What an amazing story. There are so many more potential survivors of cancer with more genetic profiling. I cannot understand why full characterization of a tumor is not part of standard of care. I am so happy for Diane, with whom I identify so strongly. I also have two grandsons, a Brittany, and our family has been touched by ovarian cancer with the more typical outcome. To Diane - if you see this, I wish you many more years with your family. Enjoy every day. Your story is inspiring.
Diane always have hope. I had an ovarian tumor the size of a football. The cancer never spread outside the tumor, and the tumor wasn’t wrapped around anything. They did a debulking and removed my appendix. I had no chemo or radiation and was home in two weeks. I said this healing prayer over and over. Thy name is my healing, O My God, and remembrance of the is my Remedy. When they brought me to my room there sat a beautiful bottle of lotion and across the top it said “Remedy “. Their is a long healing prayer by Baha’u’llah and it is the most powerful prayer for healing. It’s called “The Long Healing Prayer “ by Baha’u’llah. I wish you all the best. From one friend to another.
I was wondering the same...I had most of my tumors removed but they weren't molecular profiled.... However, I took a blood test for the BRCA mutation, still waiting on the results but my oncologist ordered the immunotherapy anyways.
Dear Crystal and PCT - when you do genetic profiling from the cells lining your mouth, with a cotton swab, you are profiling your healthy genetic profile. The DNA in the cells from that collection is your inherited DNA and the DNA you will pass to your children. The purpose of that analysis is to help you to know if you have an increased risk of getting cancer or if you can pass an increased risk to your children due to mutations in genes that are known to have that effect, like oncogenes BRCA1, EGFR and RAS, and tumor suppressor genes like P53 and RB. When you do a genetic profile of tumor tissue, you are looking specifically at unhealthy tissue, not representative of your inherited genes. The tumor is genetically different from your normal tissue due to accumulated mutations. From your tumor's genetic profile, you want to learn what is it that is unique to this tissue that makes it grow so much more aggressively than normal healthy tissue. If you do find an "actionable mutation", it is like having a key to the lock, like the mutation in the BRCA gene that Diane reported, and you can participate in a therapy that targets just that gene, and ideally just kills your tumor cells. It was surprising that in Diane's case, she had a somatic BRCA mutation. BRCA is also a cause of inherited cancer, but in this case it was not. It was just in the tumor and could be targeted for therapy. This is a amazing story of the benefit of molecular characterization. Sometimes there are no keys to the cancer therapy; however, the more cancer patients that have their tumor characterized, who share their medical history, the more keys we will identify and the more stories like Diane's we will celebrate.
So glad you survived cancer! I also am a Ovarian cancer survivor. It was caught early so only had to do 3 rounds of chemo. ❤
How are you now Ma'am
What an amazing story. There are so many more potential survivors of cancer with more genetic profiling. I cannot understand why full characterization of a tumor is not part of standard of care. I am so happy for Diane, with whom I identify so strongly. I also have two grandsons, a Brittany, and our family has been touched by ovarian cancer with the more typical outcome. To Diane - if you see this, I wish you many more years with your family. Enjoy every day. Your story is inspiring.
genetic profiling of a patient's cancer is standard of care.
@@anglophils645 That does not seem to be the experience of most cancer patients I speak to. Can you provide more details?
I'm so glad you took the time and energy to do this
"The right drug for the right patient in the right time" Let`s do this Dr. Darus!!!!!! / Good luck for so many years to come Diane!!!! 🌼
Diane always have hope. I had an ovarian tumor the size of a football. The cancer never spread outside the tumor, and the tumor wasn’t wrapped around anything. They did a debulking and removed my appendix. I had no chemo or radiation and was home in two weeks. I said this healing prayer over and over. Thy name is my healing, O My God, and remembrance of the is my Remedy. When they brought me to my room there sat a beautiful bottle of lotion and across the top it said “Remedy “. Their is a long healing prayer by Baha’u’llah and it is the most powerful prayer for healing. It’s called “The Long Healing Prayer “ by Baha’u’llah. I wish you all the best. From one friend to another.
How do I find this. Could you write it for me to say for mum. I've looked on Google but its lots of different things and want correct one. Thank you 😊
My tumor was bigger - and I didn’t do chemo either.
@@monicag6715 That’s amazing, glad you survived such a scary ordeal
May God give you great health
Diane I wish you continued health and happiness
I have a question: what is the difference between genetic profile by cotton swab mouth lining and genetic profile by tumor tissue? Are they the same?
I was wondering the same...I had most of my tumors removed but they weren't molecular profiled....
However, I took a blood test for the BRCA mutation, still waiting on the results but my oncologist ordered the immunotherapy anyways.
Dear Crystal and PCT - when you do genetic profiling from the cells lining your mouth, with a cotton swab, you are profiling your healthy genetic profile. The DNA in the cells from that collection is your inherited DNA and the DNA you will pass to your children. The purpose of that analysis is to help you to know if you have an increased risk of getting cancer or if you can pass an increased risk to your children due to mutations in genes that are known to have that effect, like oncogenes BRCA1, EGFR and RAS, and tumor suppressor genes like P53 and RB.
When you do a genetic profile of tumor tissue, you are looking specifically at unhealthy tissue, not representative of your inherited genes. The tumor is genetically different from your normal tissue due to accumulated mutations. From your tumor's genetic profile, you want to learn what is it that is unique to this tissue that makes it grow so much more aggressively than normal healthy tissue. If you do find an "actionable mutation", it is like having a key to the lock, like the mutation in the BRCA gene that Diane reported, and you can participate in a therapy that targets just that gene, and ideally just kills your tumor cells. It was surprising that in Diane's case, she had a somatic BRCA mutation. BRCA is also a cause of inherited cancer, but in this case it was not. It was just in the tumor and could be targeted for therapy. This is a amazing story of the benefit of molecular characterization.
Sometimes there are no keys to the cancer therapy; however, the more cancer patients that have their tumor characterized, who share their medical history, the more keys we will identify and the more stories like Diane's we will celebrate.
And my mom had ovarian cancer.
I wish you well
How they test this gene?