I'm a Stage IV patient who is expected to survive for quite a while due to immunotherapy. New treatments have changed the game and my oncologist said that all the old terminology now has to be questioned.
Yeah I knew a guy who had gotten the "time to live" diagnosis, tumors in many places. Well immuniotherapy worked and he's now expecting to live a full life. I really hope I can get the same results as I've only just been diagnosed with cancer, they are still grading it.
immunotherapy is basically the best answer to cancer as its the OG way body prevents thousands of cancers each day the hard part is making immunotherapy work for each cancer
This is just like my course for being a medic for a kids organization, I'm really, really, really hoping I won't have to treat anything worse than a tummy ache and slight cuts. I'm quite mentally armored, but the things that could happen to those poor little guys...
My GF got Hopkins 1,5 years ago and was stage 4. Sounded very serious with the stage 4 part. But the doctor later explained this, Now we are cancer free for 6 months and hopefully all later check ups are good 💪
I use captions for clarity and sometimes, I think the typists have fun. @6:43 right after the comment about "underdeveloped" the words " just like me in highschool" popped up. I took a screenshot, but don't know where to send it. Stephan I always enjoy hearing you inform me about various subjects ❤.
I’m pretty sure some channels do the subtitles themselves… one camping channel I watch puts things in when she’s not talking like “cue crazy wind sounds” or “me wondering if I should give up” etc.
In this case I suspect it was a joke in the original script that ended up being cut, either because they didn't think a joke would be appropriate or because they needed to reduce the video run time.
The staging system changed while I was going through treatment for breast cancer in late 2018/early 2019. My oncologist didn't specify what stage I was at, but the surgeon said stage 3, since it had spread to the lymph nodes. When he double checked the notes, though, it was listed as a stage 2b. On a side note, men can get breast cancer as well. If you have a nipple that is inverted, or constantly itchy, get checked out. It's much easier to deal with as DCIS than as IDC.
Thank you for saying this! Not many people are aware of this, and for a lot of male breast cancer survivors, it's a somewhat taboo topic. Everyone, regardless of gender needs to be aware of the signs of breast cancer! I hope you are doing well these days!
My step father passed last year from male breast cancer. When the first tumor formed he never went to the dr it wasn't until the second tumor was visible in his armpit that he went. He was given a year to live but only managed 6½ months.
Exactly. All people have breast tissue. Its just that Testosterone prevents its maturation in ~50% of the population. But its still there, and it can get cancer.
I was diagnosed with stage 4 colon cancer, metastasized to my right side of the liver on my bday. Thanks to my medical team, and advancements in chemo, and my body responding extremely well, in the period of 8 months, I had a colon and liver resection. At the moment of this post, there is no indication of the cancer present in my body. My next goal is to smash the 5 year survival rate. Also, I during treatment, I had two haircuts.
Cancer research is mad Science experiments giving animals cancer and chemo times ten. That's worse than cancer itself. Mad Science experiments are worse than disease. Disease is a tragedy it's sad but it's not evil it's just nature on the other hand mad Science experiments torturing the weak and defenceless is evil. They should stop curing cancer, mad Science experiments are worse than cancer.
I hope you will maintain a healthy lifestyle by eating home cooked vegetables and meat, eating fruits and going to bed as early as possible. Don't eat fast food instead of your meals. Eat them separately. Those tips are not from professionals. So, you may choose what to eat.
My dad just told me they found cancer in his liver a couple hours ago. Almost the same time this was uploaded. And youtube just recommended me this video. Kinda scary.
@@SuviTuuliAllan what absolutely terrible energy to bring to a comment disclosing a cancer diagnosis. Somebody forgot to be awesome... That being said, @SavageNugz sending positive vibes your and your family's way, and i wish y'all the best through this journey! My family is currently rallying around my grandma who got a breast cancer diagnosis about 3 weeks ago. Be patient with yourself and let yourself feel any and all the feels and reach out for support when you need. 🧡🧡 Fork cancer.
@rylieread1865 is right. I was being a total arse. Sorry, @SavageNugz! You've done nothing to deserve such a cold reply. I wish you and your father good luck and the strength to endure the difficult time ahead. As someone whose spouse has cancer, I surely could be more considerate. We don't need to be mean to each other online. We need not perpetuate this cycle. Shame on me.
My mom had cancer, from your information I believe it was s2. Then it went into remission. 5 years later it came back as M4 (she was told that hitting 5y of remission was great, that likely it wouldn't come back. Not sure how it was explained to my mom but that's as I understood it from her. So getting S4 diagnosis blindsided her.) She was blessed with a few great years after that, but then her body started rejecting meds and her last 2 did her in. Thank you for spreading awareness and breaking things down so simply. It will, no doubt, help many people.
I made a video about this a couple years ago, but it's nice how this video goes into more detail about the numbers and letters. My oncologist doesn't like to get into a lot of the numbers with me, but I know I'm stage 4, grade 2 breast cancer, and awareness means everything to me, so thank you for helping people understand this kind of thing better. I'm told that my grade "won't typically change," and that I should take "remission" and "cure" out of my vocabulary. That said, I can keep words like "thriving" because I've also been told not to cancel any reservations or plans for my upcoming future. More people are living longer with stage 4 breast cancer than ever before, like upwards of 20+ years! We still need a cure, and "stage 4 needs more" attention, awareness, funding, and love now because we're getting close to breakthroughs. My current treatment (Truqap, a targeted therapy drug) was approved just last November (2023), and I've been managing my cancer very well since January 2020.
I am a stage 2a cancer patient with four surgeries behind me. I am thankful for this video though I understand what most of this means already, because I know it will help others going through what i've been going through this last year or two
I learned about diagnosis and staging when I worked at the American Cancer Society's 1-800 line for over 20 years. 3 years after the end of my time with ACS, I was diagnosed with stage IA breast cancer. Becoming the patient is its own learning experience and education. Meeting with all the professionals in my treatment team, I often nodded with familiarity as they reviewed information pertaining to my diagnosis and treatment. But it's a whole new experience when it's actually happening to you.
I'm a 2-year survivor of stage 2c ovarian cancer. I had surgery and then 6 cycles of carbo-taxol chemotherapy, 3 weeks apart. It's important to remember that we've come a long way in minimizing the side effects of chemo. However, it's still a pretty rough process. Remember to pamper yourself, eat healthy foods, and get outdoors for walks or other places when you feel up to it.
Has anybody ever read the closed captions? They add stuff! For example when talking about cells he says: "they end up looking immature and underdeveloped" But then the CC adds: 'like me in high school'
In this case I suspect it was a joke in the original script that ended up being cut, either because they didn't think a joke would be appropriate or because they needed to reduce the video run time.
Thank you for this. I am going tomorrow with a family member for a intake with an oncologist for a suspicious breast lump. This hopefully will help me support them through a possible diagnosis.
I watched the diabetes episode first and then came back to watch this from my watch later. This is such a smart series!! Thank you guys for making these.
My friend went from first detected (he was completely clear 8 weeks before on a regular ct scan for his heart) to dead in 3 months with pancreatic cancer . He was 55
Cancer research is mad Science experiments giving animals cancer and chemo times ten. That's worse than cancer. They should stop curing cancer. I feel bad for cancer patients but mad Science experiments are worse.
My dad was diagnosed with stage 3 colon cancer.Died 3 years later That was 13 years ago. My mum was diagnosed with stage 4 ovarian cancer. Died half a year later. This was 3 years ago. It was a horrific experience. I hope that modern medicine will advance soon to cure all cancer variants and left cancer only as a bad memory.
We also need medical misogyny to be dealt with and further care provided to earlier diagnose Ovarian cancers when women first present with symptoms. Sorry for your loss x
Can't say how much I appreciate this kind of thing. Takes the mystery away, makes the concepts a little less scary. I mean, it's still CANCER, it's going to be scary, but...well, as someone who never before understood what on earth was happening to folks with cancer, the more I learn the better. Especially since I'm apparently at risk for at least one kind myself x.x
Stage 1A estrogen and progesterone receptor breast cancer here! I got extremely lucky and my oncologist went through all the terms and their meanings. A bilateral mastectomy and hormone suppressants later and I am in remission.
I've watched cancer do it's work to family members, either some form of cancer or heart disease will get most of us, even if you do live to 100+ years, the body can only go so far.
My oncologists definitely didn't tell me most of that. I don't think the oncology folks even fully decided if I was stage 3C or 4, officially. It just kept saying "3C+" in their notes. They were all just so obsessed with trying to push drugs on me that no real useful information could be gleaned from them. (So I gave up on oncology and so I'm now just going to my regular doctor because she's very respectful of me and listens and cares, and I'm also talking to folks in palliative care to help me as my health declines, ideally with no drugs.)
I was diagnosed with stage II lung cancer around this time in 2015. I had a bilobectomy on my right lung, removing 2 of the 3 lobes. Not many of us survive 10 years but I'm working towards it. Was diagnosed with COPD too, so that was a bummer. Life eh?
Thank you for the video! I always appreciate how informative yet succinct Scishow is. I am wondering if you could maybe do a video exploring how cancer is diagnosed pathologically. I’m about to have my entire thyroid removed as a 26-year-old because they cannot determine for sure that my three thyroid nodules are not malignant. My biopsy was indeterminate and the genetic testing that is used to stratify those kinds of biopsy results came back moderate (45-60%) risk of malignancy. I’m a biochemist but I don’t know much yet about how each of those decisions were made. It’s very scary to be dealing with such a huge unknown as young as I am.
I was just told I have adenomas in my stomach due to long term medication side effects. Benign, but still considered precancerous. Very scary since I'm under 30.
I have an extremely rare cancer called LPL IgA. Very similar to waldenstroems but different. Could you do a show on blood cancers like mine? There would be some very happy people who would appreciate it if you could.
My dad’s cancer has distant spread but is well-differentiated. Odds are that cancer was brewing for years and years to spread to his liver because the cancer cells are still well-differentiated. So he’s stage four but grade 1. Wild.
I’ve lost family to cancer before, and I even have a family member who’s currently dealing with a deadly form of brain tumor. I hope cancer knowledge and treatment advance enough to one day stop people from suffering, dying, and losing loved ones from this awful disease. 🫡
In this case I suspect it was a joke in the original script that ended up being cut, either because they didn't think a joke would be appropriate or because they needed to reduce the video run time.
Immunohistochemistry or molecular markers often matter a lot, depending on the type of cancer. Like in breast cancer ER/PR/Her2 receptor status plays a big role in prognosis and treatment options. Or in central nervous system tumors where it actually defines the grade (eg, a WHO grade II/III astrocytoma by histopathology actually becomes grade IV (previously basically reserved for glioblastoma) and is treated like a glioblastoma if it is IDH wild type). Hard not to see a future where molecular specific diagnosis and treatment will have increasing role in other cancers too.
Correction, it is pathologist that check the tissue biopsy. They are very underappreciated but really important in cancer diagnosis. Been working with them for my cancer research and they can be kinda forgotten somehow in medical community
My dad has had 4 different cancers. Stage III Testicular cancer in 2000 Brasil cell skin cancer on face and back Stage IV Thyroid cancer And currently Battling and beating Stage III Spindle cell soft tissue sarcoma
@jessicaras4540 imaginary friends are not real. Do not come in here and talk about your imaginary friend while my dad is dealing with cancer. That is offensive do not do that.
One thing I have not heard is the fact that some tumors are not cancerous. I mention this only because it's important to remember that the words "tumor" and "cancer" are not synonymous. Because not all tumors are cancerous. Unfortunately, in this day and age, some doctors do not make a distinction between the two. I had two tumors, neither of which were cancerous. The first was biopsied after being removed. It was removed mostly because it was blocking my large intestine and making it impossible for my body to digest food. It was not even attached to my intestines. When it was biopsied, it was found to be non-cancerous. The second, however, has not been removed because #1) It is very small (.05mm) and, after two biopsies, has not shown any cancer. Yet my doctors keep "urging" me to have it removed... and I keep asking why. The answers: Because 'it could' metastasize. Yet, with the smallest dose of a low-level chemo therapy -- which, I am told, I will have to take for the rest of my life anyway -- it keeps shrinking. It was originally 2.3 cm. The argument came up because I also have an immunity condition that makes any surgery very risky; much riskier than for most people. So, weighing the risks from that perspective, I come out saying, "no surgery." This has gone on for almost 3 years now. And, yes, even though I have been through one surgery and survived is no guarantee that I will survive a second. In fact, because I am older, that is less likely. But one thing that has really annoyed me was that, when I asked "is the tumor cancerous?" The response was always some variation of "well, it's a tumor." Of course, this did not answer my question. Worse, it implied that the two are synonymous. But they are not. There is such a thing as a benign tumor. It took me almost two years of research and reading about cancer markers and asking the right questions to find out that, no, it was not cancerous. Also? Clearly, I have given cancer and tumors a lot of thought over the last 5 years (this includes the first tumor prior to removal.) Calling it a disease is a misnomer. Cancer and tumors are a reaction the body has to a certain situation or a certain set of circumstances. It's like having a fever, rather than a virus. The fever is the response to a virus but it is the body trying to manage a specific problem. And, BTW? Oftentimes the activating circumstance is radiation exposure. I mention this because it is infuriating that women are still compelled to get mammograms which shoot an enormous amount of radiation directly at each breast. I wonder... how many women develop breast cancer that is detected only after their 2nd mammogram? Also, no doctor ever mentions it, but a woman CAN get a sonogram instead. These are every bit as effective at detecting lumps in the breast and use only sound waves; no radiation. Why are mammograms even allowed anymore, when it was determined in the early 2000's that there is a direct correlation between mammograms and later development of breast cancer? That's what I want to know.
It's worth mentioning that the TNM staging is usually used for the stage staging. So most T?N?M1 stages are a stage 4 cancer. And staging criteria vary slightly from country to country depending on the system used, in america its based on the specifications of the AJCC (American Joint Commitee on Cancer) and in the UK they use the specifications by UICC ( Union for international cancer control) As well as if it's classed as a more generic location cancer vs a more specified location (For example, classifying something as a skin cancer vs as a skin of the lip cancer. Just small detail differences) There are also more specific "staging" systems used alongside TNM & Stage for specific organs, as mentioned in the video, like FIGO (International Federation of Gynaecology and Obstetrics) or NPI (Nottingham Prognostics Index). Then it is worth also knowing that you can have Clinical staging and Pathological staging. Clinical staging will be based on observations, imaging tests, biopsies etc. pathological staging can take into account the clincal stage, as well as further information from histopathology or haemopathology testing to get a more accurate reflection of the stage of the cancer. If you want to find out more about the staging systems, I would say going to the source is highly beneficial, as they do produce detailed datasets for the various cancer diagnosis. This is AJCC www.facs.org/quality-programs/cancer-programs/american-joint-committee-on-cancer/version-9-protocols-and-ajcc-staging-online-unveiled/ Unfortunatley it's not as easy to come across free copies of the latest version of AJCC (Version 9) This is UICC's latest edition mom.gov.az/resources/content_files/ebook/TNM-Classification-of-Malignant-Tumours-8th-edition.pdf and also in the UK we have RCPath (Royal College of Pathologists) www.rcpath.org/profession/guidelines/cancer-datasets-and-tissue-pathways.html The above are the authorities for the specifications of cancer classification. I've seen them in use in multiple countries.
My mother had cancer in the breast around 10 years ago. She had a massive tumor but it never spread anywhere else in the body. She’s still cancer free today. I suppose her T value would have been 4, but the others were 0. They considered cutting off the breast but the tumor was big and a little too high on the breast for it to be safe. So she went through chemotherapy and is living fine. She has to go get checked out every year though.
I know this is a rather serious topic with it being about cancer and such, but I have to give credit to the person that did the captions for this episode and made a funny bit at 6:42 - 6:43 and I just gotta say: Same my dude. Same. But on the topic of the video topic, this makes me wonder what the letter string was for my uncle. He passed away a year ago as of the 23rd and I know it's been rough on the family. Especially on my grandparents. They always seemed rather healthy and took care of themselves. But since then.... it's like they've aged a decade. Especially my grandmother. For being in her 80's, she didn't look it at all. Now you can see it's gotten to her and starting to visibly show her age. It's even worse because my uncle just got married again a year or two prior to his passing. Plus the doctors gave the all clear. That he was in remission and was doing really really good and getting better! So when we were told that it came back and got really aggressive.... Well.... Let's just say that he was gone in about a month and passed in his sleep with his wife next to him in their home.
@jessicaras4540 That's a moment in history that I don't see happening today. Also, the man who predicted the bosun which was finally found and named after him, died a few days ago. Hank mentioned a few people, and I suggested that Mr Higgs could also have been mentioned. My comment did not refer to any faith, religion or commonly-held belief. But thank you for the reminder of Jesus' progressive attitude toward ill people. Jesus did not profit from healing them. I think that is an excellent way to approach healing of any kind.
Overall good video, but some inaccuracies. For example, lung cancer that has spread to hilar nodes only (N1 nodes) is usually a stage-II cancer. Lymph node spread isn't just stage-III. Plus, the true meaning of a tumor being in-situ is that the tumor hasn't yet become invasive. A tumor must become invasive to be able to metastasize.
I had stage 0 breast cancer in situ, and we got it out in great timing because after they tested it, it was a grade 3. Whew! Insane lucky. But terrifying.
the second way might've been more useful for my mom's cancer. the original colon cancer tumor was tiny and not doing much, but it had somehow metastasized to her brain where it was causing problems. so saying she had brain cancer was just incorrect, but saying stage iv colon cancer implies a big problem in or at least near the colon, which was also not the case lol
I have multiple myeloma. I went through all manner of tests and still do. I underwent a stem cell transplant which is sort of a hard reset of your bone marrow. Trust me, you NEVER want to go through it. It sucks. But the cancer had to be beaten into remission first, which was no fun either. Early diagnosis is key, but that doesn't mean you can't beat the disease if you don't get an early diagnosis. It jist means the treatment will be different. Multiple myeloma is not curable. It will rear its ugly head again someday. But new treatments are being found all the time.
Dad had stage 0 pancreatic cancer.He had whiple surgery and died a week later after falling at home. I have 4 first degree relatives who had cancer so I started screening in my mid-20s.
Question: why do women have permanent breasts when other mammals only develop them during pregnancy? And why is it called yellow fever if not everyone gets jaundice with it?
Stage 1 +++ bc idc two month NED but it had spread to lymph. I wish I had seen this when I was first diagnosed two years ago. Go over in detail. 😂 what a joke. I got six minutes with the oncologist. Barely enough time. To tell me when treatment would start.
Ich habe noch kein Koffeinhaltiges Produkt probiert, das genug Koffein enthielt, so dass es auch nur ein geringe Wirkung auf mich hatte. Vielleicht bin ich immun
@jessicaras4540 Hi Jessica. I prayed to Jesus last night and He said proselytizing in the TH-cam comment section makes Him sad. There are better ways to spread His message. Also, Hell isn't real.
I appreciate your attempt to explain such a complicated topic in under 10 minutes, but next time please consult with a pathologist before releasing such a video. There are a bunch of small inaccuracies. First and foremost, any cancer diagnosis requires a biopsy or resection and a microscopic assessment by a pathologist. Pathology is the cornerstone of cancer diagnosis. This goes far beyond establishing grade, but is also key in establishing the TNM stage. CT scans are often helpful in determining stage, but they require correlation with microscopy. No patient will get chemo for a solid tumor without a confirmation of malignancy by a pathologist. Oh and electronic microscopy (of which you showed an image) is NOT used in the assessment or any cancer.
Whoo he didn't even touch on the genetic tests for your tumor! your cancer behaves differently based on what part of the DNA is misbehaving, and we can test for "breakable" genes (genetic susceptibility) or even if the DNA has been "broken" in your cells - so your tumor often has slightly different DNA than you, by definition!
If you're going to sarcastically whinge about an AI generated image, the least you could do is verify it's actually an AI generated image. Took me a whole 30 seconds to find out it's a Getty stock image made by koto_feja who has a whole portfolio of 3d modeling with Blender.
It would be nice if a channel that promotes science would ask serious questions about the so-called vaccine and long vaccine and long covid. Develope a little bit of courage. If you really care about science you can’t possibly be ok with the lies we’ve been told.
Not being a crazy merry can I'd be interested to know about these lies 'they' are telling us. Sigh. From my viewpoint from across the pond I honestly think the biggest problem is education, or lack of it. Same things are happening in England (I won't include Scotland, Wales or Northern Ireland) as the USA. Onanists sucked into pseudo science and conspiracy theories. This type of batshit crazy stuff will send America back to the dark ages. I also find it mindblowing that there's a chance the American electorate will vote for The Orange One in November.
I'm a Stage IV patient who is expected to survive for quite a while due to immunotherapy. New treatments have changed the game and my oncologist said that all the old terminology now has to be questioned.
Yeah I knew a guy who had gotten the "time to live" diagnosis, tumors in many places. Well immuniotherapy worked and he's now expecting to live a full life. I really hope I can get the same results as I've only just been diagnosed with cancer, they are still grading it.
good luck man, best wishes!
i pray that you beat cancer and continue to live a long life
immunotherapy is basically the best answer to cancer as its the OG way body prevents thousands of cancers each day the hard part is making immunotherapy work for each cancer
@@Iflie best of luck to you
As I am learning about this ... I am also really hoping I never have to need this information.
I hope none of us needs this.
Sadly some of us already do 🙁
Prevention! Eat healthy
girl.
@@Stilllife1999yep, just got diagnosed last week. This video is perfect timing for me, actually
This is just like my course for being a medic for a kids organization, I'm really, really, really hoping I won't have to treat anything worse than a tummy ache and slight cuts. I'm quite mentally armored, but the things that could happen to those poor little guys...
My GF got Hopkins 1,5 years ago and was stage 4. Sounded very serious with the stage 4 part. But the doctor later explained this, Now we are cancer free for 6 months and hopefully all later check ups are good 💪
I use captions for clarity and sometimes, I think the typists have fun. @6:43 right after the comment about "underdeveloped" the words " just like me in highschool" popped up. I took a screenshot, but don't know where to send it.
Stephan I always enjoy hearing you inform me about various subjects ❤.
It's even worse now with the computer trying to hear it and transcribe them! 😂😂😂
That was awesome. Made my day 😂
I’m pretty sure some channels do the subtitles themselves… one camping channel I watch puts things in when she’s not talking like “cue crazy wind sounds” or “me wondering if I should give up” etc.
@@lolcatz88 yeah! I love it when they do that! All the extra context…
In this case I suspect it was a joke in the original script that ended up being cut, either because they didn't think a joke would be appropriate or because they needed to reduce the video run time.
The staging system changed while I was going through treatment for breast cancer in late 2018/early 2019. My oncologist didn't specify what stage I was at, but the surgeon said stage 3, since it had spread to the lymph nodes. When he double checked the notes, though, it was listed as a stage 2b.
On a side note, men can get breast cancer as well. If you have a nipple that is inverted, or constantly itchy, get checked out. It's much easier to deal with as DCIS than as IDC.
Thank you for saying this! Not many people are aware of this, and for a lot of male breast cancer survivors, it's a somewhat taboo topic. Everyone, regardless of gender needs to be aware of the signs of breast cancer!
I hope you are doing well these days!
My step father passed last year from male breast cancer. When the first tumor formed he never went to the dr it wasn't until the second tumor was visible in his armpit that he went. He was given a year to live but only managed 6½ months.
Exactly. All people have breast tissue. Its just that Testosterone prevents its maturation in ~50% of the population. But its still there, and it can get cancer.
@jessicaras4540 That's great, but Jesus isn't here right now. Do not turn people away from seeking proper treatment.
I was diagnosed with stage 4 colon cancer, metastasized to my right side of the liver on my bday. Thanks to my medical team, and advancements in chemo, and my body responding extremely well, in the period of 8 months, I had a colon and liver resection. At the moment of this post, there is no indication of the cancer present in my body. My next goal is to smash the 5 year survival rate.
Also, I during treatment, I had two haircuts.
!HAIRCUTS
Cancer research is mad Science experiments giving animals cancer and chemo times ten. That's worse than cancer itself. Mad Science experiments are worse than disease. Disease is a tragedy it's sad but it's not evil it's just nature on the other hand mad Science experiments torturing the weak and defenceless is evil. They should stop curing cancer, mad Science experiments are worse than cancer.
I hope you will maintain a healthy lifestyle by eating home cooked vegetables and meat, eating fruits and going to bed as early as possible. Don't eat fast food instead of your meals. Eat them separately.
Those tips are not from professionals. So, you may choose what to eat.
Well explained. I had to figure these out the hard way when my wife got diagnosed 9 years ago. She’s been gone 11 months to the day.
Felt really sad reading this. Hope you're fine brother. I wish nobody has to go through this.
@@beasty007 I will be. And no one should, but so many of us will.
My dad just told me they found cancer in his liver a couple hours ago. Almost the same time this was uploaded. And youtube just recommended me this video. Kinda scary.
The fifth character in your comment is an A. My keyboard has an A. Kinda scary.
Good luck to your dad and your family.
@@SuviTuuliAllan what absolutely terrible energy to bring to a comment disclosing a cancer diagnosis. Somebody forgot to be awesome...
That being said, @SavageNugz sending positive vibes your and your family's way, and i wish y'all the best through this journey! My family is currently rallying around my grandma who got a breast cancer diagnosis about 3 weeks ago. Be patient with yourself and let yourself feel any and all the feels and reach out for support when you need. 🧡🧡 Fork cancer.
@@alyssasabrae7943best of luck to the both of you. My dad is beating his 4th cancer right now.
@rylieread1865 is right. I was being a total arse. Sorry, @SavageNugz! You've done nothing to deserve such a cold reply. I wish you and your father good luck and the strength to endure the difficult time ahead.
As someone whose spouse has cancer, I surely could be more considerate. We don't need to be mean to each other online. We need not perpetuate this cycle. Shame on me.
My mom had cancer, from your information I believe it was s2. Then it went into remission. 5 years later it came back as M4 (she was told that hitting 5y of remission was great, that likely it wouldn't come back. Not sure how it was explained to my mom but that's as I understood it from her. So getting S4 diagnosis blindsided her.) She was blessed with a few great years after that, but then her body started rejecting meds and her last 2 did her in.
Thank you for spreading awareness and breaking things down so simply. It will, no doubt, help many people.
I made a video about this a couple years ago, but it's nice how this video goes into more detail about the numbers and letters. My oncologist doesn't like to get into a lot of the numbers with me, but I know I'm stage 4, grade 2 breast cancer, and awareness means everything to me, so thank you for helping people understand this kind of thing better. I'm told that my grade "won't typically change," and that I should take "remission" and "cure" out of my vocabulary.
That said, I can keep words like "thriving" because I've also been told not to cancel any reservations or plans for my upcoming future.
More people are living longer with stage 4 breast cancer than ever before, like upwards of 20+ years! We still need a cure, and "stage 4 needs more" attention, awareness, funding, and love now because we're getting close to breakthroughs. My current treatment (Truqap, a targeted therapy drug) was approved just last November (2023), and I've been managing my cancer very well since January 2020.
I am a stage 2a cancer patient with four surgeries behind me. I am thankful for this video though I understand what most of this means already, because I know it will help others going through what i've been going through this last year or two
I learned about diagnosis and staging when I worked at the American Cancer Society's 1-800 line for over 20 years. 3 years after the end of my time with ACS, I was diagnosed with stage IA breast cancer. Becoming the patient is its own learning experience and education. Meeting with all the professionals in my treatment team, I often nodded with familiarity as they reviewed information pertaining to my diagnosis and treatment. But it's a whole new experience when it's actually happening to you.
I'm a 2-year survivor of stage 2c ovarian cancer. I had surgery and then 6 cycles of carbo-taxol chemotherapy, 3 weeks apart.
It's important to remember that we've come a long way in minimizing the side effects of chemo. However, it's still a pretty rough process. Remember to pamper yourself, eat healthy foods, and get outdoors for walks or other places when you feel up to it.
Well done guys. We are getting better at dealing with cancer.
Based on the title I thought this would be hosted by Hank talking about his diagnosis 😅
I thought so too.
Hank is thankfully in complete remission
@@WinterWitch01 Yes, Thank God!
I thought "wait, ANOTHER young healthy sci show host has cancer?"
💀👀
i am really loving the new backgrounds. they have such a good energy to them.
Has anybody ever read the closed captions? They add stuff! For example when talking about cells he says: "they end up looking immature and underdeveloped" But then the CC adds: 'like me in high school'
In this case I suspect it was a joke in the original script that ended up being cut, either because they didn't think a joke would be appropriate or because they needed to reduce the video run time.
Thank you for this. I am going tomorrow with a family member for a intake with an oncologist for a suspicious breast lump. This hopefully will help me support them through a possible diagnosis.
I watched the diabetes episode first and then came back to watch this from my watch later. This is such a smart series!! Thank you guys for making these.
My friend went from first detected (he was completely clear 8 weeks before on a regular ct scan for his heart) to dead in 3 months with pancreatic cancer . He was 55
Cancer research is mad Science experiments giving animals cancer and chemo times ten. That's worse than cancer. They should stop curing cancer. I feel bad for cancer patients but mad Science experiments are worse.
My dad was diagnosed with stage 3 colon cancer.Died 3 years later That was 13 years ago.
My mum was diagnosed with stage 4 ovarian cancer. Died half a year later. This was 3 years ago.
It was a horrific experience. I hope that modern medicine will advance soon to cure all cancer variants and left cancer only as a bad memory.
We also need medical misogyny to be dealt with and further care provided to earlier diagnose Ovarian cancers when women first present with symptoms. Sorry for your loss x
Can't say how much I appreciate this kind of thing. Takes the mystery away, makes the concepts a little less scary. I mean, it's still CANCER, it's going to be scary, but...well, as someone who never before understood what on earth was happening to folks with cancer, the more I learn the better.
Especially since I'm apparently at risk for at least one kind myself x.x
Stage 1A estrogen and progesterone receptor breast cancer here! I got extremely lucky and my oncologist went through all the terms and their meanings. A bilateral mastectomy and hormone suppressants later and I am in remission.
I've watched cancer do it's work to family members, either some form of cancer or heart disease will get most of us, even if you do live to 100+ years, the body can only go so far.
I recently lost my wife to cancer. Best wishes to you on your journey
My oncologists definitely didn't tell me most of that. I don't think the oncology folks even fully decided if I was stage 3C or 4, officially. It just kept saying "3C+" in their notes. They were all just so obsessed with trying to push drugs on me that no real useful information could be gleaned from them. (So I gave up on oncology and so I'm now just going to my regular doctor because she's very respectful of me and listens and cares, and I'm also talking to folks in palliative care to help me as my health declines, ideally with no drugs.)
I work in vetmed Oncology. We use many of the same terms, but also different ones
is it true that you use fenbendazole and ivermectin to treat cancers in animals?
I was diagnosed with stage II lung cancer around this time in 2015. I had a bilobectomy on my right lung, removing 2 of the 3 lobes. Not many of us survive 10 years but I'm working towards it. Was diagnosed with COPD too, so that was a bummer. Life eh?
Thank you for the video! I always appreciate how informative yet succinct Scishow is. I am wondering if you could maybe do a video exploring how cancer is diagnosed pathologically. I’m about to have my entire thyroid removed as a 26-year-old because they cannot determine for sure that my three thyroid nodules are not malignant. My biopsy was indeterminate and the genetic testing that is used to stratify those kinds of biopsy results came back moderate (45-60%) risk of malignancy. I’m a biochemist but I don’t know much yet about how each of those decisions were made. It’s very scary to be dealing with such a huge unknown as young as I am.
I was just told I have adenomas in my stomach due to long term medication side effects. Benign, but still considered precancerous. Very scary since I'm under 30.
I never thought the knowledge would be needed this early.... 😢
I have an extremely rare cancer called LPL IgA.
Very similar to waldenstroems but different. Could you do a show on blood cancers like mine?
There would be some very happy people who would appreciate it if you could.
My dad’s cancer has distant spread but is well-differentiated. Odds are that cancer was brewing for years and years to spread to his liver because the cancer cells are still well-differentiated. So he’s stage four but grade 1. Wild.
My father died because of cancer, I hate this disease with all my forces.
Same here, just lost my dad last August to HPV related throat cancer. A month and a day before his 60th birthday
I’ve lost family to cancer before, and I even have a family member who’s currently dealing with a deadly form of brain tumor. I hope cancer knowledge and treatment advance enough to one day stop people from suffering, dying, and losing loved ones from this awful disease. 🫡
Cancer is not "this disease", it's like 200 diseases
not slick with the subtitles @ 6:40 😭
HELP i didn't even notice 😂
In this case I suspect it was a joke in the original script that ended up being cut, either because they didn't think a joke would be appropriate or because they needed to reduce the video run time.
@jessicaras4540 girl what?
This is really informative, thanks!
Thanks!
Immunohistochemistry or molecular markers often matter a lot, depending on the type of cancer. Like in breast cancer ER/PR/Her2 receptor status plays a big role in prognosis and treatment options. Or in central nervous system tumors where it actually defines the grade (eg, a WHO grade II/III astrocytoma by histopathology actually becomes grade IV (previously basically reserved for glioblastoma) and is treated like a glioblastoma if it is IDH wild type). Hard not to see a future where molecular specific diagnosis and treatment will have increasing role in other cancers too.
Correction, it is pathologist that check the tissue biopsy. They are very underappreciated but really important in cancer diagnosis. Been working with them for my cancer research and they can be kinda forgotten somehow in medical community
My dad has had 4 different cancers.
Stage III Testicular cancer in 2000
Brasil cell skin cancer on face and back
Stage IV Thyroid cancer
And currently Battling and beating Stage III Spindle cell soft tissue sarcoma
@jessicaras4540 imaginary friends are not real. Do not come in here and talk about your imaginary friend while my dad is dealing with cancer. That is offensive do not do that.
Dealing with hepatocellular carcinoma in the liver.
Listen to your doctors and kick its butt, brother/sister!
@jessicaras4540 What are Jesus's office hours?
One thing I have not heard is the fact that some tumors are not cancerous. I mention this only because it's important to remember that the words "tumor" and "cancer" are not synonymous. Because not all tumors are cancerous. Unfortunately, in this day and age, some doctors do not make a distinction between the two.
I had two tumors, neither of which were cancerous. The first was biopsied after being removed. It was removed mostly because it was blocking my large intestine and making it impossible for my body to digest food. It was not even attached to my intestines. When it was biopsied, it was found to be non-cancerous.
The second, however, has not been removed because #1) It is very small (.05mm) and, after two biopsies, has not shown any cancer. Yet my doctors keep "urging" me to have it removed... and I keep asking why. The answers: Because 'it could' metastasize. Yet, with the smallest dose of a low-level chemo therapy -- which, I am told, I will have to take for the rest of my life anyway -- it keeps shrinking. It was originally 2.3 cm.
The argument came up because I also have an immunity condition that makes any surgery very risky; much riskier than for most people. So, weighing the risks from that perspective, I come out saying, "no surgery." This has gone on for almost 3 years now. And, yes, even though I have been through one surgery and survived is no guarantee that I will survive a second. In fact, because I am older, that is less likely.
But one thing that has really annoyed me was that, when I asked "is the tumor cancerous?" The response was always some variation of "well, it's a tumor." Of course, this did not answer my question. Worse, it implied that the two are synonymous. But they are not. There is such a thing as a benign tumor. It took me almost two years of research and reading about cancer markers and asking the right questions to find out that, no, it was not cancerous.
Also? Clearly, I have given cancer and tumors a lot of thought over the last 5 years (this includes the first tumor prior to removal.) Calling it a disease is a misnomer. Cancer and tumors are a reaction the body has to a certain situation or a certain set of circumstances. It's like having a fever, rather than a virus. The fever is the response to a virus but it is the body trying to manage a specific problem.
And, BTW? Oftentimes the activating circumstance is radiation exposure. I mention this because it is infuriating that women are still compelled to get mammograms which shoot an enormous amount of radiation directly at each breast. I wonder... how many women develop breast cancer that is detected only after their 2nd mammogram? Also, no doctor ever mentions it, but a woman CAN get a sonogram instead. These are every bit as effective at detecting lumps in the breast and use only sound waves; no radiation. Why are mammograms even allowed anymore, when it was determined in the early 2000's that there is a direct correlation between mammograms and later development of breast cancer? That's what I want to know.
Thank you
It's worth mentioning that the TNM staging is usually used for the stage staging. So most T?N?M1 stages are a stage 4 cancer. And staging criteria vary slightly from country to country depending on the system used, in america its based on the specifications of the AJCC (American Joint Commitee on Cancer) and in the UK they use the specifications by UICC ( Union for international cancer control) As well as if it's classed as a more generic location cancer vs a more specified location (For example, classifying something as a skin cancer vs as a skin of the lip cancer. Just small detail differences)
There are also more specific "staging" systems used alongside TNM & Stage for specific organs, as mentioned in the video, like FIGO (International Federation of Gynaecology and Obstetrics) or NPI (Nottingham Prognostics Index).
Then it is worth also knowing that you can have Clinical staging and Pathological staging. Clinical staging will be based on observations, imaging tests, biopsies etc. pathological staging can take into account the clincal stage, as well as further information from histopathology or haemopathology testing to get a more accurate reflection of the stage of the cancer.
If you want to find out more about the staging systems, I would say going to the source is highly beneficial, as they do produce detailed datasets for the various cancer diagnosis.
This is AJCC
www.facs.org/quality-programs/cancer-programs/american-joint-committee-on-cancer/version-9-protocols-and-ajcc-staging-online-unveiled/
Unfortunatley it's not as easy to come across free copies of the latest version of AJCC (Version 9)
This is UICC's latest edition
mom.gov.az/resources/content_files/ebook/TNM-Classification-of-Malignant-Tumours-8th-edition.pdf
and also in the UK we have RCPath (Royal College of Pathologists)
www.rcpath.org/profession/guidelines/cancer-datasets-and-tissue-pathways.html
The above are the authorities for the specifications of cancer classification. I've seen them in use in multiple countries.
My mother had cancer in the breast around 10 years ago. She had a massive tumor but it never spread anywhere else in the body. She’s still cancer free today. I suppose her T value would have been 4, but the others were 0. They considered cutting off the breast but the tumor was big and a little too high on the breast for it to be safe. So she went through chemotherapy and is living fine. She has to go get checked out every year though.
I know this is a rather serious topic with it being about cancer and such, but I have to give credit to the person that did the captions for this episode and made a funny bit at 6:42 - 6:43 and I just gotta say: Same my dude. Same.
But on the topic of the video topic, this makes me wonder what the letter string was for my uncle. He passed away a year ago as of the 23rd and I know it's been rough on the family. Especially on my grandparents. They always seemed rather healthy and took care of themselves. But since then.... it's like they've aged a decade. Especially my grandmother. For being in her 80's, she didn't look it at all. Now you can see it's gotten to her and starting to visibly show her age. It's even worse because my uncle just got married again a year or two prior to his passing. Plus the doctors gave the all clear. That he was in remission and was doing really really good and getting better! So when we were told that it came back and got really aggressive.... Well.... Let's just say that he was gone in about a month and passed in his sleep with his wife next to him in their home.
I thought that another person on scishow got cancer. This title scared me.
You might post a video about Mr Higgs, who died in the last day or so.
@jessicaras4540 That's a moment in history that I don't see happening today. Also, the man who predicted the bosun which was finally found and named after him, died a few days ago. Hank mentioned a few people, and I suggested that Mr Higgs could also have been mentioned. My comment did not refer to any faith, religion or commonly-held belief. But thank you for the reminder of Jesus' progressive attitude toward ill people. Jesus did not profit from healing them. I think that is an excellent way to approach healing of any kind.
Overall good video, but some inaccuracies. For example, lung cancer that has spread to hilar nodes only (N1 nodes) is usually a stage-II cancer. Lymph node spread isn't just stage-III. Plus, the true meaning of a tumor being in-situ is that the tumor hasn't yet become invasive. A tumor must become invasive to be able to metastasize.
Do you guys have all the cancer videos in one playlist? I skimmed but didn't see one.
Did stagings change? Lymph node involvement typically started with stage 2.
Thank you.
I'm not in high school yet... For more info go to 6:35 with subtitles on! 😂
I had stage 0 breast cancer in situ, and we got it out in great timing because after they tested it, it was a grade 3. Whew! Insane lucky. But terrifying.
I'm in school and we just had a lecture about grading and staging cancer. Get out of my head! Lol
You can have BC in lymph nodes and have stage 2. Depends how many nodes etc.
Man I need something to organize my pictures….. 😅add that to your notion!
Please do a video about terminal cancer and how psilocybin mushroom can help treat end of life depression caused by cancer.
Cancer means I need to cook meth.
There will be consequences…
Make sure it's not purple they are onto it
the second way might've been more useful for my mom's cancer. the original colon cancer tumor was tiny and not doing much, but it had somehow metastasized to her brain where it was causing problems. so saying she had brain cancer was just incorrect, but saying stage iv colon cancer implies a big problem in or at least near the colon, which was also not the case lol
Is it there a difference between undifferentiated cells anda stem cells?
I would have thought Hank would be the best person to give out this info.
I bet he was dying to get a break from cancer.
I have multiple myeloma. I went through all manner of tests and still do. I underwent a stem cell transplant which is sort of a hard reset of your bone marrow. Trust me, you NEVER want to go through it. It sucks. But the cancer had to be beaten into remission first, which was no fun either. Early diagnosis is key, but that doesn't mean you can't beat the disease if you don't get an early diagnosis. It jist means the treatment will be different. Multiple myeloma is not curable. It will rear its ugly head again someday. But new treatments are being found all the time.
Dad had stage 0 pancreatic cancer.He had whiple surgery and died a week later after falling at home.
I have 4 first degree relatives who had cancer so I started screening in my mid-20s.
I’m so sorry 💐
6:42 LOLLLLLLLLLLLLLLLLLLLLLLLLL the subtitle
Interesting. I would have assumed more 'differentiated' meant more dissimilar to the original healthy cells.
Differentiated from each other. Each cell should have clear edges, and stand by itself on the slides.
Question: why do women have permanent breasts when other mammals only develop them during pregnancy? And why is it called yellow fever if not everyone gets jaundice with it?
6:42 Easter egg in subtitles😃
N=2, l=1, ml=0, ms=-1/2
Noooooooooooooooooooo, oh whyyyyy
Heh, shouldn't Hank have hosted this one? 😹
How the hell did they find someone who sounds so similar to Hank?
@jessicaras4540 I am afraid I have no idea why you have quoted those verses to me.
Hoping Hanks is okay
Hank is in complete remission
He's cancer free.
Stage 1 +++ bc idc two month NED but it had spread to lymph. I wish I had seen this when I was first diagnosed two years ago.
Go over in detail. 😂 what a joke. I got six minutes with the oncologist. Barely enough time. To tell me when treatment would start.
A comment for the algorithm
mom had stage 0 breast cancer twice
Ich habe noch kein Koffeinhaltiges Produkt probiert, das genug Koffein enthielt, so dass es auch nur ein geringe Wirkung auf mich hatte.
Vielleicht bin ich immun
Some may benefit from Novocure's technology.
Hi Stefan!
This is a sad video.
@jessicaras4540 Hi Jessica. I prayed to Jesus last night and He said proselytizing in the TH-cam comment section makes Him sad. There are better ways to spread His message. Also, Hell isn't real.
Suprised this isnt presented by Hank.
hiiiiii
and there are also things that are worse than cancer like the ongoing culture wars
@jessicaras4540 God is so good! - TamtamPamela
Bro, i help you to dubbed your videos in hindi language for Indian
Hindi videos will provide you a lots of new members and viewers
Anyone get Nickelodeon vibes with the new background? Sorry guys just my kneejerk reaction I guess lol
I appreciate your attempt to explain such a complicated topic in under 10 minutes, but next time please consult with a pathologist before releasing such a video. There are a bunch of small inaccuracies. First and foremost, any cancer diagnosis requires a biopsy or resection and a microscopic assessment by a pathologist. Pathology is the cornerstone of cancer diagnosis. This goes far beyond establishing grade, but is also key in establishing the TNM stage. CT scans are often helpful in determining stage, but they require correlation with microscopy. No patient will get chemo for a solid tumor without a confirmation of malignancy by a pathologist.
Oh and electronic microscopy (of which you showed an image) is NOT used in the assessment or any cancer.
Lots of young people getting cancer lately. I wonder why…
For profit companies creating food guidelines. Seems pretty straightforward to me.
@@derpatwerknsubbers1680 Yeah, it was a rhetorical question.
@jessicaras4540 Rando
:)
How did you not let Hank present the episode?
Whoo he didn't even touch on the genetic tests for your tumor! your cancer behaves differently based on what part of the DNA is misbehaving, and we can test for "breakable" genes (genetic susceptibility) or even if the DNA has been "broken" in your cells - so your tumor often has slightly different DNA than you, by definition!
Probably too advanced for a layperson 😅
@@lupitasims5209 Beyond the scope of this video, but given what they've explained about astrophysics, I have great optimism for what they can explain!
@jessicaras4540 What is the difference between God and a surgeon?
God knows he is not a surgeon.
Hank should have hosted this episode... sorry.
Wow, what a great AI picture in the thumbnail. Thank god you are embracing the efficiency that AI can offer you. Quantity over quality am I right?
If you're going to sarcastically whinge about an AI generated image, the least you could do is verify it's actually an AI generated image.
Took me a whole 30 seconds to find out it's a Getty stock image made by koto_feja who has a whole portfolio of 3d modeling with Blender.
"Stage zero cancer" doesn't mean you don't have cancer? Why are doctors so bad at naming things?
@jessicaras4540 what is your point?
My preferred letters are E-R-A-D-I-C-A-T-E-D or better yet false positive.
You have Terminal 7, Brain cancer. I don't know what that means. But it's bad.
Is it just me or have cancer rates boomed in the past couple years?
Better diagnosis and more people getting checked out after the pandemic results in a spike. Happened with like everything
Yes, Cancer rates are absolutely on the rise, particularly colorectal and Cervical Cancers in young people
They have grown with the increase in iPhones...and AI....and marijuana use...and eclipses
@@justayoutuber1906 lmao
Va xx
Goodness, is everyone from SciShow getting cancer?
All cancer info from this channel is false unless presented by the man who has personally survived it... HANK!
grammar people. btw your voice has changed what are your new pronouns if I want to comment to you?
It would be nice if a channel that promotes science would ask serious questions about the so-called vaccine and long vaccine and long covid. Develope a little bit of courage. If you really care about science you can’t possibly be ok with the lies we’ve been told.
Not being a crazy merry can I'd be interested to know about these lies 'they' are telling us. Sigh. From my viewpoint from across the pond I honestly think the biggest problem is education, or lack of it. Same things are happening in England (I won't include Scotland, Wales or Northern Ireland) as the USA. Onanists sucked into pseudo science and conspiracy theories. This type of batshit crazy stuff will send America back to the dark ages. I also find it mindblowing that there's a chance the American electorate will vote for The Orange One in November.
Thanks!