the job without being so painful you start to have a panic attack. Also it occurs to me that it is volatile and the fumes hurt to breathe in.
I know its a re-upload, so I'll repeat my comment. I think triflic acid deserves more credit. Megastrong acid but with a completely unreactive counterion. If you want a ultrastrong acid that can be measured accurately while not chewing up your substrate or glassware, or killing you, I can't think of anything better than triflic acid. It is the strongest acid there is that isn't volatile or oxidizing or otherwise destructive beyond its acidity alone. I used it to convert thioethyl glycosides to their corresponding azides using triflic acid, N-iodosuccinimide, and TMS-azide, which gave me the anomeric configuration (alpha) I wanted. I would buy it in 25g bottles and divvy it up between ampules I made from pipettes, containing about 1g each.
Perchloric acid is pretty awesome for making energetic complexes and other compounds whether metallic, organic or organometallic. 70% is more than strong enough, you don't really need the anhydrous form for anything that would be even close to safe. Picric acid isn't nearly as dangerous as it's reputation unless you're letting it come in contact with metals or their salts. If you keep it wet and in the right kind of container you won't have any problems.
I'd wondered why the sweetener version of saccharin is not just straight saccharin but rather a salt of an alkali metal (sodium saccharin, calcium saccharin are the ones I have seen). Turns out that the salt is needed to make it soluble in water and usable as a sweetener.
BINOL CPAs are not super difficult to make on scale and they’re a great excuse to do large scale lithiations. The triazole versions are a bit annoying though. Love the scaffold and their success has led to DSI catalysts with significantly lower pKa capable of doing enantioselective mukaiyama aldols and the IDPi catalysts from the List group are acidic enough to activate olefins in asymmetric hydroalkoxylations. Wouldn’t want to make one of those though.
I can’t believe benzoic acid only got A tier, should have been S because it’s in soda! They add sodium benzoate as a preservative. I’ll admit that fact maybe isn’t worth celebrating though.
Okay, finished the video, while I'm a little pissed you relegated all the biochem stars to C tier, I appreciate the consistency of the tiers in the video. (and yes, hypochlorous acid is absolutely rancid and as an acid barely counts so F tier, but damn is dissolved chlorine useful sometimes)
Normally, I'd be like "HF S-tier fuck yeahhhhh", because it's incredibly useful, but holy butt please God don't make me work with it. I'd give it at least D for extreme usefulness... Just keep it really fucking far away
Acetic acid is not strong, but it still has a very noxious smell, just like hydrochloric acid and still can cause severe and even fatal burns and eye damage, especially when ingested or being in concentrated form.
Flouroantimonic acid. 10^16 times stronger than H2SO4. One of the strongest superacids and it's just fucking cool. (I'm a physics major, don't judge me)
Why is my favourite acid (lsd) missing from this list?? I mean I don't need a video to tell me it's greater than S-tier, but still inclusion would've been nice.
Bit unclear whether the rankings were decided by synthetic utility or commonality in industrial/consumer products, seems like a mix of the two. One acid to add on the synthetic side - Brookhart’s acid, HBArF4/Et2O (diethyloxonium tetrakis(3,5-bis(trifluoromethyl)phenyl)borate) - fantastically strong acid useful for inorganic chemists when you need a rigorously non coordinating anion. Also vital for some group 4 metal-catalyzed polymer applications.
It's nice that hydrogen iodide was mentioned first. HI is such a warm greeting!
It really is
The DEA also gives a warm greeting.
@@Jokke13th 🤣🤣🤣
Omg you think you're so clever and you are I sure as hell am not :sigh:
my choice for best acid has unfortunately been schedule 1 since 1970.
but really though. sulfuric acid is like, the grandfather of modern chemistry. i’d very readily call it “the best acid” because it’s just so tried and true. also it makes piranha solution, which is my candidate for “scariest colorless liquid”.
The schedule 1 one probably saved my life lol. But tbh every subsequent time I've taken it after it saved my life was just recreative
@@magusperde365 only had it once, but it takes the cake for the most enjoyable experience of my life. need to get my hands on some again. :)
1970 was a really bad year for humanity, when some bafoons said "hey, your body is not your own" and just claimed humanity as its own to do what it will with. Because, if you don't own it, someone else does. Always.
@@gandalf8216and they're republicans.
@fictionindianspaceprogram-222 Ron Paul (Rand Paul’s father) was a Republican, then he turned into a libertarian and started advocating for ending the war on drugs. Timothy Leary even set up a donation event for his Presidential campaign. It’s dangerous to make generalizations like that because I don’t see many Democrats advocating for ending the War on Drugs.
Citric acid and ascorbic acid are the two I most often use in tankless water heater descaling, and as such I have a misplaced love for them. We used to use good old acetic acid, but few years ago a certain Japanese manufacturer's rep had us change to a less offensive smelling solution after going through comparison tests in the car park of the local hardware store. Got paid for a full day of watching someone else do my job 4-5 times in a row, and learned quite a bit in the process! All because a local plumber hated the smell of vinegar :)
John D. Clark's book Ignition! describes an interesting use of HF: In the late 1940s-early 1950s a very popular rocket propellant combination was a hydrazine and fuming nitric acid. This of course had two problems: hydrazine actively seeks out ways to kill you, and nitric acid will dissolve a flyable oxidizer tank no matter what you make it out of. You could PROBABLY make one out of fiberglass, but that would be heavy. Since the intent of using propellants that are liquid at room temperature is to be able to fill a rocket with propellant and wait until you want to fire it - maybe years, if the rocket has a warhead on it and there's no war at the present time.
In 1951, a new hire at Dr. Clark's lab came up with the weird idea that a fluoride coating on the inside of the tank would protect it from the nitric acid. They tried it and discovered it works well until the nitric acid dissolves the fluoride coating. His next bright idea was to make the coating self-healing by putting HF in the nitric acid...which actually worked. Now they call it "inhibited nitric acid."
Putting one very corrosive acid into another very corrosive acid to make the mixture less corrosive. Whoda thunk?
Interesting!
The thought process is actually really clever, but fuck having to actually work with that mixture.
Picric acid used to be a reagent in old labs. It used to be that reagent you looked for when buying an old lab, so you could get rid of it before it blew the door off its cabinet.
HF is actually useful when it comes to Silicon wafer processing. I've actually used it for dipping my silicon wafer in HF for only 10 seconds in my 2nd year at my Local Community College. My professor told us in very serious tone of not to get in on out skin or clothing (we are in a class 10000 cleanroom even though it's not the correct condition to be doing wafer processing, it was only for demonstration) and if we were to get on our skin, we need to get calcium gluconate (C12 H22 Ca O14) on the area where the HF landed on. From what my professor also said that you're not going to feel the acid on you but it will eat away as you mentioned. Btw if your wondering, I've never got any on me so I'm fine
I don't know if this is still the case, but it also used to be used in industry for giving lightbulbs a frosted finish
I can't help but wonder if we go to the same community college. I don't want to say the name of the college, but is the cleanroom at the far end of the third floor in a long skinny building?
@@RangerOfTheOrder maybe. Did the building have different business present inside?
@@union573 Yes, indeed it did. The world is a small place.
@@RangerOfTheOrder wow lmao never would I expect someone to be attending the same college I be at. Small world it is indeed
Nitric acid needs to be in S-tier man. Its one of the big three...
"If I was mean to benzoic acid, you guys would never let me hear the end of it, so I'm gonna put it in A tier just to suppress the hatred in the comments."
Guys, it's working. We're bullying him just enough. (great work as always m8 even if i haven't finished the video yet)
Haha
I like benzoic acid. It is the only handy way to make benzene in an amateur lab.
You can make benzoic acid at high yields from the pyrolysis of pet plastic so I think it is cool for that reason
@@sushiquad partial decarboxylation of therephtalic acid?
When one of the off-site higher ups found out we use perchloric acid in our analytical laboratory, where it is mixed with isopropanol to dissolve 4-dimethylbenzaldhyde. There were a few frantic phone calls to our lab manager, questions about the fumehood we use it in, though not the method if I recall, followed by a stop work order being issued. Not long after we were able to calm things down when we showed that we only use 70% HClO4, not the anhydrous stuff that likes to combust/explode on contact with organics.
If you do furniture refinishing, oxalic acid is useful for bleaching black stains caused by water penetrating the finish and soaking into the wood below. This often happens when someone overwaters a potted plant which is sitting on an end table.
one I'd add is carborane acids, which are stronger still than fluorantimonic acid - they can protonate benzene! - yet they're crystalline solids that are easy to store and handle
the complicated process of synthesis makes them impractical for large-scale use, but they do have a pretty cool shape (icosahedron)
Acid tier list but didn't even include the strongest acid of all time, helium hydride - smh, smh.
Person who actually enjoys working with HF here! In my last job, it was a daily to use it to homogenize up recycled fuel-samples - of course it was just a part of the whole ICP process, but I actually grew fond of it! The only minus I found, was doing the complexing after the actual melt, that was a pain in the ass because of all the vapors.
HClO4 at least C tier...its one of the reagents we have a heart for. You can crystalize out potassium with it when the solution is cooled.
High tier because of the roumers and the interesting salts.
Love your content
Thank you :)
My school chemistry was a nightmare. Almost only acids and bases for two years straight, which was only alkaline metals and sometimes hydrochloric acid. And phenolphthalein. Again and again. Our teacher was talking painstakingly slowly and was more worried about our handwriting than showing us something new. I would loved to have anything slightly complex, but the only other experiments I can remember were like heating iron with sulfur or his diy thermite fail.
Having worked with both sulfuric acid and hydrofluoric acid, I can confidently say they are both nasty customers. I want to know who the madman was that thought to combine them.
Ascorbic acid (vitamin C) is a pretty cool reducing agent IMO. I've found it to work just as well as sodium thiosulfate for cleaning up after handling elemental bromine (and it's a lot cheaper).
Cheaper and tastes better, as all chemistry reagents should.
Water in C tier despite being in Soda 😡😡😡
Nitric and HC need to be S+. HCl is just too common, cheap, and useful. Conc Nitric Acid is a really useful oxidizer for rocket fuels.
Yeah that’s fair
For peptied sysnthesis in resins, we use a lot of TFA for the cut of the molecule from the resin, but there are some resisn that are way to acid resistent and you have to use some crazy acids like TMSB, Trifluoromethanesulfonic acid and HF + some salts.
Also the TFA helps a lot in in the HPLC to see better the peaks and is good to clean the columns in the case some molecule gets stuck there.
Yeah that’s true - TFA and Formic acid are life savers in HPLC and LCMS
Perhaps niche but Nafion membrane (basically sulfonated Teflon) has been useful in inorganic chem as well as organic catalyst. Similar to sulfonated polystyrene but inert to other reagents.
Ammonium Chloride also tastes great, which cements it in S tier
Citric acid is great! We have it for cleaning up when some undergrad spills mystery base diluted in water.
Why do you use it as opposed to some other acid?
@@jheadley635 I am not really sure. presumably my institution uses it because it is "safe" enough to be used by a fist year undergrad, it is cheap cheap, and it being a solid powder is somewhat nice because it doesn't spread spills around.
I love the logic behind phosphoric acid’s placement lol
Valid
Not sure if these are in there, but my S tier includes both aminocaproic acid and tranexamic acid. Both of them can be given to greyhounds before and after surgeries to prevent them bleeding out, and TXA saved my dog’s life when he had vasculitis this year. SS+ tier.
De javu. I have seen this place before...
I know you said only common acids, but considering some of the other stuff here, I wish pentacyanocyclopentadiene was on here. It is a C-H superacid for crying out lout! And the symmetry! Wonderful molecule.
oh no way - cool
7:34 "TFA is definitely A tier"
*proceeds to put it in S tier*
totally well deserved S tier
TIL that saccharin aka "sweet n low" has a sulfur atom in it. No wonder it has that burned tire aftertaste!
Vitamin C (as salts) is also useful as the only practical way of making pure sodium/potassium oxide in the lab, by thermal decomposition of the ascorbates. Alkali metal oxides are otherwise rather elusive or need some weird/dangerous methods of synthesis.
oh yeah - interesting route
@@That_Chemist but somewhat less thrilling than melting potassium metal with potassium nitrate or potassium hydroxide
I stopped watching Breaking Bad to watch this and the meth joke ten second in took me off guard
The best acid is the one that shows me the secrets of the universe
Somebody needs to make a "That Chemist out of context" video
Do it
I do metal refining so hydrochloric, sulfuric, and nitric are definitely my top 3. I may look into ammonium chloride since from what he said it's very stable and chill 😎
Something that I was always curious about. Why is Phosphoric acid in soda? The only reason I could think of is that it was added back when soda came in steel cans to prevent rust, but not sure.
I heard the phosphoric acid keeps bacteria and mold out of it.
Like acetic acid in pickles
...and it probably tastes better than acetic ^^
Yeah
I think oxalic acid didn't get enough respect. It's pretty darn good at converting metal oxides to soluble forms. The coolest thing though is that it can be made from sugar and nitric acid.
Very cool!
Sulfuric acid appears in factorio. Immediate S tier in my books.
factorio starts with an f tho
@@That_Chemist But its common name is Cracktorio, which starts with a C, and since the gap between F and C is the same as between C and S, and it starts with C instead of F, it's clearly obviously S tier, duh.
Thank God factorio invented sulferic acid
9:35 I love when someone accidentally says citric acid, because they want to say ascorbic acid, but only thing they have in mind is vitamin C... and you know, it's sour, it has "C" in it, so why not citric acid, right?! :D
True
Seperate submission for "Acidic" columns like Alumina and Zeolites. Used on benchtop or for vapor phase reactions which cannot be done readily in solution.
I might do one on Lewis acids At some point
@@That_Chemist and lewis bases , too? T like Ammonia:Borane adduct.
Fluorosulfuric acid. Hydrolysis to HF and H2SO4 I'm thinking.. So bad. Triflic is magic acid isn't it? Awesome content keep them coming 👌
9:32 WOW. OKAY.
Lol
water, ascorbic and citric acid are all found in soda
True
Formic acid is great for treating warts. It's inexpensive and unlike vinegar, salicylic acid, and all those other over the counter treatments, it has over 95% success at treatment. You also only need (and want) to use it once every few days. The only real downside is it HURTS. 80 percent by volume is standard medical concentration for injection but if a doctor doesn't numb the patient first it should be considered a war crime. In my personal experience, 20 percent applied topically will do the job without being so painful you start to have a panic attack. Also it occurs to me that it is volatile and the fumes hurt to breathe in.
interesting!
the smell is like being stabbed in the brain
@@That_ChemistThere’s a story here
I feel that, as a Floridian, I have to take umbrage with citric and ascorbic acid being in C tier... Might just be my addiction to oranges.
Second chemist reporting for duty!
We once destilled HClO4 with 200 mg Plutonium in it to dryness (no vacuum). HI has to be higher because low pks value
Yikes
*_Plutonium_*
now you're working with radioactive stuff
I know its a re-upload, so I'll repeat my comment. I think triflic acid deserves more credit. Megastrong acid but with a completely unreactive counterion. If you want a ultrastrong acid that can be measured accurately while not chewing up your substrate or glassware, or killing you, I can't think of anything better than triflic acid. It is the strongest acid there is that isn't volatile or oxidizing or otherwise destructive beyond its acidity alone.
I used it to convert thioethyl glycosides to their corresponding azides using triflic acid, N-iodosuccinimide, and TMS-azide, which gave me the anomeric configuration (alpha) I wanted.
I would buy it in 25g bottles and divvy it up between ampules I made from pipettes, containing about 1g each.
It’s a really good acid
HCL is also made by the human body so definately above S tier.
Perchloric acid is pretty awesome for making energetic complexes and other compounds whether metallic, organic or organometallic. 70% is more than strong enough, you don't really need the anhydrous form for anything that would be even close to safe. Picric acid isn't nearly as dangerous as it's reputation unless you're letting it come in contact with metals or their salts. If you keep it wet and in the right kind of container you won't have any problems.
I'd wondered why the sweetener version of saccharin is not just straight saccharin but rather a salt of an alkali metal (sodium saccharin, calcium saccharin are the ones I have seen). Turns out that the salt is needed to make it soluble in water and usable as a sweetener.
The molecular biologist in me fells personally attacked by the vitamin c part...yikes
Tell them to get out of you - people shouldn’t be in you
@@That_Chemist Well, I don't know about that! With people you like...
If HCl was not S tier I'd riot, also nice windows noises around the 11:00 mark
F
HF dissolves glass, so it's used in semiconductor manufacturing.
as a scandinavian i can for sure say that amonium chloride is the best because of salmiakki
Oxalic acid is in Sorrel, and Sorrel makes a great Soup, so S tier for Sure
Etymology and antomology. Nice.
You should've put ascorbic acid in S-tier because it prevents scurvy! It's an essential nutrient that we need!
you're totally right!
and it causes kidney stones if you take too much
"[acetic acid] can be kind of annoying to get rid of"
*C O N S U M E*
BINOL CPAs are not super difficult to make on scale and they’re a great excuse to do large scale lithiations. The triazole versions are a bit annoying though. Love the scaffold and their success has led to DSI catalysts with significantly lower pKa capable of doing enantioselective mukaiyama aldols and the IDPi catalysts from the List group are acidic enough to activate olefins in asymmetric hydroalkoxylations. Wouldn’t want to make one of those though.
Cool!
7:40 the most Super acid definetly is C20H25N30, but I'm glad you didn't consider Things above S Tier
The issue with periodic acid is it only works every other day.
Haha
or once a month
With how much you've rated the smells of things, maybe *nose* pipetters could've worked, too 😅💀
Agreed - there is an amazing nose pipetter drawing on the discord from when we played jackbox
I can’t believe benzoic acid only got A tier, should have been S because it’s in soda! They add sodium benzoate as a preservative. I’ll admit that fact maybe isn’t worth celebrating though.
Wait really 😭
Yeah
I was goingto say Lysergic Acid diethylamide but I'd probably get put on a watch list.
can you please make a video for the best method to grow crystals?
It’s honestly a skill which you need to hone - it’s more of an art
Okay, finished the video, while I'm a little pissed you relegated all the biochem stars to C tier, I appreciate the consistency of the tiers in the video. (and yes, hypochlorous acid is absolutely rancid and as an acid barely counts so F tier, but damn is dissolved chlorine useful sometimes)
the one thing bio chemicals have going for them is that they are fairly reliable
Helium hydride only occurs in a vacuum because it protonates anything it comes into contact with...
Am I the only one clicking on this video because of a different kind of "acid" ? 🤣
Ayo where the fluoroantimonic acid at
HSbF6
What about the pi acids like CO?
"This explodes so it can go into E tier" for entertaining!
acidic polystyrene?
Does it look like the polystyrene used for packaging?
Next: which Lewis acid is best
It will happen sooner or later
Not a chemist just watching this guy rate acids
heck yes
I'm a huge fan of fluoroantimonic acid. Is that actually the strongest one?
Strongest we have measured properly
Do an oxidizer tier list
th-cam.com/video/TiDgYKq6n_A/w-d-xo.html
In German formic acid ist literally called ant acid (Ameisensäure)
Normally, I'd be like "HF S-tier fuck yeahhhhh", because it's incredibly useful, but holy butt please God don't make me work with it.
I'd give it at least D for extreme usefulness... Just keep it really fucking far away
Acetic acid is not strong, but it still has a very noxious smell, just like hydrochloric acid and still can cause severe and even fatal burns and eye damage, especially when ingested or being in concentrated form.
Do one for bases
Which Bases are Based?
th-cam.com/video/4PYmUOI_f3c/w-d-xo.html
What will happen, if you mix sulfamic acid and fluorosulfonic(chlorosulfonic) acid? 🤔🤔🤔
Lysergic acid diethylamide
Great tier list, apart from one thing...
*NITRIC ACID BELONGS TO S-TIER!!!*
my dealer gets me some really good acid, had the best tr-- oh wait nevermind
🥸
Hmm, acetic acid. Add sodium bicarbonate and you can clean stuff
"It's actually useful for semiconductors / nuclear enrichment / exotic rocket fuel"
*automatic F tier never going within a 10 kilometer radius*
Haha
Flouroantimonic acid. 10^16 times stronger than H2SO4. One of the strongest superacids and it's just fucking cool. (I'm a physics major, don't judge me)
It is cool
Is it bad if I use this to fall asleep even though I love chemistry?
That’s amazing
Lysergic imo
boric acid is great put it in my shoes it cost me 10 euro for only 100 gram but its worth it
I know im biased as I'm a water drinking fan, but im kinda sad you put water on C tier. Water is high tier only if you're not into chemistry it seens.
Plus it’s in soda so it should have been S tier
Why is my favourite acid (lsd) missing from this list??
I mean I don't need a video to tell me it's greater than S-tier, but still inclusion would've been nice.
It isn’t chemically an acid
10:55 What the fuck is sending alerts on my computer?
Dihydrogen Monoxide is an acid with a PH of 7. That's a higher PH than any other acid!
Bit unclear whether the rankings were decided by synthetic utility or commonality in industrial/consumer products, seems like a mix of the two.
One acid to add on the synthetic side - Brookhart’s acid, HBArF4/Et2O (diethyloxonium tetrakis(3,5-bis(trifluoromethyl)phenyl)borate) - fantastically strong acid useful for inorganic chemists when you need a rigorously non coordinating anion. Also vital for some group 4 metal-catalyzed polymer applications.
Yeah it’s a great acid
WHERE'S TINKYWINKENIC ACID
Soda makes chemistry happen.
I think we all know which acid is the true a tier.
lysergic?
edgy
@@That_Chemist hopefully I don't get in trouble. It is some low hanging fruit
...none of which are lysergic acid diethylamide. I feel let down.
Why did you reupload this video ?
The old channel wasn’t monetized
@@That_Chemist ok then