Well done Dr Majid. LigTMap is good for two bacterial species if you found online tool that predict multiple bacterial targets please share that as well.
@@MajidAli2020 frome 3:50 you showed many compounds , how can we treat them ? And how can we use it ? Are these molecules are the one to slect before doing a docking? And how to select them?
Sir actually I was trying to do in pyrx the problem is with the ligand structure, it's a derivative of benzotriazole we are trying but the structure is not available from pubchem
Great, superb Dr.
👌👍
If confidence level in possible Target higher than conference level direct target which one i use please answer sir
Well done Dr Majid. LigTMap is good for two bacterial species if you found online tool that predict multiple bacterial targets please share that as well.
Sure
Sir, What to do? If my target is not protei or enzyme. My target is Lipid II and Lipid I? How to predict the activity
👌👌
Thank you , can you please explain the part of multi molecules that you had shown using swees adme , what do you mean by slecting it ?!
I cannot understand ur question
@@MajidAli2020 frome 3:50 you showed many compounds , how can we treat them ? And how can we use it ? Are these molecules are the one to slect before doing a docking? And how to select them?
@@ajyui847 yes we will predict target for our desired compound before docking
@@MajidAli2020 I got that , but what about the many conformers ?
Sir can we calculate the IC50 value of drug without experiment, but with software, please make a video on
We cannot calculate IC50 value without experiment. IC50 value of already known drugs against certain target can be found in the literature
Ok sir, thanku for the clarification
Sir can you make a video on x -score software for redocking ❤️
Sir can we download 3d structure from molinspiration
For what purpose?
@@MajidAli2020 sir actually we have a project work, we have to carry out docking for that purpose
@@harithak5102 For docking purpise you can make structure in Chemdraw or use discovery studio.
Sir actually I was trying to do in pyrx the problem is with the ligand structure, it's a derivative of benzotriazole we are trying but the structure is not available from pubchem
And we really don't know about docking we trying to do with the help of some you tube vdo😅
Assalamu alaikum sir
Is there any opportunities to work in your drug related project or research online?
Why not sure
Sir, What to do? If my target is not protei or enzyme. My target is Lipid II and Lipid I? How to predict the activity