Hey leah, I understand that Tosylate makes OH into a better leaving group due to resonance but you mentioned PBr3 and SOCl2 are also used. I understand resonance could also contribute to SOCL2's ability to convert OH into a better leaving group, but I don't really see how PBr3 converts OH into a better leaving group. Is it because the Br atoms attached to Phosphorus atom are electron withdrawing which will make it a more stable anion after an SN2 reaction and thus a better leaving group? Any help would be much appreciated!
Bro, when you take socl2 for reaction in presence of pbr3 with alcohal that goes under "sni( I.e. intermolecular substitution reaction, a typ of substitution) reaction.
The key is to look at each mechanism individually and ask 'what about this new group makes it more stable once I kick it out?' each group is different with the same outcome, OH- will not form in solution
thank you! so helpful for the mcat!
Glad it was helpful!
Hey how'd the mcat go?
Thanks for such a nice explanation now I am understanding mechanisms well keep it up
You're welcome! Glad the video helped you understamd the topic.
Such a beautiful lecture
No where on youtube this concept is explained in such a way
I'm glad it helped you understand!
Where can I donate to you? These are so so helpful
No need to donate, just share my resources with others!
Oxygen as a leaving group? More like "Amazing lectures that are leading us; whoop!" 👍
Whoop whoop!!!
@@Leah4sci There it is
Hey leah,
I understand that Tosylate makes OH into a better leaving group due to resonance but you mentioned PBr3 and SOCl2 are also used. I understand resonance could also contribute to SOCL2's ability to convert OH into a better leaving group, but I don't really see how PBr3 converts OH into a better leaving group. Is it because the Br atoms attached to Phosphorus atom are electron withdrawing which will make it a more stable anion after an SN2 reaction and thus a better leaving group? Any help would be much appreciated!
Bro, when you take socl2 for reaction in presence of pbr3 with alcohal that goes under "sni( I.e. intermolecular substitution reaction, a typ of substitution) reaction.
The key is to look at each mechanism individually and ask 'what about this new group makes it more stable once I kick it out?' each group is different with the same outcome, OH- will not form in solution
thanks for sharing the video
You're so very welcome!
Thank you so much!! :)
You're very welcome!
hey leah among alkane sulphonate ion, alkyl sulphate ion and tosylate ion whats the order of leaving groups?
At which part of the video please?