I have always been amazed at Peter Attia's interviewing skills. This conversation showcases that beautifully. It also highlights another thing about Dr. Attia, he seems to have preexisting connections to so many consequential thinkers. For those few that he doesn't have past connections, his insightful questions and comments seems to open people up and allow for really deep and illuminating discussions. Dr. Deisseroth's eloquence and insight are remarkable. Very informative and enjoyable. Thanks Dr. Attia and Dr. Deisseroth.
This discussion was profound in a way I didn't expect. I found myself thinking about how I switched from being a social worker to an engineer in my 30s...the kinds of choices your brain gives you makes all the difference.
Just out of curiosity why did you switch ? I am actually going INTO social work in my 40s to help teenagers addicted to drugs. It's a lot more rewarding than finance :) Too bad they are polar opposites on income lol
FANTASTIC conversation Peter! I was recently introduced to Karl through Andrew Huberman's podcast, and I immediately bought and read his book- which I agree is beautifully written and incredibly insightful. I hope to see more of him and his work in the near future. Thanks again for your continual outstanding interview on your podcast🙏 💜🤗
I'm filled with an enormous respect and gratitude to Peter for his way, style of interviewing such a gem like Karl. And I'm gonna leave it right here, because it's really too much for me to carry furthermore and not develop some sort of fangirling symptoms.) Thank you Peter, it was a great pleasure and a perfect introduction, of surely course now Karl's book is at the top of my reading queue.
Interviewer and the guest both are great in their roles of asking and answering questions, very profound which I did not expect before watching the podcast, top notch stuff
Amazing stuff. Since our society won't return to a state that is conducive to mental health, we need to find ways to adapt. Thank you for sharing these fascinating insights into cutting edge neuroscience.
What an interesting part of life that is unknown to the general masses that affects directly or indirectly everyone in different aspects of their life. Thanks for sharing.
I’m speechless. To Peter and the drive, please keep up the great invaluable work. I’m continually inspired and motivated by the depth and wealth of knowledge this podcast brings to bare. ~ just another college student
I'm very curious what you both think of Dr. Daniel Amen's practice in using "SPEC Scans" in diagnosis of mental health and imperfections in healing brain issues? 🤔👌
Great question and while SPECT is a good marketing tool targeted at providing answers to some of the questions addressed in this episode, the literature on SPECT/fmri/advanced imaging very much lacks the specificity required to be a guide to current DSM-bound treatment options that exist. Ultimately this is an assessment tool at it's best and the treatments (in this case medications primarily) will be similar. I imagine most of the effects have to do with expectation of benefit (which is a very, very, very strong treatment in and of itself). Most of what SPECT literature shows is that you can see certain patterns of blood flow that are correlated with certain behavioral or emotional experienes. A good therapist or psychiatrist and an insightful person seeking help can arrive a subtype that might help guide treatment without a costly scan not covered by insurance :) This is a nice way to say Dr. Amen is an excellent salesperson and believing that something will work does indeed matter, but unlikely that SPECT has a large value add as the treatment options will likely look quite similar. Full disclosure I am a skeptic who has strong disdain for snake oil, and that's how I view Dr. Amen's work.
@@oakf-l3u I like what you had to say and I agree! My son had a SPECT scan at Amen clinic about 6 months ago. Although it was interesting to see, all in all it was not worth 4K for my son's issues. It may be beneficial for many people but my son has high functioning autism and suffers from rumination and OCD, and has anger and mood issues. So a normal person who follows Amen's recommended protocol of good diet, exercise, meditation, and supplements along with CBT, may see great results. The scan just tells you where your brain is overactive or underactive which is probably apparent with just symptoms and observation. I think that money would have been better spent (for my son) by hiring a mindfulness meditation therapist, and a personal trainer. TMS (transcranial magnetic stimulation) is good if one suffers from depression.
@@VeryLikeLeigh Have you tried Dr. Natasha Campbell GAPS diet? Have you read from the work of Dr. Jack Kruse, mitochondria, SunLight, nature exposure, grounding? These are non-expensive everyday lifestyle implementations that may add to the betterment basket🙏🏻.
Interesting podcast! Curious if there is any research regarding what percentage of psychiatric patients have illnesses that are correctable physiological malfunctions versus a purely genetic presentation of illness.
Does anyone know the book Dr. Attia is referencing regarding hypomania as an evolutionary construct? I believe he said the Psychiatrist is or was from Johns Hopkins.
Likely referencing Kay Redfield Jamison if JHU and bipolar dx. Not sure if she's published extensively on evolutionary psychology but she's pretty big in the field.
Re: the genetic component of mental disorders. It's 2022. I think it's about time to start considering in utero factors as separate from "genetics". Just because monozygotic twins raised apart share a lot of diagnoses does not mean that the component to the disorder is predominantly genetic. Stable mothers in ideal environments don't give their children up for adoption. The mother's stress/hormonal levels, whether the birth was traumatic, the neglect or lack of bonding post partum, etc - these are all factors that contribute to development significantly, and it is reductionistic to not consider them when discussing the root of mental disorders / adaptation variance.
Very interesting episode! Ketogenic Diet seems to help to sustain the "energy issues" with Bipolar disorder, according to studies the shifting in states might be related to impaired glucose "burning" / insulin resistance, due to genetic components that results in mitochondria dysfunction. This resonated well with my own experience having Bipolar II and feeling better on Keto: th-cam.com/video/x51HuJq0YCw/w-d-xo.html
I have always been amazed at Peter Attia's interviewing skills. This conversation showcases that beautifully. It also highlights another thing about Dr. Attia, he seems to have preexisting connections to so many consequential thinkers. For those few that he doesn't have past connections, his insightful questions and comments seems to open people up and allow for really deep and illuminating discussions. Dr. Deisseroth's eloquence and insight are remarkable. Very informative and enjoyable.
Thanks Dr. Attia and Dr. Deisseroth.
I am still sitting here amazed at how Dr. Diesseroth can simplify his work down to such a digestible level so effortlessly. Amazing pod!
Peter’s compassion is real and evident. Great guest and conversation.
This discussion was profound in a way I didn't expect.
I found myself thinking about how I switched from being a social worker to an engineer in my 30s...the kinds of choices your brain gives you makes all the difference.
Just out of curiosity why did you switch ?
I am actually going INTO social work in my 40s to help teenagers addicted to drugs. It's a lot more rewarding than finance :)
Too bad they are polar opposites on income lol
@@stevrgrs💵💵💵
The brilliance clearly evident in this conversation fills my heart with gratitude......Thank you, Dr. Attila and Dr. Deisseroth!
FANTASTIC conversation Peter! I was recently introduced to Karl through Andrew Huberman's podcast, and I immediately bought and read his book- which I agree is beautifully written and incredibly insightful. I hope to see more of him and his work in the near future. Thanks again for your continual outstanding interview on your podcast🙏 💜🤗
I'm filled with an enormous respect and gratitude to Peter for his way, style of interviewing such a gem like Karl. And I'm gonna leave it right here, because it's really too much for me to carry furthermore and not develop some sort of fangirling symptoms.) Thank you Peter, it was a great pleasure and a perfect introduction, of surely course now Karl's book is at the top of my reading queue.
Interviewer and the guest both are great in their roles of asking and answering questions, very profound which I did not expect before watching the podcast, top notch stuff
Amazing stuff. Since our society won't return to a state that is conducive to mental health, we need to find ways to adapt. Thank you for sharing these fascinating insights into cutting edge neuroscience.
The excitement i feel for this episode is comparable to a “kid in a candy shop”
What an interesting part of life that is unknown to the general masses that affects directly or indirectly everyone in different aspects of their life. Thanks for sharing.
I’m speechless. To Peter and the drive, please keep up the great invaluable work. I’m continually inspired and motivated by the depth and wealth of knowledge this podcast brings to bare. ~ just another college student
I'm very curious what you both think of Dr. Daniel Amen's practice in using "SPEC Scans" in diagnosis of mental health and imperfections in healing brain issues? 🤔👌
I’ve wanted one of those for so long.
Great question and while SPECT is a good marketing tool targeted at providing answers to some of the questions addressed in this episode, the literature on SPECT/fmri/advanced imaging very much lacks the specificity required to be a guide to current DSM-bound treatment options that exist. Ultimately this is an assessment tool at it's best and the treatments (in this case medications primarily) will be similar. I imagine most of the effects have to do with expectation of benefit (which is a very, very, very strong treatment in and of itself). Most of what SPECT literature shows is that you can see certain patterns of blood flow that are correlated with certain behavioral or emotional experienes. A good therapist or psychiatrist and an insightful person seeking help can arrive a subtype that might help guide treatment without a costly scan not covered by insurance :)
This is a nice way to say Dr. Amen is an excellent salesperson and believing that something will work does indeed matter, but unlikely that SPECT has a large value add as the treatment options will likely look quite similar.
Full disclosure I am a skeptic who has strong disdain for snake oil, and that's how I view Dr. Amen's work.
@@oakf-l3u I like what you had to say and I agree! My son had a SPECT scan at Amen clinic about 6 months ago. Although it was interesting to see, all in all it was not worth 4K for my son's issues. It may be beneficial for many people but my son has high functioning autism and suffers from rumination and OCD, and has anger and mood issues. So a normal person who follows Amen's recommended protocol of good diet, exercise, meditation, and supplements along with CBT, may see great results. The scan just tells you where your brain is overactive or underactive which is probably apparent with just symptoms and observation. I think that money would have been better spent (for my son) by hiring a mindfulness meditation therapist, and a personal trainer. TMS (transcranial magnetic stimulation) is good if one suffers from depression.
@@VeryLikeLeigh Bro/Sis, thanks for sharing your experience. Everyone who reads it can benefit. That’s the value of the internet in its purest form.
@@VeryLikeLeigh Have you tried Dr. Natasha Campbell GAPS diet? Have you read from the work of Dr. Jack Kruse, mitochondria, SunLight, nature exposure, grounding? These are non-expensive everyday lifestyle implementations that may add to the betterment basket🙏🏻.
Wow. Really enjoyed this exchange, great work.
the book is beyond brilliant
Interesting podcast! Curious if there is any research regarding what percentage of psychiatric patients have illnesses that are correctable physiological malfunctions versus a purely genetic presentation of illness.
Why are Spotify episodes way shorter than TH-cam ones?
Peter, where did you buy that blue t-shirt?
Great Great video as usual.. Thanks peter for your amazing effort to bring this knowledge to us..
Am ordering Projections today. Does anyone else hear Sam Harris’s voice and cadence throughout the interview?
Most people that think before they speak sound mildly sedated lol. The problem is that you don't find that quality on many. Myself included 😂
Dr. Attia, would you consider interviewing Dr. Ted Carrick?
Does anyone know the book Dr. Attia is referencing regarding hypomania as an evolutionary construct? I believe he said the Psychiatrist is or was from Johns Hopkins.
Likely referencing Kay Redfield Jamison if JHU and bipolar dx. Not sure if she's published extensively on evolutionary psychology but she's pretty big in the field.
🕊
Re: the genetic component of mental disorders.
It's 2022. I think it's about time to start considering in utero factors as separate from "genetics".
Just because monozygotic twins raised apart share a lot of diagnoses does not mean that the component to the disorder is predominantly genetic.
Stable mothers in ideal environments don't give their children up for adoption. The mother's stress/hormonal levels, whether the birth was traumatic, the neglect or lack of bonding post partum, etc - these are all factors that contribute to development significantly, and it is reductionistic to not consider them when discussing the root of mental disorders / adaptation variance.
Very interesting episode! Ketogenic Diet seems to help to sustain the "energy issues" with Bipolar disorder, according to studies the shifting in states might be related to impaired glucose "burning" / insulin resistance, due to genetic components that results in mitochondria dysfunction.
This resonated well with my own experience having Bipolar II and feeling better on Keto:
th-cam.com/video/x51HuJq0YCw/w-d-xo.html
Dude needs a haircut