All about Trulicity, Ozempic, Victoza, Bydureon, and others. An Intro to GLP1s

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  • เผยแพร่เมื่อ 27 ก.ย. 2024
  • Ever wonder about medicines like Trulicity, Ozempic, or Victoza? These diabetes medications all work in a similar way in the management of Type 2 Diabetes and improving A1c. In this video, I discuss the natural role of GLP-1 in managing blood glucose, how these medications fit into that role, what the benefits are, and what the side effects are.
    A couple corrections to the video:
    At 1:52, I misspoke and said "glycogen" instead of "glucagon"
    At 2:33, I accidentally said "insulin" instead of "intestine".
    Sorry about any confusion.
    As promised in the video, here are links to relevant studies on the cardiovascular safety/potential benefits of these medications:
    Adlyxin: www.nejm.org/d...
    Bydureon: www.nejm.org/d...
    Victoza: www.nejm.org/d...
    Trulicity: www.thelancet....
    Ozempic: www.nejm.org/d...
    Rybelsus: www.nejm.org/d...

ความคิดเห็น • 237

  • @magil3112
    @magil3112 10 หลายเดือนก่อน +7

    In France, Ozempic and Trulucity cost 89€ for a months supply and covered 100 % by the Insurance if you’re a diabetic.

    • @DjeasyMuzikRyder
      @DjeasyMuzikRyder 10 หลายเดือนก่อน

      True and now trulicity is not available, it's getting very scares now I can't get in no pharmacy I have to ask my doctor to suggest me an alternative..sigh

  • @hollismallory2757
    @hollismallory2757 3 ปีที่แล้ว +31

    This guy is amazing at explaining things

  • @lynnehallier8859
    @lynnehallier8859 4 ปีที่แล้ว +15

    Since being diagnosed with type 2 diabetes 6 or 8 years ago, I have been using metformin, and totally unable to lose weight. Believe me, I tried every diet on the map and was unable to lose weight. I asked my doctor about Ozempic after hearing tremendous success of a co-worker. I just finished my fourth pen and have lost 15 pounds! My morning glucose has dropped by 40 or 50 points. Can’t wait till my upcoming appointment to see what happened to my last A1C of 6.3. Thank you for the video. I learned a lot, and was wondering about the cancer issue also.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว

      Thanks for sharing your experience! I'm glad you found the video helpful!

    • @walterjohnson5602
      @walterjohnson5602 ปีที่แล้ว +1

      Watch your creatinine, because I had to stop metformin a long time ago when it started to impair my kidney function, as measured by the Creatinine level. "A normal result is 0.7 to 1.3 mg/dL (61.9 to 114.9 µmol/L) for men and 0.6 to 1.1 mg/dL (53 to 97.2 µmol/L) for women. Women often have a lower creatinine level than men. This is because women often have less muscle mass than men. Creatinine level varies based on a person's size and muscle mass." By 2.0 you should be seeing a kidney specialist.

  • @daviddow8150
    @daviddow8150 ปีที่แล้ว +1

    I have just started trulicity. The one thing I notice most is a feeling of calm and well being

  • @AxelQC
    @AxelQC 4 ปีที่แล้ว +21

    Your videos are a perfect balance of entertaining, understandable, and informative.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +4

      Thank you! Honestly, this is exactly what I'm going for so it means a lot that it's coming across that way.

  • @phanet4lyfe
    @phanet4lyfe 3 ปีที่แล้ว +4

    Your channel is wonderful! I'm an ambulatory care pharmacist working with patients with diabetes and these videos are so useful! I love the "possibilities and not promises" for adverse effects.

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว

      Thanks for your feedback! That really means a lot to me and I'm glad you've found them helpful.

    • @suzannemendez520
      @suzannemendez520 9 หลายเดือนก่อน

      I’ve been on Victoza for three months and I have only lost 3 pounds when will I lose more weight I can’t wait I just want to lose 20 pounds

  • @NewPOV
    @NewPOV 4 ปีที่แล้ว +15

    Excellent video! Learned a lot, and I thought I already knew a lot. 😎

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      Thanks Jon! I’m glad you found it helpful. Lots more on the way.

    • @brigittegilroy2882
      @brigittegilroy2882 3 ปีที่แล้ว +1

      @@sugarhighchannel ]++

    • @patriciaabidi4481
      @patriciaabidi4481 3 ปีที่แล้ว +1

      @@sugarhighchannel hi, do you have Diabetes?

  • @pcnav8036
    @pcnav8036 3 ปีที่แล้ว +2

    Very good video. The reason I looked up your video was because of the cancer warning. You made it easy to understand the risk.

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว

      I'm so glad you found it helpful. Thanks for commenting.

  • @gregpavlovich7761
    @gregpavlovich7761 ปีที่แล้ว +1

    Thanks for your insight. I have been on Trulicity for around 6 months and it has been a real game changer for my type 2 diabetes. My sugar levels have gone from through the roof high to near enough to perfect. It is super easy to use every Sunday night. I had some very mild side effects the first time I used it but nothing worth noting. Most times I inject I barely feel the shot and have to check it actually worked 😅 I can highly recommend. Thanks Greg

  • @vicndav55
    @vicndav55 ปีที่แล้ว

    Thank you so much on the very simple and clear explanation. I feel so much better about what my doctor is trying to do to help me. I was very resistant to trying these meds but now you have reduced my fear and anxiety about them and I am looking forward to trying them.

  • @irmamckinney6677
    @irmamckinney6677 3 ปีที่แล้ว +7

    I've been taking victoza for about five months now and I've lost 45 lbs and feel AMAZING!! Yessss, it does make your stomach feel upset when you over eat so I'm eating about 1,000 calories a day and once in a while I get headaches but other than that this is an amazing drug. I did stop taking it for about a month cuz of the high cost and I did notice that I didn't lose any weight but I didn't gain any either so I guess that wasn't so bad. I still have another 30 lbs more to lose and I'll be happy but I truly recommend using this drug for weight loss!!

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      Glad it's going so well for you. Thanks for sharing your experiences. Wish it was cheaper...

    • @frankieandkristentravel
      @frankieandkristentravel ปีที่แล้ว

      I was just put on victoza I'm hoping it works for me like that. I know it has curved my hunger by 90%

  • @liewvuikong9131
    @liewvuikong9131 3 ปีที่แล้ว +1

    i love all your videos because of the honesty of what you said. And keeps it that way.

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว

      Thank you so much for your feedback. I'm glad you've enjoyed the videos.

  • @madelinehall8944
    @madelinehall8944 ปีที่แล้ว

    I was prescribed Trulicity this week. The cost to me was a shock. I didn't get it. I came home, got online and researched coupons and help. I found Lily offers assistance to low income patients. I couldn't afford to come off metformin. I hope Lily helps me. Thank you for the informative videos. Cost is a bigger deal

  • @djb6313
    @djb6313 3 ปีที่แล้ว +1

    Just about to start a glp-1 treatment and this video helped me understand how it works and feel better about taking it.

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว

      Glad you found it helpful! Thanks so much for your comment.

    • @djb6313
      @djb6313 3 ปีที่แล้ว

      @@sugarhighchannel btw...blood sugar has been perfect since starting and have lost 22lbs . No major side effects other than slight nausea and constipation at the beginning.

  • @antoinetteblair4
    @antoinetteblair4 3 ปีที่แล้ว +2

    EXCELLENT video as usual ❤️

  • @MrPenguinLife
    @MrPenguinLife 3 ปีที่แล้ว +1

    Thanks for the video, and to answer your question yes I have been on Trulicity for about 2 years

  • @yahyamohammedpatel1432
    @yahyamohammedpatel1432 4 ปีที่แล้ว +3

    Just Started taking Trulicity, had my dose on Saturday. Its Thursday today, I feel nauseous and have gone completely off my food, but on the plus side, my sugar levels have come right down to normal. Thank God for the NHS here in the UK means that I do not have to pay for my medication.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว

      Glad you're seeing some glucose improvements! Here's hoping that the nausea fades quickly. Thanks for sharing your experiences!

    • @carlmilton1
      @carlmilton1 4 ปีที่แล้ว +1

      How are you feeling after 4 weeks? I have just taken my first shot today. Hope you are feeling a bit better.

    • @yahyamohammedpatel1432
      @yahyamohammedpatel1432 4 ปีที่แล้ว +1

      @@carlmilton1After 2 weeks I stopped. Had my problems with side effects, ie constipation, unable to eat anything, and nausea. But that's just me. May be it will work for you.

  • @hildaperry4366
    @hildaperry4366 2 ปีที่แล้ว +1

    You are amazing you have been very helpful and had the gastro bypass still struggling with my weight I have started with those epic it stop the craving progress and work

  • @yolandasalone7949
    @yolandasalone7949 4 ปีที่แล้ว +3

    Everyone talks about the side effects. Of you being nausea? But no one talks about the side effects of being constipated. I just started. Trulicity and I have constipation. I've taken stool softeners. And doctor prescribe medication for constipation and I still haven't went I do not like this feeling. Thanks for the video.

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      Yup, constipation can happen too. Glad you enjoyed the video

  • @JaeStories87
    @JaeStories87 3 ปีที่แล้ว +4

    You've been incredibly helpful to me with my diagnosis last month, putting my mind at ease with these "scary" shots that aren't so scary anymore. I hope you eventually do a deep dive into Victoza, as that's the pen my doctor prescribed me. Can't wait for the next video (hopefully soon)!

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว

      Your feedback really means a lot to me. Thank you for your kind words and I'm glad you've found it helpful!

  • @magehistorian
    @magehistorian 3 ปีที่แล้ว +1

    I would like you to know that your explanation of how glp-1 meds worked saved me a trip to the urgent care. I freaked out after I took a dose and thought I had been given the wrong pen.
    Your video on how they work helped me realize that I had time to put in a phone call to my doctor (she moved me to the full dose) and get and explanation.
    Thank you for saving me an unneccessary bill!

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +2

      That's great! I'm glad you found it helpful and I appreciate your kind feedback.

  • @LaraHarker91
    @LaraHarker91 ปีที่แล้ว +1

    This is my 4th day on victoza and i have been having panic attacks and insomnia after application (I apply it at night). I just hope this awful fear to medications goes away😢

    • @freshbme2
      @freshbme2 ปีที่แล้ว

      I dont no who you are, but my mom is on trulicity and is having the same issues. Nausea, heartburn, and insomnia...

  • @punkin60
    @punkin60 2 ปีที่แล้ว

    Ashamed to say I have used 80% of these meds with little or no success. Metformin for years but I had horrid episodes of lactic acidosis recently. Had RNY surgery and lost 100# and kept it off for 12+ years but BG shot up again. I have found success with Ozempic and a low carb diet. The combination is amazing.

  • @gary3696
    @gary3696 2 ปีที่แล้ว

    I was started on Trulicity a little over a month ago, since then my FBS has returned to almost normal, can't weight (pun) to see what my A1c is later this month, I have had a gastric sleeve 6 yrs ago, and still only wound up losing an average of 20% of my excess weight. Since Truliciety I've lost another 30lbs!!!, This has been a wonder drug for me, I'm a disabled vet and have used a cane for past 10 years, there are times where my pain has decreased to the point that I don't need it around the house. BUT: This morning I woke up with a swollen lymph node in my neck, it's tender to palpation and so called my Doc, we'll see what he says.

  • @carlmilton1
    @carlmilton1 4 ปีที่แล้ว +2

    Great video. Just had my first shot of Trulicity. Trying to learn what I can as I have just been diagnosed with type 2.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      carlmilton1 Thanks for your feedback! Hope the Trulicity helps you and best wishes as you nail diabetes!

  • @slaveteri
    @slaveteri 4 ปีที่แล้ว +1

    i'm a Bydureon user and i LOVE it. i started on just metformin and had gotten my A1c down to about 6.0, then it started creeping up again, even though my blood sugars weren't really reflecting that. When it got to 7.0 again, my NP and i decided to add the Bydureon. i'm back down to 6.3 after 6 months. There is NO WAY i could afford this, even with my insurance! But my NP gave me a card and Astra Zeneca basically pays for their own med for me to take it. $800+/mo is definitely out of my price range!
    i've lost a little weight, not a lot, but i also have other endocrine issues that affect that. i definitely feel full after eating now, which isn't something i was experiencing before. i'm not a super heavy woman starting with 240 at my highest, before being diagnosed, now hanging around 200 now, but all that weight is in my belly. my legs and arms are super skinny. Slowly losing weight still, but people keep telling me that is the healthy way to go. :-)
    When i was younger (i'm in my 50s now), i was maybe 100lbs soaking wet. Never would have guessed i'd become diabetic. Mom is Type 1, diagnosed when she was in her 40s and Dad was just diagnosed Type 2 a couple of years ago in his 70s. But i never really showed any symptoms, until i started losing feeling in my toes! Got diagnosed ASAP after that. And that's my experience! Looking forward to they Bydureon specific video!

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      Glad to hear you're doing so much better! Thanks for sharing your experiences.

  • @christhianeribeiro388
    @christhianeribeiro388 3 ปีที่แล้ว +1

    What a great video. Thank you!

  • @raelynnkijkowski9549
    @raelynnkijkowski9549 2 ปีที่แล้ว +2

    I tried ozempic and was amazing for my blood sugars but i had severe constipation like no poops without a laxative. Im off ozempic and everything is back to normal there. But the medication is so good for my blood sugars I wonder if I should try trulicity as it is duraglutide rather than semaglutide but still a GLP1 or will I have the same side effect? and maybe I just wont know unless is give trulicity a try. I'm so thankful because the healthcare in my province covers medication along with insurance.

  • @maximilian9295
    @maximilian9295 2 ปีที่แล้ว +1

    :/ pharmacy said Ozempic was 1200 a month, and that was with insurance paying a portion! Crazy

  • @danpadilla4543
    @danpadilla4543 3 ปีที่แล้ว +4

    Thank you for the great video… I’m currently on oral diabetic meds (glipizide and janumet), if I should try any of these GLP1s, will I still need to take any of the oral meds? Thank you in advance. 😊

  • @PatrickHunlock
    @PatrickHunlock 3 ปีที่แล้ว +1

    Hi! Love the channel! Please do a video on Victoza. I'm on this and would love to get a a real deep dive into what its actually helping (and maybe hurting -- besides my pocketbook)!

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      You bet. I’ve been waiting on a resupply of Victoza samples so I could use them for a video. They just got delivered earlier this week so I’ll get that made ASAP.

  • @sikreyto
    @sikreyto 3 ปีที่แล้ว

    very informative. excellent job

  • @carlosusepulveda5492
    @carlosusepulveda5492 3 ปีที่แล้ว +3

    I can use Januvia and Ozempic together?

  • @prasadhonnavara875
    @prasadhonnavara875 3 ปีที่แล้ว

    Good presentation.

  • @jonpatterson5668
    @jonpatterson5668 4 ปีที่แล้ว +1

    I just picked up my pen today. The Bydureon pen

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      Great! I’m actually working on a video specifically about Bydureon. Should be up in a few days. 👍

    • @sibertater
      @sibertater 4 ปีที่แล้ว

      I’ve been on it for 10 weeks and I am switching to Ozempic because of the knots at the injection sites. I have a bump for every injection. It’s weird.

  • @ToddHarrisonDavis
    @ToddHarrisonDavis ปีที่แล้ว +2

    You asked for stories and feedback. I've had type-2 diabetes for over a decade now. Metformin works for me to some degree, but it is inconsistent, didn't manage my A1C well, and it's a lot of pills to take, so when I learned about Trulicity (T), I asked my doctor about it right away. The experience with T was great. I'm a huge baby when it comes to needles, but as you mentioned in another video, the injection system T uses is great, and most of the time, I don't feel the injection at all. I love it, it works great, and now I can inject myself once a week rather than much Metformin all day every day. I did have some minor side effects from Trulicity, such as occasional nausea and other intestinal hijinx, but for the most part, it was fine. I did lose some weight, not much, but the better part was that I was able to keep my existing weight pretty steady regardless of what I ate or how much exercise I got.
    Things changed in the past year. The "Ozempic diet craze" started, and all of a sudden, the drugs I could previously buy were no longer available, because people were buying GLP-1's in bulk hoping to fit into their bikinis next summer, while folks like myself who actually need the stuff to live were facing "out of stock" issues with our medications. At one point, after searching for T for a few weeks and being told it was going to be a month or more until more stock came in, my doctor chose to switch me over to Mounjaro (M). The stock of that was low as well, but they had plenty of the highest dose (16mg I believe), so that's what I took.
    Things went well at first, it seemed to be working. I started to notice that I was burping however, constantly, as in all day, every day. My food portions slowly got smaller and smaller to the point where just a few bites of food seemed to fill me up. Then the nausea started to set in. At first I threw up once a week or so. Then twice a week. A few months in, I had a really bad day. I started to throw up and simply could not stop. I thought my shoes were going to come out of my mouth. After that episode, my eating stopped, almost entirely. I could barely drink water and even that made me nauseated after a sip or two. I basically stopped eating after that. If I tried to eat anything more than a single, tiny bite, it just came back up, and I was nauseated all day and night. I wasn't eating so I started to lose weight at a rapid pace. I ended up losing over 30 lbs in the span of three weeks. I had no energy, I was dizzy, weak, I could not concentrate, and in the third week, I started to experience severe muscle cramps in my calves and was having trouble walking. We honestly thought I was going to die. Since nothing was going down (and I should mention I also have Crohn's, so gastrointestinal problems are common for me anyway. I should also mention that I had ROUX-N-Y stomach surgery about 20 years ago) we just naturally assumed I had a blockage in my intestines, so I got several scans plus an endoscopy, and... nothing. No blockage.
    To make a long story short, the M had slowed my digestion down so very much that it had almost stopped entirely. I wasn't hungry and couldn't eat because my stomach was constantly full. Whatever I ate just "sat there" or came back up. I was taken off the M and it took several weeks before I was back to normal again. If it had continued, even a while longer, severe problems would have formed. I'm lucky it reversed itself.
    After a few weeks, I went back on Trulicity. So far, while I again have some nausea and some digestion issues, it is for the most part doing okay. I don't know if I have a "moral to the story" other than to be aware of what those side effects are, and to be super clear with your doctor about what you are experiencing. You shouldn't be sick all day, every day, and if you are, that's a problem, so go see your doctor. And be careful about switching suppliers. Not all GLP-1's are the same, and your ability to tolerate one might not translate to another, so start slow and watch your body carefully.
    These GLP-1's are the best stuff we've got right now to help control diabetes. I really, really hope that somehow they encourage people who are using it as a diet fad to look elsewhere, as they are not only taking medicine away from people who need it to live, but also, you will have to take it for life if you want to maintain your weight. The moment you go off it, your digestive system will start to function normally again, your appetite will come back, and your body may not know how to handle it. Just be aware that you are "using a trick" to fool your body, and that's not how it's supposed to work, so be careful. For the cost of Ozempic you can afford a good trainer. Do that instead. :)

  • @anitatillotson5138
    @anitatillotson5138 4 ปีที่แล้ว +3

    I just started Victoza. It’s been very helpful with my blood sugar levels. However, I do feel nauseous and get headaches. I don’t want to stop using it because I like the numbers I have been seeing. I’m hoping those side effect will go away.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      Anita Tillotson Thats often how people describe the side effects. They can be annoying, but a lot of people are willing to deal with it because they feel the good outweighs the bad. For some people it’s too much. Hang in there; I’m glad you’re getting good results.

    • @lollybabe08
      @lollybabe08 ปีที่แล้ว

      hope it has improve for you. No side effects for me!

  • @angelalondono9559
    @angelalondono9559 2 ปีที่แล้ว +3

    Thank you so much, I enjoy the way how you explain everything. By the way I am human not a rat, haha, so I am safe.

  • @lazmotron
    @lazmotron 3 ปีที่แล้ว

    Great Channel!

  • @carinasoria8445
    @carinasoria8445 3 ปีที่แล้ว

    Thank you so much

  • @rambskin
    @rambskin 4 ปีที่แล้ว +4

    trulicity makes mre dehydrated, severely. So severely I passed out while driving and crashed my vehicle on Valintine's day 2019. I have stopped taking it and dehydration decereased.

    • @TebTengri
      @TebTengri 3 ปีที่แล้ว +1

      Kind of the bad thing of those once weekly meds is if the side effects hit you hard you're stuck feeling like crap for multiple days.

  • @stephengoetsch349
    @stephengoetsch349 ปีที่แล้ว

    I used Trulicity for four years until 2020, when I switched back to a low dose of metformin. My objective was to lower my medication costs upon retirement and combined it with a more rigorous avoidance of carbs in my diet to perhaps get to not using any diabetes medications at all. I was unable to reach the goal of no metformin, and my a1c and weight began to creep up. So, after more than two years on metformin, I have begun transitioning to Ozembic, which may not have been available or as well known as Trulicity when I first started Trulicity. My most recent a1c was 6.5%, but on Trulicity I was actually at 5.6% at one point. I think the GLP-1 agonists are miraculous.
    I never felt nauseous with Trulicity, but I am having a few problems with Ozembic, but so far these are minor.

  • @tiernyt2051
    @tiernyt2051 3 ปีที่แล้ว +1

    THANK YOU,, so much your awesome!! I JUST started taking the Ozempic once a week. I do have bloating a little dizziness, other then that it's been tolerable. My question is "Can I do anything about the bloating? Like ASAP?

  • @cledusneighbor2630
    @cledusneighbor2630 3 ปีที่แล้ว +1

    do i need to refrigerate victoza

  • @carriebill2262
    @carriebill2262 2 ปีที่แล้ว +1

    I am about to finish up my first month of Victoza and haven’t seen much weight loss. I noticed I am feeling more full when I eat and not eating as much. I have felt headache and constipation. I was on metformin for 3 months and lost about 22 lbs. I have dropped my A1C from 8.4 to 6.9 or 6.1 on metformin. I do feel more confident about myself now then before.

  • @paulaelliott65
    @paulaelliott65 2 ปีที่แล้ว +1

    Anyone have a symptom of tastes being different? Four not tasting the same or some just really bland?

    • @tbeckermom
      @tbeckermom 6 หลายเดือนก่อน

      Yes I did. I couldn't figure out why everything I used to love to eat didn't even taste good to me either.

  • @ahmedthamir9531
    @ahmedthamir9531 ปีที่แล้ว

    I have one big problem with insulin and all other "secretogogues"... type 2 DM is supposed to be a problem with too much insulin that the body doesn't respond to, how more insulin is going to help?!!

  • @sarahkaddoura398
    @sarahkaddoura398 3 ปีที่แล้ว +1

    If we still get strong reflux side effects after two months ? What should we do ? Should we stop ??? Am talking about Ozempic

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      The best course is to consult your healthcare provider for direction. Sometimes reducing the dose can help, sometimes using heartburn or anti-nausea medication can help. But there are other circumstances that might prompt your provider to direct you to stop it altogether. Only he/she knows your specific situation and can give you the best advice.

  • @TebTengri
    @TebTengri 3 ปีที่แล้ว +2

    Even in Mexico trulicity and victoza are $50-150(US dollars) a month.

    • @AzKat69
      @AzKat69 3 ปีที่แล้ว +1

      in europe 1 ozembic pen is 200 euros (~250$), no idea how they got to $800 in the US

    • @terry2346
      @terry2346 3 ปีที่แล้ว +1

      @@AzKat69 Because the drug companies know they can get away with it in the US. If Medicare was able to negotiate drug costs, which they are not allowed to do by law, then the costs would be more in line with the rest of the world.

  • @marjoriebrindley5766
    @marjoriebrindley5766 3 ปีที่แล้ว +2

    Is Ozempic better than trulicity?

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว

      Depends on what you mean by "better". In ta direct comparison clinical trial, Ozempic outperformed Trulicity for both A1c reduction and weight reduction. But that was before the maximum dose of Trulicity was increased to 4.5 mg/day. The new maximum dose of Trulicity is more comparable to the maximum dose of Ozempic, but that's based on results of different clinical trials, not a head-to-head comparison. Cost-wise, Ozempic is a bit more expensive, but it's not a huge difference.

  • @brendaallen8609
    @brendaallen8609 3 ปีที่แล้ว +2

    Which one do you like the best for weight loss

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      Ozempic and the recently-approved higher dose (4.5 mg) of Trulicity have been shown to offer the most weight loss. I've had a lot of good luck with Ozempic in my patients, but haven't yet had the opportunity to try the higher doses of Trulicity since they JUST got approved a couple weeks ago. But this clinical trial results look promising.

  • @SouthofIllusion
    @SouthofIllusion 10 หลายเดือนก่อน

    Awesome video! I read an interesting study about the efficacy of GLP-1RA in postprandial hypoglycemia patients after gastric bypass. The study mentioned how it seems counterintuitive, but this particular class of medication tends to work extremely well for these patients in controlling blood sugar levels. I was wondering if that might have something to do with the side effect that GLP-1s often have of delayed gastric emptying, or if there's some other reason why they're effective for patients with reactive hypoglycemia. My understanding is that many of these patients have increased beta cell mass in their pancreas, so it really does seem counterintuitive to add a drug which releases more insulin. Do you have any thoughts on this? I'd really like to know your take on it!

  • @djmd808
    @djmd808 4 ปีที่แล้ว +2

    While watching this, my TV was on and muted and an Ozempic commercial aired - touting it's affordability at the end with all the fine print flashing by... what do you think the future holds for GLP1s? Do you think us commoners will ever be able to afford it without selling our children?

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +3

      Yeah, the affordability can be a challenge, depending on your insurance. I have some patients who's insurance plan will never pay for these in a million years and some who get it for a $3 co-pay. And then anywhere in between. The affordability that the commercials are usually referring to have to do with co-pay assistance cards that take the price down to either free or $25, assuming your insurance will at least cover part of it. Once medications go generic they usually become much more affordable, but the manufacturing of meds like these is MUCH more complicated than making a simple generic tablet or capsule. So the price will definitely go down with time, but no one really knows by how much.

    • @lynnehallier8859
      @lynnehallier8859 4 ปีที่แล้ว

      There is a coupon available on the internet. Possible this might help?

    • @user-el6wg1xe9e
      @user-el6wg1xe9e 4 ปีที่แล้ว +2

      @@lynnehallier8859medicare or medicare advantage I do not think you can use coupons or discounts

  • @Josh-bz7kf
    @Josh-bz7kf 2 ปีที่แล้ว +1

    Can you use it for weight loss even if you don't have diabetes?

    • @webdroid7938
      @webdroid7938 2 ปีที่แล้ว

      Yes you can. Expect lots of side effects that will disappear with time. Talk with your doctor.

  • @caro133244
    @caro133244 4 ปีที่แล้ว +1

    Buenas tardes. Quiero sugerirte si es posible que los video tenga substitución en español. Muchas gracias

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว

      Hola y buenas tardes. Yo planeo agregar subtítulos en español y en ingles a mis videos. Espero que puedan ayudarte!

  • @bookfairee
    @bookfairee 3 ปีที่แล้ว +1

    My AC1 is 5.6 I’m starting to have higher blood pressure. Which I never had. Also high colestral again never had weight has creeped up in the past 3 months. I take thyroid meds. Would ozempic be something to speak to dr about.

  • @Bluewillowskys68
    @Bluewillowskys68 3 ปีที่แล้ว

    Never heard of byetta ever....very strange when the others run commercials constantly....returning to the video .....more comments later

  • @JennyNguyen0512
    @JennyNguyen0512 4 ปีที่แล้ว +2

    Can you do a video on trulicity and semaglutide (injectable and tablets) and possibly compare them? I’m a pharmacy student. I come across several patients who were prescribed ozempic. Almost all of them experience SEs. Some doctor just told their patients to D/C ozempic and switch back to their old diabetes regimen if they don’t tolerate ozempic. Ozempic is such a great drug but not many doctors are able to keep their patients on it. How do u instruct ur patients to take ozempic to minimize the side effects? I know some doctor start their patients on 5 clicks and then slowly increase to 0.25mg and eventually to 0.5mg or 1mg.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      Sorry for the late reply; I somehow missed this comment! I recently posted a video on Trulicity that compared some of the more common side effects to the others in this class- I think that might answer some of these questions. I'll continue to do that for upcoming videos on each GLP-1 med. I've used the approach that you mentioned, recommending lower-than-marked doses by counting clicks for both Victoza and Ozempic. Sometimes we get caught into thinking that we "must" use the marked doses, but there's a whole lot of click in between that 0 and 0.25mg marking that people can count off if they need a more gradual dose increase plan.

    • @sbherring3223
      @sbherring3223 3 ปีที่แล้ว

      @@sugarhighchannel I just started on Victoza and I am trying just a few clicks to adjust to it . Tried Trulicity a while back and had an awful experience which lasted for 5 1/2 days...then a day and half good then the cycle repeated when I did the next injections. My question is if I stay on the lesser number of clicks, the vial will last for more than 30 days but the tube says to discard after 30 days. I think it will be hard to throw out this $800 Rx. What do you think about taking it beyond that 30 day period? Thanks heaps!

  • @janelab1015
    @janelab1015 4 หลายเดือนก่อน

    Trulicity is not available in Ohio
    What is the best one to switch to?

  • @kraeergroup5145
    @kraeergroup5145 10 หลายเดือนก่อน

    I have had diverticulosis and actually part of my intestines removed and a colostomy bag this was at least 10 years ago. I had the colostomy for about 7 weeks then went through successfull reattach, so thankfully no more bag. Is it safe for
    Me to be on the type of medication as I am over Wyandotte stage 2 diabetic

  • @yendepaz1530
    @yendepaz1530 ปีที่แล้ว

    I love trulicity i am on my 3rd month and so far so good

  • @Morganrcb1
    @Morganrcb1 3 ปีที่แล้ว +1

    I have more questions for LADA 1.5 patients with insulin resistance on a pump. Will cause hypoglycemia? I also have NASH, concerned about liver dumping.

    • @lollybabe08
      @lollybabe08 ปีที่แล้ว

      There are some LADA on GLP-1 agonist with success. but u need guidance of endocrinologist. Study noticed lower insulin requirements

  • @elsacavazos5981
    @elsacavazos5981 ปีที่แล้ว

    How about the effects on kidneys?

  • @randyware4365
    @randyware4365 4 ปีที่แล้ว +3

    Hello I have been a type 2 going on 18 years have been on Lantus for 17 I’m controlled with 25 units a night and 5 to 8 of humalog before meal as needed. Do you think I would benefit from 1 of the GLP’1s.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +2

      Hey Randy, it’s possible. Adding a GLP1 may possibly allow you to do without the Humalog since it’s a low dose.

  • @susand4230
    @susand4230 2 ปีที่แล้ว

    What about the risk of Fournier’s gangrene?

  • @nbmeg6228
    @nbmeg6228 2 ปีที่แล้ว

    My doctor told me that Trulicity will help with my Non Alcoholic fatty liver disease

  • @TheRebelHawk
    @TheRebelHawk 4 ปีที่แล้ว +1

    What about Symlin?

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว

      TheRebelHawk Symlin has a similar function, but is a different hormone and a different medication class. It’s only used in conjunction with insulin, but it’s not a bad medication when used for an appropriate patient.

  • @mibo4130
    @mibo4130 4 ปีที่แล้ว +1

    Greetings from Germany

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      Herzlich willkommen! Ich bin froh, dich hier zu haben.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      That was Google translate. I have no idea if that came through correctly. But hello! Happy to have you here.

    • @mibo4130
      @mibo4130 4 ปีที่แล้ว +1

      @@sugarhighchannel perfectly right :) I'm happy that you give so much effort in curing humans.

  • @pamelaferguson7766
    @pamelaferguson7766 2 ปีที่แล้ว

    I just asked my Dr. About trying Ozimpic. I've been on victoza for a few years now, and believe it's become ineffective. He gave me a couple of examples of Ozempic to take the place of the Victoza and the nurse told me she'd they more from the medical salesman. Are requesting samples of medicines from salespeople a normal practice?

  • @Brian.8272
    @Brian.8272 3 ปีที่แล้ว

    i had a heart attack in January, I have a1c of 5.5 and glucose of 114. I'm 5'7" and 52 years old 186 pounds, would a doctor prescribe me glp-1 medication?

  • @kathycheesman2877
    @kathycheesman2877 ปีที่แล้ว

    Can you tell me in your opinion what is the best oral medication for diabetes to take with ozempic

  • @awwkib
    @awwkib 3 ปีที่แล้ว +1

    Hi, I wanted to know which one is better in reducing weight? Victoza or Ozempic? I'm 120kg (6ft 4" height & 38yrs old). Also what about the performance of the oral one Rybelsus? Lastly, have you heard about Saxenda? Is that also a GLP-1 medication?

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      They actually compared to Victoza and Ozempic directly in a clinical trial and Ozempic brought about more weight reduction. Saxenda is a higher dose of Victoza intended for weight reduction in non-diabetic people.

    • @awwkib
      @awwkib 3 ปีที่แล้ว

      @@sugarhighchannel thanks for replying... can non-diabetic use Victoza? For how long should they use? 3 months should suffice and then take a break for how many months before starting another course of 3 months?

  • @CSimi115
    @CSimi115 3 ปีที่แล้ว +1

    Which one of these medications would you suggest specifically for weight loss? Saxenda was recommended but it’s not covered at all by my insurance.

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      Saxenda is just high dose Victoza, so one could theoretically use Victoza for the same effect, but to would require multiple injections. BTW- a full review on Victoza is uploading as I type this. :) Ozempic is also currently in clinical trials for the purpose of weight loss in non-diabetics (although when/if it gets approved by the FDA it will have a different name in the same way that Victoza and Saxenda have different names).

    • @daleval2182
      @daleval2182 3 ปีที่แล้ว

      @@sugarhighchannel now that helped, i appreciate the way you de code the games drug companies play to market and mix match names, when 3 or 4 names are the same GLP 1,Thank you

  • @kevingose8940
    @kevingose8940 4 ปีที่แล้ว +1

    Very informative video. Reminded me of Crashcourse in your deliver and editing. T2 for 8 years, started Ozempic 5m ago 0.5 weekly dose, also Farxiga. (Previous meds: couldn’t tolerate Metformin, switched off Januvia for Ozempic) family history both parents and both grandparent sets T2 & 1 sibling T2
    About once a month, I get severe burps. (I apologize for the next description) The burps taste yeasty like beer burps when you chug a beer. Sometimes this is accompanied by diarrhea, nausea, or vomiting.
    I am not sure if this is the new normal, or if others experience this also. Is there something I am eating or can avoid eating? Is there something I missed in the paperwork? It is sporadic enough that I forget about it until it happens again the next month.
    What “troubleshooting” should I do before my next Dr. visit to help her have more information to work with? Besides this monthly day or two, I have had good results with daily sugar and weight loss.

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +2

      Hi Kevin, thanks for your comment. In addition to all of the other gastrointestinal side effects, Ozempic can cause, or worsen, acid reflux. That could be a likely culprit for what you're describing. Fried/fatty foods, spicy foods, and alcohol often contribute to worsening acid reflux as well, but in can also be a rather individual thing. As fas as troubleshooting, smaller, more frequent meals are usually recommended in people with reflux. I also would try to identify triggering foods (perhaps keep a food diary on the days it happens) to see if you can pinpoint anything leading to the symptoms and if simple avoidance of triggering foods don't provide relief, plan on discussing it at that upcoming Dr visit to see if he/she thinks any treatment would be appropriate. Glad you're getting good glucose results with it and I appreciate your feedback!

  • @TheMrsJMay
    @TheMrsJMay 2 ปีที่แล้ว

    My doctor has changed me from Ozempic to Trulicity because my new insurance wanted me to try other forms of GLP1s. I have lost 15+ lbs with no annoying side effects on Ozempic. Do you suspect I’ll experience any side effects from switching to Trulicity? I have been off of Ozempic now for about 6-7 weeks because of the fight with insurance. Please advise. Thank you!!!

  • @humbypaul66
    @humbypaul66 3 ปีที่แล้ว

    how about gliclide

  • @vwziful
    @vwziful 3 ปีที่แล้ว

    how common is hypoglycemia with these?

  • @alessandrocarta852
    @alessandrocarta852 3 ปีที่แล้ว +1

    How long does it take for Trulicity 1,5 to take effect?
    this is my 5 week my glycemy is 150 in the morning without food

    • @AzKat69
      @AzKat69 3 ปีที่แล้ว

      check with your doctor

    • @cheryllittle7578
      @cheryllittle7578 3 ปีที่แล้ว

      Some ppl dont tespond to T ... talk to ur dr about aemaglutide more info on MPMD youtube on topic ,newer med reports inc in show notes as well.

    • @cheryllittle7578
      @cheryllittle7578 3 ปีที่แล้ว

      ...if ur doing 1.5 ya id seek out further info and go talk to dr fer sure.

  • @njcamocutie7085
    @njcamocutie7085 4 ปีที่แล้ว +1

    Thank you so much for all this info.I needed it.I take 32 iu of Basgalar insulin and my doc wants me to take this(victoza) to on top of that is this ok to take with insulin to? Im always so skeptical when taking meds(also on metformin 1000 daily)oh also have a fatty liver ( yeah ima mess i know)

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      NJ CAMOCUTIE - For sure! We use Victoza along with insulin all the time. Just make sure to check your glucose frequently since the Victoza will probably help your Basaglar to be even more effective. If you get low glucose readings, let your provider know. Sometimes people don’t need as much insulin anymore and we cut the dose back. 👍

    • @njcamocutie7085
      @njcamocutie7085 4 ปีที่แล้ว +1

      Yes thats exactly why im scared to start the treatment as he said a common thing is my sugars can go low thru the night amd that's terrifying as i do t know what will happen.I barely have my sugars in check on just the Bagsgalar,now o do t wamma worry about something else new.UGGG!!! I have totally changed my diet ,no whites ,soda junk etc.

    • @daleval2182
      @daleval2182 3 ปีที่แล้ว

      @@njcamocutie7085 I'm like, the thing that has helped me most, is under 20 carbs a day, keto food, and reducing calories, i may ask for this med too

  • @cledusneighbor2630
    @cledusneighbor2630 3 ปีที่แล้ว

    I just got a victoza pen, will my sexsenda needles work

  • @Muppetfanforevah
    @Muppetfanforevah 3 ปีที่แล้ว

    How does this drug affect my blood sugar while on a ketogenic diet?

    • @RoRo-nl2wy
      @RoRo-nl2wy 3 ปีที่แล้ว +1

      I have the same question?

  • @patrickhepburn7867
    @patrickhepburn7867 2 ปีที่แล้ว

    I have been using trulicity and less appatit and lost weight.

  • @evamaynard3021
    @evamaynard3021 4 ปีที่แล้ว +1

    Why am i just now seeing your videos!!! Yes!!!! Do you do any on pcos and endometriosis? Because I feel like those two are the evil step sisters of prediabetes, which I have, so im very interested in your thoughts

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว +1

      Thanks for your comment. I'm definitely planning on covering PCOS in future videos. It's completely tied into insulin resistance, including prediabetes.

  • @oscarm.4078
    @oscarm.4078 3 ปีที่แล้ว +1

    Do you have a best to worst video on all the meds you've discussed?

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      That's a good question. I haven't done anything like that because there's not really any one medication that's best or worst for everyone. Choosing a diabetes therapy is (or at least should be) a highly individualized selection based on many different factors. Otherwise, that would be a great idea.

  • @codyalt5871
    @codyalt5871 3 ปีที่แล้ว +2

    I was on jardiance it worked great. My new job doesn’t cover it like my old one did. Any cheaper alternative without shots you’d recommend?

    • @sugarhighchannel
      @sugarhighchannel  3 ปีที่แล้ว +1

      Steglatro is in the same family as Jardiance, but sometimes cheaper, depending on the insurance plan.

  • @kms250
    @kms250 3 ปีที่แล้ว

    Thanks to the Gila monster all of this is possible!

  • @luckychucky3426
    @luckychucky3426 2 ปีที่แล้ว

    I try to get my insurance company to pay for it I'm a senior a lot of money nobody seems to want to pay for it

  • @carolinepandian8630
    @carolinepandian8630 2 ปีที่แล้ว

    Meeting Dr IGUDIA TH-cam channel was the beginning of a new life for me after using his herbs medication in curing my Diabetes disease.

  • @geminiganesh7885
    @geminiganesh7885 4 ปีที่แล้ว +1

    1. should this GLP1 be used for life time? if so how often and what pancreas tests to be done?
    2. if someone started on Byetta daily 2 injections few years back, and still working, is there a need to change to different GLP1 group (except convenience) ? please clarify. thanks,

    • @sugarhighchannel
      @sugarhighchannel  4 ปีที่แล้ว

      gemini ganesh Good questions. As far as using GLP1 meds for lifetime, it really depends on the reason one is taking it. If the main goal is just to manage blood sugar/diabetes (assuming there’s no other cardiovascular disease or concern), then it only needs to be continued as long as it’s necessary to keep the glucose in range. Diet changes and weight loss can often improve metabolism so much that the medication is no longer necessary and can be stopped. If someone with diabetes is taking it for the purposes of reducing the risk of cardiovascular disease, then the expectation would be that he/she would continue it for life, since cardiovascular risk increases as we get older.
      If Byetta is working well, the only real reason to change would be for the convenience of less frequent dosing. However, the effect of Byetta on cardiovascular disease has never been studied, so we don’t really know if it brings about the risk reduction that many of the others do. So one could argue that there could be a benefit in changing from Byetta to another GLP1 med with PROVEN cardiovascular risk reduction if that person is considered at increased risk.

  • @janmosher4265
    @janmosher4265 3 ปีที่แล้ว

    👍

  • @luckychucky3426
    @luckychucky3426 2 ปีที่แล้ว

    Give me a break the prices of these things 800 $900 give me a break

  • @pinkiipinku
    @pinkiipinku 3 ปีที่แล้ว

    Hold on my doctor prescribed victoza to me for weight loss.. smh

  • @ENIAWOOD
    @ENIAWOOD 3 ปีที่แล้ว +1

    Danny Devito stunt double? Interesting 🧐😅

  • @nancyshirah8427
    @nancyshirah8427 2 ปีที่แล้ว

    Farts are always funny js

  • @pastorapostledeborahlouise5031
    @pastorapostledeborahlouise5031 4 ปีที่แล้ว +4

    Ozempic cause me eye problems were they wanted to stick a needle in my eye and draw fluid out and I didn't have no problem till I start using ozempic and make you nauseous and throwing up and I don't want to do none of it

  • @cheryllittle7578
    @cheryllittle7578 3 ปีที่แล้ว +4

    Looove how well u can talk on this topic in a easy to understand way! Fab info packed vid 😃 Def going to check out ur playlist

  • @boolanny
    @boolanny 4 ปีที่แล้ว +2

    so i guess tekashi 69 shouldn't use glp-1 meds...or maybe he should...i dunno...lol

  • @ScottPaddock
    @ScottPaddock 3 ปีที่แล้ว +2

    I wish I would have seen this video 4 years ago when I went on long-release insulin combined with glipizide. I was recommended a GLP-1, but the black box label scared me because of thyroid issues in my family. I've recently been having some low blood sugar scares in the middle of the night. I just messaged my doctor about switching to a GLP-1. Thanks for all of your info!!!!

  • @rmdebora
    @rmdebora 3 ปีที่แล้ว +23

    My endocrinologist gave me ozempic to loose weight together with diet and exercise. I don't have diabetes but it really helps with my endless hunger feeling and it's working. I'm loosing weight and just feel sick sometimes .

    • @Brian.8272
      @Brian.8272 3 ปีที่แล้ว +1

      i had a heart attack in January, I have a1c of 5.5 and glucose of 114. I'm 5'7" and 52 years old 186 pounds, would a doctor prescribe me glp-1 medication?

    • @kylina3432
      @kylina3432 2 ปีที่แล้ว +1

      @@Brian.8272 I am not sure if you saw that your message was a reply to the person talking about her story or if you were trying to ask the maker of the video. If you are trying to ask the video maker the I would say to ask the question again in the comments section. I don't have diabetes but am close to being and I have been given Ozempic. I would say talk to your doctor. My doctor hadn't even heard of it yet and after reading she said yes we can definitely give this a try...

    • @mfbs60
      @mfbs60 2 ปีที่แล้ว +1

      @@Brian.8272 I endocrinologist prescribed to me the GlP 1 , but i am a thyroid cancer survival, as well side effects says do not take glp 1 if you had thyroid cancer. I am afraid 😨 my mind tells me to do not take it, what I shall do!!! ?

    • @jdmullen78
      @jdmullen78 ปีที่แล้ว +1

      @@Brian.8272 mine did. I am taking Bydureon now. She originally said Ozempic but insurance wouldn't pay and Bydureon is 20% cheaper (still pretty expensive).

  • @weezie8237
    @weezie8237 3 ปีที่แล้ว +2

    Thank you for clearing up a few things. I was going to ask if it’s ok to use Ozempic for weight loss ? My doctor prescribed this to help me with stubborn weight that I just cannot get rid of. I see rmdebora is in the same situation and it’s helping her, thank you rmdebora for your comment, it helped me too !