Light-based therapy for Alzheimer's disease
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- เผยแพร่เมื่อ 6 ธ.ค. 2016
- *NOTE: This research has made major new strides since 2016. For a more up-to-date version, please see • GENUS: Research on sen... .
Researchers in Li-Huei Tsai's laboratory at the Picower Institute for Learning and Memory have shown that disrupted gamma waves in the brains of mice with Alzheimer’s disease can be corrected by a unique non-invasive technique using flickering light. (Learn more: news.mit.edu/2016/visual-stimu...)
Tsai Lab: tsailaboratory.mit.edu/
Watch more videos from MIT: th-cam.com/users/MITNewsOf...
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Video: Picower Institute for Learning and Memory
Animation: Sputnik Animation
Additional footage and music: Pond5 - วิทยาศาสตร์และเทคโนโลยี
5 years later, how are things going??? Any news???
Good work MIT and Picower Institute. Keep researching and fighting the good fight, you're appreciated by many including me.
Ok
Thanks so lsorry sorry to lto like lyou you guys guys had such great great care for us
Anyone organizing a week long Electronic/Dance Music festival, please set your disco lights to 40hz from now on.
sounds funny :) But yea, 40 flicker a second isn't the range people can perceive, or of course, have a disco with. On the other hand, your LCD screen typically flicker at 60-70Hz already.
Lmao
fantastic to hear that progress is being made in treating this heartbreaking and difficult disease
And with simple light-based treatments as well. Light is relatively speaking, quite inexpensive even to run for a few days.
40hz, but at what wavelength and irradiance? The animation shows what appears to be white light in use, with the rat subject. But, the effective range for hippocampal stimulation has been indicated to be near-infrared, between about 700nm and 880nm wavelength and with varying irradiance. Most effective of all is delivery via intranasal devices, which can shine NIR light up the nasal passage and into the hippocampus from beneath the brain, which is not reached by transcranial devices shining light through the thicker areas of the skull to treat other regions of the brain.
my mom worked with people with Alzheimer's and she said one of the patients was a young person and he was around 20
Thank you for your work. I hope you are well funded. I'd sit in front of blinking lights for 5 days to reverse or even prevent Alzheimer’s. Thanks again!
Find a Neurofeedback Professional/Clinic, and do some Alpha/Gamma sessions. I've been doing Neurofeedback for 8 years and my memory is razor sharp, almost to the point of remembering too much ...
can bring on migraines or seizures in some people, just FYI.
@@careym85 LOVE IT !! Thx for your very valuable input.
@@watchgoose Hello, can you please cite where you got this info., plzzz ????? I mean that is frightening, especially if recommending for an elderly person.
@@starrynight8007 He may be referring to the "flicker rate" of light which is how they get at people's minds via the TV, or the Pokemon episode "Dennō Senshi Porygon" in 1997 that sent 685 viewers to the hospital due to photosensitive epileptic seizures. If you want to learn more about how much light impacts our physiology, watch some videos of Dr Jack Kruse (NeuroSurgeon) - he explains in detail how the "light" we live in today is screwing up our brains. Peace~
Can 40 hz sound or light theropy be used when the subject is sieeping
Pls how can I get this device for my mother
Where can i find updates on this research?
so...how does it fix myelin sheath?
I am a producer at Mic.com and was wondering if we could use this video in a video we are making. Many thanks!
I wish this reaches to doctors and surgeons throughout the world. Sadly, it still hasn't . If I knew about this treatment earlier, my grandfather would have been sustained.
What isn’t included in this video is how this light was administered to the mice and for how much time daily. It may be in ways not achievable with humans.
@@YTLORI1 imagine if they strap the mice individually and force fed strobes 24/7...
A truly simple yet beautiful finding towards curing Alzheimer's!
Ur cute
So they going to use this to help Visual snow aswell
The AC power frequency in most countries is 50 or 60hz, which means that a lot of our existing lights already flicker at these frequencies.
What if we all just reduced our AC frequency to 40hz?
40 is special. The other hz ranges didn't elicit the same response.
@@digitalsamurai42 yes, you may have missed the final part of my post
Unfortunately delivering power at anything other than 60hz would interfere with a ton of appliances.
@@roidroid those with brain trauma can get instant headaches from flickering lights regardless of frequency. If they can see the flickering, they adapt to it rather than overriding it and this can not only cause instant headaches but also seizures.
You can produce a 40 hz stim using an AVE (audio-visual entrainment) device, or mind machine, rather easily. It comes with a pair of light glasses and headphones (I wonder if auditory stim of 40hz will help, too). Even a cheap AVE device ($100) will produce light stimulation from 1-42 hz. Most have a manual setting so you can dial up 40 hz, put the light glasses on and enjoy.
en.wikipedia.org/wiki/Mind_machine
Simply use binaural 40 Hz frequencies with head phones on you tube. The frequencies are safe. Be careful with flickering lights. Headaches, migraines and seizures can result.
Those with brain trauma can get instant headaches from flickering lights regardless of frequency. If they can see the flickering, they adapt to it rather than overriding it and this can not only cause instant headaches but also seizures.
Simply use binaural 40 Hz frequencies with head phones on you tube. The frequencies are safe. Be careful with flickering lights. Headaches, migraines and seizures can result.
I just wish research wasn't so slow
It's not age related and it is not a normal part of aging, AD is caused by many factors, Poor diet, diabetes, toxins in food like pesticides & mercury, toxins in water like fluoride and copper, toxins in the air, mould exposure, Lymes disease, vascular problems, lack of exercise, stress, high sugar intake, gluten, seed oils (very damaging), smoking (extremely damaging), hormone imbalance, trauma, lack of vitamins and minerals, poor gut health, poor dental hygiene, high blood pressure, statin use, poor sleep (we need 7-9 hours) to name some of the drivers, hope you ae starting to get the picture, we live in a toxic world so no wonder we are suffering. A good diet is the foundation to health so start there and build on the rest that may be an issue.
What spectrum of light? The same as in an ordinary light bulb? And if 40 hertz is optimal, does it have to be light at 40 hertz? Or would sound at 40 hertz work as well? And would sound be less or more effective than light? A rhythm at 40 hertz might be tolerable in the right kind of music. That flashing lght at that brightnss would be like a flickering fluorescent light on the verge of going out -- horrendous. And coud it trigger seizures in epileptics? For another alternative, is there a health-optimizing wattage of light that could be used instead to re-synchronize the microglia? This is a new term to me. What is the effect of being outdoors in the sunshine or on a cloudy day? How does that compare to the 40 hz light?
New research shows that near inferred at 1070 nm is the answer.
This is worth a try…watch this video & others like this. Mom can use headphones so each ear can hear. The 40Hz is crucial. Good luck!
A cure is not hard to create, it is simply not made yet(seen in large markets).
Yeah what about brain shrinkage?
were the mice genetically engineered?
40Hz? Maybe I should invest in a strobelight...
Is it a certain wavelength of light? Or is this something you could just make into an app or a video?
Tyler Matthew Harris i think so, they mentioned gamma
Mogale Tsebane I think they're referring to brainwaves. Gamma radiation is pretty terrible for you.
There is gamma light but it isn't visible. It's so strong that can cause genetic mutation/cancer.
Tyler Matthew Harris - Yeah the gamma referred to is the gamma brainwave function, which basically refers to the synchronized firing of neurons within our brain at different frequencies, or neural oscillation.
So they are using flashing light basically Tyler Matthew Harris... however I don't know if it is simply incandescent or what. But I would imagine that an app could be done, but perhaps with the camera flash?? They don't mention what sort of light they are using, but I would assume a strobe of some sort.
Really interesting and hope giving!
They're using LEDs. I've heard her discuss it in an interview with RadioLab.
This is interesting, promising and encouraging. We would hope that a lot of people can be helped by this. From another viewpoint, this is yet another example of the current medical approach of throwing a high-tech, probably very expensive (and therefore profitable) fix at a problem that can be prevented in many cases with a healthy, responsible lifestyle that avoids the known risk factors that predispose to the development of this condition.
This can be done with equipment costing $44.00. Most scientists working in this field want it to work for family & friends. Not to necessarily “clean up.”
Also, my mom has Alzheimer’s, but lives a very healthy vegetarian life. She’s travelled the world, is a painter, and so far is living to 90. I’m hoping 40 Hz rids her of plaque and reverses her Alzheimer’s. Who knows? It’s worth a try.
@@kathykitts5320 Also consider detoxing out neurotoxic aluminum by drinking Fiji water which is rich in the OSA form of silica, or look up the inexpensive Silicade recipe by PhD chemist Dennis Crouse.
but microglias are overactivated thus inflammatory.
just buy Vielight it's already on the market.
last stage
Food for thought: a similar beneficial effect can probably be achieved by having the LEDs flicker in peripheral vision as opposed to staring directly at it. The effectiveness may be reduced, but the treatment would be less prone to extreme boredom if it could be left on in a room while a human is free to do other things. If the brain is still stimulated at a beneficial frequency that seems key. From reading other comments, it's interesting to learn a DIY solution could be made for under $50 using the same LEDs used in the study ($9 on eBay) and an Arduino Uno to time the flash frequency.
... isn't the main problem telomeres as well?
But WOAHHHHH
that's soooooo coool!!!!!!!
Is it possible to harvest microgliya then?
Maybe we can create lenses that that do those flashes...
But as it's for elderly and lenses may not be the greatest idea...
:3
Sorry- I may be too hyped up! XD
What good would it do to harvest micrygliya?
the voice of the one who is documenting is not a good as one in the previous videos
Skull Crusher - bummer?
good clip
plz help me my mother is dementia
I believe at this stage, we have to help ourselves. There are a few articles on the internet showing us how to go about doing it at home. Apparently infrared saunas are also good. In the meantime I suggest you buy an infrared lamp for your mother. Strength to you.
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Since when does MIT use Google's text-to-speech?
Nice!
Does this work naturally, or does it requires genetically modified neurons that react to light? And does it work thru the eye?
It works naturally. Works either trough eye or by sound at 40hz for both light and sound.
mother is age 60y
Does this also improve cognitive performance?
Definitely!
Nice
No way
Sobugalam
WOW
Why not have human testing with this by having an app on your phone. put the phone in a VR headset and it's pre set to one hour then boom you're done. It's a therapy that can be done by anyone
because sales of the app wouldn't offset the money spent on clinical trials (aka proving it works) it has to make financial sense in addition to getting results. this is why we can't have nice things.
A Song About Alzheimer's: MadHero - Unforgettable
Background music is un-necessary, annoying and distracting.
Why 40Hz?
Tyler Matthew Harris That is a natural brain frequency.
+Len P I don't understand. Will you please explain?
Can't you simply google it and learn ton more information than a half assed layman term ?
+dragons google just turns up a whole bunch of pseudoscience sites. I was hoping Len P could make his answer a little less vague.
Tyler Matthew Harris Then go for a papers on neuroscience. If you can't differentiate pseudo from an empiricial science then you aren't reading science enough.
Here take this wiki acrticle: en.wikipedia.org/wiki/Gamma_wave
It says that there is a theory that 40 hz gamma wave creates a unity. Thus the disrupted neuronal waves caused by Alzheimer are controled through the flickering light, causing brain's gamma wave to be unified. Again, it's a theory which they are testing it on this mouse.
I'm not a neuro scientist but googling gamma waves took me 3 seconds.
sorry my ignorance, but this is not the first time that I see Russia as a part of Europe.... what's is going on?
I hope the military doesn’t hear about this treatment and decides on weaponizing it. Oops!
this is all highly circumstantial... Proof? Papers?
Googling for the masses: www.nature.com/articles/nature20587.epdf
💁🏻♂️ 👏🏾👏🏾👏🏾 Xxx
The Chandigarh Ayurved Centre provides various herbs that generally act on memory & treat all the symptoms related to Alzheimer’s patients. A kit named “Alzheimer’s Go Kit” is introduced specially for Alzheimer’s patients. This kit comprises five products Brahmi Vati, Brodley syrup, Nerve Up Tablet, Tagaradi churna, & Brain Relaxant churna.
The people with Alzheimer's are nutrient deficient, why don't we just get them to eat some healthy fats and vitamins and minerals instead? Their just needing some coconut oil, maybe some hemp and flax oil and a few extra vitamins and minerals and lots of nice butter and meat. Need to make sure they are not on some sort of fat uptake altering chemical medication too.
I'm still confused as to how someone can die of Alzheimer's? What do they forget to eat or something?
hootsmin oh man, please. You just listed the foods that cause Alzheimer's. the only healthy fats are whole nuts, seeds and avocados.
Saturated fats like butter, meat, dairy and eggs are the culprits, they clog our arteries, even the ones in our brain and they form the plaques that interfere with our brain.
The only diet scientifically proven that prevents chronic diseases like cancer, heart disease, diabetes, Alzheimer's is a whole food plant based diet, no oils, no sugars, no refined and processed products.
Just vegetables, fruits, whole grains, legumes, seeds, nuts, mushrooms.
@@PatrykKarter WRONG - COCONUT OIL DOES NOT REQUIRE INSULIN, like all the other LONG-CHAIN Plant foods You just listed.
INSULIN causes INFLAMMATION, hence affecting the "clogging" action you described.
=== Plz read a book on Medium-chain fatty acids.
That's funny... I remember the CDC banned the import and sale of a really effective Alzheimer's treatment drug.
which one is that, pray tell.
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One big commercial
for a medical treatment probably a decade away? Or for the awesomeness that is MIT
there is to many old persons now (to many humans basicly)
Alzheimers struggles are diminishing, thanks to igrotum. Witnessing improvements in cognitive abilities and mental clarity.