Basically:you are shunting blood from an area (alveoli) of low oxygenation to an area of higher oxygenation, so that you increase gas exchange in an attempt to maintain good oxygen saturation. More simply: Take blood from where there is no oxygen to an area where the blood can pick up more oxygen and give it to the rest of the body! More Simpatico:Move Blood from where there is no O2 to an O2 rich area!
Found it! See a paper by Wang et al (2012). In a nutshell: Hypoxia is thought to inhibit K+ channels of capillary membranes to cause depolarisation. This depolarisation is propagated via connexin-40 to arteriole membranes. There, voltage-dependent calcium channels open and caclium influx results leading to the constriction of arteriole smooth muscle.
Great explanation, used this to compare/contrast with response to hepatopulmonary syndrome vasodilation... Two reactions happening in the same lung. -Brad RRT
Basically:you are shunting blood from an area (alveoli) of low oxygenation to an area of higher oxygenation, so that you increase gas exchange in an attempt to maintain good oxygen saturation.
More simply: Take blood from where there is no oxygen to an area where the blood can pick up more oxygen and give it to the rest of the body!
More Simpatico:Move Blood from where there is no O2 to an O2 rich area!
What is both lungs were oxygen deficit ? Will HPV still happen? If yes, where will it shunt the blood to ?
Thank you for this straight to the point explanation!
@@florence6654
it just like if both kidneys death = failure of kidneys....
so what happen to the lung lack of blood flow and oxygen? Ischemia?
Excellent explanation and very relaxing, comforting voice.
Found it! See a paper by Wang et al (2012). In a nutshell: Hypoxia is thought to inhibit K+ channels of capillary membranes to cause depolarisation. This depolarisation is propagated via connexin-40 to arteriole membranes. There, voltage-dependent calcium channels open and caclium influx results leading to the constriction of arteriole smooth muscle.
thank you sooo much. you just save my grade.
Explained it so well, great job!
What a great explanation, THANKS A LOT!!
and it is chronically leads to right side heart failure . Because of the hypertension of pulmonary vessels and cor pulmonale develops
Only lungs, in other tissues low PO2 induce vasodilation.
What is the treatment for hypoxic vasoconstriction.?
Great video! Thanks
Superb!
Thank you very much
This is perfect!!
Thank you 🙏
Thankyou ❤️ very well explained.
This is the best explination i heard about this topic 👏 ❤
Great explanation, used this to compare/contrast with response to hepatopulmonary syndrome vasodilation... Two reactions happening in the same lung.
-Brad RRT
Man, you just rulled it! Thanks a lot!!
so can I use health and medicine videos to prepare fro MCAT ??
perfect thanks
you are the best, i love you keep going
Awesome
Does this only happens for arterioles in the lungs or in other organs as well?
Only the lungs
good expline :)
What is the signal? In exams we need to name stuff like that!
Great video, but I could not help thinking of Jack Sparrow and his "peanut,mine!" moments in the 3rd pirate movie :)
Why not vasodialatation occurs as in systemic hypoxia vasodialatation occurs?
How fast the hypoxic pulmonary vasoconstriction occurs after an acute bronchial obstruction?
Depending on what you read when PaO2 falls below 70