Overactivation of glutamate is a problem for certain autistic people like my daughter. Chris Masterjohn suggested glycine for sleep but some of the comments suggested that it could cause excitation which it definitely does with my daughter. Your presentation does mention glycine which was helpful for understanding this phenomenon.
I wish I found your channel sooner. I am currently taking my course to be a pmhnp in a master's program. Your video is so helpful. Please continue to make more.
As far as this video explains, magnesium is involved with NMDA receptor transmission as it blocks the channel at rest. This property leads to the concept of coincidence detection described in the video. I do not know that magnesium has roles beyond this in glutamate transmission. Let me know if that clarifies your question!
How would one go about slowing down glutamate or getting rid of it for benzodiazepine withdrawal? If a doctor abruptly stop the medication? Patient has acathisia severe terror anxiety mood disturbance no medications are working looking for natural way to slow down glutamate or to gabba.
Very good question and very clinical. Your question goes out of the scope of what I can confidently answer unfortunately. I would imagine cognitive behavioural therapies may be of help if no medications are taken.
Good question, I've never heard of agmatine before. By looking online I see that agmatine blocks NMDA receptor so I would say this supplement blocks the effects of glutamate. Did you find anything else on your end?
I did not cover acetylcholine alone but I did make videos that talk about all the relevant properties of acetylcholine and their receptors. Here they are: 1- Neuromuscular Junction Synapse Explained (nicotinic Acetylcholine Receptors) | Clip th-cam.com/video/memCXaPrkMQ/w-d-xo.html 2- Properties of Neurons In The Central Nervous System (Neurophysiology) | Full discussion (starting at 27:03) th-cam.com/video/bLhcKhYyxuw/w-d-xo.html In video 1 I explain how acetylcholine is used at the periphery and their respective ionotropic receptors. In video 2, I discuss their metabotropic receptors. Hope this helps! Let me know if you need anything else!
Good question, I have not done too much research on that topic but I would imagine that ketamine, having an influence on NMDA receptors, probably upregulates the sympathetic innervation of the heart coming from the central nervous system and thus increases blood pressure. Let me know if you find something else about this!!
Glutamate molecular structure is wrongly written
Wow, thank you for pointing that out! It should indeed have an OH group instead of the present NH2.
don't speak
Overactivation of glutamate is a problem for certain autistic people like my daughter. Chris Masterjohn suggested glycine for sleep but some of the comments suggested that it could cause excitation which it definitely does with my daughter. Your presentation does mention glycine which was helpful for understanding this phenomenon.
Hi, sorry to hear that your daughter has to go through this that must be very challenging! I am glad this video provided clarity for you!
Which transglutaminase has been analyzed ?
Glutamate
!!
Great video, I had not found something explained as easy as this one, thank you!
Thank you! I am glad it was helpful!
I wish I found your channel sooner. I am currently taking my course to be a pmhnp in a master's program. Your video is so helpful. Please continue to make more.
Thank you for the support! Good luck with your studies!
Very well done video! It's a huge help while tackling neuroscience and I look forward to watching your other videos
Thank you very much!
This was really really helpful! Thank you so much!
My pleasure!!
Can you explain more about the effects of magnesium on glutamate transmission? Or is there a video for that?
As far as this video explains, magnesium is involved with NMDA receptor transmission as it blocks the channel at rest. This property leads to the concept of coincidence detection described in the video. I do not know that magnesium has roles beyond this in glutamate transmission. Let me know if that clarifies your question!
How would one go about slowing down glutamate or getting rid of it for benzodiazepine withdrawal? If a doctor abruptly stop the medication? Patient has acathisia severe terror anxiety mood disturbance no medications are working looking for natural way to slow down glutamate or to gabba.
Very good question and very clinical. Your question goes out of the scope of what I can confidently answer unfortunately. I would imagine cognitive behavioural therapies may be of help if no medications are taken.
Have you made a video about glatamate and transglutaminase?
Hi, if you are referring to transglutaminase as the food additive I have not done a video on it!
What would the supplement agmatine due to glutamate I know it works NDMA receptor
Good question, I've never heard of agmatine before. By looking online I see that agmatine blocks NMDA receptor so I would say this supplement blocks the effects of glutamate. Did you find anything else on your end?
I cant find the acetylcholine video😢
I did not cover acetylcholine alone but I did make videos that talk about all the relevant properties of acetylcholine and their receptors. Here they are:
1- Neuromuscular Junction Synapse Explained (nicotinic Acetylcholine Receptors) | Clip
th-cam.com/video/memCXaPrkMQ/w-d-xo.html
2- Properties of Neurons In The Central Nervous System (Neurophysiology) | Full discussion (starting at 27:03)
th-cam.com/video/bLhcKhYyxuw/w-d-xo.html
In video 1 I explain how acetylcholine is used at the periphery and their respective ionotropic receptors. In video 2, I discuss their metabotropic receptors. Hope this helps! Let me know if you need anything else!
@@sciencewithtal thanks☺️
Very helpful. Thanks
Thank you!
Thank you for making this! I need you to tutor me.
Thank you for the support!
how you want it
Well then, anyone knows how ketamine increase blood pressure?
Good question, I have not done too much research on that topic but I would imagine that ketamine, having an influence on NMDA receptors, probably upregulates the sympathetic innervation of the heart coming from the central nervous system and thus increases blood pressure. Let me know if you find something else about this!!