Hmmm....it seems to me that there is no such thing as "bacterial soap." I mean, one of the biggest reasons we wash our hands is to remove bacteria. That is the point. Doesn't matter what you use, just wash your hands fairly frequently, for everyone's sake.
Steptoe Edwall Antibacterial soap is any soap that has additional antimicrobial chemicals added to it to purportedly kill more bacteria. The use of antibacterial soap has not shown to provide a significant benefit to health over regular soaps, and so it's suggested to not use antibacterial soaps in the concern that they may contribute to the growth of resistant bacteria.
nathan rous I think his point was pointing out that all forms of soap are 'anti-bacterial'. What would be the point of having a soap that effectively dopes your skin in bacteria. This actually brings up an interesting point about advertising too, how some adverts and companies use 'anti-bacterial' like it's a new thing. The only reason I can think this can be used is because it somehow actively fights of bacterial infections long after it's initial application.
***** Regular soap is not antibacterial in the same sense. The soap itself will adhere to the bacteria, and rubbing with soap will then physically tear up the cells of bacteria, then help rinse it away.
It makes me angry when people stop medication early when they feel better. The only reason you should stop early if the medication adversely affects you, and even then, only under doctor recommendation.
The only time i actually stopped medication early was with Dilaudid. I didn't feel like i needed it and i had enough prescribed to kill an elephant. But i took all the antibiotics as prescribed.
Apparently, there is growing evidence that stopping antibiotic treatment "early" might be just as effective as a prolonged treatment, while reducing the risk of developing antibiotic-resistant strains. Sounds crazy I know, but here is what the WHO says: "Evidence is emerging that shorter courses of antibiotics may be just as effective as longer courses for some infections. Shorter treatments make more sense - they are more likely to be completed properly, have fewer side effects and also likely to be cheaper. They also reduce the exposure of bacteria to antibiotics, thereby reducing the speed by which the pathogen develops resistance." www.who.int/features/qa/stopping-antibiotic-treatment/en/ www.bbc.com/news/health-40731465
Just plain old criminal negligence . What we need is for pharmacists , vets , drug manufacturers and drug suppliers to stop supplying the latest drugs for livestock . Look up the research . When we end up with traces of these drugs in our foods that bugs can overcome . That is why we have resistance to even the latest drugs . This is of even greater concern than patient non compliance . This should be made criminal offence internationally . Otherwise no one will save us from the pandemic to come .
Here are four strategies to help combat drug resistance: 1. Vaccines - prevention is better than the cure! 2. Sanitation and Hygiene - again... prevention! 3. Eliminate the unnecessary use of antibiotics in livestock. 4. Educate doctors and the public to limit antibiotic use - too many antibiotics are improperly used to combat viral infections.
Pocket Global Health Wait what? Antibiotics don’t work against viruses, and vaccines don’t work against bacteria. Sanitation and hygiene can only get so far, the problem with superbugs is that people who come out of surgery are more prone to them, since they are in hospitals. Reducing antibiotic use would be difficult, but we in the west eat too much meat anyways so it’s very important. Also the doctors know, but there might be problems with liability if they don’t provide the antibiotics. IMO we should invest in phage therapy.
Sampling Reality Currently, according to graphs I found, The countries that consume the most antibiotics per person is Greece... and France China and India DO consume a lot, but keep in mind they have over 1 billion people there, so per-person it is not a lot.
Sampling Reality im asian, my entire line of living family members know not to overuse anti biotics, yes hospitals in china has shit ton of bags with antibiotics that drip into blood, but thats for serious illness and not just a headache. idk about the people in china but in america antibiotics are basically as popular as mcdonalds
Andylink007 Really... really? You defend YOUR country of origin and then insult someone elses... where is this conversation going to lead to? What are you adding to this?
Putting it in animal feed, cows and chickens mainly due to terrible conditions causing infections accounts for, I believe, around 75% of antibiotic usage in the U.S. Also some patients, will want an antibiotic for viral infections then when a care provider says no it's a virus they will go to another dr until they get what they want. Patients need to deal with it and trust their doctors.
By far the most overused anti-biotics are used in animal feed which is the Largest market for anti-biotics the largest percentage of our anti-biotic production
Over-prescription is only one cause of resistance. Misuse by patients (like not following directions, stopping before the prescription’s finished) and the vast use in food animals, are 2 other important factors; but resistance will evolve eventually in any case!
YES THANK YOU OMG people need to understand that taking antibiotics every time you get a cold is pointless... I've had quite a few sore throats in the past couple years, and when they got bad enough I went to the doctor to make sure it wasn't strep, since strep can spread and infect your organs and all that fun stuff. But my doctor kept refusing to swab me, saying it would take too long to culture, and just gave me antibiotics anyway. And since strep is the only bacterial infection that causes sore throats, the others being viral, unless it actually WAS strep, taking antibiotics would be more harmful than anything. I only took them the one time I was 99% sure it was actually strep.
It's mind boggling how many people don't know what antibiotics are used for and will just pop some leftover amoxicillin cause they have a stuffy nose. Completely unaware why that's bad, or why it was bad that they had leftover amoxicillin to begin with.
As a pharmacy student here at UM, thank you so much for putting this video up, especially for the last minute explanation of how people can do their part!
I'm hardly ever ill, and I never take drugs when I am, I get better naturally and usually quite fast. Now, I've got no scientific backup for this bold statement, but I'd say that people around me taking drugs as soon as they feel dizzy and beyond actually get ill more often...
I have to agree with you, while I do take drugs for pain (as I have lupus and a chronic pain disorder) I find that those I grew up with that stayed at home taking medication with the slightest sniffle, seemed to get sick more often and still have trouble getting over anything now that they're adults.
This is basically an exercise in correlation versus causation. What reason do you have to believe that frequent use of medication leads to more frequent illness, rather than the equally valid possibility that people who are ill more often are more likely to frequently take medication? Even disregarding the plethora of other possible explanations of course, including the chance that there isn't a correlation and you're only thinking there is.
Elizabeth Rasco Colloidal silver doesn't do anything for you besides slowly give you argyria. Silver isn't toxic enough to humans to do much harm besides that, but it certainly is not effective as an antibiotic or as really anything else. Its ineffectiveness for treating what people say it treats has been well-established for decades. Please stop using it. Seriously.
Vulcapyro Good point, never thought of it that way. Anyway, taking more and more medication would make bad bacteria more resistant and natural antibodies less resistant.. no ?
The superbug thing scares me, but you know... deep down inside, I will confess that I think a plague might do the world a bit of good. I hate thinking that, but I can't help it.
Two can play at that game, we can use evolution to fight super bug too. Force fungus, who originally create those antibiotic, to fight those super bugs. Spray some x-ray to make them mutate faster, and maybe they will make some new antibiotic.
Using radiation, that damages the DNA randomly and in the most cases rather destroys the whole organism, than forcing a mutation, isn't the way we would do it today. (In general I think, that using other methods like certain toxics are more efficient to force mutation, aren't they?) We are already able to just "build" a living organism completely on our own. So why don't we just hook up an artificial neural network to the necessary equipment and let our technology just develop the cure for us. (Our modern neural networks and our "organism manufacturing" tools are already advanced enough to do that.)
Ooorr, we can just shoot x-rays at a lizard until we create Godzilla. Then, we shoot more x-rays at Godzilla until one of his decedents is microscopic and able to fight the bacteria in hand to hand combat.
I agree cutting and pasting gene is more efficient than x-ray. However, we still don't have the ability to design new complicated gene. We are only good at copying from nature. Thus, randomly typing is the only way to write something new. If infinite number of monkey type a book, one of them will eventually able to write Shakespeare. The problem with random is that we won't know how long it take for mutation to work its magic because it take a lot of luck and time. Oh X-ray mutation is actually very common. We still use it to mutate our veggies to randomly make more efficient genes because that won't be consider GMO for some reason and anti-GMO people have no problem with that.
I think I'd like to see an episode on the evolution of plants. Things like, how did we end up with carnivorous plants? What was the earliest known plant? What sorts of bizarre leafy fossils have been found? or even, what kinds of crazy plants do we have around the world now? Can we get a March of Progress with plants? (Would it be more like a March of Photosynthesis?)
David Attenborough made a wonderful documentary about plants not that long ago. Maybe check it out if you're still looking for something like that. It's not really a march of progress. But I think you'd really like it.
Not sure if this is a result of the new host(s) or not, but this video had an *awesome* amount of information in it. I'd love to see more videos of this quality in the future!
Is it Nurgle at work, creating more virulent infections, forcing us to persevere in the face of future plagues? Or is it Tzeentch, guiding the hand of evolution while we hope to keep ahead of it?
But perhaps it is Khorne at and his minions at work, devilishly enhancing our enemies with blessings and weaponry to destroy our most fearsome of warriors?
As a biochemist conducting research on antibiotic resistance, it was really comforting to see a successful attempt at educating the general population about how much of a big deal this issue is. Thanks! :D
sageyash Both of them are great!! I'll listen to hank more in the daytime, Michael's voice is great for when I'm sleepy but refuse to stop learning at 2am 😂
Please please please please PLEASE do a video on Tuberculosis! I'm studying it currently and I'm interested in what the Scishow crew has to say about it!
Bacteriophages was used to treat infections in the former Soviet Union, mostly in present day Georgia and Russia. It has not quiet caught on the rest of the world. The bacteria can't evolve to develop resistance like with antibiotics because the viruses that infect the bacteria are also evolving. This also implies that the virus strain have to be developed with the potency to combat the specific strain of infection in a given area. So it is difficult to mass produce the treatment centrally. They have to be developed closed to where the infection is present.
9:28 "The future peoples of earth will thank you" .. I dunno, we humans seem to have a long standing tradition of taking the sacrifices and efforts of past generations for granted.
No, I'm not going to be worried about this. Be mindful of proper antibiotic use, sure, but worry will only get you worry, and that's bad for your health.
i'll wash my hands if they are really dirty. if you wash your hands too much, or are generally a TOO CLEAN PERSON, your imune system will possibly be weaker and you will actually get sick much more quickly.
cyborgchimpy The immune system will not get weaker due to washing your hands. You will lose essential oils on your skin, and essential dead skin cells that act as a shield from bacterial and others. Therefore you will be more prone to get infections and diseases, that your immune system can handle well.
They do, but the bacteria don't enter the blood cycle or nerv systems or even the immune system in the body, they get warned off by the thick layer of dead skin cells. In addition, if you do get infected by bacteria, your immune system don't weaken, it gets stronger, making anti-bodies, phages, Killer-T-Cells and more, you actually make you immune system more immune to bacterial.
Jan Maddson hehe, I know but that was my point :P getting bacteria inside your body(to a certain extent ofcourse) makes your immune system stronger. so I think washing your hands overly much isnt a good thing
the CDC has found out the most effective way of preventing the spread of bacteria and its surprising -- proper hand washing techniques. i guess we're all going to have to learn how to do that, make it a habit, use proper gloving techniques when around sick people, wearing masks when we ourselves are sick (bless asian culture for doing that already)... one of the reasons for the rise of MRSA in hospitals is staff not using proper handwashing & gloving techniques...i've seen staff do this, the ones who should know better... and for those literalists, no, this doesn't stop people getting sick -- nothing is absolute in the meantime, i love hearing aboot the potential new antibiotics coming onstream; when humanity is stressed, we innovate like crazy :3
That actually may not be too far off in the distant future. I have heard that researchers are trying to get chemicals that are able to bond to the cell wall of only specific types of cells, such as cancer cells or bacteria. Attached to those special chemicals would be a radioactive particle that has a half-life of a couple hours to a few days. Anyway, the chemical bonds to a bacterium or a cancer cell, and the radioactive particle kills the cancer cell or bacterium, and then after a short while the radioactive particle decays into an inert substance. It's like each molecule has it's own light saber. The hardest part is finding a chemical that bonds only to a single type of cell. Once they figure that out, they estimate that curing cancer or killing the bacteria will have zero side effects to the patient.
I don't know anything about this stuff, but from what you said I imagine another line of defense might be to (bio)engineer bacteria that have "bad" genetics, and then infect people who have an infection with either alive or dead ones of them... maybe the existing infection would exchange/steal the bad genetics of the engineered ones, either directly destroying them or giving them a vulnerability that an antibiotic could finish the job. Of course you'd have to also engineer them so they don't take genetics from the existing bacteria you're trying to kill... just a thought, but the other methods they've been working on sound less complex and more promising anyways
i say lets make nano technology that bacteria can't destroy because there metal, yeah it could destroy the world, but it would still kill the bacteria!
The bacteria with the "bad genetics" might be able to transfer some of their genes to the scary ones, but all of the bacteria with the "bad genes" would then die fast. There would always be bacteria left with antibiotica resistence, which could divide and pass their genes on. It's all about evolutionary pressure here... so this would unfortunately not work. The gene transfer among bacteria is btw. a very undirected process - u need to be kind of lucky that your bacteria really passes the genes on. Phages, however, are designed to insert their genomes into the next bacterium that fits them, so that's the better way =)
I think it's also good to take probiotics during and after a course of anti-biotics, as current antibiotics don't discriminate between your good bacteria that keeps you healthy and the bad stuff.
i remember my doctor always prescribing me antibiotics everytime my parents took me to him when i was sick. i believe doctors still use them way too often.
"If there is one thing the history of evolution has taught us it's that life will not be contained. Life breaks free, it expands to new territories and crashes through barriers, painfully, maybe even dangerously, but, uh... well, there it is." - Dr. Ian Malcolm, Jurassic Park This is something we should think of before we playing with the nature.
...except for all those species we forced into extinction. Also basically supper bugs put us back to pre antibiotic times, no better no worse, except we gained vast amounts of information on bacteria and had more minds live longer. In other words there was absolutely no downside to the advent of antibiotics, (sure we miss used them ). Your quote has the meaning that we shouldn't try and slap nature, but even if super bugs take hold antibiotics where unquestionably a successful slap to nature. (Also life may never really break through as it hasn't yet and we are working on solutions to this). So yeah I support playing with nature, I hope we keep playing with nature and bitch slap super bugs too.
Tim Swingler What I meant was that we can't control life, even if we think we can. If we develop an antibiotic and start to using it everywhere; life will find a way out.
One of my microbiology lecturers at college told us, in our first year, that we all had to go watch "Contagion" for our homework. Because what happens in that movie WILL happen to the human race one day. And it's not a matter of if. It's a matter of when. Contagion is a fairly scientifically accurate way to look at our future semi-apocalypse. I recommend you all go watch it too!
An epidemic is more local to a region. The word you're looking for is a pandemic. I said "semi-apocalypse" because an apocalypse wipes out all but a small handfull, whereas a super bug is likely to leave millions, if not billions, of people.
thanks for this video! it has EVERYTHING, important complete and summed up information, and most importan, as a Doctor doing my social service, i really appreciate the message about antibiotic resistance and how to prevent it, you don't have an idea how mad it makes me when my patients come and say... i took these pills that are like tiny and round, my neighbour gave them to me because he says they cured him... makes me real mad! Even now that we have a law in Mexico to sell antibiotics with a prescription only, this keeps happening and makes our work harder... i could go on and on, but i only want to thank you and congratulate you guys!
As I understand it, a large part of the failure of antibiotics was due to, or at least accelerated by, extreme negligence in the prescribing and use of them. Even things like antimicrobial soap just increase the problem. No matter what we come up with next bacteria will evolve toward surviving it's effects. If we have not started to control our foolish use of these things it will occur rapidly.
Medicating cattle because they're kept in conditions where they'd all die without the copious amount of meds they're given isn't helping at all. Also thinking about it how is keeping cattle in conditions where they can't even move not animal abuse?
True, but you also have to remember natural selection occurs naturally, so there is/was nothing we could really do to stop it. True we accelerated the process, but as the french say "C'est la vie", such is life. Besides I've had a good, but short, life and death is just the next step in the cycle of the universe.
Lol medicating cattle ... Let's all fear the cattle bacterium most of those ... Don't bother us. It's all about mommy taking Timmy to the doctor and demanding antibiotics for his cold, and idiots not taking the full doses
Bacteria are smart, scary and deadly. We shouldn't forget the wonderful bacteria in our body that are awesome and make help us do our whole "living" thing.
Michael Aranda is the kind of person who i would least expect to be a Host of Sci Show at first glance, but seeing him here i am actually quite impressed.
I think our best bet (Though I'm not nearly well enough informed to say for certain) is to work on lab created and targeted bacteriophages. Since the only thing more destructive on a microbiological level than us are viruses, and since viruses are basically biological machines, it does seem possible to get to the point where we can manipulate the genes of one to target and destroy on type of bacteria.
I was thinking maybe even nanobots. the technology in them is complex, but there isn't really much stopping a nanobot. The whole gray goo theory scares me though.
The thing is, practically speaking, Viruses are biological nanobots. They are tiny little organisms that have one specific purpose. The great thing about them is that because of the millennia they have been around, they are relatively stable, and unlikely to suddenly kill everything the way one mistake with a nanobot can. They are also prebuilt with the purpose we need them to do, the bacteriophages at least. While nanobot technology is still ages off, we can mess around with bacteriophages and put them to use today.
Current FDA regulations make it hard to bacteriophage research to make it to human trials. As it stands today, each particular phage has to be treated as if it is a drug of its own (and I'm sure you're somewhat aware of how long and expensive it is for drugs to go through those trials). The problem is is that it is more effective to treat infections with a cocktail of bacteriophages (since they are very specifically targeted). A really good article that covers all this can be found here: journal.frontiersin.org/Journal/10.3389/fmicb.2012.00238/full
Everytime I watch one of these episodes, my brain grows a tiny bit. One day after watching all of these videos, I will be able to move things WITH MY MIND!
always bothers me, the verbiage used to describe the process(es) that occur in micro evolution. The bacteria don't "have a strategy" they don't "develop better weapons systems" nor do they "plan" or "figure out" things. As far as we know it's random chance, changes happen not for a particular purpose or because of a need, but just because changes happen. Bacteria or insects or whatever life form doesn't have a meeting and plan out the strategy they will use to defeat the enemy. They have some members that are slightly different in each of many millions of ways and sometimes some of those ways are significantly better than the others. this is when a species has a genetic bottleneck and afterwards they either completely die off or the new strains repopulate their environments all or most carrying the new traits, where new small deviations start accumulating again for when the next threat to the species happens. sorry to nit-pick but it just seems like our language doesn't have the right words to describe this phenomenon adequately.
+richard reeves How does this sit with you: "Like the evolution of any other organism, bacteria that acquire the toughest, most resistant become more fit -- more adaptable to a range of environments -- and are thus more likely to survive and thrive."
+richard reeves I understand that it bothers you, as a physicist, I also often get a little upset about people using the wrong words when explaining something scientific. But you have to consider that this kind of youtube channels are made for a wide array of different people, not only experts. Since this is the case I can understand that they want to present the topic as colourfull, interesting and understandable as possible. Kinda like a childs book so to speak.
The plague only killed about a third of the populace, which means you have a 66.667% chance. Better odds if you live in the countryside or are a hermit.
Another problem is that very very little work is being done by major drug companies to develop new antibiotics as most companies are more interested in drugs you need to take for the rest of your life rather than 3 weeks as it is more profitable it's really appalling
+Joshua Lansell-Kenny Not to mention the fact that technological research, including medical, is treated as intellectual property. So instead of free-floating in the creative commons for anyone with a bright idea to build off of, any progress being made by a major company can get its plug pulled due to funding problems or the researchers just hitting a dead end, and then spend the next couple years AT LEAST languishing away as the guarded territory of a company doing nothing with it. It's really sickening, and it's why I've decided to go into politics. While America desperately needs people going in to the STEM fields, my talents are best utilized managing the green paper and red tape. I think the general public thinks of lack of scientific breakthroughs in terms of "Not enough smart people having ideas" but the reality is often much more embarrassingly stupid.
+Breachi Chan Cancer research is big money, whos to say if a big company funded by charity would tell us if they found a cure for the biggest earning cancers? Its not ethical and a bit macabre but the prevalence of cancer only works to bring in more money for these companies. Making new medicines is not that hard on the grand scale but it does take a lot of time and money, money that investors want to profit from. New antibiotics might be held on to by big companies until there is a massive crisis and they can sell the drugs at a premium to desperate people.
I'm incredibly thankful for my immune system. I VERY rarely get sick any more, even if literally EVERYONE around me (thank you, office job) gets sick. However, if the next black plague is a variation of strep, I'm fucked >.>
I have a solution. Make a gas that kills all harmful bacterial and does nothing else then release it into the air so that it's all over the globe. About as reasonable and serious.
Think about all the projects that Hank manages... he has way more on his plate than I could ever deal with (low stress tolerance...) so if he has to skip an episode once in a while, who are we to complain? Besides, Michael is really cute. ;P
Also, don't use antibacterial soap! Doesn't work any better than regular, and encourages resistant bacteria
Hmmm....it seems to me that there is no such thing as "bacterial soap." I mean, one of the biggest reasons we wash our hands is to remove bacteria. That is the point. Doesn't matter what you use, just wash your hands fairly frequently, for everyone's sake.
^it was mentioned as "antibacterial soap" not "bacterial soap".
Steptoe Edwall Antibacterial soap is any soap that has additional antimicrobial chemicals added to it to purportedly kill more bacteria. The use of antibacterial soap has not shown to provide a significant benefit to health over regular soaps, and so it's suggested to not use antibacterial soaps in the concern that they may contribute to the growth of resistant bacteria.
nathan rous I think his point was pointing out that all forms of soap are 'anti-bacterial'. What would be the point of having a soap that effectively dopes your skin in bacteria.
This actually brings up an interesting point about advertising too, how some adverts and companies use 'anti-bacterial' like it's a new thing. The only reason I can think this can be used is because it somehow actively fights of bacterial infections long after it's initial application.
***** Regular soap is not antibacterial in the same sense. The soap itself will adhere to the bacteria, and rubbing with soap will then physically tear up the cells of bacteria, then help rinse it away.
It makes me angry when people stop medication early when they feel better. The only reason you should stop early if the medication adversely affects you, and even then, only under doctor recommendation.
The only time i actually stopped medication early was with Dilaudid. I didn't feel like i needed it and i had enough prescribed to kill an elephant. But i took all the antibiotics as prescribed.
Apparently, there is growing evidence that stopping antibiotic treatment "early" might be just as effective as a prolonged treatment, while reducing the risk of developing antibiotic-resistant strains. Sounds crazy I know, but here is what the WHO says: "Evidence is emerging that shorter courses of antibiotics may be just as effective as longer courses for some infections. Shorter treatments make more sense - they are more likely to be completed properly, have fewer side effects and also likely to be cheaper. They also reduce the exposure of bacteria to antibiotics, thereby reducing the speed by which the pathogen develops resistance."
www.who.int/features/qa/stopping-antibiotic-treatment/en/
www.bbc.com/news/health-40731465
Just plain old criminal negligence .
What we need is for pharmacists , vets , drug manufacturers and drug suppliers to stop supplying the latest drugs for livestock .
Look up the research . When we end up with traces of these drugs in our foods that bugs can overcome . That is why we have resistance to even the latest drugs . This is of even greater concern than patient non compliance .
This should be made criminal offence internationally .
Otherwise no one will save us from the pandemic to come .
Here are four strategies to help combat drug resistance: 1. Vaccines - prevention is better than the cure! 2. Sanitation and Hygiene - again... prevention! 3. Eliminate the unnecessary use of antibiotics in livestock. 4. Educate doctors and the public to limit antibiotic use - too many antibiotics are improperly used to combat viral infections.
Pocket Global Health Wait what? Antibiotics don’t work against viruses, and vaccines don’t work against bacteria. Sanitation and hygiene can only get so far, the problem with superbugs is that people who come out of surgery are more prone to them, since they are in hospitals. Reducing antibiotic use would be difficult, but we in the west eat too much meat anyways so it’s very important. Also the doctors know, but there might be problems with liability if they don’t provide the antibiotics. IMO we should invest in phage therapy.
"Lets say bobby and benny were feeling frisky..." XD
UNDERTALE?
+SunnyTheGamer74 / STG74 undertale didn't exist in the public eye 8 months ago.
" I caught the flu from you and got your mother's eyes " LMAO I really enjoyed this episode as TERRIFYING AS IT IS!!!
And Sulfa is the terrifying part for myself...ALLERGIC
THANK YOU FOR SAYING ALWAYS FINISH YOUR ANTIBIOTIC REGIMEN I TELL PEOPLE THIS ALL THE TIME IT'S SO IMPORTANT.
SciShow, keeping you up at night since 2012.
My mom always said not to take anti biotics unless you had to. I guess too many Americans don't know that.
It's also asians. They eat antibiotics like candy in China/India.
Sampling Reality Really. I'm pretty sure as an Asian, that is not true.
Sampling Reality Currently, according to graphs I found, The countries that consume the most antibiotics per person is Greece... and France China and India DO consume a lot, but keep in mind they have over 1 billion people there, so per-person it is not a lot.
Sampling Reality im asian, my entire line of living family members know not to overuse anti biotics, yes hospitals in china has shit ton of bags with antibiotics that drip into blood, but thats for serious illness and not just a headache. idk about the people in china but in america antibiotics are basically as popular as mcdonalds
Andylink007 Really... really? You defend YOUR country of origin and then insult someone elses... where is this conversation going to lead to? What are you adding to this?
"Catching a virus, robbing a dead friend, or having sex with a live one" pretty much sums up my college experience.
Same, except I wasn't so fussy on the "live" part....
Ooshgaar that is weird....I'm not even going to comment (even though I just did) lol
Ooshgaar A hole is a hole bro.
I blame antibiotic resistant to doctors that prescribe it like candy.
And the FDA for allowing it in our food source.
Putting it in animal feed, cows and chickens mainly due to terrible conditions causing infections accounts for, I believe, around 75% of antibiotic usage in the U.S. Also some patients, will want an antibiotic for viral infections then when a care provider says no it's a virus they will go to another dr until they get what they want. Patients need to deal with it and trust their doctors.
By far the most overused anti-biotics are used in animal feed which is the Largest market for anti-biotics the largest percentage of our anti-biotic production
Over-prescription is only one cause of resistance. Misuse by patients (like not following directions, stopping before the prescription’s finished) and the vast use in food animals, are 2 other important factors; but resistance will evolve eventually in any case!
Boy ain't that the truth! I had seen a report about how doctors worldwide have been overprescribing antibiotics for decades!
I'm mesmerized by his wobbling earlobes
"The future people of earth will thank you"
*becomes a future person of earth as 0.5 of a second passes*
"Thank you for watching..."
I think I just died
YES THANK YOU OMG people need to understand that taking antibiotics every time you get a cold is pointless...
I've had quite a few sore throats in the past couple years, and when they got bad enough I went to the doctor to make sure it wasn't strep, since strep can spread and infect your organs and all that fun stuff. But my doctor kept refusing to swab me, saying it would take too long to culture, and just gave me antibiotics anyway. And since strep is the only bacterial infection that causes sore throats, the others being viral, unless it actually WAS strep, taking antibiotics would be more harmful than anything. I only took them the one time I was 99% sure it was actually strep.
It's mind boggling how many people don't know what antibiotics are used for and will just pop some leftover amoxicillin cause they have a stuffy nose. Completely unaware why that's bad, or why it was bad that they had leftover amoxicillin to begin with.
As a pharmacy student here at UM, thank you so much for putting this video up, especially for the last minute explanation of how people can do their part!
I'm hardly ever ill, and I never take drugs when I am, I get better naturally and usually quite fast. Now, I've got no scientific backup for this bold statement, but I'd say that people around me taking drugs as soon as they feel dizzy and beyond actually get ill more often...
I have to agree with you, while I do take drugs for pain (as I have lupus and a chronic pain disorder) I find that those I grew up with that stayed at home taking medication with the slightest sniffle, seemed to get sick more often and still have trouble getting over anything now that they're adults.
This is basically an exercise in correlation versus causation. What reason do you have to believe that frequent use of medication leads to more frequent illness, rather than the equally valid possibility that people who are ill more often are more likely to frequently take medication?
Even disregarding the plethora of other possible explanations of course, including the chance that there isn't a correlation and you're only thinking there is.
I prefer natural remedies like using colloidal silver as an antibiotic
Elizabeth Rasco Colloidal silver doesn't do anything for you besides slowly give you argyria. Silver isn't toxic enough to humans to do much harm besides that, but it certainly is not effective as an antibiotic or as really anything else. Its ineffectiveness for treating what people say it treats has been well-established for decades. Please stop using it. Seriously.
Vulcapyro Good point, never thought of it that way. Anyway, taking more and more medication would make bad bacteria more resistant and natural antibodies less resistant.. no ?
The superbug thing scares me, but you know... deep down inside, I will confess that I think a plague might do the world a bit of good. I hate thinking that, but I can't help it.
True but I'd prefer if it didn't happen this generation.
I would prefer a zombie apocalypse
Thanos?
@@JC19021 Well too bad!
Looks like we need to go all borg on this issue and invent nanoprobes to defend our bodies from infections.
lol just said this as another comment, didn't see your comment here. I discussed it in some detail if you're interested in finding it.
***** Your profile pic fits so well with your comment.
*RESISTANCE IS FUTILE*
thank you for covering this important topic!
Two can play at that game, we can use evolution to fight super bug too.
Force fungus, who originally create those antibiotic, to fight those super bugs.
Spray some x-ray to make them mutate faster, and maybe they will make some new antibiotic.
Using radiation, that damages the DNA randomly and in the most cases rather destroys the whole organism, than forcing a mutation, isn't the way we would do it today. (In general I think, that using other methods like certain toxics are more efficient to force mutation, aren't they?)
We are already able to just "build" a living organism completely on our own.
So why don't we just hook up an artificial neural network to the necessary equipment and let our technology just develop the cure for us.
(Our modern neural networks and our "organism manufacturing" tools are already advanced enough to do that.)
Ooorr, we can just shoot x-rays at a lizard until we create Godzilla. Then, we shoot more x-rays at Godzilla until one of his decedents is microscopic and able to fight the bacteria in hand to hand combat.
stormtroopr1977 Open a Kickstarter! I'm in on that one! :D
I agree cutting and pasting gene is more efficient than x-ray. However, we still don't have the ability to design new complicated gene. We are only good at copying from nature. Thus, randomly typing is the only way to write something new. If infinite number of monkey type a book, one of them will eventually able to write Shakespeare.
The problem with random is that we won't know how long it take for mutation to work its magic because it take a lot of luck and time.
Oh X-ray mutation is actually very common. We still use it to mutate our veggies to randomly make more efficient genes because that won't be consider GMO for some reason and anti-GMO people have no problem with that.
stormtroopr1977
We are already bringing back wooly mammoth.
In a few decades, giant dinosaurs will be coming to your local zoos.
Yet again another awesome presentation from scishow
Good work, Michael.
Great episode, thank you!!
Best episode of Micheal to date, in my opinion. Great job! As if I didn't have enough things to worry about!
Best Scishow video yet! Great video Michael! Terrifying, but great! Keep up the great work!
What do you do when life gives you lemons? Make penicillin.
how. that's how fisicks works.
Awesome episode Micheal
Video quality and edit job on this was bumped up massively. .. whoever is behind this edit deserves a digital high five.
01101000 01101001 01100111 01101000 00101101 00110101!
I love how this video is long! Good job! and love the new guy.
I think I'd like to see an episode on the evolution of plants. Things like, how did we end up with carnivorous plants? What was the earliest known plant? What sorts of bizarre leafy fossils have been found? or even, what kinds of crazy plants do we have around the world now? Can we get a March of Progress with plants? (Would it be more like a March of Photosynthesis?)
David Attenborough made a wonderful documentary about plants not that long ago. Maybe check it out if you're still looking for something like that. It's not really a march of progress. But I think you'd really like it.
I love this! Extra long sci shows are the best!
this is probably michael's best vid yet
Thanks, that gave me exactly the motivation I needed to clean the house. I have to get rid of at least some bacteria.....
The biggest contribution to super bugs isnt from people, its from the food industry. Those animals are fed antibiotics every day of their lives.
Avoid animal food , go by plants and for protein take soya, lentils, and spinach
Awesome episode
Michael's best video.
they noticed my question, thanks SciShow
Not sure if this is a result of the new host(s) or not, but this video had an *awesome* amount of information in it.
I'd love to see more videos of this quality in the future!
You know I had a microbiology exam a couple of weeks ago that covered exactly this. Shame it only got posted now :(
Is it Nurgle at work, creating more virulent infections, forcing us to persevere in the face of future plagues? Or is it Tzeentch, guiding the hand of evolution while we hope to keep ahead of it?
But perhaps it is Khorne at and his minions at work, devilishly enhancing our enemies with blessings and weaponry to destroy our most fearsome of warriors?
Tartar Khorne try something subtle? Yeah, and Lorgar is an atheist.
What are you heretics discussing? I will report too the inquisition immediately!
As a biochemist conducting research on antibiotic resistance, it was really comforting to see a successful attempt at educating the general population about how much of a big deal this issue is. Thanks! :D
I like Michael more than Hank, he speaks clearly and calmly, so I don't have to keep rewinding to understand what he is saying (unlike Hank).
I respectfully disagree.
***** lmao ironic grammar
sageyash Both of them are great!! I'll listen to hank more in the daytime, Michael's voice is great for when I'm sleepy but refuse to stop learning at 2am 😂
Wow, that's one hell of a source list.
Great informative video.
Please please please please PLEASE do a video on Tuberculosis! I'm studying it currently and I'm interested in what the Scishow crew has to say about it!
This was incredibly informative. Thank you!
Bacteriophages was used to treat infections in the former Soviet Union, mostly in present day Georgia and Russia. It has not quiet caught on the rest of the world. The bacteria can't evolve to develop resistance like with antibiotics because the viruses that infect the bacteria are also evolving. This also implies that the virus strain have to be developed with the potency to combat the specific strain of infection in a given area. So it is difficult to mass produce the treatment centrally. They have to be developed closed to where the infection is present.
9:28 "The future peoples of earth will thank you" .. I dunno, we humans seem to have a long standing tradition of taking the sacrifices and efforts of past generations for granted.
It's alright though, they understand since they've done the same thing.
No, I'm not going to be worried about this. Be mindful of proper antibiotic use, sure, but worry will only get you worry, and that's bad for your health.
Wow thank you guys, that was one of the most useful scishow episode, i better go wash my hands now :)
i'll wash my hands if they are really dirty. if you wash your hands too much, or are generally a TOO CLEAN PERSON, your imune system will possibly be weaker and you will actually get sick much more quickly.
cyborgchimpy The immune system will not get weaker due to washing your hands. You will lose essential oils on your skin, and essential dead skin cells that act as a shield from bacterial and others. Therefore you will be more prone to get infections and diseases, that your immune system can handle well.
Jan Maddson dont your hands, which you touch everything with all day have a bunch of bacteria on them? foreign AND local bacteria.
They do, but the bacteria don't enter the blood cycle or nerv systems or even the immune system in the body, they get warned off by the thick layer of dead skin cells.
In addition, if you do get infected by bacteria, your immune system don't weaken, it gets stronger, making anti-bodies, phages, Killer-T-Cells and more, you actually make you immune system more immune to bacterial.
Jan Maddson hehe, I know but that was my point :P getting bacteria inside your body(to a certain extent ofcourse) makes your immune system stronger. so I think washing your hands overly much isnt a good thing
YOU,! Are NOT,!! Hank!!! Hank ! Hank! Hank! Hank! Hank!
the CDC has found out the most effective way of preventing the spread of bacteria and its surprising -- proper hand washing techniques.
i guess we're all going to have to learn how to do that, make it a habit, use proper gloving techniques when around sick people, wearing masks when we ourselves are sick (bless asian culture for doing that already)...
one of the reasons for the rise of MRSA in hospitals is staff not using proper handwashing & gloving techniques...i've seen staff do this, the ones who should know better...
and for those literalists, no, this doesn't stop people getting sick -- nothing is absolute
in the meantime, i love hearing aboot the potential new antibiotics coming onstream; when humanity is stressed, we innovate like crazy :3
And now 6yrs later you have been proved to be correct.
We need nano bots with tiny swords to cut the bacteria in half.
Wait...
NO, STOP, DON'T!
That actually may not be too far off in the distant future.
I have heard that researchers are trying to get chemicals that are able to bond to the cell wall of only specific types of cells, such as cancer cells or bacteria. Attached to those special chemicals would be a radioactive particle that has a half-life of a couple hours to a few days.
Anyway, the chemical bonds to a bacterium or a cancer cell, and the radioactive particle kills the cancer cell or bacterium, and then after a short while the radioactive particle decays into an inert substance.
It's like each molecule has it's own light saber.
The hardest part is finding a chemical that bonds only to a single type of cell. Once they figure that out, they estimate that curing cancer or killing the bacteria will have zero side effects to the patient.
I don't know anything about this stuff, but from what you said I imagine another line of defense might be to (bio)engineer bacteria that have "bad" genetics, and then infect people who have an infection with either alive or dead ones of them... maybe the existing infection would exchange/steal the bad genetics of the engineered ones, either directly destroying them or giving them a vulnerability that an antibiotic could finish the job. Of course you'd have to also engineer them so they don't take genetics from the existing bacteria you're trying to kill... just a thought, but the other methods they've been working on sound less complex and more promising anyways
Maybe a BIV (bacteria immunodeficiency virus) to fight the disease causing bacteria?
That's not too different from how a bacteriophage works.
i say lets make nano technology that bacteria can't destroy because there metal, yeah it could destroy the world, but it would still kill the bacteria!
The bacteria with the "bad genetics" might be able to transfer some of their genes to the scary ones, but all of the bacteria with the "bad genes" would then die fast. There would always be bacteria left with antibiotica resistence, which could divide and pass their genes on. It's all about evolutionary pressure here... so this would unfortunately not work.
The gene transfer among bacteria is btw. a very undirected process - u need to be kind of lucky that your bacteria really passes the genes on. Phages, however, are designed to insert their genomes into the next bacterium that fits them, so that's the better way =)
lmpeters Ah you are right.. I guess it came to my mind in this way first because it uses one of their own strengths against them
I think it's also good to take probiotics during and after a course of anti-biotics, as current antibiotics don't discriminate between your good bacteria that keeps you healthy and the bad stuff.
very informative, thank you...but also a bit scary.
i remember my doctor always prescribing me antibiotics everytime my parents took me to him when i was sick. i believe doctors still use them way too often.
"If there is one thing the history of evolution has taught us it's that life will not be contained. Life breaks free, it expands to new territories and crashes through barriers, painfully, maybe even dangerously, but, uh... well, there it is." - Dr. Ian Malcolm, Jurassic Park
This is something we should think of before we playing with the nature.
...except for all those species we forced into extinction. Also basically supper bugs put us back to pre antibiotic times, no better no worse, except we gained vast amounts of information on bacteria and had more minds live longer. In other words there was absolutely no downside to the advent of antibiotics, (sure we miss used them ). Your quote has the meaning that we shouldn't try and slap nature, but even if super bugs take hold antibiotics where unquestionably a successful slap to nature. (Also life may never really break through as it hasn't yet and we are working on solutions to this). So yeah I support playing with nature, I hope we keep playing with nature and bitch slap super bugs too.
Tim Swingler What I meant was that we can't control life, even if we think we can. If we develop an antibiotic and start to using it everywhere; life will find a way out.
Makeup and lighting is beyond crappy, you can hardly even recognize Hank...
you know its Micheal right?
***** I think that's the joke
***** - I did not know that. I did know it wasn't hank though, so Billy wasn't entirely off track here... ;)
Peter Qin - McKoy. Beast. He was played by Nicholas Hoult in X-Men First Class and the upcoming sequel.
Peter Qin Hank Green, the usual Sci Show host. c:
Omg I love the commentary of this episode so much!! 😂
my cat ate a scorpion a few days ago
was the scorpion ok?
Pieter vanderpol obviously not.
***** I don't think cats like salt
Did your cat acquire its poison? Can it inject the venom from its claws? That would be pretty cool.........
and mine ate a snake last month.
More new information, longer video, really educational and nicely explained
--> *Love it!*
One of my microbiology lecturers at college told us, in our first year, that we all had to go watch "Contagion" for our homework. Because what happens in that movie WILL happen to the human race one day. And it's not a matter of if. It's a matter of when. Contagion is a fairly scientifically accurate way to look at our future semi-apocalypse. I recommend you all go watch it too!
It's called an epidemic, it has happened before, it will happen again, and there is no such thing as a semi-apocalypse
An epidemic is more local to a region. The word you're looking for is a pandemic. I said "semi-apocalypse" because an apocalypse wipes out all but a small handfull, whereas a super bug is likely to leave millions, if not billions, of people.
thanks for this video! it has EVERYTHING, important complete and summed up information, and most importan, as a Doctor doing my social service, i really appreciate the message about antibiotic resistance and how to prevent it, you don't have an idea how mad it makes me when my patients come and say... i took these pills that are like tiny and round, my neighbour gave them to me because he says they cured him... makes me real mad! Even now that we have a law in Mexico to sell antibiotics with a prescription only, this keeps happening and makes our work harder... i could go on and on, but i only want to thank you and congratulate you guys!
As I understand it, a large part of the failure of antibiotics was due to, or at least accelerated by, extreme negligence in the prescribing and use of them. Even things like antimicrobial soap just increase the problem. No matter what we come up with next bacteria will evolve toward surviving it's effects. If we have not started to control our foolish use of these things it will occur rapidly.
While I largely agree, remember that there are appropriate uses for such things.
Medicating cattle because they're kept in conditions where they'd all die without the copious amount of meds they're given isn't helping at all. Also thinking about it how is keeping cattle in conditions where they can't even move not animal abuse?
True, but you also have to remember natural selection occurs naturally, so there is/was nothing we could really do to stop it. True we accelerated the process, but as the french say "C'est la vie", such is life. Besides I've had a good, but short, life and death is just the next step in the cycle of the universe.
Lol medicating cattle ... Let's all fear the cattle bacterium most of those ... Don't bother us. It's all about mommy taking Timmy to the doctor and demanding antibiotics for his cold, and idiots not taking the full doses
phyrath5 It is, but it makes money, so the organizations that should be putting a stop to it turn a blind eye.
Hahah you're so silly and funny bro I was laughing the entire time you were giving us bad news, thanks!
hey i remember writing a paper on this for my college class
The fact this was made 7 years ago creates anxiety 😂🤣😂
Bacteria are smart, scary and deadly. We shouldn't forget the wonderful bacteria in our body that are awesome and make help us do our whole "living" thing.
Hank makes things more fun ;)
Michael Aranda is the kind of person who i would least expect to be a Host of Sci Show at first glance, but seeing him here i am actually quite impressed.
Bacteria God made Bobby and Bonnie, not Bobby and Benny!
Excellent primer and overview of antibiotics and their mode of action!
I think our best bet (Though I'm not nearly well enough informed to say for certain) is to work on lab created and targeted bacteriophages. Since the only thing more destructive on a microbiological level than us are viruses, and since viruses are basically biological machines, it does seem possible to get to the point where we can manipulate the genes of one to target and destroy on type of bacteria.
I was thinking maybe even nanobots. the technology in them is complex, but there isn't really much stopping a nanobot. The whole gray goo theory scares me though.
The thing is, practically speaking, Viruses are biological nanobots. They are tiny little organisms that have one specific purpose. The great thing about them is that because of the millennia they have been around, they are relatively stable, and unlikely to suddenly kill everything the way one mistake with a nanobot can. They are also prebuilt with the purpose we need them to do, the bacteriophages at least. While nanobot technology is still ages off, we can mess around with bacteriophages and put them to use today.
Current FDA regulations make it hard to bacteriophage research to make it to human trials. As it stands today, each particular phage has to be treated as if it is a drug of its own (and I'm sure you're somewhat aware of how long and expensive it is for drugs to go through those trials).
The problem is is that it is more effective to treat infections with a cocktail of bacteriophages (since they are very specifically targeted).
A really good article that covers all this can be found here: journal.frontiersin.org/Journal/10.3389/fmicb.2012.00238/full
Everytime I watch one of these episodes, my brain grows a tiny bit. One day after watching all of these videos, I will be able to move things WITH MY MIND!
Oh well...
*gets papercut*
Ow! Well that doesn't feel to good.
*gets really sick*
DAMN IT!
Recovers because the the immune system was allowed to run its course.
Matthew Dies due to MRSA induced septic shock....
Okay I wasn't sure before but after this one, you convinced me; you're an amazing host! Keep up the excellent work!
I blame those who don't finish their course of antibiotic..
Awesome video!
So if our medicine becomes primitive once again... Does that mean we'll fall back to the old idea of, "Oh... It's infected... Huh, just cut if off."
Depends what it is
If that happens, then nobody will doubt the necessity of condoms, who would want to lose that part?
Nah, we`ll cut it off cause it`s a money pit.
always bothers me, the verbiage used to describe the process(es) that occur in micro evolution. The bacteria don't "have a strategy" they don't "develop better weapons systems" nor do they "plan" or "figure out" things. As far as we know it's random chance, changes happen not for a particular purpose or because of a need, but just because changes happen. Bacteria or insects or whatever life form doesn't have a meeting and plan out the strategy they will use to defeat the enemy. They have some members that are slightly different in each of many millions of ways and sometimes some of those ways are significantly better than the others. this is when a species has a genetic bottleneck and afterwards they either completely die off or the new strains repopulate their environments all or most carrying the new traits, where new small deviations start accumulating again for when the next threat to the species happens. sorry to nit-pick but it just seems like our language doesn't have the right words to describe this phenomenon adequately.
+richard reeves How does this sit with you: "Like the evolution of any other organism, bacteria that acquire the toughest, most resistant become more fit -- more adaptable to a range of environments -- and are thus more likely to survive and thrive."
themetr0gn0me yes that works because it doesn't imply it was the bacterium's 'idea' to actively follow some 'plan'.
Cool. That was from the video.
cool some of the time they used good descriptions.
+richard reeves I understand that it bothers you, as a physicist, I also often get a little upset about people using the wrong words when explaining something scientific. But you have to consider that this kind of youtube channels are made for a wide array of different people, not only experts. Since this is the case I can understand that they want to present the topic as colourfull, interesting and understandable as possible. Kinda like a childs book so to speak.
Ive been watching this guy for a long time and i should say, he is changing...
Now my thoughts are running along the line of:
shitshitshitshitshitshitshitshitshitshitshitshitshitshitshitshitshit
We're dead
The plague only killed about a third of the populace, which means you have a 66.667% chance. Better odds if you live in the countryside or are a hermit.
If you have an O blood type, you're not dead from the plague at least!
Thanks so much for this vid it was a big help in my Gr 9 science fse
so, what you are saying is that we need programmable viruses. 3D printers to the rescue!
Johnny Luken I know right!
absolutely 100% fool proof
Deliciousbutter do you mean wont be able to do that for a long time? couldn't is past tense and makes that statement confusing.
I've never taken an antibiotic and I'm super healthy! Yay I'm helping!
Another problem is that very very little work is being done by major drug companies to develop new antibiotics as most companies are more interested in drugs you need to take for the rest of your life rather than 3 weeks as it is more profitable it's really appalling
+Joshua Lansell-Kenny Not to mention the fact that technological research, including medical, is treated as intellectual property. So instead of free-floating in the creative commons for anyone with a bright idea to build off of, any progress being made by a major company can get its plug pulled due to funding problems or the researchers just hitting a dead end, and then spend the next couple years AT LEAST languishing away as the guarded territory of a company doing nothing with it. It's really sickening, and it's why I've decided to go into politics. While America desperately needs people going in to the STEM fields, my talents are best utilized managing the green paper and red tape. I think the general public thinks of lack of scientific breakthroughs in terms of "Not enough smart people having ideas" but the reality is often much more embarrassingly stupid.
+Joshua Lansell-Kenny This is the problem with capitalism, people screw other people over and even themselves just for money.
+Breachi Chan Cancer research is big money, whos to say if a big company funded by charity would tell us if they found a cure for the biggest earning cancers? Its not ethical and a bit macabre but the prevalence of cancer only works to bring in more money for these companies. Making new medicines is not that hard on the grand scale but it does take a lot of time and money, money that investors want to profit from. New antibiotics might be held on to by big companies until there is a massive crisis and they can sell the drugs at a premium to desperate people.
I can see that. Do you have any sources? I want to research this further.
Let's just copy ISIS and brainwash people to murder workers and leaders of those companies then, it's pretty simple.
This guy is my favorite Not-Hank.
Micheal, you are a beautiful fucking swan.
This was a super cool video for me - I'm studying microbiology at Portland State University and to hear OSU come up was awesome! Great job, guys!
Don't worry um... dude? I think you're okay, even though you're not Hank. ;)
(Seriously though, he's alright.)
How does he manage to make bacterial Armageddon sound super cool?
I'm incredibly thankful for my immune system. I VERY rarely get sick any more, even if literally EVERYONE around me (thank you, office job) gets sick. However, if the next black plague is a variation of strep, I'm fucked >.>
You're immune system would be stronger if you got sick more often you realize that?
Blitzertin Should I start licking homeless people in the hopes of getting sick more often?
Butterworthy Go for it! You may even make new friends.
I gotta say I didn't realize the potential issues that might occur when you don't finish your perception. Very informative!
Can you do an episode about the permafrost feedback loop and/or climate change feedback loops in general please?
You seemed more chill than usual in this video. More casual/real..............I really liked the change to be honest.
I have a solution.... an army.... of nanobots that literally fight bacteria.
That's already a thing. Well, kinda. Check out phage therapy.
Go on, just google it. :D
I have a solution. Make a gas that kills all harmful bacterial and does nothing else then release it into the air so that it's all over the globe.
About as reasonable and serious.
Pinkie Pie
YOU'RE A GENIUS! I BET NO ONE ELSE HAS EVER THOUGHT OF THAT! /s
WITH LASER BEAMS AND ROCKET FISTS! PEW PEW! BOOM!
***** Or maybe it was yourself he was as fucking stupid as because he didn't know what the word "harmful" meant. GG, no RE, Hitler.
i love this so much.
*head explodes*
Dear Micheal Aranda, you have an awesome personality for teaching science.
I hate to be THAT guy, but where's Hank
Think about all the projects that Hank manages... he has way more on his plate than I could ever deal with (low stress tolerance...) so if he has to skip an episode once in a while, who are we to complain? Besides, Michael is really cute. ;P
Welp, I'm sufficiently terrified. Thaaaaaanks.
But I know we'll figure something out before the worst happens. Bacteria are smart, but we're smarter.
Please watch this so you can shit your pants in worries, "MUST WATCH On Bacteria Crisis Across America;" at TYT Politics