Cell Adaptations: pathology:HYPERTROPHY HYPERPLASIA AND METAPLASIA

A series of video tutorials discussing the pathology of cell injury and adaptations.
In this tutorial , i have discussed Hypertrophy, Hyperplasia and Metaplasia.
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HYPERTROPHY
Increase in the SIZE of the parenchymal cells
increase in the size of the organ
Cause :
Increased functional demand or
Stimulation by hormones and growth factors
Mechanisms :
Increased production of cellular proteins.
Due to the increased activation of genes responsible for the production of these proteins
sometimes a subcellular organelle may undergo selective hypertrophy
Eg: patients on barbiturates show hypertrophy of the smooth endoplamic reticulum (ER) in hepatocytes.
HYPERPLASIA
Increase in the NUMBER of cells in an organ
It takes place if the cell population is capable of dividing
Mechanism :
Results from growth factor induced proliferation of mature cells or
Increased output of new cells from stem cells.
METAPLASIA
It is a reversible change
in which one differentiated cell type (epithelial or mesenchymal) is replaced by another cell type
Mechanism
Due to REPROGRAMMING of the precursor cells, present in the normal tissues.
Differentiation into a new cell lineage
By signals generated by various cytokines, growth factors, and extracellular matrix components in the cells' environment.
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Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"
• NEOPLASIA 6: WARBURG E...
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[@drdwgmd14]

Your video was reqlly good, because of this, I passed my cell biology midterm!! Please, please make more. My hero

[@KaviaABerry]

this video was quite helpful , thank you so much and may God bless you!

[@shresthade7036]

What a helpful video! thank you so much 😀

[@alejandrachavesromero8605]

I just love the video, thank you!!

[@bewuketlamesgin9993]

am from ethiopia your presentation,explanation is gorgeous thank you very much

[@ashishbeniwal8718]

Fabulous explanation sir ,ty so much 👍👍

[@vaisshnavi1257]

Pathology is cake walk with your lectures 🙇‍♂️🙇‍♂️🙇‍♂️🙇‍♂️🙇‍♂️

[@ilovepathologyVijayPatho]

Thank you 😊

[@Allhamdolillah2]

Thank You so Much 💟 Quite Beneficial 🤓

[@minnahahamed9069]

Very concise and clear explanation. Waiting for all pathology lectures from all chapters. Thank you sir

[@muhammedfaruk9022]

Really good videos. Thanks a lot. This made studying very easy. Can you please add subtitles to your videos. Thanks again.

[@sahtianwar1531]

Wow finally got what i was searching for 💙
If just as me you are covering your pathology for Robins these videos are really what you need to watch.
Loved it cox it's covering all points and even adding certain extra points 💕

[@ilovepathologyVijayPatho]

Thanks Sahti Anwar.. Glad you liked it:-) please do share

[@YousefRaysis]

Thanks man
👍🏻👍🏻

[@tvyshali7498]

Thank u sir it is very useful video thank u very much

[@thescientifichindu7588]

Sir please make videos covering all pathology chapters..

[@jaishree5808]

Yes

[@charmirathod2954]

Thank you for easy understanding

[@marijasavic4797]

Good explanation, just a suggestion, maybe you should add atrophy here as well as forth mechanism of adaptation. :)

[@bhavrchoudhry4392]

yeah bro other than this very nice and understandable explanation

[@thebackbencher7206]

Thank you sir

[@supunidissanayake7307]

soothing voice 🤩

[@kumarsumitstudentbsmu.cher6558]

really nice video sir

[@surajmonimurmu3705]

Make more vedioes sir... It's very helpful to me

[@anshasmith6936]

Perfect!!bless you indea it's from USA. Brilliant teachers

[@pushkar6096]

It's India

[@anshasmith6936]

@@pushkar6096 hehe it's okey some times to make a mistake thanks.

[@EstherIkede]

Thank you!!

[@drtoothkrk]

Very use full videi sir

[@harshitaborasi3841]

Sir your videos are really great the way you explain the mechanism through flow charts is so good ...I would like it if you cover the rest topics of pathology.

[@happygamer1714]

You video is really good sir..please you could kindly do a video on kidney changes in shock or refer me to an online....thank you

[@veta3093]

Thank you sir..

[@kpzcbttp]

I have been diagnosed as having hypertrophy of the colon. I can tell you the pain is always there and felt at different levels and when bending forward I can feel a kind of firm area just above my belly button and a it over to the right. Had all the tests, but, just have to live with it.

[@dr.salmabnys4655]

kpzcbttp try naturopathy it will help h

[@hirasaleem5378]

Hello, are you okay now? Is there any other diagnosis?

[@iqrashaik8]

thank you sir...it's very helpful..👍

[@rituagrawal3343]

you have written about metaplasia that "one differentiated cell type is replaced by another cell type" than u said the precursor cells are transformed
and as much i know differentiated cells and precursor cell are two different type of cell
please help me out with this confusion.
btw your vedio is really helping😍😍

[@fidha3398]

The precursor cells produce the new cell type and progressively replace the older ones.. as you can see in some histopathology slides of Barrett's oesophagus, where there is intestinal metaplasia below layers of squamous epithelial cells.

[@tejaswitaacharya1831]

Too good..

[@selflove1999]

Sir pls do a video on the topic of dysplasia

[@latifamohammed2355]

Well understood

[@ashuhooda1012]

thank u sir

[@juansamudio1171]

Does Hypertrophy and Hyperplasia occur at the same time and if so how does that happen if we are building muscle but hyperplasia cannot occur in muscle cells?

[@positivevibes7425]

Sir are these adaptations reversible?

[@anvithabadekkila3786]

Plz upload topics on bone pathology

[@bharathrajaram1696]

In metaplasia what happens to the already existing cells

[@AbdulAzeez-jd3ht]

My CT scan reports of brain old. Infarc in the left capsule. Is it a serious concern? what is the medicine fo it. I’m already taking clopilet &50mg and atevostatin

[@bashairalhidri5955]

Thanks

[@ashokkumarsahu304]

Thanks so much for this information

[@veronicabridget6631]

Excellent!

[@Ijhaytrix]

What is is secretory metaplasia

[@justatry100]

Everything is good but the introduction tune is like mental torture

[@ilovepathologyVijayPatho]

😃😃😃🤦 no more of torture in the recent videos

[@rajatpandey4302]

I have left kidney hypertrophy. Is this dangerous

[@prabhakarwadhwani1026]

Harsh mohan

[@stclassicalchannel3716]

Sir Your teaching speed is very fast

[@shivappagaddadavarayurvedi8265]

Sir you must take the white board to explain to us otherwise not understand

[@rob5psv]

Are there people that believe in hyperplasia or have experience with it?

[@navitameena6832]

Sir ji please notes bhi provide kare

[@Gb-vc8de]

What is m to G1

[@jiyaworld1407]

th-cam.com/video/xOONFDNI_aE/w-d-xo.html
Check more pathology vedios :)

[@dineshprasad1580]

Mitosis to g1 stage

[@jaishree5808]

@@dineshprasad1580 G1,G0 means

[@parshuramsoni1170]

Very well teaching

[@rahuja3872]

Your voice is same as that of pankaj kapoor

[@ilovepathologyVijayPatho]

:-)

[@099yuvarajkumar8]

Atrophy ?

[@pheonixheart5534]

💜💜💜🏌️‍♀️

[@anooprana7115]

Hindi me video bna sakte hai kya sir

[@promisemakhubele1570]

damn you are too fast try to speak slow

[@supunidissanayake7307]

soothing voice 🤩

[@ReshamPal-ud2tt]

Thank you sir