Profiling Age and Body Fluid DNA Methylation Markers

DNA methylation plays a key role in physiological processes including regulating gene expression and is a widely used biomarker for age prediction and the identification of body fluids.
Traditionally, methylation detection relies on independent targeting of CpG sites as part of a multiplexed assay, which requires a complex, multistep workflow.
During this webinar, our expert speaker presented a new approach - using nanopore adaptive sampling for comprehensive methylation profiling.
They then illustrated how nanopore adaptive sampling successfully corroborated known CpG markers for age and body fluids as well as identifying potential new age-related methylation sites, outlining its potential in forensics and the clinic.