Neurology | Gustation (Taste Pathway)
ฝัง
- เผยแพร่เมื่อ 8 ก.พ. 2025
- Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
In this lecture Professor Zach Murphy will be teaching you about gustation, or better known as the taste pathway. We hope you enjoy this lecture and be sure to support us below!
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#ninjanerd #Gustation #Taste
Dude this presentation is awesome! Here's why:
You provide a BROAD scope of a certain process. Yet, you are detailed enough to flow through the process logically and without gaps that would impede understanding.
This leaves the learner with new knowledge and far more questions that answers.
Thanks!
Going back to college after 15 years and this gentleman here is the reason I passed the special senses module
Watching your videos first made studying quite easy during med school. Thank you sir!
This guys the truth, his videos make studying the easist
Thank you sir! The pathway is clear now! 🙏
You guy is amazing! I can’t say enough words about my gratitude for sharing.
Thanks for sharing your profound knowledge.
Your skill for explaining is outstanding
This is the best video I've found on the topic of Gustation so far.
Watching your videos first made studying quite easy during med school. Thank you broooooooooo
You're my favorite science teacher!!
Clear, interesting and captivating. Thank you!
Immensely grateful for these videos of yours. 💫
U deserve to be called "Sir Zach "❤️
I always like his videos before starting to watch bcoz i already know it s gonna be great
You are the best teacher I have ever seen
Great video - especially appreciated the clear explanation of the different signaling pathways.
Great job! Complicated subject clearly explained.
Thank you..and by the way, I passed my previous physiology class bcz of you.
I don't know what I could do without your videos❤️❤️
Dude thank you!!! You are so helpful and make it so simple to understand. I would love to buy a ninja nerd shirt, or merchandise.
You are a great teacher Zach
You really helped me understand this information! Thanks!
Appreciation from Tehran dear Zach🙋🏻♀️ cool and useful as always
Assalomu alaykum dear lecturer!
My english vocabulary is not enough to describe how brilliant your lessons are and i am achieving adequate knowledge about whatever you teach. THANKS GOOD LUCK!!!
UR LECTURES ARE AMAZING. THANKU FOR HELPING AND SAVING ME ALWAYYYYYYYSSSSSSS
Excellent explaination sir
No words to describe such a nice explanation Thanks for ur videos 😍
Great lesson! However take care: ATP does not exit the taste cell by vesicles fusion, like in neurons, rather there are specific channels that open (CAHLM1/3) upon depolarisation and let the ATP to exit! Depolarization is mediated by TRPM5 channel that are regulated by Calcium!
That’s was the only mistake you found? There are like seven blatant inaccuracies by minute 3.
@@granthagen3207stop being a dick
Like what? @@granthagen3207
@@granthagen3207 At least this person seems like they’re actually trying to help. You have yet to state a single one of these “blatant inaccuracies”.
Thxx for clearing it out 👍🏻
This guys is a true genius
JazakAllah u khaera!
May Allah reward you with sth better!
Well explained. Thank you!
Is there a way to diagnose the cause of loss of taste for someone, and get treatment? From many years before Covid, of course. I am amazed by this young ninja's level of knowledge!
I think you meant "Gustducin" 11:39. Transducin found inside the Rods and Cones in the eye. Correct me if I`m wrong. Thank you very much for your videos!
yeah, transducin is G protein inside the rod and its for activation of cGMP phosphodiesterase.
Transducin seems also be active in receptors sensitive for bitter taste. Bit literature seems from 1993/1994 (McLaughlin, S. K., McKinnon, P. J., Robichon, A., Spickofsky, N., & Margolskee, R. F. (2007, September). Gustducin and transducin: a tale of two G proteins. In Ciba Foundation Symposium 179‐The Molecular Basis of Smell and Taste Transduction: The Molecular Basis of Smell and Taste Transduction: Ciba Foundation Symposium 179 (pp. 186-200). Chichester, UK: John Wiley & Sons, Ltd..
But I did not spent much time reading.
And additionally Gustducin seems to have another signal pathway with Adenylate cyclase regulating cAMP (according to my pearson book).
th-cam.com/video/xZjlMh-1Crg/w-d-xo.html
Umami! Great Lecture as usual! Thank You Ninja Nerd!
Excellent, you are a book. God bless you and more wisdom.
Very concise summary!
Thank u so much for these tutorials, it helps me understand the book I’m studying “Anatomy Structure and Function “
Wow!!!!,❤️❤️🔥 as always until next time.Much appreciation @ ninjanerds
This was so much help. Thank you so much!
+Keshan Glad it helped, help us out by telling all of your friends about this channel 👍
ninjanerds: "there's very little diseases that could actually cause some type of problem with taste"
corona virus: *enters the chat*
A really annoying virus honestly.......
when he made this video, COVID-19 had not happened
He is correct. Once smell is affected taste follows
@@pacino1stI recall going to a middle school science fair. One young student had cups with various flavored liquids. She had me take a little sip, I tasted it. Then pinch my nose closed and sip from the same cup: no taste! Wow, we need the sence of smell in order to have the sense of taste.
God bless you big! More wisdom and strength I pray for you
Thank you very much. Really well structured and explained Much appreciated!!
Very Good, Zac!!! 👏🏽🤩💯
Thank You ...Wonderful Presentation.
So dedicated. Bravo!
Great Job, Ninja! 💖 God bless u!
You are great Sir
WOW!! It blows my mind .... Thanks :)
I always love your videos, you are getting me through med school! I was laughing when you mentioned that there are very little reasons to lose taste and thought to myself yup this was definitely pre-covid haha. Still suffering from parosmia and associated taste changes myself.... lol
I believe COVID loss of taste, is not related to the gustation pathway but the olfactory pathway, but I could be wrong
Amazingly explained.
Super video. Very much informative
☺ Thank you so much Zach
Fantastic as always!
Nice video, explained in depth.
Very helpful videos. Thank you.
Nice video, but I have some issues, actually, the taste cells associated with bitter, sweet, and umami flavors do not release serotonin, they just release ATP, and ATP is not released trough vesicles, is released trough a voltage-gated channel. Also, the Ca ions do not interact with vesicles in this flavors, they bind to a channel, specificly to the TRPM5 channel wich causes it to open and the Na ions flow into the cell causing depolaration and the subsecuent aperture of the ATP channel that I mentioned before. On the other side, the taste cells asociated with salty and sour tastes do not release ATP, just serotonin.
Williams, S. M., & White, L. E. (2013). Purves, D. et al. (Eds.) (2018). Neuroscience (6e). Sinauer.
According to the most recent literature I could find, you are correct. (Finger, T. E., & Kinnamon, S. C. (2013). A taste for ATP: neurotransmission in taste buds. Frontiers in cellular neuroscience, 7, 264.)
Where is the ATP before it leaves through the voltage gated channel?
It means that the video is wrong?''
@@FreeTheBro the ATP is produced in mitochondria that are squeezed up against the plasma membrane of the taste cell near the connection with the neuron. When those mitochondria produced ATP, it can exit the mitochondrion through pores. The close connection keeps that part of the cytoplasm pretty isolated so it can have a high ATP concentration (replenished by the mitochondria) and if the ATP release channels (CALHM1) is opened, it will exit to stimulate the neuron.
You are wrong :
Scott Herness, in Physiology of the Gastrointestinal Tract (Fifth Edition), 2012
Neurotransmitters in the Taste Bud
TRCs express multiple neurotransmitters and neurotransmitter receptors across selective subsets of cells within the bud. These neurotransmitter pathways include serotonin (5-HT),187,188
...
In mouse TRCs, NE is released from type III cells in response to acid stimulation232 and a small subset of these cells coreleased both serotonin and NE.
...
additionally stimulate type III cells via cell-to-cell communication by activation of P2Y receptors.201 This stimulation may then result in serotonin release from these cells.199
Awesome lecture.
amazing video. wowwww you have helped me so much thank you for your work and effort ! very easy and well expalined :)
Much love Ninja nerd 😂♥️♥️♥️♥️♥️
I do believe Your the best... 👍🏻
perfecttttttt❤❤❤
Dear Sir. Ur way of Teaching is marvelous.
God bless u sir.
Ur are a Real Teacher. U inspire the students so much. To learn and clearly understand the underlaying physiology .
No words to praise ur way of expressing & explaining the science.
Thanks
Thanks Prof God bless you
Thank you so much. God bless you.
YOU'RE THE GOAT!!!!
Your Amazing man thank you so much for your videos
What causes burning mouth syndrome? Your an awesome teacher!
Thank you so much, Sir... ♥♥♥
Msc zoology 4th sem student frm kashmir
Ure teaching skills are amazing sir ❤
Best one out there.
good video. its easy to understand
Thank you VERY MUCH👍👍👍
A perfect explanation!
Great video, but the transduction has some errors. The G protein in sweet/bitter/umami cells is gustducin, not transducin. Also, the receptors do not function as monomers in sweet or umami sensation: they dimerize to initiate transduction. The latter point isn't as important as the former.
Enjoyed!
Wow. You're amazing 💖 Thank you!!!
very helpful!
Thanks
Beautiful!
'sheesha' again - crystal. I understood it very well. Best teaching video on taste sensation
Is the same cell going to consist of multiple types of receptors? If so, how would we distinguish between sweet, bitter, and umami if the same GPCR signal transduction pathway takes place leading to an action potential from the same receptor cell?
the receptors are mainly present on distinct cells!
My question exactly!
Beautiful..thank you so much
great informative
U R THE BEST
Thankyou so much sir
Thank you 🙏
THANK YOUUUU SOOO MUCH!!!!!!!!
Thanks a lot 😊
Thanks❤
Very good videos.. very helpful !!!👍
Hey Zach, a classmate of mine just got me onto your videos and I just wanted to let you know that I think they are absolutely awesome. I just wanted to ask; around 11:55 you talk g-protein transducin and in my textbook it shows gustducin...so I am wondering which one is correct here? Thanks so much!
Very helpful, thanks a lot from Palestine ..
best video...very detailed!
Luv u channel..❤
Plz upload more videos like this
👍
Thank you
very clear thank you
so good!!
THANK YOU 💯
Thnq so much sir
Just blew my mind that umami taste buds respond to glutamate. Explains why MSG adds so much flavor to foods
Am I the only one who can't get over how smart this man is???
My God! 🥵🥵🥵
amazing