Making and Testing The ANTI-SPICY Molecule (Capsazepine)

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  • เผยแพร่เมื่อ 21 ก.ย. 2024
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    In this video I am making and self-testing the molecule Capsazepine (albeit crude), a molecule that blocks access to the receptor activated by the spicy-molecule capsaicin, thus removing its ability to cause you the spicy feeling. There is no known literature on its use on humans, it is used to study the TRPV1 ion-channel (spicy/heat receptor) but only in biology or biochemistry.
    For the azepine: onlinelibrary....
    For the isothiocyanate I used a general procedure from: scihub.se/http...
    For the final coupling: sci-hub.se/htt...
    Support my channel with patreon:
    / chemiolis
    Check out @LabCoatz_Science who notified me of this molecule.
    This video is sponsored by Curiosity Stream.

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