Whole-cell patch clamp recording | How does Whole-cell voltage clamp work? | application

This video talks about Whole-cell patch clamp recording. it describes how does Whole-cell voltage clamp work and its application.
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[@annas9942]

Nice explanation. I think it’s also important that cardiomyocytes is a different example of excitable cells and can also be recorded using patch clamp.

[@animatedbiologywitharpan]

i will soon upload a video on cardiac action potential. Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

[@RohitPrajapati-em6fb]

Just amazing explanation

[@animatedbiologywitharpan]

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[@balice8189]

such a well explained video! Thank you!

[@animatedbiologywitharpan]

We are unable to reach big audiance please share our channel link with your friends

[@beinghuman4457]

Sir what is capacitance in case of neuron..or camacitaive component of current ?

[@user-pn8cb8mc4d]

Thanks a lot. I love you.

[@animatedbiologywitharpan]

Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

[@abdullahkabiri2466]

Very useful 👏

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[@robertoguerra5375]

Amazing :D
Do you know whether Neuralink is doing this careful at connections, or is it a more crude way? 😮

[@animatedbiologywitharpan]

I am not sure

[@korkotian]

Dear "Animated biology With arpan", you are mixing up whole cell and cell-attached recordings. For cell-attach, the AMPA current is truly inward at the negative membrane potential. It is because cations flow from the pipette into the cell. But in a whole cell configuration, the same current under the same conditions will look outward, because cations will flow through the channels into the cell and then from the cell into the recording pipette. Thus, if your pipette is clamping voltage at -70 mV, it will begin injecting negative current into the cell in order to compensate the positive shift. This current will be INWARD NEGATIVE, which is equal to OUTWARD POSITIVE. So, the whole-cell pipette will record outward, not inward current.

[@shawnmulberry774]

All your videos are deeply infected by trolls with scams. Too bad you can't seem to get rid of them.

[@animatedbiologywitharpan]

Reported spam for all of them