Can't say it in better Words than John Michael. You Sir, are a brilliant teacher and you just helped a medicine student from Germany to pass the first (and most feared) part of his finals. Thank you so much!
Love your videos! I'm in medical school and every time I see the Khan Academy I instantly get excited because I know you guys will explain it clearly and concisely
This was great! Thank you. Just one thing I don't quite understand... for the Haldane Effect, its a straight line. The slope of the line decreases. Doesn't that cause the amount of CO2 in the thighs to change as well as in the lungs? Why are you able to compare the point for thigh on the blue line (without the Haldane Effect) to the point for lungs on the purple line which includes the Haldane Effect?
Not really as even if the slope is changing, the y intercept will still stay at the level of the initial one although might be a little late to get there
i love khan academy soooooooo much! like i have sooo much love for you guys!! first you helped me ace my a levels and now you're making uni soo much more easier and enjoyable for me
Rimel, if you're actually in uni you should know not to use the adverb/modifier 'more' with an adjective that uses -er/-est. So it should be "...much easier or more easy..."
Thank you so much for the great explanation! I'm not sure if someone has already asked you this but I was wondering what kind of equipment you are using to both record and draw out your explanations? Thank you for your time and I hope to hear from you soon.
Thanks for the video! This video helped me a lot! Although one note for other viewers would be that you need to have some understanding of the mechanisms involved to really grasp this concept. So if you watched this and didn't really understand it yet, go ahead and read up to remind yourselves of the principles of respiration: How gases such as O2 and CO2 move in and out of the body via the lungs. Concepts like Cooperativity and the principles of Hb affinity are also important, but this video covers it a bit.
Omg, omg, omg. lol Thank you soooo much for creating this video. I read my textbooks and was like WHAT???? Found this video and understood every word. Thanks so much for making my learning easier. :)
The difference between the oxygen content delivered (just after leaving the lungs) and the oxygen content after tissue metabolism does not equal O2 delivery, it equals o2 consumption or demand (Vo2).Am I confused?
Hi! Thank you for the video! I am not a med student and just starting to learn physiology, please excuse my ignorance but why thigh comes earlier on the graph of Bohr effect then lungs?
the question is why in a COPD exacerbation does high level of O2 reduce the uptake of CO2 from the tissue via haldane effect? I understand that O2 vasodilates their lungs and there is alot of shunting of RBCs and thus higher levels of CO2 so thats factors in to the high CO2 levels but can you please explain why High O2 reduces CO2 uptake from tissue because from your illustration it seems that you are saying more O2 means more CO2 delivery to the lungs..
This was really insightful. What I don't understand though: how come oxygen saturation is 95-99% in the finger? And why is it the same in my toe? Yes I tested it with an oxymeter!
Just something that was confusing for the Haldane effect. You kept saying that the x axis is the "amount of CO2 in the blood" and that the y axis is the "content of CO2" in the blood, it didn't seem as though the distinction was as clear as it could have been.
Beautifully explained, thank you so much for making this crystal clear :O, I have tried time and again, to understand this concept, and never really managed to until I bumped into this video :)
for Haldane effect how are u taking thigh point on one curve and the lung point on the other curve & then taking the difference of CO2 and then showing that there is a inc in CO2 delivery? i am confused shouldn't both points be on the same curve if ur taking the difference
I'm having some trouble understanding the role of the Haldane effect when giving oxygen to emphysematous patients. If you increase O2 you get decreased H+ and CO2 binding to hemoglobin but increased CO2 delivery to the lungs?
God bless you. There are only a handful of people who can teach like u can. Mashallah
Crct my friend
❤❤
Can't say it in better Words than John Michael. You Sir, are a brilliant teacher and you just helped a medicine student from Germany to pass the first (and most feared) part of his finals. Thank you so much!
You might like the Double Bohr effect as well. Pretty neat phenomenon...
Praise God that I found you!!! I can now understand what's going on in class!
Love your videos! I'm in medical school and every time I see the Khan Academy I instantly get excited because I know you guys will explain it clearly and concisely
Got me through my biochemistry module! My lecturer had no skills of explanation!
Same here.
Means this comment is in 2014 waoo in that time I am in 3rd now in 12😮
My lecturer somehow explained it in a way that I thought the two weren't even related. Thanks for clearing things up.
You're welcome...We will be getting into Double Bohr soon! =)
There's more? o.O
@@kittendivine1 🤣 lol
Just wanted to let You guys know that you are freaking awesome!💐
What did humanity do to deserve you 🥺
This was great! Thank you.
Just one thing I don't quite understand... for the Haldane Effect, its a straight line. The slope of the line decreases. Doesn't that cause the amount of CO2 in the thighs to change as well as in the lungs? Why are you able to compare the point for thigh on the blue line (without the Haldane Effect) to the point for lungs on the purple line which includes the Haldane Effect?
i thought the same thing, maybe its an error on their part
Not really as even if the slope is changing, the y intercept will still stay at the level of the initial one although might be a little late to get there
I wish my teacher could explain just like you. EXCELLENT!
It makes so much sense on a detailed level now. Thank you.
Wow, this is an excellent explanation!!!! I was very confused about these two concepts but now I totally understand. Thank you very much!
i love khan academy soooooooo much! like i have sooo much love for you guys!! first you helped me ace my a levels and now you're making uni soo much more easier and enjoyable for me
Rimel, if you're actually in uni you should know not to use the adverb/modifier 'more' with an adjective that uses -er/-est. So it should be "...much easier or more easy..."
Thank you so much for the great explanation! I'm not sure if someone has already asked you this but I was wondering what kind of equipment you are using to both record and draw out your explanations? Thank you for your time and I hope to hear from you soon.
Thanks for making the Bohr effect and Haldane effect so easy to understand :)
Thank you Dr. Desai !!
Thanks for the video! This video helped me a lot! Although one note for other viewers would be that you need to have some understanding of the mechanisms involved to really grasp this concept. So if you watched this and didn't really understand it yet, go ahead and read up to remind yourselves of the principles of respiration: How gases such as O2 and CO2 move in and out of the body via the lungs.
Concepts like Cooperativity and the principles of Hb affinity are also important, but this video covers it a bit.
this explanation is a lot better than the one my teacher gave me! Thanks for explaining! :D
This explanation deserves a prize!
............this was epic, thank you, got a Physiology test tomorrow, this helped.
This is the best physiology video I’ve seen in my entire life and will definitely help in my upcoming oral exam, wow.
This concept has been an re-occuring issue for me in respiratory phys. This video cleared up my confusion. Thanks!!
Omg, omg, omg. lol Thank you soooo much for creating this video. I read my textbooks and was like WHAT???? Found this video and understood every word. Thanks so much for making my learning easier. :)
The Greatest teachers and professors are here ♥️♥️♥️
The difference between the oxygen content delivered (just after leaving the lungs) and the oxygen content after tissue metabolism does not equal O2 delivery, it equals o2 consumption or demand (Vo2).Am I confused?
No that's correct
you saved our lives thank you
One of the best revision videos I have ever seen. Cheers!
one of the most comprehensive videos on this very ignored topic. thank you
Thanks so much. I'm a BScN student, and a visual learner. The way you have presented the material has helped me immensely!
Khan Academy coming through to save my grade again!
I looked up this video , an hour before my premed final , and the exact same question came up . Thanks Mr. Khan .Go raibh maith agat as Eireann
The one thing I would edit is posing the change in the graph of the Bohr affect as a decrease in slope instead of a horizontal shift.
One thing to clear out is that CO2 has a different binding site on hemoglobin (combines with the globin portion), so it's not a competitive binding.
Very well explained both visually and orally, thanks a lot.
your voice is made for this! thank you!
Gracias por este vídeo! me ha servido de mucho!
Ailin Monti igualmente
Thank you so much!! Your videos are helping me through my RN program!
I'll definitely check it out ! Thank you so much
God bless you. You just made my day after struggling to figure this out, you simplified in the best possible way. Thank u!
your videos are just the best form of revision ever
Can't thank you enough! ❤
3:25 6:20❤ 8:25
You are a god. I wish all professors were as clear as you. It would save hours of headaches.
Perfect explanation🤩
Brilliant..Hats off
Excellent as always. Thank you
I was struggling a lot with this, thanks!
Very helpful, thanks.
Thank you sir!
Wow bless you! My professor is awful but you explained things perfectly.
Thx for this awesome vid! Btw what kind of software did you use to present?
Thank you for a very clear discussion.... :)
Sir very clear concept ... hope this will help our budding doctors.
Hi! Thank you for the video! I am not a med student and just starting to learn physiology, please excuse my ignorance but why thigh comes earlier on the graph of Bohr effect then lungs?
the question is why in a COPD exacerbation does high level of O2 reduce the uptake of CO2 from the tissue via haldane effect? I understand that O2 vasodilates their lungs and there is alot of shunting of RBCs and thus higher levels of CO2 so thats factors in to the high CO2 levels but can you please explain why High O2 reduces CO2 uptake from tissue because from your illustration it seems that you are saying more O2 means more CO2 delivery to the lungs..
Raja Suri in copd patients you will have higher levels of CO2 and lower O2 levels.
Thank you so much for this, super helpful!
Khanz are best in every field
I have to present a seminar on the same. ..thank you for helping me out...
On point.
there is no practice section? I'd like to solve the questions.. Anyway thanks for great explanation!
you make the concepts Amazingly simplified! too good..😃👌👌
wow im impressed, god bless u.......u made it so easy 4 me to understand
U guys are just great! Love the black background
Thank you
THANK YOU I WAS SO CONFUSED IN CLASS NOW I GET IT
The best possible explanation ❤️
clear explanation :)
Thanks! I kind of understand! need to watch this twice though! xD
Omg! I finally understand these effects.
Thank you so much..
Was great sir ☺️.
Dear human being, i thank you very much!
Very good explanation, thanks
This was really insightful. What I don't understand though: how come oxygen saturation is 95-99% in the finger? And why is it the same in my toe? Yes I tested it with an oxymeter!
thanks a lot!
Dang Sir....Best explanation Ive seen so far.I Salute sir.
Just something that was confusing for the Haldane effect. You kept saying that the x axis is the "amount of CO2 in the blood" and that the y axis is the "content of CO2" in the blood, it didn't seem as though the distinction was as clear as it could have been.
thank you so much!!!! you saved me
Thankyou sir for this great and important explaination 🙏🙏
love your videos i,will be medical man some year coming and every time i see the khan academy
crystal clear
Beautifully explained, thank you so much for making this crystal clear :O, I have tried time and again, to understand this concept, and never really managed to until I bumped into this video :)
for Haldane effect how are u taking thigh point on one curve and the lung point on the other curve & then taking the difference of CO2 and then showing that there is a inc in CO2 delivery? i am confused shouldn't both points be on the same curve if ur taking the difference
I just noticed the same thing. Anyone care to elaborate?
Khan Academy, you've never let me down. Lots of love and gratitude!!
Best video ever
you are a great teacher!
thank you so much:)
Very helpful
you guys grat job..keep it up
Excellent explanation
thanks
thank you so much
very good & useful
thank u a lot... its really good for understanding... its help me a lot
Thank you so much! Great explanation! Hundred likes
Great explaination👌
Good job
I'm having some trouble understanding the role of the Haldane effect when giving oxygen to emphysematous patients. If you increase O2 you get decreased H+ and CO2 binding to hemoglobin but increased CO2 delivery to the lungs?
great Job !!! you've helped me a lot !!!
impressive
great vid
cristal clear
THIS IS GREAT, BRAVO ! Would love to see some Immunology from you. keep it up
what causes the oxygen molecules to behave cooperatively? why don't they just bind linear/proportional to the partial pressure as well?