Cool thing about Aggarwal homologation is the application of Horeau's principle - even after many steps of homologations, his methods can essentially generate a single diastereomers among thousands of possibilities
Super glad I found this channel. Truly makes me want to relearn everything in organic chemistry again. It’s such a fun topic to learn about. During your studies in organic chemistry, was there ever a time where you had to learn the physics about what exactly is going on? Because I love physics as much as I love chemistry and I hope to do some form of career regarding the two.
Yeah physical chemistry is definitely a whole discipline of chemistry; I’ve done a few courses on phys chem, but depending on where you go, you could even do a PhD in that area
Well, you should try out inorganic chemistry. Many concepts get described by the quantum mechanics and sometimes even classical mechanics! In our field, they are working on new type of batteries (without Li, since there isnt enough on earth) and it's a hybrid of chemistry and physics. But if you really like organic chemistry, don't be afraid. Nowdays, organic molecules are used as replacement for inorganic materials (for example: organic molecules in solar panels). Chemists would love using organic molecules since there are so many possibilities just because the C-C bound is strong! The only problem with organic molecules is the fact that they aren't as stable inorganic molecules (on long term) Also, organic chemistry isn't as strict as inorganic. For example, the yield of your targetproduct is sometimes like 30%. Just because so much can happen with the reagens in your setup. I've noticed that physicist of my group can't 'handle' this and are annoyed by this. That's the difference between chemistry and physics. We, the chemist, expect things and are making theories for the observed reactions, yields,... . While physicist make a stunning theory and want to change the reality! I hoped this helped, this is my view on the topic
Hi, I really love ur videos. Could u make in the future video about Sharpless dihydroxylation or asymmetric epoxidation and their subsequent transformations? Thumbs up for ur work
I definitely will - I'm going to continue my series on 1,2-shifts for a few more videos at least, but I will definitely cover these topics in the future!
Hello, could you maybe recommend sources for total synthesis of any molecule that I am interested in? What journals, patent databases, books, websites (SciFinder, Reaxys etc.) should I first look into for total synthesis? Could you maybe cover this topic in one of your future videos? It would be great to know how a Chemist with a PhD in Organic Chem does research. I really like your videos and you are encouraging me to study organic chemistry in my spare time. Will take some time though. Keep up the good work!
EJ Corey’s ‘classics in total synthesis’ is a good place to start - I’m sure if you ask people in the discord, they will have other suggestions as well!
If you already have a strong synthetic background, the total synthesis of vitamin B12 is a really impressive piece of work - but the channel’s community discord is a great place to find some guidance in general!!
Hi...your videos are awesome....can you make more videos on basic topics like this and also on rxn mech like sn1 and sn2 and stuff.....greetings from India
Ok so we're at boron already, where's the FLPs edit: I hate markovikov rule for the exact reason that there's an anti to the rule. What's the value of a rule if it's exceptions are valuable enough to have it's own rule. I guess calling it a rule is ticking me off since it has no predictive power, all hail synthons imho.
Hey I found your channel two days ago, and have been on a binge. Fantastic content.
Thank you!
Cool thing about Aggarwal homologation is the application of Horeau's principle - even after many steps of homologations, his methods can essentially generate a single diastereomers among thousands of possibilities
thanks for the lecture! It was very cool
Glad you liked it!
Great video!
Thanks!
Super glad I found this channel. Truly makes me want to relearn everything in organic chemistry again. It’s such a fun topic to learn about.
During your studies in organic chemistry, was there ever a time where you had to learn the physics about what exactly is going on? Because I love physics as much as I love chemistry and I hope to do some form of career regarding the two.
Yeah physical chemistry is definitely a whole discipline of chemistry; I’ve done a few courses on phys chem, but depending on where you go, you could even do a PhD in that area
Well, you should try out inorganic chemistry. Many concepts get described by the quantum mechanics and sometimes even classical mechanics! In our field, they are working on new type of batteries (without Li, since there isnt enough on earth) and it's a hybrid of chemistry and physics.
But if you really like organic chemistry, don't be afraid. Nowdays, organic molecules are used as replacement for inorganic materials (for example: organic molecules in solar panels). Chemists would love using organic molecules since there are so many possibilities just because the C-C bound is strong! The only problem with organic molecules is the fact that they aren't as stable inorganic molecules (on long term)
Also, organic chemistry isn't as strict as inorganic. For example, the yield of your targetproduct is sometimes like 30%. Just because so much can happen with the reagens in your setup. I've noticed that physicist of my group can't 'handle' this and are annoyed by this. That's the difference between chemistry and physics. We, the chemist, expect things and are making theories for the observed reactions, yields,... . While physicist make a stunning theory and want to change the reality!
I hoped this helped, this is my view on the topic
Hi, I really love ur videos. Could u make in the future video about Sharpless dihydroxylation or asymmetric epoxidation and their subsequent transformations? Thumbs up for ur work
I definitely will - I'm going to continue my series on 1,2-shifts for a few more videos at least, but I will definitely cover these topics in the future!
Hello, could you maybe recommend sources for total synthesis of any molecule that I am interested in? What journals, patent databases, books, websites (SciFinder, Reaxys etc.) should I first look into for total synthesis? Could you maybe cover this topic in one of your future videos? It would be great to know how a Chemist with a PhD in Organic Chem does research.
I really like your videos and you are encouraging me to study organic chemistry in my spare time. Will take some time though. Keep up the good work!
EJ Corey’s ‘classics in total synthesis’ is a good place to start - I’m sure if you ask people in the discord, they will have other suggestions as well!
If you already have a strong synthetic background, the total synthesis of vitamin B12 is a really impressive piece of work - but the channel’s community discord is a great place to find some guidance in general!!
Thanks a bunch, I will definetly join.
i'm thinking of applying for a phd with aggarwal group !
Their work is really cool - I don’t personally know anyone in their group, but their research is great!
@@ThatChemistOld Turns out my current undergrad project tutor studied under him like 15 years ago!
That’s awesome
I can tell you that is an awesome group and Varinder is a very nice person
Since I am currently in his group, very cool chemistry are being developed in his group and soon be online in some weeks
Hi...your videos are awesome....can you make more videos on basic topics like this and also on rxn mech like sn1 and sn2 and stuff.....greetings from India
Oh there are many basic chem videos.... I just didn't kneww....anyways thankss sirrrr
Ok so we're at boron already, where's the FLPs
edit: I hate markovikov rule for the exact reason that there's an anti to the rule. What's the value of a rule if it's exceptions are valuable enough to have it's own rule. I guess calling it a rule is ticking me off since it has no predictive power, all hail synthons imho.
That’s why I never talk about it - I don’t think it has much utility