If you cannot explain it easy you have not understood it well enough. This immensely talented lovely Lady scientist & orator is a bright example of it.
Congratulations 🎉 Carolyn for winning the 2022 Nobel prize in chemistry and God bless you that you should increase in your life for more I am poor in English but I can understand your lecture
She speaks so well! The crowd seems dead. I really love the enthusiasm she brings to the lecture, it amazes me profoundly everything that biology has uncovered in recent years.
We know that the western diet has massively increased amounts of sugar over the past four or five decades while we've also seen a rise in cancer, could restricting sugar and carb intake deprive that jungle from getting established in the first place? I'm a two time cancer survivor and looking at different diets to promote health and wellness. Right now I've been doing keto for about 3.5 months and feeling awesome.
The answer to that question is no. Sugars are a class of molecules. The sugars you are referring to are glucose and fructose, etc. more likely is that things just don’t kill us as often as they used to, hence more cancer. Don’t spread misinformation 😊
As a south asian student who has been in the US for a year now and is horrified by your food taste and habit, just cut everything that is manufactured from industry. Literally everything. Cook in home and avoid canned or readymade food that is so prevalent in your western diets. Also donuts and pancakes are not breakfast, so don’t treat them as breakfast. Take a hearty and healthy meal instead. May be some rice with meat, fish and vegetables. Or may be make some homemade bread from wheat flours or any kind of flours. It would take a lot of time but it’s worth it cause your health is the most important asset that you have.
@@tommykelly6840 Asking a question, which you can tell she did by this (?), is not spreading misinformation. She's asking for information on the subject, which you did an excellent job of providing.
I started listening and thought she would tell us how to reduce sugar coating of the cells to prevent the disease in the first place. Today's medicine is not interested in prevention. But wait, wonderful, there will be another drug to take instead, wow!
exquisite lady , elegant, funny and eficient communicator👏 ; I am greatful you won Nobel because due to this I discovered you in the news and your knowledge will stay with me forever, I will not let you go from now on😉
Perhaps not eating the carbs (sugar - glucose/fructose) in the first place might be a better suggestion because Carbohydrates directly cause diabetes, obesity, cancer, heart disease, liver disease and dementia.
It helps, but there is a shit tonne of pathways for glucose creation... Glutamine, pentose phosphate pathway, lol even fking lactic acid which cancer cells create thus allowing there own energy formation, but! Lowing carbs and getting rid of linoleic acid is a start.
industrial sugar is NOT a food: it's a very much like an edible glue, when completed with industrial grains for a long time they are overtaking metabolism, burning out biochemical responsiveness of the immunologic capacity. precision medicine is the strong strategy for health care. industrial grains were meant to fight post WWII decades of hunger, and not ever to become the only self-rewarding competitive offer at the market store.
My question would be why is a cancer cell, which is supposed to be just a normal cell that went off the rails, using methods to cloak itself, kind of like a predatory organism? It seems less like an accidental mutation than it does a purpose driven event.
You ndon't seem to have had your graduate studies, long, long, long ago!!!You don't even seem to have had face lifting!!! Now we have a young beautiful Nober prize winner...Bravo.
It’s not just the outside of the cell that is important. The metabolism of the cancer cells require plenty of glucose, since their energy production is through fermentation rather than oxidative phosphorylation, which provides the energy for all of the normal cells of the body. By reducing sugar and carbohydrates, the Insulin levels will eventually reduce to normal. Raised Insulin levels are the cause of many man made ‘diseases’…!!
Three years later at Palleon you only into phase 1 trials of 1 of your 4 drugs. E-602. Take your time no rush! Today's date is 20/11/2022. Let's see how long it takes! Everyone laughed at Aspirin (Sialic acid) for 30 yrs. Yet here we are!
कैरोलीन बरटोजी मैडम आपने जो पक्ष रखा उसमें नार्मल सैल पर भी शुगर कोटींग होती हैं इनफैक्ट आपने कहा सब सैल्स पर शुगर कोटींग होती हैं परंतु कैंसर सैल्स में सियैलीक एसीड बढ़ जाता हैं ऊपरी परत पर। कुछ पौधों में टोटीपोटैंसी का गुणधर्म होता हैं जिससे पौधे के सभी सैंल बन जाते हैं चाहे मैंरीस्टमैंटीक हो चाहे पैरनकाइमल हो चाहे वसकुलर बड़ल हो चाहे स्ट्रोंमा या ग्रैंना हो। हम देखते हैं गन्ने के नोडस में केवल एसे मैंरीस्टमैंटीक सैल पाये जाते हैं जबकी इंटरनोड़स पर अनुपस्थीत होते हैं। नये बड्स नोड से निकलते हैं इंटरनोड से नहीं और गन्ना पूरे विश्व में शुगर चीनी बनाने के लिए उपयोग किया जाता हैं। हमें नारमल ग्रोंथ और ओवर ग्रोंथ/कैंसर में अतंर समझना होगा। ज्यादा यूरीया देने से पौधों की ओवरग्रोंथ मतलब वैजीटेटीव ग्रोंथ होती हैं और गन्नै की शुगर मात्रा घट जाती हैं। हर पौधे के सैंल कार्बन डाइआक्साइड को फीक्स करके और पानी उपयोग कर C6H12O6/शुगर और 02 बनाते हैं। पौधा तो ज्वार का भी होता हैं और उसे हम जानवर को खिलाते हैं और वह दुध देता हैं जिसमें लैक्टोज़ शुगर होती हैं और लैक्टोबैसिलस बैक्टीरीया उसको फरमनटेशन द्वारा तोड़ कर दही में बदल देता हैं जो एसीडलैक्टीक से टाक दही खट्टी बदल जाती हैं। यहां मिष्टी दोई भी मिलती हैं। हमें उन बैक्टीरीया की खोज करनी चाहिए जो सियैलीक एसीड शुगर को अपना भोजन बनाए। आपने कहा यह सियैलीक एसीड खतरनाक नहीं हैं वरना तो अवर स्टोमक एसीड (Hcl fundic secretion) इज स्ट्रांग इनफ टू डीजौलव रेजर ब्लेड्स। हम हरबीवोर न होकर ओमनीवोर हैं भले ही सैल्युलोज डायजैस्ट न कर पाये कौम्पलैक्स शुगर सैलाइवा के टायलिन ptylin और salivary amylase द्वारा टूट जाता हैं। एमाउंट आफ सैलाइवा वी प्रोडयूस इनक्रीजेंज सडनली वैंन वी वोंमीट टू प्रोटैक्ट अवर टीथ फ्राम द एसीड इन अवर स्टोमक दैट कमस अप। ज्वार के पौधे में HCN धुरीन DHURIN होता हैं जो मक्का धान गेहूं के पौधे में नहीं होता। किसानों के लिए धुरीन मित्र भी हैं और शत्रु भी। धुरीन ज्वार को कीट आक्रमण से बचाता हैं और कीट की ओलफैक्टरी पांव में होती हैं और एक कीट सिग्नल भेजकर एंटीना से दुसरे कीट को आगाह करता हैं मरते मरते की पत्ते मत खाना वरना सब मारे जाओंगे। दूसरी तरफ जानवर ज्वार ज्यादा खाले तो HCN से मारे जाते हैं। अमरीका में मैंड़ काउ डीजीज होती हैं परंतु भारत में नहीं। Mammalian intestines contain multiple glucosidases which efficiently hydrolyze glycosidic bonds. Upon hydrolysis of the glycosidic bond, the aglycone of dhurrin rapidly degrades to form hydrogen cyanide which is then absorbed into the bloodstream. In arid environments, sorghum is the best option for cereal grain and fodder as it can withstand extreme drought conditions.Animals consuming the raw sorghum as fodder are much more likely to eat an amount that would contain a lethal dosage of dhurrin for their respective species and can result in animal loss due to hydrogen cyanide poisoning. कभी कभी एसा मेरे दोस्त कहते थे कि दिमाग की बती जलाने के लिए बिड़ी सुलगाओं परंतु मैं कहता था कि बत्ती फिर भी न जले तो। कहते थे जरूरी नहीं की बिजली की स्पलाई हो ही और ट्युबलाइट न जले हो सकता हैं तुमने स्टार्टर ही नहीं लगाया या चोक खराब हो या बिजली हो परंतु तार में डीफैक्ट हो और ट्युबलाइट तक न पहुंचे कुछ भी हो सकता हैं। इंसुलीन रैजीस्टैंस में सैल के भीतर ग्लुकोज कैसे पहुंचेगा। गलुकोज तो शरीर में बना हैं परंतु इंसुलिन नहीं तो सैल तक कैसे पहुंचेगा। पावर हाउस आफ सैल माइटोकौंड्रीया पर ग्लुकोज नहीं पहुंचेगा तो पावर कहा रहेगी। बिजली/ग्लुकोज की उर्जा किसी की जान(कैंसर)भी ले सकती हैं और वहीं उर्जा ट्युबलाइट को जला कर रोशनी से अंधकार भी मिटा सकती हैं। कभी कभी क्लास में बच्चे कहते थे पुरोहित की ट्युबलाइट देर से जली और मैं कहता था शुक्र हैं जली तो।
Lecturing with metaphors ‘may make a simple talk easier to comprehend’, however metaphors are a cop out to in-depth understanding of a concept…and worse yet…relying on metaphors for teaching to a general audience introduces a myriad of misconceptions. Read…How People Learn, 2nd Ed.
10:05 Companies need to stop copying the GameCube logo. The NFT/BC effort Polium One was called out for basically ripping off the GameCube logo (by rotating it 90 degrees clockwise). Palleon's logo looks nearly identical to Polium One's logo. Also, after the nonsense with Theranos, people should be very leery of another university-incubated start-up claiming miracles.
9:32 Interesting., I've always been able to detect the true character behind every face., this is why if I have to pretend at being human, I choose solitude and celibacy.🤣
Congrats Carolyn for winning the 2022 Nobel Prize in Chemistry!
She is a super great teacher, using simple way to explain, it is a enjoy to listen to her.
Wow! She brings Chemistry to a level that anyone can understand
That’s how you know someone really understands something.
If you cannot explain it easy you have not understood it well enough. This immensely talented lovely Lady scientist & orator is a bright example of it.
Congratulations 🎉 Carolyn for winning the 2022 Nobel prize in chemistry and God bless you that you should increase in your life for more I am poor in English but I can understand your lecture
She speaks so well! The crowd seems dead. I really love the enthusiasm she brings to the lecture, it amazes me profoundly everything that biology has uncovered in recent years.
Congratulations Prof. Carolyn Bertozzi for winning the 2022 Nobel prize in chemistry.
Congrats on winning the Nobel prize 2022 .
These are the people we need to idolize, not some rich sports or movie stars.
Carolyn, you have done an unthinkable job, and Cograts!
No wonder she won the Nobel prize in chemistry yesterday 😌
We know that the western diet has massively increased amounts of sugar over the past four or five decades while we've also seen a rise in cancer, could restricting sugar and carb intake deprive that jungle from getting established in the first place? I'm a two time cancer survivor and looking at different diets to promote health and wellness. Right now I've been doing keto for about 3.5 months and feeling awesome.
The answer to that question is no. Sugars are a class of molecules. The sugars you are referring to are glucose and fructose, etc.
more likely is that things just don’t kill us as often as they used to, hence more cancer. Don’t spread misinformation 😊
Healthy carbs protect against cancer.
This has nothing to do with dietary sugar
As a south asian student who has been in the US for a year now and is horrified by your food taste and habit, just cut everything that is manufactured from industry. Literally everything. Cook in home and avoid canned or readymade food that is so prevalent in your western diets. Also donuts and pancakes are not breakfast, so don’t treat them as breakfast. Take a hearty and healthy meal instead. May be some rice with meat, fish and vegetables. Or may be make some homemade bread from wheat flours or any kind of flours. It would take a lot of time but it’s worth it cause your health is the most important asset that you have.
@@tommykelly6840 Asking a question, which you can tell she did by this (?), is not spreading misinformation. She's asking for information on the subject, which you did an excellent job of providing.
She explains so beautifully, she makes learning fun
I started listening and thought she would tell us how to reduce sugar coating of the cells to prevent the disease in the first place. Today's medicine is not interested in prevention. But wait, wonderful, there will be another drug to take instead, wow!
And, surprise, it will bankrupt you.
She was talking about the Nobel prize winners from 2018 and did not realized she’s one of them in 2022!
She has explained it so so well. I've understood
4:55
Fenbendazol?
Eating raw onions, garlic, ginger and cilantro?
Medicinal mushroom tinctures?
Turkey Tail, Chaga, Reishi, Lion's Mane., etc?
This is really interesting! Plus I just enjoyed the narration, brilliantly said!
I wonder if this is why chemo is so much more effective when cancer patients fast before, during and after treatment.
ive been fasting half my life it helps the fight for sure
exquisite lady , elegant, funny and eficient communicator👏 ; I am greatful you won Nobel because due to this I discovered you in the news and your knowledge will stay with me forever, I will not let you go from now on😉
I just happened upon your 2 wonderful lectures from 12 years ago, the ones about the glycome, and then came here.
CONGRATULATIONS!
Congratulations and the best of luck in this wonderful advance
Her teaching is very clear. No more died for cancer
Thank you for your work
Great speaker. I have forgotten that I am listening it online😃
It's really amazing to listen prof Bertozzi
Perhaps not eating the carbs (sugar - glucose/fructose) in the first place might be a better suggestion because Carbohydrates directly cause diabetes, obesity, cancer, heart disease, liver disease and dementia.
It helps, but there is a shit tonne of pathways for glucose creation... Glutamine, pentose phosphate pathway, lol even fking lactic acid which cancer cells create thus allowing there own energy formation, but! Lowing carbs and getting rid of linoleic acid is a start.
industrial sugar is NOT a food:
it's a very much like an edible glue, when completed with industrial grains for a long time they are overtaking metabolism, burning out biochemical responsiveness of the immunologic capacity.
precision medicine is the strong strategy for health care.
industrial grains were meant to fight post WWII decades of hunger, and not ever to become the only self-rewarding competitive offer at the market store.
not to mention that your healthy cells still need sugars too
@@ezrahn they don't need processed sugar, sugar is in all foods in other forms, also the liver can make a healthy sugar on its own.
What’s wrong with linoleic acid foods?
My question would be why is a cancer cell, which is supposed to be just a normal cell that went off the rails, using methods to cloak itself, kind of like a predatory organism? It seems less like an accidental mutation than it does a purpose driven event.
Stress, PTSD, diet, environmental exposures, etc.
You ndon't seem to have had your graduate studies, long, long, long ago!!!You don't even seem to have had face lifting!!! Now we have a young beautiful Nober prize winner...Bravo.
Great talk!
Congrats~!
So inspiring!
10:00 pause hell yes brilliant congratulations well deserved Nobel!!! saving our lives :}*
It stands to reason that reducing sugar intake would diminish cancer cells’ ability to grow their deceptive lawn.
No offense man but that's some ancient Greek level of reasoning.
@@GretcieI agree with Audioonmusic
Wow!! This is just incredible!!
Ironic how you said nothing bad about the consumption of sugar and its role on cancer cells
Because Salic acid is not a simple sugar like that which you put in your coffee/tea.
@@Brigidz Sugar is sugar. Get over yourself, son.
@@Brigidz are you arguing that common sugar has no effects on the development of cancer?
It’s not just the outside of the cell that is important.
The metabolism of the cancer cells require plenty of glucose, since their energy production is through fermentation rather than oxidative phosphorylation, which provides the energy for all of the normal cells of the body.
By reducing sugar and carbohydrates, the Insulin levels will eventually reduce to normal.
Raised Insulin levels are the cause of many man made ‘diseases’…!!
It if all our cells are covered in sugar how do we know we’re are “mowing” the sugar only on the cancer cells? Location?
Outstanding!!!!!!
CONGRATULATIONS Chemistry Nobel Prize Winner 2022!!! 🇺🇸🐕🎩🏆📯💯🇺🇸
Now if you tell your patients to eat a low carb diet there will be less sialic acid on those cells right?
Such heroic work, thanks to these geniuses we might one day have universal medecine for it! I hope it happens soon.
This video was created 3 years ago. I wonder how the medicine is working.
So what happened to the year?
Three years later at Palleon you only into phase 1 trials of 1 of your 4 drugs. E-602. Take your time no rush! Today's date is 20/11/2022. Let's see how long it takes! Everyone laughed at Aspirin (Sialic acid) for 30 yrs. Yet here we are!
कैरोलीन बरटोजी मैडमजी नोबेल जीतने की बहुत बहुत बधाई।
Beautiful and charismatic italian woman.
Brasil
And what about the sialic acid eerywhere else in the body??
कैरोलीन बरटोजी मैडम आपने जो पक्ष रखा उसमें नार्मल सैल पर भी शुगर कोटींग होती हैं इनफैक्ट आपने कहा सब सैल्स पर शुगर कोटींग होती हैं परंतु कैंसर सैल्स में सियैलीक एसीड बढ़ जाता हैं ऊपरी परत पर। कुछ पौधों में टोटीपोटैंसी का गुणधर्म होता हैं जिससे पौधे के सभी सैंल बन जाते हैं चाहे मैंरीस्टमैंटीक हो चाहे पैरनकाइमल हो चाहे वसकुलर बड़ल हो चाहे स्ट्रोंमा या ग्रैंना हो। हम देखते हैं गन्ने के नोडस में केवल एसे मैंरीस्टमैंटीक सैल पाये जाते हैं जबकी इंटरनोड़स पर अनुपस्थीत होते हैं। नये बड्स नोड से निकलते हैं इंटरनोड से नहीं और गन्ना पूरे विश्व में शुगर चीनी बनाने के लिए उपयोग किया जाता हैं। हमें नारमल ग्रोंथ और ओवर ग्रोंथ/कैंसर में अतंर समझना होगा। ज्यादा यूरीया देने से पौधों की ओवरग्रोंथ मतलब वैजीटेटीव ग्रोंथ होती हैं और गन्नै की शुगर मात्रा घट जाती हैं। हर पौधे के सैंल कार्बन डाइआक्साइड को फीक्स करके और पानी उपयोग कर C6H12O6/शुगर और 02 बनाते हैं। पौधा तो ज्वार का भी होता हैं और उसे हम जानवर को खिलाते हैं और वह दुध देता हैं जिसमें लैक्टोज़ शुगर होती हैं और लैक्टोबैसिलस बैक्टीरीया उसको फरमनटेशन द्वारा तोड़ कर दही में बदल देता हैं जो एसीडलैक्टीक से टाक दही खट्टी बदल जाती हैं। यहां मिष्टी दोई भी मिलती हैं। हमें उन बैक्टीरीया की खोज करनी चाहिए जो सियैलीक एसीड शुगर को अपना भोजन बनाए। आपने कहा यह सियैलीक एसीड खतरनाक नहीं हैं वरना तो अवर स्टोमक एसीड (Hcl fundic secretion) इज स्ट्रांग इनफ टू डीजौलव रेजर ब्लेड्स। हम हरबीवोर न होकर ओमनीवोर हैं भले ही सैल्युलोज डायजैस्ट न कर पाये कौम्पलैक्स शुगर सैलाइवा के टायलिन ptylin और salivary amylase द्वारा टूट जाता हैं। एमाउंट आफ सैलाइवा वी प्रोडयूस इनक्रीजेंज सडनली वैंन वी वोंमीट टू प्रोटैक्ट अवर टीथ फ्राम द एसीड इन अवर स्टोमक दैट कमस अप। ज्वार के पौधे में HCN धुरीन DHURIN होता हैं जो मक्का धान गेहूं के पौधे में नहीं होता। किसानों के लिए धुरीन मित्र भी हैं और शत्रु भी। धुरीन ज्वार को कीट आक्रमण से बचाता हैं और कीट की ओलफैक्टरी पांव में होती हैं और एक कीट सिग्नल भेजकर एंटीना से दुसरे कीट को आगाह करता हैं मरते मरते की पत्ते मत खाना वरना सब मारे जाओंगे। दूसरी तरफ जानवर ज्वार ज्यादा खाले तो HCN से मारे जाते हैं। अमरीका में मैंड़ काउ डीजीज होती हैं परंतु भारत में नहीं। Mammalian intestines contain multiple glucosidases which efficiently hydrolyze glycosidic bonds. Upon hydrolysis of the glycosidic bond, the aglycone of dhurrin rapidly degrades to form hydrogen cyanide which is then absorbed into the bloodstream. In arid environments, sorghum is the best option for cereal grain and fodder as it can withstand extreme drought conditions.Animals consuming the raw sorghum as fodder are much more likely to eat an amount that would contain a lethal dosage of dhurrin for their respective species and can result in animal loss due to hydrogen cyanide poisoning. कभी कभी एसा मेरे दोस्त कहते थे कि दिमाग की बती जलाने के लिए बिड़ी सुलगाओं परंतु मैं कहता था कि बत्ती फिर भी न जले तो। कहते थे जरूरी नहीं की बिजली की स्पलाई हो ही और ट्युबलाइट न जले हो सकता हैं तुमने स्टार्टर ही नहीं लगाया या चोक खराब हो या बिजली हो परंतु तार में डीफैक्ट हो और ट्युबलाइट तक न पहुंचे कुछ भी हो सकता हैं। इंसुलीन रैजीस्टैंस में सैल के भीतर ग्लुकोज कैसे पहुंचेगा। गलुकोज तो शरीर में बना हैं परंतु इंसुलिन नहीं तो सैल तक कैसे पहुंचेगा। पावर हाउस आफ सैल माइटोकौंड्रीया पर ग्लुकोज नहीं पहुंचेगा तो पावर कहा रहेगी। बिजली/ग्लुकोज की उर्जा किसी की जान(कैंसर)भी ले सकती हैं और वहीं उर्जा ट्युबलाइट को जला कर रोशनी से अंधकार भी मिटा सकती हैं। कभी कभी क्लास में बच्चे कहते थे पुरोहित की ट्युबलाइट देर से जली और मैं कहता था शुक्र हैं जली तो।
So what is your message? Stop eating sugar?
I wish the message of the video would be Eat Less Sugar. Then I would. Seriously.
Lecturing with metaphors ‘may make a simple talk easier to comprehend’, however metaphors are a cop out to in-depth understanding of a concept…and worse yet…relying on metaphors for teaching to a general audience introduces a myriad of misconceptions. Read…How People Learn, 2nd Ed.
But the drug did not work, right?
10:05 Companies need to stop copying the GameCube logo. The NFT/BC effort Polium One was called out for basically ripping off the GameCube logo (by rotating it 90 degrees clockwise). Palleon's logo looks nearly identical to Polium One's logo.
Also, after the nonsense with Theranos, people should be very leery of another university-incubated start-up claiming miracles.
Amazing wisdom... God Endowment
9:32 Interesting., I've always been able to detect the true character behind every face., this is why if I have to pretend at being human, I choose solitude and celibacy.🤣
Carbo instead of Sugar
Sugar,makes,ur platets sticky ...and virus or bacteria knows this.,My sister is a micobiologist
A miracle? Really?
8:51 there’s nothing heterosexual about this
Fungus
Giving M Pffifer an ugly old look was a cheap trick., everyone will get old and ugly
O grow up and get over yourself. What stupid childish response.
@Taylor C. Powell Calm down honey.
What types of cancer would it be implemented upon?