Programmable Bacteria: Nature's Most Powerful Tool
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- เผยแพร่เมื่อ 25 ก.ย. 2024
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Twitter: / stephaniesamma
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Credits:
Narrator: Stephanie Sammann
Writer: Ashleen Knutsen
Editor: Dylan Hennessy (www.behance.ne...)
Illustrator/Animator: Kirtan Patel (kpatart.com/il...)
Animator: Mike Ridolfi (www.moboxgraph...)
Sound: Graham Haerther (haerther.net)
Thumbnail: Simon Buckmaster ( / forgottentowel )
Producer: Brian McManus ( / realengineering )
Imagery courtesy of Getty Images
Music:
wonder---no-strings by tristan-barton
nano by evgeny-bardyuzha
the-undertake by borrtex
null by veshza
fall-equinox---alternative-version by the-bows
References:
[1] www.ncbi.nlm.n...
[2] www.nature.com...
[3] news.bbc.co.uk/...
[4] www.pnas.org/c...
[5] faculty.ccbcmd....
[6] news.mit.edu/2...
[7] www.britannica...
[8] www.edvotek.co...
[9] science.scienc...
[10] science.scienc...
[11] www.researchga...
[12] www.nature.com...
Humans: *won't clean up their pollution*
Bacteria: "Jeez, do I have to do EVERYTHING on this planet?"
humans: won't digest stuff in gut
bacteria: guess i gotta do all the shit in here
Some one liked your comment 👍
@@alveolate
human: poops*
Bacteria: I guess I' ve to do all shitty work in here.
@@ruslankazimov622 sad but true & SCARY
Yes
I cant wait for the day that a doctor can say “its just cancer”
that's a really huge and nice statement ...wow!!
"Yeah just pop on over to the chemist and grab the lung cancer pro biotics and come see me inna week" oh how I'd love to see that happen.
@@SimonWoodburyForget you got em in the testys
YES PLEASE
😂😂😂
Mighty TH-cam algorithm, I'm counting on you to recommend me more of these videos.
Subscribing and pressing the bell button might help with that..
@@IlmarKiisk 😂😂
I love how you said "BP Deep Horizon" just to make sure we do not forget who was responsible.
"Aiding the cleanup effort"… as per the narration … the clean up effort (so-called) did very little to mitigate the damage to the coastal dunes, estuaries, shores, shallow waters and deep waters of the Gulf of Mexico. Fishing communities on the Gulf are still being paid not to fish, because the ecological damage up and down the food chain was catastrophic. BP and all the companies that BP outsourced to and forced into cost-cutting shortcuts, basically got away with it. President Obama even obliging with a swim at a local beach while beaches up and down the coast around that particular beach were covered in oil droplets and regular local swimmers were prevented from swimming b/c it caused rashes and breathing issues.
This is amazing! I have a very basic understanding of biology, enough to understand what is being explained. I am so grateful for videos like these that you people make. Thank you!
They are wonderful 😊
There's a mismatch between the images and the narrative that may lead to misinformation. Most of the time the images focus on single-cell organisms that are not bacteria, even though there are bacteria in the background, they're not the focus of the images. When talking about human cells too, there's a bunch of single celled organisms in the screen but no human cell.
Bacteria eating cancer and plastic sounds amazing
All fun and games until the new terrorism is releasing bacteria that eat humans.
All fun and games until that bacteria figures out that it doesn’t just have to eat cancerous cells.
All fun and games till One Party that has nucleair atomic weapons discovered how to modifi nucleair eating bacteria.
Now this Party can use Their atomic Weapons to kill Their Enemy and Cure themselfs with these bacteria.
War won, but at wich cost?
With Covid, I had almost forgotten that cancer is also a thing
Good thing we dont spread cancer to each other
2021: WRITE THAT DOWN, WRITE THAT DOWN!!!
@@aljon5947 😂😂😂😭😭😭
You're not alone, unfortunately a lot of the cancer research has been massively slowed because of funding cuts during covid.
@@aljon5947 We can't spread cancer, but unfortunatly we can spread oncogenic viruses like EBV, HPV... that cause cancer.
All cancer deaths are covid now
My absolute largest concern is how bacteria used to treat people can become pathogenic over time through mutations. But I'm also super excited to read scientific papers about the safety tests!!! And also, I suppose it's a lot easier to cure pathogenic bacteria as opposed to cancer.
Or weaponized
Completely logical and i havent thought of that ngl
@@randimcmillan3148 meh nukes are better and faster
I would be indeed better to understand how cells, like bacteria or Higher complex cells, like Animals, Plants etc. behave or alter in different situations. Everything in our ecosystem is depended on each other to thrive and life. Altering the DNA of bacteria and function by Human modification Sounds like a bad ass cool idea to Cure, for Example Cancer.
But I agree with you that complex of nature and better understanding how nature Works/ Cure disease is not be found in Human modification and altering DNA of organisms.
Cure Cancer? Why not use Science to understand why and how Cancer cells emerge. Would it be Great I've Science could prevent Cancer or diseases?
That's something we will always have to keep up on. Evolution is always moving. It's never static
Love how this started simple then simply explained the complex! I look forward to sharing this with my students.
Just when i was thinking that it has been a while since you last uploaded here
You need more views, good stuff
The stock footage at 5:21 shows ciliates, which are eukaryotes.
Yeah
Yes. Important to draw that distinction
You mean protist?
Thank you @realengineering for sending me here!
This channel has more educational value than my entire school life...
School is useless
@@oliverm1255 for information you use in daily life, mostly yeah. really what it (can and should) be good for is thinking and problem solving skills
Because it is REAL SCIENCE
Not with that attitude, you're just being programmed by a screen.
@@oliverm1255 I learned all this in grade school, yours just blows lol.
This has profound implications for the future. Thanks bacteria, you can be so cool.
Just wait till this tech is abused by some insane government.
For bioengineers that know Python 3:
import bacteria
bac = bacteria.Bacterium()
bac.read(“/home/realscience/bio_code/strain_1.dna“)
while True:
bac.eat()
bac.make_proteins()
bac.replicate()
Bacteria, when magnified, creeps me out! Thank you for making me feel better about it. This piece redefines Spock's favorite word, "FASCINATING!" This narrator has an ADORAvoice. 🧡
Omg same
Wow......thanks for giving such scientific videoes with good production
I've watched this 6 times and it still gives me chill ☣️
I watched a lot of Discovery Channel in the 90s as a kid, so I am innoculated against being excited with miraculous claims of stuff that work on mice, because it seems most treatments available to regular people are pretty much the same as they were back then. Hope I’m wrong
Thankfully, you are wrong about that about cancer. There actually are lots of new treatments available today that weren't there 30 years ago. And thank god for that, my grandma is alive thanks to those new treatments.
There are some new treatments like biological therapy or antibody drug conjugates
@@erilgaz there's also lots of literature showing how all the western world disease epidemics are associated with poor nutrition and other lifestyle factors, but it's mostly nutrition. Meat eating a dairy is strongly associated with HD, several cancers, diabetes and obesity related diseases macular degeneration etc etc. We find compelling evidence in both population studies and clinical trials. many well known US MDs run dietary intervention programs to get people of waiting lists for heart surgery or off diabetes medications under doctor's supervision. But people all want to be able to get cancer and then take a table to cure their disease, that's a condition of a society that preferences individual prosperity over population health and environmental//ecological outcomes.
That “Real Water” thing was kinda funny.
Yeah, I prefer it to that artificial "imitation water"
normal store water is purified tap water
I'm guessing real water is rainwater because oceanwater tastes like ass
i am an engineer watching video at 2:47 AM , yeah just 3 AM thoughts. :)lol
I am watching at 4:10 AM.
You want a cookie? 🤷♂️.
@@MatanuskaHIGH I do. Can you give me one? Chocolate chips included, please.
thank you for the video! very interesting! great job, as always)
can they create "Prions" ( proteins)
when re-heated ( if stored frozen at -70 °C ) and re-activatef inside
the "new host" , and . . . ?!
I'm often warching your videos to learn english. Thank tou for the content, it's very important for me.
*watching *you - but I can't speak Portuguese :)
This Gives new meaning to the old saying "what's gotten into you?"
Don't forget there are numerous Eukaryotic Unicellular organisms too.
You guys are worth 1 million subscribers
Love the quality of these videos 😍
I enjoy your videos so much!
I love this video so much. Thank you for making it and I really love the animation and the production as well as the narrator. World-class work is all I see here!
12:35 Grocery shopping, driving to work, exercise, cooking food.. yes, how in the world do you find the time to do anything else in life?
Holy shit this is awesome
When I was 10, I gave one of my cats the middle name Yersinia, after Yersinia pestis, as I loved learning about pathogens like Yersinia pestis.
TH-cam, u better start recommending useful information like this!
Cancer cell, using mask: don't eat me
Body, without question: alright, I won't
5:21 5:41 Aren't those paramecia (protozoans, i.e. single-celled eukaryotic "animals"), rather than bacteria?
(Just nitpicking about stock footage, great video nonetheless!)
I have to say that thanks for the information I haven't learned that much about bacteria as in this video. Great work!
Great video! One comment though, around 4:00 you started talking about bacteria evolving to eat chitin, i just wanted to clarify that evolution really doesn’t happen until a selection factor causes natural selection, we evolve all the time, in little tiny ways that might be beneficial, harmful or neither!
I hope clinical trials for these kind of bacteria come soon. They can help us solve plastic and air polution.
Good background music.
FANTASTIC! Your channel is fantastic really and I hope that you will make new videos about (Genetics, Genetic Engineering, Microorganisms, Virology, Biotechnology, Epigenetics and others) Thank you so much really.
Hello real science ❤️
I've been seeing your videos for a while now but only today clicked on one and I regret not doing it sooner. Engaging videos and actual references, you certainly live up to your channel name!
Outstanding as usual. And your segue to the sponsorship was seamless - and appropriate. Well done!
Its amazing to think that how these small things are a big part of our lives. Good job micro-buddies :)
Big part of our Lives is a understatement. 😁
All live as we know it, is evolved from single bacteria's. Without bacteria there would be no Animals, Plants, Trees, insects, Sea life, Birds, fungus etc.
Everything in nature would die or excist without bacteria's
But this is not a review of gene-modified bacteria. This is a review of what it's like to live with gene-modified bacteria.
We're surrounded by biodegradable nanites, but we're too stuck in the past to realize it. Every time scientists talk about what nanotech could do I get a little frustrated that genetic engineering is held back so much. Why synthesize a microscopic robot from scratch when nanomachines already evolved billions of years ago? So we can create a new kind of waste?
How did youtube's algorithm took so long to recommend me this diamond star channel ?
Great clip, so much potential!
hey, this is really good! congratulations!
Super high quality videos. Thank you!
Just commenting to boost engagement
These videos are great
Thank you so much for the quality and the knowledge !
In the future, we can "engineer" the bacteria from our gut microbiome to cure anything from aging, depression and etc.. by growing them in our own bioreacter, our gut. We can control the outcomes with nutrient/precursors.
.. and then what?. I fear a dystopian future, an earth ruled by the proxies of bodies in a box, with senescent brains just about keeping things ticking over. A relatively early death, say x4 peak reproductive age, is required. Old uk duffer and curmudgeon here, counting the days :)
@@tim40gabby25 We are guided more by our biological urges. Most societies expect old people just to go to a corner and wait to die.
At that point, we all see through the vanity of life. Some react by turning spiritual, some charitable, and sadly, some request, "Help me die" to all aged care workers. Life is so vain, and yet so precious. Be happy.
Thanks bacteria! I didn't know they did so much to help us :)
Great Narrations!
Some of the simpler things are more tried and true.
A for instance might be producing biofuels with algae and converting plastics into biodiesel.
Even knowledge itself can be a two edged sword.
Be on the lookout, be alert, be wary!
Thank you for sharing great educational videos!
thank you. great channel
As a pharmacist I love bacteria. We use them to produce soooo many different drugs
at this point I am scared of bio weapons and viruses in general
When I get money I will buy my self a bunker 😂
If you wanna see something really cool, Colin Furze built himself a bunker. There’s a TH-cam video on it!
There's a guy on TH-cam who created a tablet by manipulating bacteria and cured his lactose intolerance for 6 months. Yes he tried it on himself.
I mean thats no reason to stop progress, its kinda like saying we should ban knives because they could be used to hurt people
Similar to how if we could forge knifes then we likely could forge shields, if we have the tech to manipulate microorganisms into bio weapons, then we also likely could use the same tech to create treatments vaccines and cures.
I hope that helps somewhat
Nukes are likely weapons used instead of bio weapons, just because bio weapons are easily identifiable, and could be potentially trackable
I like how some people are germophobes when the moment you finish washing or sanitizing your hands, germs immediately go on your hands without you knowing
Are we using CRISPR for the genetic programming or something else?
Watching it for the great content - listening to it for the voice.
I have something called a "Milwaukee Tumor." Its from too much beer (old people will know that most US beer used to be brewed in Milwaukee)
Great video; thanks! 😃
Thanks!
Mechanics use a special tank and pump with bacteria in it to clean grease or oil covered tools as the bacteria break it down
Discussion about bacteria? Lacto bacillus...enters the chat.
Narrator voice is so calm
great video as always!
Some other TH-camr who does this in a professional manner (Californians Shoot me now) Modified baker's yeast to produce Beta Carotene. He then mixed it in with the Unmodified baker's yeast. The result was a Vitamin rich bread.
Wow, just WOW!
""NOW THE TABLES ARE TURNING AS WE LEARN TO GENETICALLY PROGRAM THEM....................""
OOOOOH THE HUBRIS..............
THANK YOU!!
fascinating
I love this planet so much ❤️🌎
I don't know that ,I have to give like or dislike on this comment 😋😁
I wonder what would happen if the bacteria further evolved after being modified for a different intention. Like if u gave someone bacteria to consume cancer and then it adapted to consume good cells as well once cancer cells were gone
A plastic eating bug - what could go wrong?.. cautious old uk duffer here, checking my drinking cup for holes..
Honestly when bacteria eventually evolve to more efficiently decompose plastics and fossil fuels human civilization might just permanently revert a few thousand years.
One of my favourite channels
Can we take a moment to appreciate that this is FREE 😘
You are right this is my favorite channel 🙂
Thank you for sharing this!☺️
One of my favorite uses of bacteria is to convert fish poop into food for the plants in my aquarium which then produces oxygen inside the tanks which allows the fish to survive without the need for a aerator or filter.
another fascinating thing is that it appears life can concoct an enzyme to do anything it wants.... maybe eating plastic is just the beginning
She's talking about immune checkpoint inhibitor named Nivolumab at 10:40
Well, as long as we don't create a monster that ends up devastating us, or even wipe us out.
The biological equivalent to grey goo. Tiny machines that just eat and replicate.
For all mice that are watching, living and being disposed of in a lab is not a normal life, so do try to escape.
Ha. Give us a key
Bacteria is why oxygen became usable & necessary for plants & animals when before that it simply used to not allow life molecules to form.. which it does in our body to an extent, that's why we take antioxidants
The bit on cancer brought tears to my eyes. We really have come far as a species 👌🏾
I hope scientists don't fuck up playing with this and cause bacteria to fuck up human beings
Can you make a video that goes in detail about genome editing?
Do yeast next please! They are also very modifiable and can be very usefull
I Love Bacteria, they were so underated, they help us without even us knowing it,
That's great
amazing!!
So cool!! What an awesome channel
Love the work that you do on this channel keep up the great work thank you!
Anyone else notice the narrator's weird cadence and stressing of words at random points in the sentence? Felt like listening to a third-grader reading aloud during literature class