Maybe I'm a little cynical, but it seems to me that the "experts" change their tune whenever they need a new product to hype, because the last one has stopped selling.
There is two sides to this, one is capitalist motives as you pointed out. The other would become any good scientist, going with the new evidence, accepting when you are wrong and being open and public about it.
That's why its critical to consider if the experts providing the study has any potential financial or social benefit to gain for reaching or underplaying certain conclusions.
Definitely agree about alcohol, my age is 61, and I am very active, I ride, run, and use weights, until recently I was a bad binge drinker for most of my life, and after these so-called great nights of drinking I could not remember anything about the night when I was drinking, nothing, so what was the point of drinking I asked my self, and I used to tell myself it was ok because I worked out, but my last session was pretty bad, it felt like my body was rejecting the alcohol, my body was telling me to stop so I said that's it no more, I now believe alcohol is a true poison to the body and the cause of many cancers, the feeling i have now in my body and mind is fantastic, especially my mood, but I find my drinking friends seem offended that I've stopped drinking, but no problem my life my health.
Looking at my family’s history it’s pretty obvious that bad lifestyle choices were the main reason for early death. For the most part those that made good choices lived well into their 80’s.
Resveratrol was found to reduce metabolic rate (coffee does the opposite) and last for a good 4-5 hours. This is something that can improve sleep, not something to be taken in the morning. Also, it's an additive to wine to help us metabolize alcohol better, but then someone released a study that showed it extends life, and then that was proven incorrect, and now the supplements reputation is ruined despite it still being useful.
The problem here is saying, the FDA that "it extends life". The chemical keeps you looking younger. The ruin the reputation by saying "Both the test and control groups died. Therefore, it doesn't extend life." I'm like, the animal taking the resveratrol clearly looks younger.
At last I find someone who thinks like me in terms of science. When you say that caloric restriction is not so important if you eat wholesome foods, I tend to go around those lines. Thank you!
So we should all strive to make the best out of our genetic potential. Also when we say "it's never too late", we should also emphasize that "it's never too early either", for those who love to procrastinate. Never procrastinate that change which will make you healthier.
Thomas, this makes so much sense. No one can get it right every time, but it's obvious where the data is going. We have control over our longevity. What a fabulous thing!!
My dad started smoking at 16 and chain smoked until 62. Stopped cold turkey and lived a healthy active life until Parkinson’s got him at 90. It’s never too late.
My great-uncle and his wife quit the cigs cold turkey in their 70’s. They continued their “happy hour” with drinks and nuts until her death at 88-89; he gave up the alcohol then but kept the nuts, and was still living (and even driving! Daytime) at 92. He carried a cane but didn’t really use it, and mentally was sharp as a tack. During ages 93-94, he had a series of small strokes, but once recovered still was able to stay in his senior living apartment. Only spent a little over a year in a nursing home before his death at 94. A great age for a gentleman of his era.
🎯 Key Takeaways for quick navigation: 00:58 *💡 Genetics play a smaller role in longevity (20-30%), while lifestyle factors have become increasingly significant.* 02:08 *🔄 Lifestyle changes, even later in life, significantly impact longevity, as seen with smoking cessation and increased physical activity.* 06:23 *❌ Resveratrol intake, despite previous hype, doesn't affect mortality or inflammation as expected.* 08:52 *🍷 Moderate alcohol consumption (1-2 drinks/day) doesn't increase lifespan, while higher consumption has a negative impact.* 10:01 *🍽️ Caloric restriction matters, especially with a healthy diet, but lifestyle choices outweigh solely focusing on calorie intake.* Made with HARPA AI
You need to do a little research my mother in the 1950s after each child she was told mothers milk is not good for kids. The formula was better and they had a new procedure instead of binding the woman to dry her breasts. They used x-ray. Thousands of women in the 50s and 60s ended up with cancer because of this scientifically new way of doing things these things need to be talked about just like with resvaratrol. The biggest mistake lately is where people have been told. Sugar was good for them and the fat was bad and this is why no one trusts science..
I have a couple of drinks a day I am 70 years old I workout eat mostly healthy and I never need to go to the doctor's. and I certainly don't look my age .
I know for me, that just seeing someone put in some kind of sincere effort to change their lives, had made a huge difference for them and how they interact with others, thus having a spillover affect which improves (for the most part) relationships with others. And I hope that my daughter isn't getting married every year. :D
Well... Sure, but the new studies are about turning off bad genes and turning on the good genes. Thats why low carb works so well. Theres a completely different set of genes expressed when you enforce support for fat based metabolism. Suddenly your body does things with fat it just didn't do before.
So, what you're saying is, my many years of downing my daily resveratrol with a bottle of red wine, while snacking on my 500 calorie a day diet, is NOT going to help me live to my target age of 150?
Genetics determines your weak links. The stress you put on the system determines if the weak links break. Stress = Not moving, bad diet, poor sleep, emotional stress, electromagnetic stress, chemical stress etc burdens the body has to deal with.
The only reality is how many years people live, my grandmother's family lived 100 years, they did not exercise, they received little sun, they ate everything including sugar and fried foods, some smoked and others drank liquor, zero vitamins; But if they went to bed early, eating small amounts, they worked hard, had a positive life, full of gratitude and God. I don't think people of this generation will live to be 100 years old.
The TH-cam fitness community won’t be happy until all the world’s scientists, medical professionals and academics agree that ultimately, the only thing that matters is biceps and deltoid training.
I stopped smoking and drinking during menopause and a little while later stopped ALL sugar and prossesed food gave myself a reset (my own version of the gerson diet) I absolutely believe if I hadn't I would have died There is a lot we can do to help ourselves i need more motivation for exercise though
Sometimes it literally is just good genes. Both my paternal and maternal sides of the family live to be in their late 80's and usually mid 90's. Only one Uncle on my fathers side ran 5 miles a day from the time he was in the service till his death living a very clean life and remaing thin/lanky. His siblings abused almost every substance know to man. All of them lived very self indulgent lifestyles until they dropped in their mid 90's.
If you have the genetic potential to live long, and if you stay away from drugs, alcohol and junk food you're bound to live to that maximum potential. If you include those things in your lifestyle, you'll be the one that doesn't live as long as your siblings. All my uncles are proof. The one that didn't smoke and rarely drink is still living whereas all of his brothers were dead in their early sixties. You might say coincidence but I've seen this more than several times.
It depends on one thing. What do you do with Jesus. Believing and Trusting in Him is the only way to heaven. It is real. Trust him today. Don’t reject Him my mate
Science gets things wrong?!?!? Yeah, I think The Science got a lot of stuff wrong in the last four years. But I won't mention exactly what they got wrong, but it rhymes with Lovid.
On the alcohol front Zoe Research and others have found the only real non negative alcohol approach is red wine limited to one glass 150ml - due to its high polyphenols and also its positive effect on gut microbes but red wine was about it (with maybe port wine next in lower amounts) but everything else was not advised. So you want a drink then red wine might be the only current safe option.
Does sunlight work through windows 😜 also my theory for long life is what you started off with, 1940s babies started off with human milk and alot of fasting as a kid, 1980s babies started off with human milk and kids ate cereal, 2020 kids now on crazy formula and everything is processed as a kid, and by 2060 all the 2020 kids are Gona be dropping like flies lol
Sunlight through glass can still burn if excessive exposure, but does not adequately impact/reset circadian rythym. Outdoor/direct exposure is necessary for that. 10 minutes within 2 hours after sunrise on a clear day, 20 minutes if cloudy.
Thanks for the info … i follow most of the longevity crowd but hadn’t heard about these … did i miss them or are they not being talked about in this way? Either way, good video!!
I thought Resveratrol helped when taking an NAD booster (NMN or NR)? Maybe that's been found not to be the case anymore. Dang... have to research again, but thank you! I'd rather know the truth!
I'm still taking it. I just turn 31. Look on my late 20s, and guys my age already have crèpe skin, and graying hair. And I take it with niacin. I started taking them like 5 years ago.
Mike-hr6jz is right. Mothers were discouraged from nursing their infants by the medical profession. My mother, coached and supported by her mother and grandmother, bucked the trend to breast-feed me (1950) and my brother (1954). Thank God!
How do we explain people who smoke, drink, and hardly ever sleep living over a hundred years in excellent health? .. There's actually a guy in Vietnam who chain smokes, has a diet of 90% rice wine and very little solid food, And he NEVER sleeps. He hasn't slept since 1972!
Did the study on resveratrol implement taking it on an empty stomach or with food? It's completely ineffective without food. It would be the equivalent of trying to absorb fat soluble vitamins/minerals by drinking water.
The key takeaways from Thomas DeLauer's discussion on "5 Things Longevity Scientists Changed Their Minds On" are: 1. **Reduced Role of Genetics**: Genetics are less influential in determining lifespan than previously thought, accounting for only about 20-30% of longevity. The emphasis has shifted towards lifestyle factors as more significant determinants of how long we live. 2. **Impact of Lifestyle Changes at Any Age**: It's never too late to adopt healthier lifestyle habits. Changes such as quitting smoking or starting to exercise, even later in life, can significantly improve longevity and reduce all-cause mortality. 3. **Importance of the Microbiome**: Emerging research highlights the critical role of the microbiome in health and longevity. Lifestyle changes that positively affect the microbiome can lead to significant health benefits, suggesting a dynamic interplay between our lifestyle choices and microbial health. 4. **Reevaluation of Resveratrol's Benefits**: Once touted for its anti-aging properties, resveratrol has been shown not to impact mortality or inflammation significantly. This challenges its status as a longevity supplement. 5. **Alcohol Consumption and Longevity**: Contrary to previous beliefs that moderate alcohol consumption could extend life, recent studies show that even moderate drinking does not improve lifespan and may have negative effects on longevity. 6. **Caloric Restriction and Diet Quality**: The benefits of caloric restriction on extending lifespan may depend on the quality of the diet. While caloric restriction can be beneficial when the diet is poor, a high-quality, whole-food diet may naturally regulate body needs without the necessity for deliberate caloric restriction.
We are making this much more complicated than we need to. We come from biology, so let’s embrace it. Eat the foods that developed our species, in the most natural and wholesome way possible. Be active in a similar way that our ancestors were, within reason. Try to find a balance between work and pleasure.
I don't think resveratrol adds yrs I don't think anyone should take any them for that but resveratrol can do a lot to help with your health span which should be of interest
Of course, the entire content surrounding genetics, doesn’t account for so many older people who treated themselves like crap their whole life, living well into their 80s and 90s. Happens all the time…..
20-30% is huge! Up to one third of the equation! That's massive. Sure, you've got some other stuff to work with and no doubt lifestyle is the majority or it... but 30% is gigantic. Don't kid yourselves.
Lifestyle choices in my opinion play a greater role than genetics and Alex Hormozi says a similar thing, as do most highly successful entrepreneurs. Fortunately the simple boring choices we make work the best.
so he's saying there's no advantage to fasting and to consume omega 6's and sugar isn't bad and ice baths are a waste of time and he's right bc he found one little study for these claims?
I don’t agree that lifestyle trumps genetics throughout a person’s life! I think when you are young, you have much more buffering capacity and lifestyle actually probably trumps genetics. But as that person gets older, I think that this ratio of lifestyle vs genetics changes and eventually when you are approaching your lifespan potential, genetics then becomes much more dominant than lifestyle. Overall, I just think that those two factors are dynamic throughout one’s lifetime!
Lifespan potential is NOT the same as longevity. Having good genetics can give you longer than average potential lifespan, but if you have horrible environmental/behaviour factors (eg. obese, inactive, high salt and fat processed foods. smoking and alcohol) then you can still end up with a lower longevity than average, despite 'great genes'. On the other hand, two people living 'perfect' fit, healthy lifestyles in the same environment can stilll have different lifespans -- often due to underlying genetic factors (eg. probability of some cancers, heart disease etc that 'run in families'). I think I have 'good genes' but my diet and exercise suck, so I am trying to address that. You can change your lifestyle, but can't change your genetic factors. So even if genes do matter a lot, they aren't something to focus on in terms of useful action to maximize your healthy lifespan.
You don't know what you're talking about regarding genetics and lifespan. The study you mentioned only deals with the average lifespan until about 90. After that, genetics play a gigantic part. Do your homework. It's 50% genetics to 105 and 75% after that. Stop spreading misinformation
Get my Free 1-Week Gut Health Protocol. No strings attached. Just good info: www.thomasdelauer.com/gut-health
Maybe I'm a little cynical, but it seems to me that the "experts" change their tune whenever they need a new product to hype, because the last one has stopped selling.
You nailed it !
There is two sides to this, one is capitalist motives as you pointed out. The other would become any good scientist, going with the new evidence, accepting when you are wrong and being open and public about it.
It’s called “following the researcher” go educate yourself 😂
Sometimes that product is just their next book or podcast that needs to have topics in it that others aren't already talking about
That's why its critical to consider if the experts providing the study has any potential financial or social benefit to gain for reaching or underplaying certain conclusions.
Definitely agree about alcohol, my age is 61, and I am very active, I ride, run, and use weights, until recently I was a bad binge drinker for most of my life, and after these so-called great nights of drinking I could not remember anything about the night when I was drinking, nothing, so what was the point of drinking I asked my self, and I used to tell myself it was ok because I worked out, but my last session was pretty bad, it felt like my body was rejecting the alcohol, my body was telling me to stop so I said that's it no more, I now believe alcohol is a true poison to the body and the cause of many cancers, the feeling i have now in my body and mind is fantastic, especially my mood, but I find my drinking friends seem offended that I've stopped drinking, but no problem my life my health.
Good on you. My smoking mates were like that, too, when I gave up... onwards & upwards!👍
Looking at my family’s history it’s pretty obvious that bad lifestyle choices were the main reason for early death. For the most part those that made good choices lived well into their 80’s.
Genetics load the gun LIFESTYLE pulls the trigger !!!!!!!
😂
Resveratrol was found to reduce metabolic rate (coffee does the opposite) and last for a good 4-5 hours. This is something that can improve sleep, not something to be taken in the morning.
Also, it's an additive to wine to help us metabolize alcohol better, but then someone released a study that showed it extends life, and then that was proven incorrect, and now the supplements reputation is ruined despite it still being useful.
The problem here is saying, the FDA that "it extends life".
The chemical keeps you looking younger.
The ruin the reputation by saying "Both the test and control groups died. Therefore, it doesn't extend life." I'm like, the animal taking the resveratrol clearly looks younger.
And yet, some "longevity experts" are still swearing that resveratrol is one of the best supplements you can take
Resveratrol isn't added to wine. Grapes naturally produce resveratrol. Depending on the processing method, there is as much in grape juice as in wine.
The resveratrol is right there in the grapes and grape juice. You don’t need wine to get it. Oh, even raisins!
At last I find someone who thinks like me in terms of science. When you say that caloric restriction is not so important if you eat wholesome foods, I tend to go around those lines. Thank you!
So we should all strive to make the best out of our genetic potential. Also when we say "it's never too late", we should also emphasize that "it's never too early either", for those who love to procrastinate. Never procrastinate that change which will make you healthier.
“It’s never too early to start…” is a great motto. Today is a beautiful day to start a healthy habit🙌🏻
Great point!👍
Thomas, this makes so much sense. No one can get it right every time, but it's obvious where the data is going. We have control over our longevity. What a fabulous thing!!
Don't care how long I live. I just want to feel amazing every second I'm still here. "Curse of the optimizer".
I don't usually comment on TH-cam videos, but I just wanted to say this is an awesome video. I loved all of this info. Great job Thomas!
TIME to focus on groups who are already healthy and what helps to do even better. Never heavy, never smoked, never had notable negative vices.
My dad started smoking at 16 and chain smoked until 62. Stopped cold turkey and lived a healthy active life until Parkinson’s got him at 90. It’s never too late.
Same, my dad started at 13 and didn’t quit until he was 60. He passed away at 87, and it wasn’t from cancer, it was Alzheimer’s.
My great-uncle and his wife quit the cigs cold turkey in their 70’s. They continued their “happy hour” with drinks and nuts until her death at 88-89; he gave up the alcohol then but kept the nuts, and was still living (and even driving! Daytime) at 92. He carried a cane but didn’t really use it, and mentally was sharp as a tack. During ages 93-94, he had a series of small strokes, but once recovered still was able to stay in his senior living apartment. Only spent a little over a year in a nursing home before his death at 94.
A great age for a gentleman of his era.
Good morning 🌄🌄 thanks for sharing...... From the gymnastics center, adult classes this morning 🎉😂😂🎉
you exercise with rubber bands or wooden sticks?
🎯 Key Takeaways for quick navigation:
00:58 *💡 Genetics play a smaller role in longevity (20-30%), while lifestyle factors have become increasingly significant.*
02:08 *🔄 Lifestyle changes, even later in life, significantly impact longevity, as seen with smoking cessation and increased physical activity.*
06:23 *❌ Resveratrol intake, despite previous hype, doesn't affect mortality or inflammation as expected.*
08:52 *🍷 Moderate alcohol consumption (1-2 drinks/day) doesn't increase lifespan, while higher consumption has a negative impact.*
10:01 *🍽️ Caloric restriction matters, especially with a healthy diet, but lifestyle choices outweigh solely focusing on calorie intake.*
Made with HARPA AI
It's already time stamped dude
ty
the last line was a wrong summary
THIS was a GREAT episode ! I LOVED the primer, and the findings are so spot on too. ty deLau ! Appreciate the nuance in the last takeaway *peace* !
Psssssssst - come back in, say, five years and guess what .....? [It's called science and science is ALWAYS a work in progress]
You need to do a little research my mother in the 1950s after each child she was told mothers milk is not good for kids. The formula was better and they had a new procedure instead of binding the woman to dry her breasts. They used x-ray. Thousands of women in the 50s and 60s ended up with cancer because of this scientifically new way of doing things these things need to be talked about just like with resvaratrol. The biggest mistake lately is where people have been told. Sugar was good for them and the fat was bad and this is why no one trusts science..
Maybe glass of wine wont extend your longevity but glass of good wine in good company after accomplished day will.
I have a couple of drinks a day I am 70 years old I workout eat mostly healthy and I never need to go to the doctor's. and I certainly don't look my age .
I know for me, that just seeing someone put in some kind of sincere effort to change their lives, had made a huge difference for them and how they interact with others, thus having a spillover affect which improves (for the most part) relationships with others. And I hope that my daughter isn't getting married every year. :D
The fact that science gets so much wrong is why scientists should stop being so arrogant & back off insisting people do certain things.
"No, you must listen to the 'experts'. Don't try to think for yourself. The science is settled!"
Genetics being 20-30% is a very significant. Not to be downplayed.
Well... Sure, but the new studies are about turning off bad genes and turning on the good genes. Thats why low carb works so well. Theres a completely different set of genes expressed when you enforce support for fat based metabolism. Suddenly your body does things with fat it just didn't do before.
Thanks Thomas. My fave video of yours.
So, what you're saying is, my many years of downing my daily resveratrol with a bottle of red wine, while snacking on my 500 calorie a day diet, is NOT going to help me live to my target age of 150?
Don’t worry, my alcoholic chain smoking grandfather lives till like 91. You’re good
I know you were joking but I think you would need to drink maybe hundreds of bottles of red wine per day to get a meaningful dose of resveratrol.
Genetics determines your weak links.
The stress you put on the system determines if the weak links break.
Stress = Not moving, bad diet, poor sleep, emotional stress, electromagnetic stress, chemical stress etc burdens the body has to deal with.
Bill Gates says chocolate covered m&m’s are really good for you. 😳
The only reality is how many years people live, my grandmother's family lived 100 years, they did not exercise, they received little sun, they ate everything including sugar and fried foods, some smoked and others drank liquor, zero vitamins; But if they went to bed early, eating small amounts, they worked hard, had a positive life, full of gratitude and God. I don't think people of this generation will live to be 100 years old.
So glad I quit alcohol 3 1/2 years ago
I quit just 5 days ago and am going to stick with it
@@martinepeters9891You won't regret it
The TH-cam fitness community won’t be happy until all the world’s scientists, medical professionals and academics agree that ultimately, the only thing that matters is biceps and deltoid training.
I stopped smoking and drinking during menopause and a little while later stopped ALL sugar and prossesed food gave myself a reset (my own version of the gerson diet)
I absolutely believe if I hadn't I would have died
There is a lot we can do to help ourselves i need more motivation for exercise though
It seems like my Heart Attack Diet is actually a healthy diet LOL!
Sometimes it literally is just good genes. Both my paternal and maternal sides of the family live to be in their late 80's and usually mid 90's. Only one Uncle on my fathers side ran 5 miles a day from the time he was in the service till his death living a very clean life and remaing thin/lanky. His siblings abused almost every substance know to man. All of them lived very self indulgent lifestyles until they dropped in their mid 90's.
Anecdotes are the best form of evidence
@@questionauthority-f6idon't be an asshole. He's 100% right about genetics. It decides everything about your life.
Nobody knows anything with certainty you can’t just arbitrarily change reality
I just got Seed and I hope it makes a difference.
If you have the genetic potential to live long, and if you stay away from drugs, alcohol and junk food you're bound to live to that maximum potential. If you include those things in your lifestyle, you'll be the one that doesn't live as long as your siblings. All my uncles are proof. The one that didn't smoke and rarely drink is still living whereas all of his brothers were dead in their early sixties. You might say coincidence but I've seen this more than several times.
We all live forever. Death is only a conduit to then eternal life. You will end up on one of two places.
No, YOU will end up in one of two places. I'm going to Alpha Centari with the Pleadians. All depends on your belief system.
It depends on one thing. What do you do with Jesus. Believing and Trusting in Him is the only way to heaven. It is real. Trust him today. Don’t reject Him my mate
Most people don't drink a glass of wine to live longer. There are benefits in one glass a day.
Science gets things wrong?!?!?
Yeah, I think The Science got a lot of stuff wrong in the last four years. But I won't mention exactly what they got wrong, but it rhymes with Lovid.
Movid? Bovid? Zovid? Hovid? Wow, I give up.
@end c It sure did. Agree.
Btw I like your YT name. Unfortunately I'm not "allowed" to post that other "c" word otherwise my comment disappears. Lol
On the alcohol front Zoe Research and others have found the only real non negative alcohol approach is red wine limited to one glass 150ml - due to its high polyphenols and also its positive effect on gut microbes but red wine was about it (with maybe port wine next in lower amounts) but everything else was not advised. So you want a drink then red wine might be the only current safe option.
Does sunlight work through windows 😜 also my theory for long life is what you started off with, 1940s babies started off with human milk and alot of fasting as a kid, 1980s babies started off with human milk and kids ate cereal, 2020 kids now on crazy formula and everything is processed as a kid, and by 2060 all the 2020 kids are Gona be dropping like flies lol
Light does work through house windows. My eyeglasses turn dark if I get close to a window (UV), and it feels hot (Infra Red).
Agreed!
Sunlight through glass can still burn if excessive exposure, but does not adequately impact/reset circadian rythym. Outdoor/direct exposure is necessary for that. 10 minutes within 2 hours after sunrise on a clear day, 20 minutes if cloudy.
Thanks for the info … i follow most of the longevity crowd but hadn’t heard about these … did i miss them or are they not being talked about in this way?
Either way, good video!!
I thought Resveratrol helped when taking an NAD booster (NMN or NR)? Maybe that's been found not to be the case anymore. Dang... have to research again, but thank you! I'd rather know the truth!
Yeah, I had 8 drinks in 2023. That makes me a drinker, technically.
When i took 1g of resveratrol a day my skin become amazing.
I'm still taking it. I just turn 31. Look on my late 20s, and guys my age already have crèpe skin, and graying hair. And I take it with niacin.
I started taking them like 5 years ago.
Mike-hr6jz is right. Mothers were discouraged from nursing their infants by the medical profession. My mother, coached and supported by her mother and grandmother, bucked the trend to breast-feed me (1950) and my brother (1954). Thank God!
Sinclair didn't get wrong he is a scammer a businessman. Intentionally , knowingly marketed his scams.
Ever notice its the byproducts of something else that all of a sudden get marketed as a healthy supplement? Crisco anyone?
Yes he comes across as an untrustworthy weaselpath.
Great 👍
Genetics account for the size of our lipids. A large LDL particle is a characteristic of someone who lives long.
Ok but I eat healthy, don't smoke, and exercise while my brother doesnt and he smokes yet he seems to be in better health than me
How do we explain people who smoke, drink, and hardly ever sleep living over a hundred years in excellent health? .. There's actually a guy in Vietnam who chain smokes, has a diet of 90% rice wine and very little solid food, And he NEVER sleeps. He hasn't slept since 1972!
Did the study on resveratrol implement taking it on an empty stomach or with food? It's completely ineffective without food. It would be the equivalent of trying to absorb fat soluble vitamins/minerals by drinking water.
Totally agree! In fact, Reservatrol needs to be takes with a fat (yogurt, cheese) to be assimilated properly
Doctors hate to adnit that genetics dont play much of a role and I guess some of their patients too 😂
The key takeaways from Thomas DeLauer's discussion on "5 Things Longevity Scientists Changed Their Minds On" are:
1. **Reduced Role of Genetics**: Genetics are less influential in determining lifespan than previously thought, accounting for only about 20-30% of longevity. The emphasis has shifted towards lifestyle factors as more significant determinants of how long we live.
2. **Impact of Lifestyle Changes at Any Age**: It's never too late to adopt healthier lifestyle habits. Changes such as quitting smoking or starting to exercise, even later in life, can significantly improve longevity and reduce all-cause mortality.
3. **Importance of the Microbiome**: Emerging research highlights the critical role of the microbiome in health and longevity. Lifestyle changes that positively affect the microbiome can lead to significant health benefits, suggesting a dynamic interplay between our lifestyle choices and microbial health.
4. **Reevaluation of Resveratrol's Benefits**: Once touted for its anti-aging properties, resveratrol has been shown not to impact mortality or inflammation significantly. This challenges its status as a longevity supplement.
5. **Alcohol Consumption and Longevity**: Contrary to previous beliefs that moderate alcohol consumption could extend life, recent studies show that even moderate drinking does not improve lifespan and may have negative effects on longevity.
6. **Caloric Restriction and Diet Quality**: The benefits of caloric restriction on extending lifespan may depend on the quality of the diet. While caloric restriction can be beneficial when the diet is poor, a high-quality, whole-food diet may naturally regulate body needs without the necessity for deliberate caloric restriction.
Resveratrol didnt help me but either did Nac among other supplements, we are all different, experiment on yourselves ❤
We are making this much more complicated than we need to. We come from biology, so let’s embrace it. Eat the foods that developed our species, in the most natural and wholesome way possible. Be active in a similar way that our ancestors were, within reason. Try to find a balance between work and pleasure.
I don't think resveratrol adds yrs I don't think anyone should take any them for that but resveratrol can do a lot to help with your health span which should be of interest
The UK is going down the toilet, but at least our politicians uphold the House of Commons debating rules ffs.
Based video.
Of course, the entire content surrounding genetics, doesn’t account for so many older people who treated themselves like crap their whole life, living well into their 80s and 90s. Happens all the time…..
“That’s the beauty of science”?….😳
For the algorithm. 💪
What about NMN?
If that 20% of genetics is in your favor, e.g. your people tend to live into their 90’s instead of 70’s, then 20% is not a small consideration.
What about many drinks on one day a week but none on others😂
20-30% is huge! Up to one third of the equation! That's massive. Sure, you've got some other stuff to work with and no doubt lifestyle is the majority or it... but 30% is gigantic. Don't kid yourselves.
I’m 33 and just ordered rosuvastatin… I want to keep my ApoB as low as possible for as long as possible
Because Peter Attia says so!
@@questionauthority-f6i yea and that’s the way the evidence seems to point, that ApoB is causal, not just a correlation
Longevity-wise (not considering other benefits), is fasting's longevity benefits just from caloric restriction?
Lifestyle choices in my opinion play a greater role than genetics and Alex Hormozi says a similar thing, as do most highly successful entrepreneurs. Fortunately the simple boring choices we make work the best.
so he's saying there's no advantage to fasting and to consume omega 6's and sugar isn't bad and ice baths are a waste of time and he's right bc he found one little study for these claims?
I don’t agree that lifestyle trumps genetics throughout a person’s life! I think when you are young, you have much more buffering capacity and lifestyle actually probably trumps genetics. But as that person gets older, I think that this ratio of lifestyle vs genetics changes and eventually when you are approaching your lifespan potential, genetics then becomes much more dominant than lifestyle. Overall, I just think that those two factors are dynamic throughout one’s lifetime!
David sinclair sells books though lol.
- we ha still NO IDEA how to slow down aging !
Yeaaah just like some of the "health experts" here on youtube started promoting carbs again..
... and some of it was INTENTIONALLY wrong. Don't kid yourself.
Smoking is just the worse.
"Changed their mind on." Like with cigarettes? Eyes on the now, not the horizon, people.
Another thing Science got wrong: Climate change is carbon dependent 🤣
Climate Change is cyclical. Ironic, how they ignore that. Antarctica was a rainforest island.
The "science" is SETTLED! 😂😂😂
@Ement Agree. Don't get me started.
@Ement And we all should believe a teenager who is being used as a puppet verses actual experts who disagree with the promo narrative.
hoax alert
They were wrong about botox & hair dye being longevity medicines???
$inclair is to supplements as pharma is to $cience.
David Sinclair or Peter Attia !!
Peter. 👍
Im up to a 5 gallon bucket of supplements per day recommended by social media infuencers. Surely Ill live forever.
David Sinclair is gonna die on that resveratrol hill, but i think he's considered a little squirrely, even among his longgevity peers.
Most of these "new" knowledge/wisdom were already common sense in ancient culture. 😂
What accounts for Warren Buffet?
He’s 93 years old with full mental acuity and claims to drink 5 Coca Colas per day plus be a regular at McDonald’s.
Lifespan potential is NOT the same as longevity. Having good genetics can give you longer than average potential lifespan, but if you have horrible environmental/behaviour factors (eg. obese, inactive, high salt and fat processed foods. smoking and alcohol) then you can still end up with a lower longevity than average, despite 'great genes'. On the other hand, two people living 'perfect' fit, healthy lifestyles in the same environment can stilll have different lifespans -- often due to underlying genetic factors (eg. probability of some cancers, heart disease etc that 'run in families').
I think I have 'good genes' but my diet and exercise suck, so I am trying to address that. You can change your lifestyle, but can't change your genetic factors. So even if genes do matter a lot, they aren't something to focus on in terms of useful action to maximize your healthy lifespan.
20 to 30% is not a modest amount
Tom - if ya wanna stay current, follow Dr Joel Wallach - he is years ahead of all this stuff.
It does after age 88
This Sinclair is a total bogus. He just preach whoever pays him
since i take resveratrol i dont get sick. thats all i know.
Genetics doesn't count? My mother never did any exercise, ate garbage, but didn't smoke and rarely drank. Was hugely overweight. Lived to 97.
You forgot NMN; the ultimate scam.
Well gee wilikers
How come no one seems to talk about getting and having enough sex is equally good for living longer 🤔🤔🤔
Are u wearing 2 watches??
( 1:44 ) Looks like it. Maybe one tells the time and the other is an exercise monitor.
The fuck is Reseveratriol?
A chemical found in wine, and synthesized from Japanese knotweed.
Its what Sinclair was hyping before he moved on to hyping nmn
You don't know what you're talking about regarding genetics and lifespan. The study you mentioned only deals with the average lifespan until about 90. After that, genetics play a gigantic part. Do your homework. It's 50% genetics to 105 and 75% after that. Stop spreading misinformation
Buzz killed…
would be cool if u could get david sinclair on!!! i know u probably see things differently but nevertheless friendly discourse has only gains!
We will see. Scientist Took the DNA from the oldest woman Alive (116) and want to study it if it genetic or not
I stopped watching exactly at 1min in lol