starling law is about the size of a contraction. when the myocard is stretched, sarcomeres have more space between each other so they can contract more and vice versa. the more stretched the heart, the bigger the following contraction. LAplace's law is about tension on the walls. If the heart is (pathologically) dilated, LV has bigger radius thus greater the tension on the walls when contracting. on the other hand, hypertrophied heart has thicker wall, so the load on the wall is lower
Your point on the starling law needs some modification, it's a stronger contraction in a certain range, outside of that from fibers that are too stretched loose their ability to contract optimally
What a perfect explanation, I now understand why the concentric hypertrophy of the heart can lower the wall tension in the left ventricular chamber, by increasing the widht of the chamber. I only can think human body is amazing!
zaidbassist concentric hypertrophy doesn’t lead to an increase in ventricular diameter width; quite the opposite, it actually makes the ventricular wall diameter smaller. Hence, the ejection fraction (EDV - SV) is usually supranormal (doesn’t necessarily mean the overall cardiac function is preserved) as the cavity becomes smaller. I think you are referring to the why the increase in the wall thickness makes the overall tension less
thank you so much the last freaking sentence solved my problem...the thicker the wall the more desmosomes...and same for all other thick walled spherical objects. wow!
So, Leplace's Law is the tension and how stretched out the walls are and Starling Law is more stretch causes higher contraction between the Myosin and Actin, is that right?
can somebody explain me what does my teacher wants to say : the parietal stress is directly proportional to the tension in the wall isn't it the same thing? like what the fluff?
i have a question ... according to laplace law ..the more end-diastolic volume will increase the radius which oppose or decrease the myocardial contractility force forexample that at congestive heart failure we give venodilator and diuretics to decrease venous return therefore decrease enddiastolic volume and radius so heart can pump well...but but but according to frank starling more the more preload = venous return = end diastolic volume ..the more myocadial tension and forcefull contraction.
Thank you very much because of your question I am able to slightly think about what's the ,actually meaning of these 2 law,in my opinion,Laplace law tell us about heart oxygen demand requirement as,you said in congestive heart failure we give venodilators and diuretics to decrease venous return ,so pressure oh heart decreases and as heart is going in congestive heart failure,due to lack of oxygen,so only method here to prevent heart is by providing it with enough oxygen ,or reducing its oxygen demand so here in this case by doing so we actually reduces its oxygen demand and try to protect it, In Frank starling law more venous return more end diastolic volume leads to more contractility and and hence increase Stoke volume and ultimately cardiac output that's it,,,,but if heart is going undercongestive heart failure,we are required to put less pressure on heart so that it's oxygen demands get filled
Aside from the reply below, also take into account that starlings law applies to a certain range of myofibril stretch, outside of that range the fibers are too stretched by venous return for example and thus reduce their contractile ability
god bless the augmenting video speed option!great lesson to review really
starling law is about the size of a contraction. when the myocard is stretched, sarcomeres have more space between each other so they can contract more and vice versa. the more stretched the heart, the bigger the following contraction. LAplace's law is about tension on the walls. If the heart is (pathologically) dilated, LV has bigger radius thus greater the tension on the walls when contracting. on the other hand, hypertrophied heart has thicker wall, so the load on the wall is lower
*laplace law = tension in the walls
Your point on the starling law needs some modification, it's a stronger contraction in a certain range, outside of that from fibers that are too stretched loose their ability to contract optimally
could you also say that the wall pressure is another term for tension?
What a perfect explanation, I now understand why the concentric hypertrophy of the heart can lower the wall tension in the left ventricular chamber, by increasing the widht of the chamber. I only can think human body is amazing!
zaidbassist concentric hypertrophy doesn’t lead to an increase in ventricular diameter width; quite the opposite, it actually makes the ventricular wall diameter smaller. Hence, the ejection fraction (EDV - SV) is usually supranormal (doesn’t necessarily mean the overall cardiac function is preserved) as the cavity becomes smaller.
I think you are referring to the why the increase in the wall thickness makes the overall tension less
DOOM Hypertension: RIP AND TEAR.
Myocardium: no. **actively expands**
thank you so much the last freaking sentence solved my problem...the thicker the wall the more desmosomes...and same for all other thick walled spherical objects. wow!
So, Leplace's Law is the tension and how stretched out the walls are and Starling Law is more stretch causes higher contraction between the Myosin and Actin, is that right?
I think that's right!
Thank you
Now the topic makes a sense
Been searching everywhere. This is THE BEST explanation. Can count on Khanacademy to deliver
You can't search this video everywhere. It's always available.
Is this guy the voice of the Honey Badger video? Is he really pretty badass!?!?!?
Thank you very much!
Thank god for Khan
Thanks khan ! :)
tq so much for your help and support for the explanation................
amazing, thanks
can somebody explain me what does my teacher wants to say : the parietal stress is directly proportional to the tension in the wall
isn't it the same thing? like what the fluff?
Would it be a correct analogy to think of Desmosomes as rivets on a plane or a building?
Keep up the good work👏🙏🤛👌
Is there a quiz test for this theme on the khanacademy platform?
i have a question ...
according to laplace law ..the more end-diastolic volume will increase the radius which oppose or decrease the myocardial contractility force forexample that at congestive heart failure we give venodilator and diuretics to decrease venous return therefore decrease enddiastolic volume and radius so heart can pump well...but but but according to frank starling more the more preload = venous return = end diastolic volume ..the more myocadial tension and forcefull contraction.
Thank you very much because of your question I am able to slightly think about what's the ,actually meaning of these 2 law,in my opinion,Laplace law tell us about heart oxygen demand requirement as,you said in congestive heart failure we give venodilators and diuretics to decrease venous return ,so pressure oh heart decreases and as heart is going in congestive heart failure,due to lack of oxygen,so only method here to prevent heart is by providing it with enough oxygen ,or reducing its oxygen demand so here in this case by doing so we actually reduces its oxygen demand and try to protect it,
In Frank starling law more venous return more end diastolic volume leads to more contractility and and hence increase Stoke volume and ultimately cardiac output that's it,,,,but if heart is going undercongestive heart failure,we are required to put less pressure on heart so that it's oxygen demands get filled
@@mukeshrajput4478 yes
Aside from the reply below, also take into account that starlings law applies to a certain range of myofibril stretch, outside of that range the fibers are too stretched by venous return for example and thus reduce their contractile ability
Why 2w?
8:25 woah, that made me dizzy.
Wawwww
so i think both laplace law and starling law are opposite to each other or what !!!
please i need an explanation
r