Adderall And Modafinil Vs. Real Nootropics
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- เผยแพร่เมื่อ 16 ม.ค. 2023
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Genuinely hilarious that Derek is both the biggest and most learned person in the room.
Agreed. It’s funny as he’s very clearly the smartest in the room when compared to the two.
@@michaelm3584 why?
people have all sorts of differences, how is that hilarious?
@@TheErikk69 People stereotype and if someones big and muscular they assume he’s either dumb or not that smart, which i wouldn’t agree with lol
@@Evan-pt8nr right right, I getcha
They’re shaking their head acting like they know what Delts is saying 😂😂
Bro i am a pharmacy student and even i have to stop and think "......oh shit we did study that!!", Derek's just on another level
Even if you know nothing about these drugs the point he was making was really straightforward
Someone give this man a honorary medical degree.
I am medical student and he knows more about pharmacology then 50% of my class so I agree
give us all a break.
@@aldocompagnoni5851 what do you mean? Just because you don't understand what he is saying don't think it's not true! Do research and if you can understand just a bit, you see that he is correct in what's said
@@Adamman-ii8kj he os a chemical engineer
hes wrong though
The best nootropic is to get off social media
Dianosed with ADHD since 8, I’ve been taking adderall XR ever since so much that my brain can not produce dopamine on its own anymore and expects my body to take the adderall pill every day. Almost one year off and slowly improving naturally.
Stay at it 🤴
You can do it! Aaron doughty has ADHD and said instead of looking at it as a bad thing look at like a super power. You have more energy than user just have to harness it day by day. But of course easier said than done.
I'm in your boat I've been 2 years off and recently started taking it again as needed and no more then 10mg a day. Before I was prescribed 30-60mg XR's. More so think of your day ahead and think where the ADHD is more beneficial then the Normal Addy brain.
@@johnathanheatherman6438 I feel you there. I used to take 60mgs of XR and I've been off since 2014 and since I've gotten used to not taking it I feel like I have superpowers
Glad to hear it my friend. I was in the same boat around 12 years and xr was kinda traumatizing, IR worked better personally. Best of luck
My man was nodding his head like he understood what Derek was saying. Lmfao😂
Everything he said was a very basic, surface level understanding of nootropics, and physiological responses to moda and Adderall. Literally nothing insane.
@@JoshBruin77you say this as if the average person has a basic understanding of what the fuck you just said
@@kcroz1104 bro, wtf. I'll say it louder for those in the back: If you took a very basic intro to human bio 101 in college, or are a member of his channel, then you probably know this stuff. The average American needs to catch up, apparently.
Why is this the 3rd time I've read someone comment this? You guys just regurgitate comments?
The thumbnail for this short made me think Derek was doing stand up or something 💀
Lmao I thought the same but it was such a random thought that I never imagined someone else would post this
I love how this comes up as soon as I start debating whether I have adhd and have been looking into nootropics.
Don’t
Adult ADHD, in my research/experience, can be differentiated best by the executive dysfunction and working memory issues. More strongly inattentive and hard to diagnose if long-term depression/anxiety. If you don't show dopamine deficiency you don't have it.
It's extremely legit in adults, and often overlooked because it's so over and misdiagnosed in low-IQ kids who have no impulse control.
Imagine Derek and Andrew huberman talk about actually nootropics or neuron benefiting substance and protocols!
I need that conversation badly!!!!
@@highvalue1195 same,
But what's your best guess as to what they would talk about?
They’ve literally done a podcast together 😂
@@ABCDEF-br6it I think I meant it being more centered towards those topics
@@marz.6102 “I think I meant it” do you not have control of your own mind?
Great to see my man Derek looking dapper and breaking down the these compounds and their unique properties and potential benefits and side effects
There's little information on how modafinil works - it is a DRI, but it's an exceptionally weak one. There's a 7% increase in extracellular dopamine (amphetamines can be up to 600%, for reference). Labeling modafinil as a DRI and dismissing it because it ever so slightly increases dopamine is incredibly reductive and while factual, untruthful.
For even more context, food rewards increase extracellular dopamine by over 35% - so if modafinil is a DRI, so is food. PMID: 3362036, DOI: 10.1523/JNEUROSCI.4759-10.2011, DOI: 10.3389/fncir.2013.00152
As someone who’s taken both. Modafinil does not increase dopamine to any noticeable extent. It’s a better stimulant than caffeine, and it’s less dopaminergic than peanut butter 😂
@@SebastianCamposTech bro actually bought the sauce 😬
Someone had to say it. He says dopamine reuptake inhibition is its main mechanism of action which is not true at at.
It’s a eugeroic aka wakefulness promoting agent.
I’ve taken plenty of both and trust me, modafinils effect on dopamine is weak if even noticeable.
Although it does come with other concerns for me so I don’t use more than once per week.
He is just shitting on things which are popular and pushing his own products.
I used alpha GPC and I guess my choline levels were already good because it made me feel *weird* almost like a very minor stimulant rush, including a very minor stimulant-like crash right at about the 3-4 hour mark when it's starting to clear out of the body. Very strange experience for a simple neurotransmitter
So many factors can play into your experience. For me, I realized GPC worked better when my diet was sufficient and plentiful and I slept good. The sleep is important so you don't feel tweaked/burnt out from the supplement.
It works really well for me now. I take it 20 mins before my morning coffee and it works longer than before. Around 6-8 hrs as it should given the half life
Give us some new videos! Been a month since I've seen anything longer than 60 seconds--- miss good content, you are one of the few that still has it.
Love the way he broke this down, doesn't sugar coat adderall
Broke what down? If you mean the subject of nootropics, sure...if you mean the drugs Adderall or modafonil. No, he did not do justice for these drugs. THESE ARE FOR ADHD and prescribed by a qualified professional (provider) after diagnosis. We are trying to balance/ improve a condition not produce "limitless" effects
@@alec4547why was Adderall brought up in this conversation?
@@alec4547 World of the blind
The problem is he is completely wrong about adderall
@@alec4547 its also worth noteing, literally no drug makes you "smarter" doesent exist and never will.
All adderall and other amphetamines do is allow you to focus on study better, and retain that information better by building stronger pathways in the brain.
Theres no magic drug that makes you smart, just stuff that makes learning easier
Moda is extremely cognitive enhancing in my experience far more than alpha gpc but that’s good as well.
Good to see D is blowing up...he's been putting out great content for awhile
Derek, could You make a video about AG1 by athletic greens please
Without Adderall I would not be anywhere near the path I am today. The things Ive set my mind to that I was too depressed to even consider otherwise, and the healthy habits I've formed over years as a consequence. I also don't abuse it (often) I take about 5mg/day mon-fri. Used to take a lot more in my early 20's.
same, i couldent reliably get anywhere without the stuff, with it always on time
its not a cure sure, but does it make things better? without a question
Never met an adderall user in my life that didn’t eventually become dependent
Get off that shit bro. I was on it for 6 years, said the same thing. And ended up abusing it. Adderall is straight up meth.
Bro the only reason i got through my engineering was because of modafinil. God bless that thing lol
Did you come off it when you were done? Was it an issue?
@@thatstheguy07 It was not addictive at all. I just took it during exam time. It kept me awake and i only had to read through once to understand everything and your concentration gets boosted like crazy. Other than that, it had no effects that makes you wanna try it just for fun.
@@sin9324 I see
@@thatstheguy07 yeah dont listen to this guy about modafinil hes dead wrong lmfao
@@treeskers lol
Nice Derek , love listening to you bro .
I've taken adderall plenty of times, IR & ER, and I've been on both Provigil and Nuvigil for over a decade. My job demands it, being on call 24/7/365 and never going to sleep or work at the same time twice. Adderall initially, works wayyyyyy better. Much stronger, but after 4, 5, 6 days of it, you don't get that same "hit". I find Provigil and Nuvigil to be much better in that area, meaning I can take it daily for awhile and I still get results. Also, Adderall, being an amphetamine, is physically addicting and you will notice withdrawal if you take it for awhile and stop. Never felt any withdrawal from stopping Provigil or Nuvigil.
@@dylancounte1448, I work in transportation and have been diagnosed with shift work disorder. I have / had prescriptions for Adderall, Provigil, and Nuvigil. I have no set hours, on call 24/7 all year. I work an average of 270 hours a month, not counting all the time in the hotels. It's a brutal lifestyle, but necessary.
@@dylancounte1448, yea. It's brutal. I work for the Railroad. It's gotten so much worse, especially the last 5 years. Management just wants to run you to the bone. The money is good, but you work for it. I tell a few people who ask how much I make and they go "OMG I'd gladly do anything for that kind of money". But they have absolutely no freaking clue. New hires say the same exact thing, and yet the 5 year retention rate is less than 30%. So many quit within the first 2 - 3 years. No time off, work every weekend, holiday, always gone from family, miss all your childrens games, birthdays, etc.... For most, by year 2 or 3, the same new hires that said "OMG. This is great", now quit and say "you can't pay me enough to work this job'. We don't get paid because we work especially hard. We get paid for the miserable lifestyle and the toll it takes on your health. The average retiree collects 13 month's of Railroad Retirement than dies, and we can retire at 60, so the shitty sleep, gas station food, takes a toll.
@@Drewg351so what’s your point
@@dearjuanThere's no point just read, think, don't write anything and keep scrolling.
Aderrall is a scary drug, so is alcohol. Coming from someone brung up in a household where those were abused badly
I wouldn’t say that in general it is but when abused it’s a whole other animal definitely something to avoid going ham on
@@deepfrieddan3519 adderall is a scary drug people with adhd it makes them slow and not act themselves and people without it it makes them speed and act like there in meth so really there pretty bad downside to it’s use period but I mean whatever you believe man
@@davidmerritt4091 I have adhd and have been prescribed it I’m speaking from experience. Anything I say do take it with a grain of salt bc I’m not a dr but I will say micro dosing a weekly dose rather than eating up your prescribed dose makes a huge difference in mitigating side effects, and the reason Adderall makes none adhd people act like they’re on meth is bc they’re in a class of drugs called amphetamines.
@@deepfrieddan3519 you have low dopamine adhd?
@@Dedicated_.1 yes before going on script I was low on endogenous dopamine
Is PQQ a safe nootropic for ADHD?
Man for a guy who’s expertise is marketing , he sure plays a great neurologist/nutrionist
Jordan Peterson was so full of it, when he said Derek’s primary skill is marketing. But what else can you expect from a doctor who gifted a nazi flag from 4chan to his brother.
Dang Derek! Big muscles and smarts
@MPMD- Just got diagnosed with hypertrophic cardiomyopathy. I am 52 years old. Wondered what your thoughts on TRT, helping people with active heart disease. I have read mixed reports. Thanks man.
Consult your physician bro please please please. You’re older and wiser than me but I’m just offering my two cents be careful taking advice from fitness influencers we’re talking about your heart man, any fuccups or if anything goes left… it’s lights out forever man. Take care.
@@jibril2473 I am obviously consulting my cardiologist. But Derek is an expert on the subject. Any and all information is beneficial. I appreciate your concern.👊
@@truenorth2653 im no doctor or derek but TRT in older individuals has shown great improvements in QoL even without heart disease so I could imagine the extra testosterone could help your body maintain strength and function, again I don’t know if trt could negatively impact you with your disease
@@cameronwolfe Thanks man. The studies I have found state exactly that. While exogenous abuse of testosterone or PEDs is a cause of heart failure, Replacement doses may be beneficial to maintaining a healthy lifestyle. Will find out more next week. Thanks guys.
Endocrine society guidelines and cardiologists alike don’t recommend any form of testosterone if you have a cardiac pathology. Unfortunately if you didn’t have HCOM, I would say go the TRT route but bad heart mixed with exogenous testosterone is a cocktail for hypertension, a CVA, blockage, any of those sort of problems. Just stay off and stay safe brotha
Alpha gpc gives me sleep paralysis and super vivid nightmares. I was using alpha gpc in 2015 before it got hyped. I was scared of the dark for like 6 months after I quit using that shit
Do bravermans personality test and come back with results
Sounds dope just ordered some
@@XxXnonameAsDXxX lol fuck no it isn't. I couldn't move my body but I could hear thousands of demons screaming. Most terrifying experiences of my entire life. It worked great for studying and paying attention in class though. Just make sure you cycle off cuz i took it for weeks straight. Maybe that's why it messed me up. If i could do it all over again, I'd do 1 week on 1 week off. And don't take it with ALCAR, cdp choline, or Huperzine A, etc.
@@XxXnonameAsDXxX Still to this day, if I take a acetylcholine precursor supplement I will get guaranteed sleep paralysis that night.
Hey Derek….I’ve been hesitant on trying Adderall and one of my friends suggested I try Subtracterall instead….. do you know anything about this?
This is more of the stuff I like to hear, maybe go over some natural herbs people take for all sorts of reasons and break down nootropics and the actual biological effects they have. Keep trucking Derrick do your thing
Amphetamines are neurotoxic and Aderal is a combination of 2 amphetamines, but four amphetamine salts. AlphaGPC is a true nootropic, but it's most often used together with racetams like piracetam, aniracetam, oxiracetam, pramiracetam or phenylpiracetam.
Adderall is only neurotoxic above 20mg.
You impressed me brother. You're the only guy I've ever told that too. I've been in bodybuilding for 30 years. I'm a little older than you are. And you're the only one that knows stuff as well as me or better that I've ever ran into.
“And it does some other stuff” lmao
Derek has come so far
Modafinil has been proven to increase memory recall in studies
I have looked far and wide and could not find conclusive evidence about moda and its derivatives hindering brain plasticity in the long term but I guess we fuck around and find out right?
Proven is a strong word mate. Remember to reserve judgement based on singular studies and wait for more systematic reviews of the literature. There is some evidence to suggest that amphetamines and methylphenidate (ritalin) can improve working memory in individuals with ADHD.
@@mathiaskovendy7292 all I'm trying to get across is modafinil is much safer alternative. A lot of my friends who took amphetamines then got hooked on on meth or coke. Amphetamines are dangerous
@@lt2cool4u I agree mate. Stimulants like amphetamines should only be used under supervision and with caution
@@lt2cool4u well using any controlled substance without an actual medical necessity will lead to abuse. I've been taking Ritalin for about two years. Went off a few weeks ago. And I've been back to my old adhd habits but no negative effects.
What brand IEMs you using? 👀
What Jacket is he wearing?
I take lions mane, korean red ginseng and turmeric for my adhd. It’s not strong like adderall, obviously, but it’s smooth and holistic.
I did a study for Pepsi on Citicolene to see if it affected brain function in any way and they’re currently in the works of publishing the research. It was a double blind so idk if it works or not but it’ll be interesting to see if it did
Link us to the study brah
I've heard (meaning I stumbled on a soundbite in a podcast) that ketamine actually regrows gray matter. I have no idea if this is true but I'm definitely going to look into it.
Im a psychiatrist doing research in psychopharmacology. Derek is partially right.
What's he wrong about
@@alexanderwindh4830 adderall, its not "Borrowing from later for now" thats just not how that works
He knows his stuff 👌🏿👌🏿
Cerebrolysin is the best nootropic I've tryed. It cured my 6 year depression
Please, tell us more about your experience with this!
@@abcbellido its the best supplement ive tryed and ive been through a lot
Psychotropic vs nootropic
The funniest thing about all of this is if anybody knows Derek at all then they know he was absolutely💯 stacked on some enhancers during the making of this video. Gotta take adderal with alpha gpc to confuse the body.😂
As someone prescribed pure dextroamphetamine, I agree that stimulants aren't *real* nootropics and don't help noetically. That said though, various psychedelics (especially psilocybin) can be and are incredibly powerful nootropics. Psilocybin is like straight up brain food and probably the most powerful nootropic in existence.
Okay I need to know. Derek do you use chewing tobacco?
Alpha GPC increases stroke risk tho.. choose your nootropics wisely.
Increased TMAO. One study. Dependent on gut microbiome. Get tested.
@@absbi0000 Not really.. search harder
So what’s the downsides or upsides to choline. Never heard it
lmao. obviously you don't eat your damn liver
Potentially attenuates bro....like Essentially
what are those ear phones, need them
Where tf is Derek? Last month he put out 5 videos and now hes just not posted in over a month?
I wish Derek knew what he was talking about sheesh… listen to him stumbling on his words pfft. JKJK, love Derek, love his channel, he’s the f*cking man!
You can't just add some, you got to Add 'er all!
Modafinil isnt a amphet at all?
Slight correction, adderall is not neuroprotective, but its not neurotoxic either, the idea that its "borrowing from later for now" is oversimplifying and assumeing the user is takeing poor care of themselves
methamphetamine though prescribed as desoxyn in the US has been shown in therapeutic dosages to not only be neuro protective but also encourage neurogenesis
for reference, average therapeutic dosage being for most adults 5 to 15 MG twice a day
Very few people are ahead of what the pharmaceutical industry has propagated about learning and memory. Derek is one of the few who understands the mechanisms which are most likely implicated in learning and memory, against what we’ve been “taught” to believe.
Well, thats rough
Did he say Adderall will make me stupid in the long term? Do I need to stop taking it?!?!
Been on modafinil non stop for 4-5 years every day. It’s pretty harmless from what I can tell so far
I’m a 39 female recently diagnosed with ADD and on Adderall. Are you saying it’s gonna affect my brain in a negative way long term? Ty
Stims like Addy taken at therapeutic (rather than recreational) doses are habit forming but otherwise relatively safe. In people with ad(h)d they affect the production and uptake of neurotransmitters in a manner that makes it possible for ADHD brains to function more like normal people's.
TLDR: It's not going to massacre your braincells or anything. Just don't abuse it. Take the minimum you need to fix your problem. Be aware that taking stims for long and suddenly stopping will cause withdrawals. Good luck and godspeed
Please don't listen to randoms on the internet when it comes to serious stuff like this, your doctors and pharmacists spent way more years studying these drugs.
@Tyler Pharmaceutical companies have no bearing on the diagnosis of any disease. There's strict separation between the pharmaceutical and medical profession and loads of regulations prohibiting these kinds of deals.
There are some legal paths pharmaceutical companies can take to influence doctors but they're too indirect to work like that.
Of course it's good to be skeptical and there's always the possibility of secret illegal deals but you gotta be realistic. Would a huge pharma company that's going to make money no matter what really risk that just to get a couple more customers from each clinic? It's not like sick people are in short supply.
Evidence in ADHD shows not only does it not cause permanent damage, it may help repair endogenous production. Basically, IMO, only people it may fuck up are kids and those misdiagnosed - if you start it after your brain is fully developed you're more than likely all good.
I just want to be able to study dammit.
YO i could recommend you where I got my pharmaceuticals from he got all kinda psychedelics can also guide you through if you're a newbie 😊
ARABICASTOREZ,👈👈
He on telegram or Instagram _-
Please don't listen to this clown, go see a psychiatrist. It could be chronic depression , ADHD , SCT , Aspergers syndrome, all of which can be very subtle, but the hard times add up over time and give you this sense of demotivation. They will run a few tests on you, and MRIs are usually a good indicative of neuro-divergence, that in turn prevents you from studying. After that you'll have to take a few tests to try and narrow down the search and then finally get a diagnosis. It can be a lengthy process but mental health should always everyone's be the #1 priority. Good luck!
What podcast is this?
More plates more dates
In the description....
modafinil just feels like when you take big dose of caffeine for the first time
Hmm kinda, not the same jittery heart racing effects tho
What’s your take on lions mane?
wtf i’m gonna do in long term if i can’t figure out my shit in short term
Wow listen to this doctor talk it's incredible 😂😂😂😂
You would supplement with choline?? Seems irresponsible given the metabolism of choline into TMAO
Phenibut is a popular one
Where is the full video
Someone said it’s the tmg podcast
Huperzine A is the king 🙌
Shilajit "conquerer of mountains and the destroyer of weakness" I've been taking it for years and I've never been more focused. It's a 400 million year old decomposed rainforest that oozes out of the Himalayan mountains. The Hindu called it shiva's blood. And the people in the Himalayan mountains live to be about 120-140 years old...and they take this stuff everyday!
Hoe much you pay?
Usually expensive
Post link to what u take?
@@coled1218 i also buy it by the pound on ebay. About $60 a pound on ebay or 100 for 2.2 pounds.
@@Joes7179 thanks for the response 👍
How long does a pound last?
@@coled1218 that's a good question. I take a medical dose because I have autoimmune issues. Which is about 6 pea size pieces twice a day. The pound is hard as a rock. And the stuff on amazon is a resin. I mix the resin in my coffee and I take the rocks like pills followed by a 20oz glass of distilled or spring water. Fulvic acid in shilajit doesn't mix well with chlorine so do not use tap water. But my girl and I both take it. And I noticed after 1 week of her taking it she was waking up in a good mood for the first time ever...
@@coled1218 I can even break it down how it works. Shilajit is 60-70% fulvic acid. Fulvic acid is the final form of decomposing organic matter. Hence why pesticides, herbicides and germicides are horrible for our crops. Because they don't let the fungus and mold grow and break down the organic material. And then the dirt doesn't make any of these good acids that we need to transport minerals and nutrients into our body. So we can add minerals out the ass to the soil and they have no way of making it into our body. And if they do make it into our body through supplements we have no way of absorbing these supplements without humic, humus and fulvic acids. Fulvic acid is a micro nanoparticle that can penetrate any cell in the body. It can carry 70 times it's molecular weight into a cell and puts the nutrients where it needs to go. Without fulvic acid we are most likely mineral deficient.
Where can I watch the full interview?
Adderall, vyvanse, ritalin, Valium and other psych are super accessible from this specialist I cop from very reliable source who ship’s discreetly can also guide you through if you're a newbie
@ JUMASTRIP
JUMASTRIP
ON TELEGRAM OR INSTAGRAM
ashwagandha is a good one
Noel looking lost lol
Modafinil is not an amphetamine
Bromantane caffein kratom phenibut combo
Modafinil is absolutely NOT an amphetamine period. This guy thinkers he knows more than he actually does. It’s not a combo amphetamine. It’s not even related nor has the same or similar chemical structure to amphetamines
Imo modafinil goes well with a 50/50 Dextro Levo, say evekeo, not so well with a 75/25 D L mix of adderall
Nicotine is number 1
@Tyler here’s a podcast from neurobiologist Andrew Huberman about the effects of nicotine on the brain. th-cam.com/video/uXs-zPc63kM/w-d-xo.html and here’s a study about the neuroprotective nature of nicotine and it’s ability to prevent Parkinson’s disease pubmed.ncbi.nlm.nih.gov/11772120/
@Tyler I don’t know if it’s the number one best drug but that wasn’t the question in the video, they asked what is the most popular nootropics and nicotine is definitely number 1
I want to know what he was looking at
My brain isn't even attempting to follow this... Alpha GPC and whatnot. I just think that Derek has a nice voice....
Link to full video please
Dude I’m looking for it as well, can not find it.
TMG podcast
I would love to take a pharmacology class someday. I only learned a bit through anatomy and physio. A little in bio and psych as well
Adderall, ritalin, Valium and other psych are super accessible from this specialist I cop from very reliable source who ship’s discreetly can also guide you through if you're a newbie
@ JUMASTRIP
JUMASTRIP
ON TELEGRAM OR INSTAGRAM
why worry about fitness, diet or weightlifting routines
I wonder how nootropics would affect/effect schizophrenia
New Tropics 🏝️
bro talk about adaptogens
2? More like 4 in adderal
Lol Derek saying there are two different amphetamines is misleading because it makes you think there are multiple homologous or analogous compounds but the only difference are the base salts. They also mess with the enantiomer ratio, I believe it's tweaked 3:1 d-l. Yes they have different dynamics and kinetics but they are one in the same. Y'all gotta read the literature cuz you will be vulnerable to misconceptions like this if ya dont
This guys like bill nye on sauce
Truth
Eggs are high in Colein aren’t they?
Choline… yes
Is he really floating through space or is that just a green screen? Either way it's crazy how great technology has gotten
Lol it's a green screen this is the TMG podcast and their set gimmick is that they are on an alien space ship
Why is this guy so smart? To my knowledge he didn't go to medical school or study medicine. How did he acquire all these knowledge?
Your lack of knowledge is the problem
What about L dopa?
Phenibut. Best fucking nootropic EVER. Until you stop taking it and go thru DTs and brain zaps..
Hope this is sarcastic. You're fucking yourself up badly long term if you're taking Phenibut regularly.
Gotta space it out man
@@khanager2814 you don't know your alive until you lay in bed for 3 or 4 days with insomnia and anxiety so bad your wish for death.
It was partially sarcasm mixed with alot of truth.
Should be reserved for occasional uses like a job interview or a big social event, or at the very most once a week
phen gives a weird sensation to your skin, both while on the tail end of the effects and then for the next day or so. even with small doses it can be rather uncomfortable
Babe wake up MPMD posted
Adderall has four amphetamine salts.
Love my racetams
Get me those drugs now please