ฝัง
- เผยแพร่เมื่อ 23 ธ.ค. 2020
- Imagine having the option to get a 3D-printed organ. Well, a team of biomedical engineers from Carnegie Mellon University has just developed the first flexible, full-size, 3D-print of a human heart, bringing us one step closer to that reality.
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Additive manufacturing printers are popular, but are typically known to build hard objects using materials like plastic or metal. But rigid plastic organs aren’t very practical. These printers could be used with softer materials, like biological hydrogels -- you know, to make a heart -- but those tend to collapse mid-print. But this new method can change the game.The 3D-printing technique is called Freeform Reversible Embedding of Suspended Hydrogels or FRESH.
It can print biological structures with soft squishy materials like alginate, a biomaterial made from seaweed, which feels like human tissue. AND it cleverly solves that collapsing problem during print by suspending flexible materials inside a container of gelatin.
For this team of researchers it all starts with a MRI scan from a real heart. The scan gets “chopped-up” digitally into horizontal slices by a program which then translates them into code that a printer will understand. A needle-like nozzle moves through the gelatin support bath, extruding thin layers of alginate. The layers stack on top of each other to build the shape. When the print is complete, it’s put in an incubator overnight, where the temperature is raised to 37°C to gently melt away the gelatin support structure, leaving only the 3D-printed heart.
#3dprinting human heart #health #technology #science #seeker #elements
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The future of bioprinting: A new frontier in regenerative healthcare
www.medicaldevice-network.com...
"Printing body parts may well be the next step in organ transplantation - harvesting stem cells from a transplant recipient and printing them into a replacement organ could help bypass complications associated with organ transplant such as long waits for a suitable donor or immune rejection of the new organ."
Bringing A ‘Ghost Heart’ To Life
www.sciencefriday.com/segment...
"The human heart is one of the most complicated organs in our body. The heart is, in a way, like a machine-the muscular organ pumping about 2,000 gallons of blood in an adult human every day. But can we construct a heart in the lab?"
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Last Christmas gonna hit different once people have 3d printed hearts to actually give and take away
I want lungs
I want lungs , heart , kidney ,
Everything
Lol
🤣
Last Christmas, I gave you my heart….
I would like dental implants myself but I could use a heart replacement.
Becoming a Bionic Commando seems like a reality now.
Stop playing cyber'bug'
Just don’t wear undies and you’re halfway there!
@@danielcisa107 Sorry to hear you have a playststion.
It's just a rubber model... 😂
jpnewpic88.men
As someone with heart problems. This fills me with hope.
How are you?
@@itsneverlupus5544good, how about you?
Teacher: you must help people with a real heart
People with 3D printed hearts:
?
We should also print brains for people who comment “first”
😂😂😂
there is a 1st comment ryt below urs
Every bloody video has an idiot commenting first or the year like we care!!! 🤬😂
Second
Also for people who type in something that was already said in the video, and those pple who ask if anyone still listening in ?
This is what got me interested in biomechanical engineering about 7 years ago for college when the process was in its infancy, I hope I can one day make a contribution to the field and help save lives. Bravo this is what I love to see.
"you might be willing to pay any price"
You know someone is from 'Murican when...
Once I heard an american saying "dying is cheap and easy, advanced brain cirgury is not". Not gonna say he is wrong but profit shouldn't be the focus of the medicine industry, although it's an industry.
@@LUCTIANITO surgery*
@@LUCTIANITO well I mean, when someone spends a decade or more in university honing and learning a highly advanced, very difficult, rare and sought after craft, works in an area that has machines worth tens of thousands, hundreds of thousands, or millions of dollars, and eluded to facility has the hire engineers to perform maintenance on regularly, costs become substantial. Now, the United States is a VERY large landmass with a very spread out population and has to have a very large number of such facilities employing prior mentioned personnel, so it wouldn't be hard to assume that someone would be paying for the facility, specific action, procedures or substance, along with the equipment needed, yes? Universal government provided health care and insurance if scaled to individual facilities on a plus end and mandatory value evaluated and to be provided as a minimum on the minor end would cost the US government horribly if it wants to maintain peak care of advanced facilities and to increase care in those to which are negatively aberrant. It can't without cutting costs. And most countries even with a smaller population and more importantly a smaller landmass (which effects the total number of facilities in most or certain circumstances) can't keep up as well, which is why a term know such as "brain drain" exists, and why the United States receives so many migrants of high vocational background
@@LUCTIANITO you just cursed your own existence with that bs spelling of surgery😂😂😂😂😂😂😂😂🤦♂️
@@reidkrupps3597 of course it would be costly. But the simple fact that we are choosing between lives and cost is ridiculous. No expense should be "too high" to guarantee your citizens decent Healthcare. Expecially considering the budget we use on military and foreign spending.
Haha. She thought she'd have the last laugh when she broke my heart 🙂....
Well, you had to replace it...
Heartbreaking to hear
Awww
Dude, pharmacology is going to be set up in the coming years. Gene editing, Quantum computing, 3D Printed organs with organic similarities. Jeez what am I going to ingest years from now?
Crispr body manipulating pills. I am guessing in 15 years.
Shame that there's a legal option now
*throws away extra hearts*
@Sir 4k would u like one sir?
Barry Harry 216 I’ll take two. Do you have sesame seed buns?
@@waynepooley6950 sure, you also get an extra heart for free
Got any brains? My pet zombies are hungry.
@@magnolia2 yes, take them before 3d printed brains flood the market
Plus the zombies deserve 100% geniune brains
I could see a hybrid...maybe a heart built with collagen but with electronics to mimic the heart's function
That's probably not what is going to happen. The printed heart would probably used as a sort of scaffold to then culture muscle cells onto
@@Aetohatir anything is possible...especially if we start moving to a more bio cybernetic culture
@@Geomaverick124 Indeed. Muscles have to be trained and heart cells are one of the earliest cells created/differentiated in a fetus. So I see what you're suggesting as perhaps the early version or a way to exercise/train the cells, because a weak heart wouldn't help much as a transplant. 😅
Somebody got an artificial heart
@@gamberofritto Jean Luc Picard. 😆
Best part is this may end or at least reduce illegal organ trade
True. The illegal heart thefts have been steadily rising the last few years.
@@Darkmattermonkey77 yep. You can pick from a menu in China
There isn’t illegal organ trade 🤣
@@andreaam805 love idk what world u living in but yes there is.
I'll be immortal
🤣
My step father literally arrived home an hour ago after 3 weeks in hospital and needs to go back for the stent shown here in about a month. Talk about timing.
Merry Xmas.
I hope all goes well. Merry Christmas.
1 year later:
First human skin made by 3d printer
BRO! ITS ALREADY HERE! The made synthetic skin like 3 years ago.
3D printing Dong is where its at bois. Those small PP dudes/bros will be on it at the very first commercial opportunity.
That would be great for burn victims.
@@GalacticallyHatesCorporatism
I want 3D printed foreskins for boys and men.
That is amazing. Great job, Carnegie Mellon University!
Immune system- "I'm about to end this whole molds career."
the 3d printed heart: "im you"
Lmao
It'll probably be printed from your own stem cells, so that shouldn't necessarily be a problem.
@@godlikemachine645 You're talking fantasy sci fi which doesn't exist (& scientists who've tried for 50 years have gotten not far in achieving)! Shutting down conversations about reality of transplant complexity by 'solving' issues with fiction prevents actual progress based on a cultural investment in there still being a problem.
@@andreabarrett878 bruh. Did you even watch this video?
"fresh hearts" is an uncomfortable phrase...
Look darling, i ain't gonna chopping hearts in the field all day Just for You to show up complaining about Bad marketing campaign names...
I like the name it’s great especially if they advertise during the Valentine’s Day 😝
Depends how you grew up
just go to china they have plenty
100th like
As a manufacturing and design student I see this a great breakthrough but as for a side project this is extremely expensive 😅
I love y’all channel please never stop making video 💕💕💕 nobody has these types of video. You guys talk about interesting topics and realistic things as well. It’s a great blend. I’m always learning something new from you guys
Never give up
Feeling heaviness in my Heart while seeing this video.
Anyone else felt same like me ?
4:36 Her face cracks me up! You know that she knows that we know that was a lame joke and I love it. 😆
This is a major step toward the ultimate goal of life. Great job humans!!
Surviving next 50 years would let anyone see so many awesome things like these.
IM GOING TO LIVE FOREVER!
You can say living forever is curse not a bless
@@hufopi7286 not if you can play videogames everyday
Lol
@@phantom66games45 they will get borign
@@jimppa159 nah. It won't. Been gaming for more than 20 years and it ain't getting boring.
Thamk you seeker for bringing amazing new science discoveries and innovations to my attention!
This is so amazing! Your videos always make my day! Thank you Seeker!
:0)
So this seems like it's just a kind of scaffolding for an organ at this point. How does this compare with growing organs from stem cells in terms of which tech is closer to getting a usable organ?
I think the Stem Cells are rather easy to acquire, whereas the natural scaffolding isn't. So they're working on 3D-printed versions. The vessels and nerves would still need to be worked out also. 😅
@@megamanx466 Hmm, so maybe they use this to put stem cells into instead of fully growing an organ on it's own, which I've heard they can only make small versions of. It's all quite confusing to me but interesting.
@@10-OSwords Well heart cells know to beat and will do so when simply touching another heart cells, but they don't know how the whole heart's shape is or how to pump. Researchers found this out after learning how to create stem cells(perhaps before with embryonic stem cells) and so then started down the path of creating a biological scaffold as a frame to "build" a heart on. 😅
I remember the problem with 3-d printed stem cell structures is cells don't stay in the structure form.
Until they can figure out that piece of the puzzle I don't see 3-d printed organs in the near future, or until we get quantum computing......😅.
Excuse my grammar.
O j juice mane 50 bricks youtube😆
Thank you Amanda. Merry Christmas to you.
So all they have to do is make it out of, or at the least just line it with, a conductive material or fiber that allows for contraction and relaxation and there you go, beating heart! Can't wait to see where this tech goes in the next couple decades!
I've had one shoulder and a knee replaced, the other shoulder is next summer....this is interesting in what could be done in the future!
Thanks for the video! Love your channel Excited for developments of the tech. Stay safe. 😁🎄🎁
Ha! No one will be calling me heartless ever again! Victory is mine!
Lmao
Damm that is cold
that story touched my heart
Well here it is! Congratulations 🍾
Crazy to see this now. I remember watching a thing on TV about 3d printed organs back in 2006.
Technology and innovation is moving so fast.
Yeah printing model of heart is real innovation!
We’re in the beginning of a complete new era in human history.
These scientists really seem heart at work!
A similar approach was taken by researchers in Toronto a few years ago, to 3D print organs with stem cells, I believe
Please do a video on the latest advances on 3D printed knees and other joints.
A cool thing you can do is use hard plastic material to create a rigid structure and then use bioplastics to make a flexible material like building your leg you can use the hard plastic as the foot base in the rigid structures and then use the bioplastic for the knee joint ankle and everything else getting one big piece
Can we have more construction and sustainable city/ smart city videos? Please and thank you for all your hard work
So Amazing !
In 2168, there will be 'full-size 3D print of a human body'
Another edit: fully functional with working organs
Another edit: I love drawing
Another edit: I display my art drawings on youtube
Prob 2068
𝚒𝚝'𝚜 𝚌𝚢𝚋𝚎𝚛𝚙𝚞𝚗𝚔 𝟸𝟶𝟽𝟽 𝚊𝚞𝚐𝚖𝚎𝚗𝚝𝚊𝚝𝚒𝚘𝚗𝚜 𝚏𝚒𝚛𝚜𝚝
Black mirror episode in reslity
2050
They need to print some personality
That's fantastic.
so with this can we implant an electric device and make the heart pumping artificially ??
Unfortunately not. Needs to be human cells or a lattice/scaffold that can support them. There has been a successful growing of cardiac cells that spontaneous beat but it's very early stages of the technology.
Amazing!
A great start! 😊❤👍🏻
Mr burns: excellent
Bio printing real human skin on a metal endo-skeleton will soon be possible. Real-life terminators is not a matter of if, but a matter of when.
This is must needed for eye 🙂🙂
This is an incredibly important step but its also as close to having a 3d printed replacement organ as inventing the wheel is to having a race car. It still has a LONG ways to go.
Check out the company Organogenesis, they’ve got a patent and FDA approval for stem cell plasters or ‘bandaids’
Now we need only keep our brains fresh and we can live biologically forever
I love how we humans are evolving
Wow! Hopefully this can be used for organ transplants soon! We're really entering science fiction territory here...
Worth funding🙂
It'll happen, one day we will have the means to insert cells and simply wait and we'll end up with a heart, a heart with vessels and arteries, continueing to grow outward after the hearts grown, we'd probably just snip off the excess arteries and structures that grew at crucial points, swap the heart out and use those same cells around the suture points to allow to regrowth of tissue instead of leaving scars.
Probably not like that but it'll be done. I'll be long dead before then.
In West Philadelphia born and raised in the laboratory is where I spent most of my days
Awesome vid Amanda
Amazing
the method of printing is pretty FRESH.
Can you please cover the new aptera. That's a cool new innovation.
this is heart-tastic news!
“My heart is in the work” -Andrew Carnegie
I wish we could see more medical technology videos. Also diamond batteries
I think it will be more important when we figure out cryogenics. Ability to 3d print cells that would flash freeze in place and be able to combine after thawing. Majority of organs could be replaced, only nerve system remains challenge.
Nice video.
Oh you nailed that last joke....... lol
Imma need a new heart in a couple years. Get on it!
If the gel can support itself you can print from multiple angles, 🧠💥
What about the moving parts like the tricuspid valve? I had a heart infection this summer with damage to my valve and that thing is just 2 tiny flaps that regulates blood flow in only one direction your entire life. Can these 3-D printed hearts do all that?
They can’t yet.
Isn't there already a thing like this? Where they make the template and the use the persons actual heart cells and stem cells to grow the organ
I believe it was in the works, but this seems to be the cheaper & better version/design. 😅
I get Repo Men vibes with this video 🥺
Oh I forgot about that 🤣
I get Scavenger vibes with this video. 😏
YES!
Life expectancy is now 5000 years lol
Hmmmm, a "FRESH heart", does have a certain ring to it :O
aight I'm gonna be on the watch for someone on yt to make a flesh light out of this
love it
Hope you win the HEARTS 💕...
Cant wait to download someone's heart
Feels like human flesh? Hmmmm gonna tell my investors at YouHub
Wow!!!
funny fact, back in 2005ish ive read about 3D printed organs in popular mechanics magazine, I think at barn and nobles store?!, and it had a time when will it will it be a reality, I think it predicted 2025. I told people about it, they looked at me like am crazy, back then.
A human or animal heart isn't only a bunch of organic material in a particular shape and consistency. It's a set of specialized cells that can contract and expand to actually pump the blood. It's not yet clear to me how these 3D-printed models are going to achieve that.
They(these 3D-printed models) are simply the scaffolding that the other parts of the heart adhere to. It's basically one of the final steps in the process to grow a fully functioning heart from "scratch". 😅
Now girls can break my hear several times 😃
I would really love a new printed heart please !
Let’s hurry I’m almost 50 and really need new parts 🙏🙏🙏
everytime Seeker uploads
me: *pog*
Christina Yang finally made History with her research...
Everybody gangsta, till the scientists made a human body
Go go gadget heart!
Immortality
I hope they can print brains...
Thank Yo
Could they use the algenate as a scaffold for human cells to "grow" into?
Thats the plan eventualy
@@superawesomegoku6512 Thanks for the info.
Cant wait to see this on thingiverse :P
i really wanna squish it lmao
well, seeing as a normal human heart is worth upwards of $119k, I'd say $2k is more than absolutely worth it, innit?
Looks like giant gummy bear 😂🐻
This is a fantastic step! In ten years years it will take two hours to make a much more complicated heart to be printed.