Sensitivity and Specificity Explained Clearly (Biostatistics)

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  • เผยแพร่เมื่อ 5 มิ.ย. 2024
  • Understand sensitivity and specificity with this clear explanation by Dr. Roger Seheult of www.medcram.com/?Y...
    Includes tips on remembering the differences between true positive, true negative, false positive, false negative, and other statistics, as well as the overall effect on clinical lab values. This is video 1 of 1 on sensitivity vs specificity.
    Speaker: Roger Seheult, MD
    Clinical and Exam Preparation Instructor
    Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
    MedCram: Medical topics explained clearly including: Asthma, COPD, Acute Renal Failure, Mechanical Ventilation, Oxygen Hemoglobin Dissociation Curve, Hypertension, Shock, Diabetic Ketoacidosis (DKA), Medical Acid Base, VQ Mismatch, Hyponatremia, Liver Function Tests, Pulmonary Function Tests (PFTs), Adrenal Gland, Pneumonia Treatment, any many others. New topics are often added weekly- please subscribe to help support MedCram and become notified when new videos have been uploaded.
    Subscribe: th-cam.com/users/subscription_...
    Recommended Audience: Health care professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NDBE, RN, RT, MD, DO, PA, NP school and board examinations.
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    Produced by Kyle Allred PA-C
    Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical educational and exam preparation purposes, and not intended to replace recommendations by your health care provider.

ความคิดเห็น • 125

  • @kirstenroche8160
    @kirstenroche8160 3 ปีที่แล้ว +32

    I have tried to learn this concept about 100 times in medical school. It never made sense to me. Your one short video talking about cars has somehow completely driven this concept into my mind! Thank you SO MUCH!

  • @alphavirginis260
    @alphavirginis260 5 ปีที่แล้ว +4

    This is, by far, the best explanation of Sensitivity and Specificity! Thank you!

  • @MuhammadJunaidAshraf
    @MuhammadJunaidAshraf 4 ปีที่แล้ว +4

    I have an exam in a week and I couldn't understand the the SPIN and SNOUT thing so I searched Sensitivity and specificity explained intuitively and this came up. Not disappointed, it explained so much. Thank you.

  • @pcookieness
    @pcookieness 7 ปีที่แล้ว +8

    Speaking my language, you used the perfect examples and methods to teach this!

  • @cili5724
    @cili5724 3 ปีที่แล้ว +7

    OH MY GOSH this actually makes sense finally! As I write boards, here I am
    Once again trying to learn this! Thank you! You’ve done it!

  • @brianjackson4177
    @brianjackson4177 7 ปีที่แล้ว +1

    All of your videos are great. They are concise, well planned, and effectively communicate the concepts! Thank You!

  • @RohanKayani
    @RohanKayani 4 ปีที่แล้ว +3

    Beautifully explained. A must know lecture before reading medical research articles.

  • @burakORAKC
    @burakORAKC 9 ปีที่แล้ว +8

    this was fab thank you so much. Your title is just what I found in the video "EXPLAIND CLEAR" meaning we have a true-positive (TP) :D

  • @SubhabrataMoitra
    @SubhabrataMoitra 7 ปีที่แล้ว +23

    Brilliant explanation. Could you make a video on sensitivity and specificity with a real-time example? A drug-disease interaction would be great.

  • @annetteasbury7415
    @annetteasbury7415 9 ปีที่แล้ว +1

    Wow, you made it so much easier to understand than our professor. Great use of the analogy of the car alarm. Thank you!

  • @jcleach2764
    @jcleach2764 2 ปีที่แล้ว

    This was by FAR the best breakdown and explanation I've come across. Thank you!!

  • @ORagnar
    @ORagnar 4 ปีที่แล้ว

    Thanks for this video from 6 years ago. What makes this concept clear is to realize that there is noise you're trying to contend with.

  • @victoriacarter9892
    @victoriacarter9892 8 ปีที่แล้ว +2

    Amazing as always! Your videos take difficult concepts and make them very simple and easy to understand. I absolutely love your channel. Thanks for doing what you do! :)

    • @Medcram
      @Medcram  8 ปีที่แล้ว +1

      +Victoria Carter Thank you for the feedback!

  • @toddmason1865
    @toddmason1865 9 ปีที่แล้ว

    Excellent video from an excellent physician. I worked with Dr. Seheult for several years and I can say he definitely knows his stuff and has a great voice and ability to explain clearly, no doubt. Thank you doctor it helped immensely.

    • @Medcram
      @Medcram  9 ปีที่แล้ว

      Todd Mason Thank you Todd, great to hear from you

  • @saraamin8154
    @saraamin8154 10 ปีที่แล้ว

    Thank you :) ! You always have wonderful explanations.

  • @MrKoolguy9
    @MrKoolguy9 7 ปีที่แล้ว

    Excellent explanation with lucid examples ... awesome !!!

  • @user-om9jv9om8f
    @user-om9jv9om8f 8 ปีที่แล้ว +3

    Yes, it's really clear in explanation. Thank you so much!!

    • @Medcram
      @Medcram  8 ปีที่แล้ว +1

      為主作工 good to hear- thank you

  • @pohsstudio7769
    @pohsstudio7769 10 ปีที่แล้ว

    Great analogy with the car, makes it so much more simpler!

  • @mateuszkaczmarek9848
    @mateuszkaczmarek9848 3 ปีที่แล้ว

    Best video on sensitivity and specificity, great job!

  • @cortis77
    @cortis77 10 ปีที่แล้ว

    This is the best video I could find explaining sensitivity and specificity clearly, THANK YOU!

  • @Bekah07
    @Bekah07 10 ปีที่แล้ว

    This is fantastic.. thanks so much. When is the next video in the series going up?

  • @jakirhossain8409
    @jakirhossain8409 10 ปีที่แล้ว +3

    a lot of thanks
    you make the things so easy

  • @salam7905
    @salam7905 2 ปีที่แล้ว

    that car example has clarified everything I was confused about .. thank you so much ^-^

  • @radwaandjama923
    @radwaandjama923 3 ปีที่แล้ว +3

    You sir are an absolute legend. Couldn't't have explained it any better. Thank you!!

  • @nichols44nancy
    @nichols44nancy 10 ปีที่แล้ว +1

    great video...hope you will go on to part 2 :)

  • @moe1n
    @moe1n 9 ปีที่แล้ว

    Excellent. after many years I got my answer. Thank you .

  • @AjaySharma-pg9cp
    @AjaySharma-pg9cp 6 ปีที่แล้ว +2

    Explanation provided is quite good

  • @saileshbalanagu7530
    @saileshbalanagu7530 6 ปีที่แล้ว +1

    Thank you so much! Its very clear now.

  • @DrMilanii
    @DrMilanii 10 ปีที่แล้ว

    Great video! Can you please explain IV fluids in clinical practice? Thanks a lot

  • @ankursatya4733
    @ankursatya4733 7 ปีที่แล้ว +1

    Quite explanatory and the car example was chosen "specifically".

  • @DeepBlueMuslim
    @DeepBlueMuslim 8 ปีที่แล้ว

    Thank you, simple explanation for what is a relatively difficult concept. Think i struggled due to my understanding of the words 'specific' and 'sensitive'

    • @Medcram
      @Medcram  8 ปีที่แล้ว

      +Omer Elhassan Thank you for the feedback

  • @terigopula
    @terigopula 5 ปีที่แล้ว

    That was a nice explanation. Cheers! :)

  • @Mrseabase1
    @Mrseabase1 8 ปีที่แล้ว +1

    Thank you for the video. It was helpful.

    • @Medcram
      @Medcram  8 ปีที่แล้ว

      Glad it was helpful - thanks for the comment

  • @petesburgher
    @petesburgher 5 ปีที่แล้ว +1

    thanks for the explanation ... I get it now!

  • @bodybalanceanneloes9666
    @bodybalanceanneloes9666 ปีที่แล้ว

    Thank you for this great explanation!

  • @ericlipnack4175
    @ericlipnack4175 5 ปีที่แล้ว +1

    thank you, great explanation

  • @badr985
    @badr985 9 ปีที่แล้ว +7

    where is the second video for the mathematical interpretation part ?

  • @b.kwanmin3367
    @b.kwanmin3367 5 ปีที่แล้ว +1

    This is brilliant !

  • @bobolob
    @bobolob 8 ปีที่แล้ว +3

    Helpful, but when you got to the bell curves, it was hard to visualize TP/FP and TN/FN because you didn't actually label them under the curves. If that makes any sense. You filled the spaces in, just no labels.

    • @DreamEclipse
      @DreamEclipse 5 ปีที่แล้ว

      That's because it's very hard, he would have to draw it three times. But for reference, if the test is equally sensitive and specific (point B), the half of the curve on the left is the TN, the half of the curve on the right is the TP, and the bisecting part in the middle from left to right is the FN and FP.

  • @nothodube3698
    @nothodube3698 6 หลายเดือนก่อน

    Great stuff. Simplified👌

  • @00bean00
    @00bean00 3 ปีที่แล้ว +2

    The interpretation I made:
    Spec. is the number (or %) of negative cases it _accurately_ rules out. (Negatives)
    Sens. is the number (or %) of cases it accurately _identifies_ . (Positives)
    Thus, for any given test there will be a gap (or %), which is the number of cases that cannot be accurately known, or, are _unknowable_ (as FP or FN).

  • @nazmaahmed1544
    @nazmaahmed1544 7 ปีที่แล้ว +1

    Really helpful. Thank you

  • @kayaksta
    @kayaksta 10 ปีที่แล้ว

    excellent Roger!

  • @AbdullahMQ
    @AbdullahMQ 8 ปีที่แล้ว +1

    Great video, but does any one tell me where is the following part about the mathematical part?

  • @PiyD2537
    @PiyD2537 10 ปีที่แล้ว

    Very Well Explained...!

  • @tomtong9859
    @tomtong9859 10 ปีที่แล้ว

    Brilliant video!

  • @niharikadharmapuri8343
    @niharikadharmapuri8343 6 ปีที่แล้ว +1

    well explained! thanks

  • @Med.School.Survival
    @Med.School.Survival 8 ปีที่แล้ว

    Great presentation :)

  • @rockernoobsthurein
    @rockernoobsthurein 10 ปีที่แล้ว

    Cool bro! Great job!

  • @AballVR6
    @AballVR6 10 ปีที่แล้ว +1

    I love your lectures!!! Could you do one on neuro?

  • @amirrezaeterafi3959
    @amirrezaeterafi3959 7 หลายเดือนก่อน

    Fantastic! thank you sir

  • @FaisalYami
    @FaisalYami 9 ปีที่แล้ว +1

    really good !!!

  • @miladchenaghlou5278
    @miladchenaghlou5278 8 ปีที่แล้ว +1

    Excellent !!!

  • @otacon3d
    @otacon3d 10 ปีที่แล้ว +28

    At the end of the video it says there's a "next video"
    Still waiting on a part 2, will it still come? Also can you explain positive and negative predictive values?

    • @FlyingFlaneur
      @FlyingFlaneur 3 ปีที่แล้ว +1

      They released another one. th-cam.com/video/ZPc6_UkdtzU/w-d-xo.html

  • @Princesscamiii
    @Princesscamiii 4 ปีที่แล้ว +1

    I love you! I will always refer to disease as "thief" and test to "alarm". hehe

  • @pammyholisticmed
    @pammyholisticmed 6 ปีที่แล้ว

    I appreciate the misspelling... I'm not alone! Evil e-i combos. THANK YOU for this video...

    • @Medcram
      @Medcram  6 ปีที่แล้ว

      +Pam deWilde Thanks for the comment, but what is the misspelling are you referring to?

    • @pammyholisticmed
      @pammyholisticmed 6 ปีที่แล้ว

      MedCram - Medical Lectures Explained CLEARLY : Forgive me, I meant to reply to the comment below. At minute 2:50ish, the word "Thief" is misspelled. The last person to comment made mention of it, or I wouldn't have noticed. This video was very helpful, truly.

    • @Medcram
      @Medcram  6 ปีที่แล้ว

      +Pam deWilde No problem at all, thanks for letting us know, and apologies for the misspelling!

  • @Gossypol
    @Gossypol 2 ปีที่แล้ว +1

    I have understood 50% of the video. But after 6:21 the next part was a bit confusing for me. Still for the 50% a thank you won’t be enough. But still thank you very much. 🤚

  • @naghmeazadi8294
    @naghmeazadi8294 7 ปีที่แล้ว

    Great as ussual.Thanks

  • @reneeshortz3404
    @reneeshortz3404 7 ปีที่แล้ว

    still a bit hard to grasp but I think I'm on the right track now!!

  • @ednamayseymour2053
    @ednamayseymour2053 5 ปีที่แล้ว +1

    THANK YOU!!!!

  • @vdp5837
    @vdp5837 7 ปีที่แล้ว +1

    Thanks!

  • @AK.ALMAHASNEH
    @AK.ALMAHASNEH ปีที่แล้ว

    thank u so much bro God bless you

  • @Eric-sq4hd
    @Eric-sq4hd 6 หลายเดือนก่อน

    we need this for npv. and ppv too

  • @Eric-sq4hd
    @Eric-sq4hd 6 หลายเดือนก่อน

    finally makes sense. wow..

  • @nnp418
    @nnp418 8 ปีที่แล้ว

    Hi, I am confused about the cutoff point for most of the true positives, the highest positive predictive value, the lowest negative predictive value and the highest specificity on graph. At what point, I get most of the true positives and at what point I get the highest specificity. I hope someone clarifies these. I would be much more appreciated.

  • @oodon3220
    @oodon3220 3 ปีที่แล้ว +1

    thank you!

  • @hlulanisambo1933
    @hlulanisambo1933 5 ปีที่แล้ว +1

    Thanks

  • @arnabsaha3006
    @arnabsaha3006 9 ปีที่แล้ว

    excellent...

  • @leezanewill-cordington8395
    @leezanewill-cordington8395 4 ปีที่แล้ว

    What is and why do tests have a "pre-setting"? 🤔. Take the covid-19 testing, could it be that the prerequisite for identifying the virus is highly similar to other viruses, thus giving false positives?

  • @zarsblackhorse123
    @zarsblackhorse123 2 ปีที่แล้ว

    Thank you.

  • @neard89
    @neard89 10 ปีที่แล้ว

    please upload next one...

  • @syedwraza6184
    @syedwraza6184 3 ปีที่แล้ว

    Great simple easy

  • @misanteojos5934
    @misanteojos5934 7 ปีที่แล้ว +2

    Thanks for the video its awesome, the car example is genius! but theif!!! makes my eyes hurt! hahaha

  • @helenhayes3298
    @helenhayes3298 2 ปีที่แล้ว

    What is the next video called please? I can't find it

  • @mechanizatorius
    @mechanizatorius 8 ปีที่แล้ว +2

    next video??

  • @Olu_Segun
    @Olu_Segun 4 ปีที่แล้ว

    Brilliant

  • @narjesseghatoleslam5307
    @narjesseghatoleslam5307 6 ปีที่แล้ว

    Dear Dr. Seheult,
    I did two different test for detection of a bacteria in the same population. Is it possible to calculate PPV, NPV, Sensitivity and Specificity of each test Separately with out gold standard ? Could you guide me please. Thank you for your consideration and confirmation would be appreciated.
    Sincerely,
    Narjes

    • @Medcram
      @Medcram  6 ปีที่แล้ว

      +Narjes Seghatoleslam in order to calculate Ppv and npv you need to have accurate info on disease. This requires a gold standard.

    • @narjesseghatoleslam5307
      @narjesseghatoleslam5307 6 ปีที่แล้ว

      Dear Dr. Seheult, thanks a lot for response, it is very nice of you.

  • @dr.ghaith
    @dr.ghaith 9 ปีที่แล้ว

    great thanx

  • @daradangana5625
    @daradangana5625 2 ปีที่แล้ว

    Thankssss

  • @boyuanchen4997
    @boyuanchen4997 4 ปีที่แล้ว

    Came here from Jeff Heaton's Machine Learning course :)

  • @Stonefalconetti
    @Stonefalconetti 9 ปีที่แล้ว +6

    Thief written "theif" and you are obviously a Native English speaker.. Yes, you really must be a very good doctor!!! ( No sarcasm. It's true. :))

  • @ioannisdikeoulias
    @ioannisdikeoulias 6 ปีที่แล้ว

    Specificity = TNR and Sensitivity = TPR...you mixed something up at your explanations 9:48 ...still good video!

  • @rayanhasnat2140
    @rayanhasnat2140 3 ปีที่แล้ว +1

    I think, sensitivity= TN/ TN+FN
    And specificity= TP/ TP+FP

  • @bhaskergowda2203
    @bhaskergowda2203 5 ปีที่แล้ว

    Could any one solve my problem or come a cross this problem pls let me know
    I have got trigenomial neuralgia from 17 yrs and I have been taking tegretol for all these years now lately l have developed sensitivitiness in leg and arm l cannot touch cold or hot water cannot walk longer pls help

  • @chiragmehta2955
    @chiragmehta2955 4 ปีที่แล้ว

    If population is on y axis,What is on x axis?

  • @Runcible2010
    @Runcible2010 6 ปีที่แล้ว

    Because of the epidemiological fallacy, test sensitivity should be high regardless of any demographic factors.

  • @dr.osmanelamin77
    @dr.osmanelamin77 10 ปีที่แล้ว

    Great :) Thanks alot

  • @johnweir1217
    @johnweir1217 3 ปีที่แล้ว

    Really good but I before e except after c. 😄

  • @yazanbaki5170
    @yazanbaki5170 2 ปีที่แล้ว

    Greeeeeeat

  • @joshuahornick3221
    @joshuahornick3221 5 ปีที่แล้ว +1

    "Thief", not "Theif." Still, very clear. Thank you.

  • @khankhan-cw2bq
    @khankhan-cw2bq 4 ปีที่แล้ว

    Dont understand car eg make it more difficult...

  • @monicaherrera-rickman3704
    @monicaherrera-rickman3704 7 ปีที่แล้ว

    👌🏻👌🏻🙌🏼🙌🏼👏👏

  • @beshrelaasar5
    @beshrelaasar5 6 ปีที่แล้ว

    High
    Sensitivity low specificty

  • @bhupensinha3767
    @bhupensinha3767 5 ปีที่แล้ว

    FP and FN aren't correctly put .. interchange em...

    • @Medcram
      @Medcram  5 ปีที่แล้ว +1

      +Bhupen Sinha false positives are people who don’t have disease but test positive. They go in the right column and top row by definition. False negatives are people who have disease but test negative. They go in the left column bottom row by definition.

  • @imeann...
    @imeann... 2 ปีที่แล้ว

    6:00

  • @themossman77
    @themossman77 4 ปีที่แล้ว +1

    Thief not theif....👌

  • @janicebaker3499
    @janicebaker3499 7 ปีที่แล้ว +30

    Spell thief correctly please

    • @joeymatee
      @joeymatee 7 ปีที่แล้ว +2

      lmaooo

    • @Medcram
      @Medcram  7 ปีที่แล้ว +17

      +janice baker yeah I know. "Thief" there!

    • @carog4969
      @carog4969 6 ปีที่แล้ว +1

      Get out of here

    • @ryezizzle
      @ryezizzle 6 ปีที่แล้ว +2

      unwatchable video! jkjk!

  • @swngstr
    @swngstr 5 ปีที่แล้ว

    What’s a boombox? Ha ha jk.

  • @awolf81
    @awolf81 3 ปีที่แล้ว

    “I don’t get it” *twirls long blonde hair with index finger*

  • @LD-pt5ur
    @LD-pt5ur 3 ปีที่แล้ว

    I like your tutorial. I hate the car alarm example.