HPLC | High performance liquid chromatography

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  • เผยแพร่เมื่อ 8 ม.ค. 2025

ความคิดเห็น • 352

  • @artemiskar1897
    @artemiskar1897 4 ปีที่แล้ว +790

    youtube once again helping more than the university instructors

  • @ArtuursPaulausks
    @ArtuursPaulausks 3 ปีที่แล้ว +154

    Well, as a guy who daily works with HPLC have to say video is very good for brief introduction. Obviously HPLC is more complicated, with much more details. Just want to give shout out to all chemistry students and tell them to not be afraid of HPLC. In most cases, it is easy to develope a method on HPLC to determine some kind of compound, it might take just a few tries to make sure your compound of interest is separated from rest. Just always remember to filter your samples using 0.45 um filters and inject clean samples, also use guard columns :)

    • @TrangNguyen-nw9dq
      @TrangNguyen-nw9dq 2 ปีที่แล้ว +2

      Dear, It is grateful when I read your comment. Could you suggest some videos which relate to developing method analysis on HPLC. I am a student who is learning HPLC to support for Master's and phD courses. Therefore, I appreciate if you could support me. Thank you so much.

    • @animaluveteranu9523
      @animaluveteranu9523 2 ปีที่แล้ว

      don t forget to mesure you r standards corectly and shake them on ultrasonyc device It happends to my colegue and he finds out after 3 days XDDDD but I have a question for you if you work on hplc are you working on spectofotometers that use uv light?

    • @ArtuursPaulausks
      @ArtuursPaulausks 2 ปีที่แล้ว +1

      @@animaluveteranu9523 UV/VIS thermo Dionex Ultimte

    • @冯玲巧
      @冯玲巧 ปีที่แล้ว +1

      Hi there, your latest post about hplc really caught our attention. We are the manufacturer of hplc and have 20 years experience, if you are interested, provide an email address and we can send you the case study proposal.

    • @helmetongrass1893
      @helmetongrass1893 ปีที่แล้ว +1

      hey, uhh.... can you please tell me if he said absorbent or adsorbent material? I mean when he is talking about the material in the column...
      1:34 Edit: Nevermind, it's adsorbent material

  • @nbent4607
    @nbent4607 2 ปีที่แล้ว +15

    Real-life heroes don't wear capes, a man once said.
    Thanks a lot!

  • @cioccolatamania3622
    @cioccolatamania3622 10 หลายเดือนก่อน +5

    Thanks!!
    I am truly amazed by chemists and engineers that develop these analytical instruments

  • @srenathganesan
    @srenathganesan 3 ปีที่แล้ว +31

    Awesome explanation. No need to search for any other topic. Its a complete combo package.
    Thank you very much for making such a video.....

  • @CM-yp2hg
    @CM-yp2hg ปีที่แล้ว +331

    Here cuz I lied on my resume

    • @haven3911
      @haven3911 8 หลายเดือนก่อน +3

      How’d it go?

    • @CM-yp2hg
      @CM-yp2hg 8 หลายเดือนก่อน +34

      @@haven3911
      It actually went really well. It’s not that I have no idea what an hplc is but I was not proficient enough to put it down in my resume by any means. I didn’t get that particular job but I applied to a few other and within a couple of weeks I became an analytical chemist and I am very well proficient in it now :)

    • @sinchanakr6156
      @sinchanakr6156 8 หลายเดือนก่อน

      Hey can you help me

    • @NavjotSingh-uq7tc
      @NavjotSingh-uq7tc 6 หลายเดือนก่อน

      Me as well

    • @akezelb7166
      @akezelb7166 6 หลายเดือนก่อน +13

      Fake it until you make it 😊.

  • @rachmadamayanti1858
    @rachmadamayanti1858 3 ปีที่แล้ว +42

    Wow, a really great explanation! If this video was launched during my college time six years ago, I would have been a great Chemist who confident about using HPLC.

    • @冯玲巧
      @冯玲巧 ปีที่แล้ว

      Hi there, your latest post about hplc really caught our attention. We are the manufacturer of hplc and have 20 years experience, if you are interested, provide an email address and we can send you the case study proposal.

  • @akezelb7166
    @akezelb7166 6 หลายเดือนก่อน +2

    I am chemist with 7 year experience in Chromatography and this course is very useful simple clear and straightforward. Good job 👍

  • @daanstrik4293
    @daanstrik4293 ปีที่แล้ว +8

    Currently working on my internship report and needed a quick refresher. This video has been one of the most time efficient summaries i've found.
    Cheers!

    • @冯玲巧
      @冯玲巧 ปีที่แล้ว

      Hi there, your latest post about hplc really caught our attention. We are the manufacturer of hplc and have 20 years experience, if you are interested, provide an email address and we can send you the case study proposal.

  • @shinchanshinchan9155
    @shinchanshinchan9155 2 ปีที่แล้ว +2

    Thank you so much sir it's really a clearcut explanation i can't believe this almost a huge explanation is covered in 7mins 36sec

  • @wiggywoman5184
    @wiggywoman5184 3 ปีที่แล้ว +10

    thank you for this video! i'm in a biochem grad program but coincidentally never took an actual biochem in undergrad, so these videos are helping a lot!

  • @Richard-kz1ee
    @Richard-kz1ee 3 ปีที่แล้ว +6

    This video is a life saver. Thank you very much . Importantly, I have subscribed to this channel.

  • @mangosorbet8183
    @mangosorbet8183 2 ปีที่แล้ว +1

    This TH-cam helps me more than my teacher in the college.

  • @claudiosaitta3124
    @claudiosaitta3124 3 หลายเดือนก่อน

    Thank you very very much! after many years of study I finally can say I really, deeply understand HPLC

  • @cozmos3678
    @cozmos3678 ปีที่แล้ว +3

    Brief and clear explanation... Thank u❤️

  • @celebritystylewatch
    @celebritystylewatch 4 ปีที่แล้ว +9

    Explaining amazingly giving maximum concepts

  • @baskarang7618
    @baskarang7618 2 ปีที่แล้ว

    Within 2 hrs I have my xam. It's a 💎 for last min preparation
    .
    ..

  • @கவிநிலா
    @கவிநிலா 10 หลายเดือนก่อน

    Thank you so much..With in a short time you've explained all the basic things in a wonderful manner with the help of drawings.

  • @anamariatorres6917
    @anamariatorres6917 2 ปีที่แล้ว +1

    The best explanation of HPLC. Thank you so much

  • @aryanshah1943
    @aryanshah1943 4 ปีที่แล้ว +20

    perfect explanation, thank you!

  • @iroshasanjeewani6080
    @iroshasanjeewani6080 2 ปีที่แล้ว +1

    Absolutely ,This was helped me to undestand about HPLC.Thank you ❤.

  • @hope2633cu
    @hope2633cu 2 ปีที่แล้ว +3

    Awesome really we are learning a lot freely. Thank you so much

  • @chemvibes28
    @chemvibes28 6 หลายเดือนก่อน

    It's truly very helpful to me. I am learning from this just before my exam. Lot's of love from India ❤🇮🇳

  • @LinitedfiA
    @LinitedfiA 3 ปีที่แล้ว

    Lmao. I still did’t get it why my class need 8hour to explain HPLC instead of 10 min. Good work btw really appreciate your work ,very helpful for overview.

  • @jhansilanka1869
    @jhansilanka1869 5 ปีที่แล้ว +4

    Excellent explanation i undertood very easily

  • @setupatel1476
    @setupatel1476 ปีที่แล้ว +9

    Back ground music is not needed ,,it disturb the understanding

  • @DawidFRF
    @DawidFRF 2 ปีที่แล้ว +1

    My phone fell off and that's why I'm here, I've always been curious how the experiment I had in my physics class worked 🥰🥰 thanks for that

  • @livesteps3384
    @livesteps3384 3 ปีที่แล้ว +3

    described very well.Understood the content clearly.Thank you very much.Plz do more clear lessons.

  • @iddah3732
    @iddah3732 3 ปีที่แล้ว +4

    Very well explained. I can now answer any question in HPLC with ease.thank you

  • @Hozanaa
    @Hozanaa 8 หลายเดือนก่อน

    Thanks, it was very clearly explained and specific. Neat diagrams and good presentation. Easy and not messy ❤

  • @ELICE6
    @ELICE6 3 ปีที่แล้ว +3

    Great video and very simply explained.Thank you so much!

  • @sashansachinda9812
    @sashansachinda9812 5 ปีที่แล้ว +12

    superb clearly understand

  • @42najibshaikh98
    @42najibshaikh98 3 ปีที่แล้ว

    It's just awesome. Shorter video , better explanation.

  •  หลายเดือนก่อน

    Thanks for this amazing video! Everything was clear!! 🎉❤

  • @ulamgnuszewska
    @ulamgnuszewska 6 หลายเดือนก่อน

    now I understand! You're a great teacher :)

  • @alphynisasteaphen282
    @alphynisasteaphen282 3 ปีที่แล้ว +2

    thank you for such excellent explanation

  • @vig7095
    @vig7095 4 หลายเดือนก่อน

    Once again, an Indian guy saving my grades 2 days before my Chemistry Test.

  • @amrayyad5897
    @amrayyad5897 4 ปีที่แล้ว +66

    here with a typical night of due paper in post-grad after not knowing anything about chemistry for the last 3 years

  • @drashtidarji
    @drashtidarji ปีที่แล้ว +1

    Amazingly explained!! 😍👍

  • @anikislam8507
    @anikislam8507 5 ปีที่แล้ว +8

    love this channel. from bangladesh.

  • @militarybrat123
    @militarybrat123 4 ปีที่แล้ว +20

    Osmm it's enough for exam . 🔥

  • @sabinahasanova7198
    @sabinahasanova7198 2 ปีที่แล้ว +1

    SO SIMPLE AND INFORMATIVE! THANK YOU

  • @TechsScience
    @TechsScience 2 ปีที่แล้ว +2

    Very well explained 👏
    Thanks for this video

  • @sirtintly390
    @sirtintly390 4 ปีที่แล้ว +55

    This was just randomly recommended to me. I don't even know what this is.

    • @nk_17
      @nk_17 3 ปีที่แล้ว

      Lol🤣🤣🤣
      I wish this was recommended to me earlier ...😂

  • @MB-vd6hc
    @MB-vd6hc 5 ปีที่แล้ว +15

    that was awesome, thanks sir.

  • @AS-zf4nj
    @AS-zf4nj 3 ปีที่แล้ว +2

    You're the real MVP.

  • @christophergoudarzi9992
    @christophergoudarzi9992 ปีที่แล้ว +1

    Great video as always, thanks so much!

  • @MonkClasher
    @MonkClasher 2 หลายเดือนก่อน

    Nice. It's easy & simple to understand ❤

  • @aprajita629
    @aprajita629 4 ปีที่แล้ว +1

    Thank you so much. Very nicely explained with animation & way u speak. Plz keep it up.👍👍👍

  • @dilshanchathuranga6962
    @dilshanchathuranga6962 ปีที่แล้ว

    Thank you very much . This video was very useful for my exam❤️

  • @roroiyaka
    @roroiyaka 3 ปีที่แล้ว +1

    very helpful, thank you for making the video. much appreciated

  • @chennamsettiprasad7257
    @chennamsettiprasad7257 ปีที่แล้ว

    What ye class explanation,,great video

  • @NannannanSJN
    @NannannanSJN 4 ปีที่แล้ว

    Thanks for video. It helped me to understand HPLC!!

  • @tanvirahsan5775
    @tanvirahsan5775 3 ปีที่แล้ว +3

    Outstanding, Thank you ♥️

  • @mahakrathod8679
    @mahakrathod8679 3 ปีที่แล้ว +1

    Best video on HPLC

  • @shirinmittal3225
    @shirinmittal3225 2 ปีที่แล้ว +1

    Very nice explanation. Thank you

  • @pepelaugh5825
    @pepelaugh5825 4 ปีที่แล้ว

    Really really thank you for the video
    The very best explanation

  • @pharmaboy1510
    @pharmaboy1510 3 ปีที่แล้ว

    Love this Channel From Bangladesh

  • @varunkibett5955
    @varunkibett5955 6 วันที่ผ่านมา

    Informative piece 😊

  • @jacktam5855
    @jacktam5855 4 ปีที่แล้ว

    You saved my life. Thanks man

  • @rowidakhalily5760
    @rowidakhalily5760 11 หลายเดือนก่อน

    Awesome explanation,Thank you so much

  • @AA-gl1dr
    @AA-gl1dr 3 ปีที่แล้ว +1

    Excellent video, thanks!

  • @DeniseP
    @DeniseP 2 ปีที่แล้ว +3

    Size exclusion 5:55 Ion Exchange 6:22

  • @iannalins2369
    @iannalins2369 3 ปีที่แล้ว

    this video helped me so much for a apresentation, thank you so much!!!

  • @btsforever5123
    @btsforever5123 3 ปีที่แล้ว +1

    Tq so much sir it's easy to exam preparation😇

  • @Ocyon
    @Ocyon 3 ปีที่แล้ว

    Good video! Thanks for that :) Cheers from Germany

  • @shabinmillet9261
    @shabinmillet9261 ปีที่แล้ว

    explained very clearly and nicely

  • @Serwada237
    @Serwada237 ปีที่แล้ว

    The best lecture here

  • @ahmadhamza6618
    @ahmadhamza6618 4 ปีที่แล้ว

    Best vedio to understand hplc

  • @Lia_liah
    @Lia_liah 3 ปีที่แล้ว

    Thank you for the vedio and by this vedio i understood the topic very clearly

  • @priyankapriyadarshini8308
    @priyankapriyadarshini8308 2 ปีที่แล้ว

    It was very much helpful 🤩🥳🥳

  • @anchorsreyashi
    @anchorsreyashi 3 ปีที่แล้ว

    Very nice explanation...thank you

  • @scimathlab197
    @scimathlab197 3 ปีที่แล้ว +4

    tHANK YOU SO MUCH FOR THIS SHORT INFO!! SO USEFUL AND HELPFUL!BINGO!

  • @Vaibhav............
    @Vaibhav............ 4 ปีที่แล้ว +1

    Best explained ever tysm♥️♥️♥️

  • @samuelbabalola3479
    @samuelbabalola3479 3 ปีที่แล้ว +1

    This was super helpful!

  • @martinnrrekjrgrndahl3715
    @martinnrrekjrgrndahl3715 4 ปีที่แล้ว +3

    Nicely done introduction to the subject. Feel a little more confident next time I am applying for a job mentioning this technique.

    • @nk_17
      @nk_17 3 ปีที่แล้ว

      You got the job?

  • @romulo7961
    @romulo7961 หลายเดือนก่อน

    Curso terrível que eu escolhi pra minha vida

  • @ahmadfares5243
    @ahmadfares5243 3 ปีที่แล้ว +1

    Simple and clear thank you 😊

  • @esraaalmasoudy4630
    @esraaalmasoudy4630 4 ปีที่แล้ว +1

    This was helpful. Thank you sir.

  • @gandhamgracy4937
    @gandhamgracy4937 3 ปีที่แล้ว +1

    Easy to understand 👍🏻

  • @myworldofinstrumentation6523
    @myworldofinstrumentation6523 3 ปีที่แล้ว +1

    Helpful information

  • @MayankSingh-uj6hi
    @MayankSingh-uj6hi 5 ปีที่แล้ว +1

    Really awesome videos

  • @shaikabdullah..
    @shaikabdullah.. 4 ปีที่แล้ว +1

    Good explanation

  • @shivaramsmjadhav3298
    @shivaramsmjadhav3298 5 ปีที่แล้ว

    Love u & thanks ur making very good vedio ....I'm ur new subscriber from India biochemistry student

  • @vsilvia1906
    @vsilvia1906 3 ปีที่แล้ว

    I love your videos thank you so much!!!

  • @nurilazizah260
    @nurilazizah260 3 ปีที่แล้ว

    Thank you very much. nice explanation :)

  • @Abdulkader-sq3qo
    @Abdulkader-sq3qo 2 ปีที่แล้ว +1

    Very well described.

  • @HarukaKaku-l7p
    @HarukaKaku-l7p ปีที่แล้ว

    I like this video so much. If you don’t mind, I’d like to ask your permission to share this video to the other website in China for the embarrassing reason that TH-cam is blocked form accessing in China. Of course, I’ll give sources of the original website. Thank you so much.

  • @_archana_4147
    @_archana_4147 3 ปีที่แล้ว +1

    Superb!!! 🙌

  • @samueld77
    @samueld77 3 ปีที่แล้ว +1

    Great video

  • @hafizghaniullahsafi6853
    @hafizghaniullahsafi6853 3 ปีที่แล้ว +1

    Well explained 🧡

  • @casper2917
    @casper2917 4 ปีที่แล้ว +1

    Thanks for the explanation

  • @hussainsaleh389
    @hussainsaleh389 2 ปีที่แล้ว

    Very great explanation my dear

  • @enumahchinweoke127
    @enumahchinweoke127 4 ปีที่แล้ว +3

    Explain more on the polar and non polar and what they got to do with the phases?
    Thank you!!

    • @michaelberman3648
      @michaelberman3648 4 ปีที่แล้ว +7

      Briefly, a more polar molecule indicates that there is a net negative charge on one side of the molecule and a net positive charge on the other side of the same molecule. And the net negative and positive charges are dispersed over a specific region location of the molecule. But keep in mind that the more "polar" a molecule is, the greater the separation of positive and negative charges exist on the same molecule. For example, a non polar molecule would be carbon dioxide or benzene because there is complete symmetry because carbon dioxide is not bent but is straight and the regional negative charges on the two oxygen atoms connected to the carbon atom cancel each other out to form a net zero dispersed negative charge. Likewise, the benzene molecule is flat and symmetrical as well. On the other hand, water is a bent molecule so the dispersed net negative charges on the two oxygen atoms result in a net negative dispersed charge on one side of the molecule and because the electron negative charges migrate more towards the two oxygen atoms, the result of this is that there is a net positive charge on the other side of the molecule where the hydrogen atom is located. Thus water is a very polar molecule. And also remember that in all forms of chromatography, one should always keep in mind that "like dissolves like". Meaning that in general, a polar solvent will dissolve a polar solute or molecule of interest to analyze. And a non-polar solvent will dissolve a non-polar solute. For example, all salts are polar so a polar solvent such as water will dissolve a salt which is a polar solute because salts have a distinct positive charge on one side of the molecule and it has a distinct negative charge on the other side of the salt molecule. On the other hand, a non-polar solvent liquid such as benzene will dissolve a non-polar solute molecule such as carbon tetrachloride, hexane and many other relatively non-polar solutes as well.

    • @kdhasdgv
      @kdhasdgv 4 ปีที่แล้ว

      @@michaelberman3648 Thank you so much

  • @claudiaatsu1056
    @claudiaatsu1056 3 ปีที่แล้ว +8

    That is a very good explanation! Thank you, is there any paper that you suggest that explains the function of HLPC? In order to detect vitamin K with the technique of HLPC, is there only that procedure or is a combine procedure with another technique? Thanks

  • @cheneecleveland4588
    @cheneecleveland4588 3 ปีที่แล้ว +1

    Very helpful review!

  • @abdulrahman-ob5wx
    @abdulrahman-ob5wx ปีที่แล้ว

    Thank you soo much for helping us

  • @narmeenfatima5145
    @narmeenfatima5145 6 หลายเดือนก่อน

    thanks alottt it was very helpful

  • @EnglishExcel2208
    @EnglishExcel2208 5 ปีที่แล้ว +1

    Nice xplanation

  • @thewwefan57
    @thewwefan57 4 ปีที่แล้ว

    That minecraft noteblock beat at the end tho, lit