Calcium & Vitamin D Intake in Adults with CKD - Prof. Marc Vervloet, Prof. Pieter Evenepoel

Prof. Marc Vervloet and Prof. Pieter Evenepoel present their recommendations on calcium intake in adults with chronic kidney disease (CKD), which are part of a recent European consensus statement that has been published in NDT. This consensus statement has been picked by MARKUS @ HOMe editors as “NDT's Paper of the Month” as part of our cooperation with NDT - Nephrology, Dialysis, Transplantation, the official journal of the European Renal Association.
Additionally, recommendations on vitamin D supplementation and therapy in adult patients with CKD are discussed.
Dr. Pieter Evenepoel is Associate Professor at the Faculty of Medicine and Adjunct Head of Nephrology at the University Hospital (UZ) of the Catholic University of Leuven in Belgium.
Dr. Marc Vervloet is Professor of Nephrology at Radboud University Medical Center at Radboud University and Head of the Department of Nephrology at Radboudumc in Nijmegen.
Both a globally leading researchers in the field of CKD-MBD.
The interview was recorded on March 21st, 2024.
Moderators: Prof. Dr. Daniel Cejka (Linz, Austria), Prof. Dr. Andreas Kronbichler (Innsbruck, Austria) and Prof. Dr. Gunnar Heine (Frankfurt, Germany).
Articles discussed:
Recommended calcium intake in adults and children with chronic kidney disease-a European consensus statement.
Evenepoel P, Jørgensen HS, Bover J, Davenport A, Bacchetta J, Haarhaus M, Hansen D, Gracia-Iguacel C, Ketteler M, McAlister L, White E, Mazzaferro S, Vervloet M, Shroff R
Nephrol Dial Transplant 2024
doi: 10.1093/ndt/gfad185
Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial.
Hahn J, Cook NR, Alexander EK, Friedman S, Walter J, Bubes V, Kotler G, Lee IM, Manson JE, Costenbader KH
BMJ 2022
doi: 10.1136/bmj-2021-066452
Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults.
LeBoff MS, Chou SH, Ratliff KA, Cook NR, Khurana B, Kim E, Cawthon PM, Bauer DC, Black D, Gallagher JC, Lee IM, Buring JE, Manson JE
N Engl J Med 2022
doi: 10.1056/NEJMoa2202106
Severe Hypocalcemia With Denosumab Among Older Female Dialysis-Dependent Patients.
Bird ST, Smith ER, Gelperin K, Jung TH, Thompson A, Kambhampati R, Lyu H, Zhao H, Zhao Y, Zhu Y, Easley O, Niak A, Wernecke M, Chillarige Y, Zemskova M, Kelman JA, Graham DJ
JAMA 2024
doi: 10.1001/jama.2023.28239
Vitamin D Deficiency Increases Mortality Risk in the UK Biobank : A Nonlinear Mendelian Randomization Study.
Sutherland JP, Zhou A, Hyppönen E
Ann Intern Med 2022
doi: 10.7326/M21-3324

[@abdelhamed012]

Future of long acting VitD analog for hyperpara thyroid

[@abdelhamed012]

Dialysate calcium recommended for patient on calcimimetics and not on calcimimetics 1.25 or 1.5 or 1.75 mmol

[@CaptainSteve777]

How can you discuss balancing blood vs bone calcium without emphasizing the function of vitamin K2?