Me about sleep at 12AM believing that there are only four blood types YT notification: “There are millions of blood types” Me: *_”I don’t need sleep, I need answers!”_*
Évariste Galois If you are really interested there’s a class named blood bank. It’s hard, yet it teaches these different variations of blood types , Rh itself has many different variations , Example: DEc/cE DEC/ce Dce/ce ... etc There upon many different antibodies/ antigens you could go to an Antigram and see its different variations, theres ABO, Rh, Kell, Kidd, Diego, Duffy, M, N, S, Lewis, Lutheran and many more
I tried to donate blood once, but apparently they didn't want it. All they did was asking me stupid questions like: "Where did you get that barrel from?"
They asked me to donate blood, a few hours later, they came into the room, drunk as hell, and asked me what was in my blood. Told them that it was pure Scotch whisky!
As a blood banker, thanks for this great video! One sticking point though: doctors don't do antibody screening or crossmatching, Medical Laboratory Scientists/Technologists do. The doctors rely on us to get safe blood for their patients.
As an individual who has an almost non existent immune system. Plus I have a very rare type of anemia. I have to have blood transfusions often. Sometimes every two weeks. I thank everyone who donates their blood.
Are you a vampire? Next thing you are saying is that you despise the sun? :P Next time you get a blood transfusion, consider wearing a cape and fangs? :P
That's how I will forever remember my blood type. I have to get my blood taken frequently & testing done so they ask sometimes. 😂 Be positive! B+ atleast I'll never forget. Lol
Hi, an analyst in a bloodserology lab here. It's literally my job to do what you just described. I saw you missed a couple of spots. One being that the reason that AB0 and RhD have such a big impact is that they ALWAYS make antibodies, in fact the antibodies are present if everyone who doesn't have the antigen (because of gut microbes that have similar structures). Another thing that doctors can do is take blood from yourself if you have a rare blood type and then give it back once you need it (for instance with a planned surgery or pregnancy). Also, the screening you imply where you test for unexpected antibodies and crosstest with the donor blood? Unlike what you imply, that ALWAYS happens. It's an international prerequisite.
Ancient reptilian blood line. Imagine humans evolving to kill their own child during child birth. The weak die, strong live. Nowadays even the weak get to live.
Just want to point out: doctors do not, I repeat, do not screen for unexpected antibodies. They order that to be done, your friendly medical Lab scientist does the actual work.
Important to understand "screening and cross-matching" is NOT done by doctors. It is done by Medical Lab Scientists in the lab. With a little knowledge, practically anyone can do the ABORh blood drop screening cards but the more complicated stuff is done in the lab by lab people who understand it. Credit where credit is due!
Thank you lab scientists, for both the pounds of blood they've stolen from me over the years and that one time they put sticky electric things under my nipples for science Modern medicine is WILD
I once held 2 bags of blood by the same donor but taken 10 years apart. One had been frozen for that long and the second was taken because they wanted 2 bags available before the person with rare antibodies gave birth. I love when these episodes are about my work stuff.
Monica Elaina Monica Elaina yup, unfortunately it is a disorder too, often called Rh deficiency syndrome. Rh antigens play a role in maintaining the integrity of the red blood cell, so Rh null people have more fragile RBC. Since these cells are more fragile, they break down more easily than normal RBCs, leading to anemia. Granted, I think most Rh null patients compensate for this anemia by producing more RBCs at once, but I’m not quite sure about that.
I learned recently that I have selective IgA deficiency. So one type of antibody is missing from my body. Sometimes when people with selective IgA deficiency receive transfusions, they go into shock, because their body reacts badly to encountering IgA antibodies fof the first time. Good to know I guess.
I think they simply need to prepare the PRBC with washed saline, and that will help elimnate the IgA in blood. Blood transfusions have many ways of prepartion to help specific people as enxample there is Washed PRBC as in your situation is helpful, some people need Filtered PRBC, or Irradiated PRBC ( depending on their immune status, organ transplant, etc.)
MythoVirus is correct. Washed PRBC's are the product of choice for people who experience anaphylactic transfusion reactions most commonly due to IGA deficiency. However typically a person who is IGA deficient won't have a reaction the first time due to the body not having made the antibodies against IGA, it's typically the second exposure onward that is the problem.
@@gustavoguti27 Yeah, but O+ blood can be given to anyone with the Rh antigen. So, it's still in high demand, especially since AB+ is more rare. But, every donation helps!
I absolutely loved this episode! As a biochemistry graduate I learned that there were many more antigens in the blood, but I didnt know why we mainly focused for Ab/Rh for transfusions. Thanks for the video! Could it be possible to make a video on the reason for the difference in the immune response for Ab/Rh groups compared to the others (explained from a molecular and evolutionary perspective)?
Will you guys do a deeper dive into this topic!! Like maybe a 30 minute special about antigens and blood and what each system is and how they work in conjunction with eachother
Where are my fellow MTs?! I mostly work in Micro and Chemistry, but I just want to say I have so much respect for you guys. Keep being the total bosses you are!
I'm a generalist and work everything, but blood banking was always the most intimidating. then again my instructor during school was quite...terrifying
Last time I went to give blood I was informed I'm CMV negative which means my blood is good for babies and the immunosupressed. That and being O- kinda makes me a superhero
shadebug that's amazing, i hope you'll donate blood with relative frequency, and inform the nurses there of the importance of your blood. Save some lives girl
My choir meets down the road from the donation centre off Oxford Street so it's normally less than four months between donations, I just book the next session while I'm eating my biscuits. That and last time I went there was nobody in for platelet donation so I got to use a comfy chair. Don't think that telling them is necessary; it must be on my file or else how would they have known to tell me?
I’m immunosuppressed! I have Chron’s disease and with that comes a crappy immune system/meds that suppress my immune system. I needed a blood transfusion once during surgery, and it saved my life.
My brother is AB- so fairly rare blood type. He donated blood and when he moved from the east coast to go to college in the west, they called him at home out there to give him the address of the nearest blood donation place.
@@jeannie6011 Yeah, I have AB- as well. We're apparently 1% of the population. You are right to an extent. Our blood alone is not as useful as O- for example, but our plasma and platelets are. We are universal plasma and platelets donors. Which is also very useful.
As a former Med Tech, I have stories for days about the joys of typing out dozens of units to find c e Jk(a) Jk(b) negative donor units whose surgeon didn't think about giving us a heads up days before surgery to have special blood on hand. Made me a better PA lol
Cool video, slightly disappointed. My dudes, we perform type AND SCREENS on every individual getting blood. No one’s ever going to get blood on an ABO type alone (emergency situations aside). Also cross matches on every individual. Even in emergency situations, we keep segments of blood sent in emergencies so we can perform these tests retroactively when a blood draw is available. Also clinical laboratory scientists perform these tests, not physicians. Most doctors scratch their heads when the extended blood groups are in play. Maybe consult someone who works in immunohematology (hint: scientists) before thinking “ah I guess a doctor does this right?”
I work in the frozen blood bank in the UK and work with some of the rarest blood types. A lot of rare blood is stored frozen in banks all over the world for up to 30 years, because if it was last as a normal donation it would only last for just over a month (depending on the country) and so might not be available when a patient needs it. I myself have sent and received blood from all over the world thanks to the international rare donor panel.
It's a regulatory requirement by laboratory accreditation agencies and government agencies in the USA. You can however do electronic crossmatching which checks historical and current blood typing and antibody screen results against a donor unit in the computer system.
When I was in highschool our class went to a biology exhibition in a university and they were demonstrating how to test your blood group, I tested my own blood group there although I'm afraid of needle but I was so dang happy cause I thought it was so cool 😂 .
I'm a Specialist Biomedical Scientist, specialising in Transfusion. I have to say this video is orders of magnitude better than anything else I've seen online (EDIT: with the exception of BBguy)! I can't fault any of it. I especially love how you said Rh instead of Rhesus. I've seen an article about Rh null in a big newspaper before that thought Rh null blood is *literally* golden. Good work!
@@mrwog82 They're a similar problem, but on different antigens. Rh null affects the Rh antigens, Bombay affects ABO antigens. The biochemistry of how ABO and Rh are synthesised is quite different.
As a med lab tech just waiting to hear about Bombay blood type because we had to learn about it even though our chances encountering it are practically nill. Edit- doctors do not perform blood bank testing that’s my job.
There's actually all of the negative RH blood types in my family :D My dad is O-, my mum is AB- and me and my eldest brother is A-, whereas my older brother is B-. So if someone we know needs a blood transfusion, our family has the blood types for it XD (Since Negatives can donate blood to both positive bloodtypes and negative blood types XD) (Then again, they actually only need my dad, since O- can donate to all RH positive and negative blood types)
Got my blood drawn today since I have surgery next week. Part of me is super excited to see where I fall on that Japanese personality type theory, but I can't deny stuff like this is also in the back of my mind.
Hey SciShow, doctors don't do antibody screens or crossmatches! Medical laboratory technicians, scientists, and technologists do. We're a pretty quiet part of the healthcare team, but we are the ones doing a majority of the science that goes into ensuring your health.
Yeah that! Almost ALL the testing that gets done gets done by us lab rats. That glucose test, the cholesterol, all but the most obscure ones. And even then, it's us laboratory scientists that do the actual test work, measuring and mixing all the cocktails, then the doctor reviews the results and make the actual call of the result.
Ryan K. well yeah, but whole blood is easy! platelets is a 2-4 hour commitment, and I live near a cancer research center.... so I donate platelets as often as they need...
Annmarie Myers our platelets clot better than all other types when transfused. they want you for trauma vics and cancer patients. that, and there's ALWAYS a blood shortage
Well... I've learned so much from this video that I have to watch it a few more times. Great information that seem updated since I first heard of blood types. I say thank you for caring enough to give us some decent education.
I graduated Med Tech school in 1983. It was complicated then. Now, in 2019 there are so many known blood antigens the book (AABB Tech Manual) is 3 times as thick!
Thank you for explaining this! I've always wondered what makes some people still have (mild) transfusion reactions even though they were type and screened; the presence of many other antigens that the body only sees as mini threats makes sense. [:
I have no idea. She may have done it again more recently. But I no she made it a point to tell my dad my mom and my other sister about her blood type. Not quiet sure if they have had her put more away though
bnet sucks yes, but it depends on how you store it. I’m a clinical laboratory science student who just finished his blood banking rotation so a lot of this stuff is fresh in my mind atm. Most blood is stored in a refrigerator between 1-6 degrees Celsius. Depending on the anticoagulant used in the donation process, these can last anywhere between 21 to 42 days. However, blood products of rare blood types are often frozen in glycerol using a controlled rate freezer. If you freeze these cells at less than -18 Celsius, they last for a year, and at less than -65 Celsius, they last for 10 years. Those with Rh null are a different story though. Their RBCs tend to be more fragile since Rh antigens play a role in maintaining red cell integrity. This makes it hard to freeze them, even in a controlled rate freezer, since they are more easily damaged by ice crystals. Therefore, it is much harder to preserve Rh null cells through freezing.
The worst part is that you find out you're adopted while you learn about blood types.. Happened to a friend of mine back in 6th grade. She looked like she could be a combination of her adoptive parents, but the mom being A and the dad being AB didn't match with her being O.
Learning you're adopted is the best case scenario in that case, i think. Zhe other option would be ... infidelity ... (well, or the mom/dad is a chimera)
My family still says I'm there child. Yet my mom is B+ & my dad is O+ & I'm...A-.....🤷♀️ to my knowledge all my 4 brothers are rh+ & none are A...so....
I have a weird-ish blood type! I found out when I wanted to donate a kidney. A+, non-A1. (Meaning that they didn't test to find what specific variant of A it is, but they know it's not the most common one.) It only has about 20% of the the A markers that A1 has. That means that, for donating/receiving blood, it's A, but for organ donation some of my organs can go to O recipients. me: "Sooo it's like A-light?" Doc: "... Yes. Yes! That's exactly right. I'm going to use that explanation next time."
Adaginy hi there! I’m a clinical lab science student who just finished his clinical rotation in the blood bank, so I think it’s awesome that you have a different variant of the A antigen! More than likely, you just have the A2 variant. I don’t have the exact stats, but I remember learning in class that around 80% of group A people are A1, 19.9% are A2, and 0.1% are some other, rarer variant of the A antigen!
When I first donated blood, at a Medical Center where I worked as a student,they told me that I was O +/- (positive as a donor, negative as a recipient.) I have SOME of the Rh variants, but not all.
@@robertrosenthal7264, yeah, but I think you have to know it if your life is on the line, it really is important. I keep meaning to ask my Doctor but always forget, maybe writing this will help.
Art Dent if they’re not sure what blood type you have in an emergency situation they just give you O-. That’s why they are always practically begging people with that blood type to donate.
Sometimes. There is this blood group called 'Duffy' which has an A and B form (FyA and FyB) and also has an unstable form Fy. The FyA and FyB are used by malaria to enter your red blood cells and reproduce, which makes you sick. So having the unstable Fy variant is an advantage, and significantly higher rates of Fy are seen in places like Mozambique compared to areas where malaria isn't prevalent. As for the ABO system, variation is likely just because it doesn't cause any harm. The 'ancestral' variant is A, but it mutated to form B, and a different mutation caused an enzyme to stop working which results in O. This doesn't really cause any problems (except for donating blood) so there wasn't really selective pressure for or against these blood groups*
My friend got hit by a bus while crossing the road together on our bikes. I immediately ran up to him and called an ambulance. He was bledding heavily. I'll always remember his last words. He kept telling be to "be positive." Miss you man. :(
_Don’t let the Japanese find out about this; they’ll go nuts!_ Also, I’d love to see a Papers Please mod where you play as an immune cell checking the antigens of various body/bacterial cells.
My exhusband is A- and I'm B+. We had 2 children a female A- and a son B-. When he was going to have an operation neither of us could be used for an emergency. That has concerned me for years especially since B- is not a common blood type.
@@dinkledankle According to the NIH : "The functions of many of the blood group antigens are not known, and if they are missing from the red blood cell membrane, there is no ill effect. This suggests that if the blood group antigens used to have a function, e.g., one particular blood group antigen made red blood cells more resistant to invasion from a parasite, it is no longer relevant today." www.ncbi.nlm.nih.gov/books/NBK2264/
Me about sleep at 12AM believing that there are only four blood types
YT notification: “There are millions of blood types”
Me: *_”I don’t need sleep, I need answers!”_*
This is actually what's happening to me right now. How freaky. I didn't even know it was 12am. Are you a wizard?
3am for me
@@200odd300 its 6 for me now which turns out to be 2, and i didnt mind when 6 turned out to be 9 either...J.H. rip 🎸🎶🎤😎
I knew there were rare blood types but didn’t know exactly how it worked or how many variations there could be
Évariste Galois
If you are really interested there’s a class named blood bank. It’s hard, yet it teaches these different variations of blood types , Rh itself has many different variations ,
Example:
DEc/cE
DEC/ce
Dce/ce ... etc
There upon many different antibodies/ antigens you could go to an Antigram and see its different variations, theres ABO, Rh, Kell, Kidd, Diego, Duffy, M, N, S, Lewis, Lutheran and many more
I tried to donate blood once, but apparently they didn't want it. All they did was asking me stupid questions like: "Where did you get that barrel from?"
They're so picky about it, I was once rejected because apparently they don't like it when the blood has pieces of flesh and bone in it.
They asked me to donate blood, a few hours later, they came into the room, drunk as hell, and asked me what was in my blood. Told them that it was pure Scotch whisky!
This comment is so underrated
Yeah, they kept asking dumb questions like “whose blood is this” and “wait, are you that serial killer on the news?”
@ɮօʊռċɛ օʄʄ relevant because...?
I don't want to brag but everytime I take a blood test I get an A+
ROFL! 🤣 😂 😅
hehe 😛
It must be due to skill and not because you B+
That's better then me, I always get a B+.
Not in an English Test
As a blood banker, thanks for this great video! One sticking point though: doctors don't do antibody screening or crossmatching, Medical Laboratory Scientists/Technologists do. The doctors rely on us to get safe blood for their patients.
Fellow blood banker! I was just about to comment the same thing!
If I make a deposit in the blood bank what interest rate can you offer me?
"Sticking point" 🤣🤣🤣
I just graduated from a lab tech program, came here to say this!
Still can’t stand the smell of DTT, I don’t understand how y’all can keep doing that
As an individual who has an almost non existent immune system. Plus I have a very rare type of anemia. I have to have blood transfusions often. Sometimes every two weeks.
I thank everyone who donates their blood.
I'm donating tomorrow! 💪
Are you a vampire? Next thing you are saying is that you despise the sun? :P
Next time you get a blood transfusion, consider wearing a cape and fangs? :P
Yeah ok anemia huh rare huh ok
@@chosenpeople5881 what's your problem? I highly doubt you know a stranger's medical situation better then themselves
I'm curious. What kind of anemia do you have? I hope one day you don't have to go through so many treatments to feel better. 🤔👍
B negative, although trying to be positive
so dumb LOL. nice one
Kim van Oers Keep your chin up. You can change blood types.
That's how I will forever remember my blood type. I have to get my blood taken frequently & testing done so they ask sometimes. 😂
Be positive! B+ atleast I'll never forget. Lol
I'm O positive but it doesn't suit me since I'm pretty negative.
see mine can't really be a pun... :/
Jesus, how many channels does Hank have, everytime I stumble upon a new cool science channel Hank is the producer.
ALL OF THEMMMM
Hank is the embodiment of science itself. You can't have science without Hank Green.
Hank is the new bill nye
#HankEmpire
Hank Green is especially fecund.
Hi, an analyst in a bloodserology lab here. It's literally my job to do what you just described. I saw you missed a couple of spots. One being that the reason that AB0 and RhD have such a big impact is that they ALWAYS make antibodies, in fact the antibodies are present if everyone who doesn't have the antigen (because of gut microbes that have similar structures).
Another thing that doctors can do is take blood from yourself if you have a rare blood type and then give it back once you need it (for instance with a planned surgery or pregnancy).
Also, the screening you imply where you test for unexpected antibodies and crosstest with the donor blood? Unlike what you imply, that ALWAYS happens. It's an international prerequisite.
Taking your own and giving it back to you... Isn't that doping!!
All I have is Rh-Disappointment running through my veins
This pun is also a disappointment.
Ancient reptilian blood line. Imagine humans evolving to kill their own child during child birth. The weak die, strong live. Nowadays even the weak get to live.
Ah, same group
Relatable
I lost two babies, then starting getting the antiglobulin shots, so thankfully have two lovely daughters.
Just want to point out: doctors do not, I repeat, do not screen for unexpected antibodies. They order that to be done, your friendly medical Lab scientist does the actual work.
This! We exist. We go unknown and help keep you alive daily.
@@ereavnydae i really appreciate y'all. Y'all rock 🤘
👆👆👆👆👆 THIS.
Important to understand "screening and cross-matching" is NOT done by doctors.
It is done by Medical Lab Scientists in the lab.
With a little knowledge, practically anyone can do the ABORh blood drop screening cards
but the more complicated stuff is done in the lab by lab people who understand it.
Credit where credit is due!
Thank you lab scientists, for both the pounds of blood they've stolen from me over the years and that one time they put sticky electric things under my nipples for science
Modern medicine is WILD
This once again shows life is more complex than we think it is.
than you think.
@@drewjohnson9498 Ok, well, at least we know they'll never discover a 4th state of matter.
/s
@@drewjohnson9498 wtf is intersex
@@ghuegel plasma?
@@27siddarth DAMMIT!!!
Ok, well, at least we know they'll never discover a 5th state of matter.
I once held 2 bags of blood by the same donor but taken 10 years apart. One had been frozen for that long and the second was taken because they wanted 2 bags available before the person with rare antibodies gave birth. I love when these episodes are about my work stuff.
My uncle was 0RH null, and he was a donor until he started having health issues in his 60s.
I thank your uncle for all his contributions.
Wow. He is one of only 48 people discovered to date that are RHnull!
I read RH null is a blood disorder. My husband is 27 and said he just said he found out he is RH null.
Monica Elaina Monica Elaina yup, unfortunately it is a disorder too, often called Rh deficiency syndrome. Rh antigens play a role in maintaining the integrity of the red blood cell, so Rh null people have more fragile RBC. Since these cells are more fragile, they break down more easily than normal RBCs, leading to anemia. Granted, I think most Rh null patients compensate for this anemia by producing more RBCs at once, but I’m not quite sure about that.
Im also part of the RH-Null club
I learned recently that I have selective IgA deficiency. So one type of antibody is missing from my body.
Sometimes when people with selective IgA deficiency receive transfusions, they go into shock, because their body reacts badly to encountering IgA antibodies fof the first time.
Good to know I guess.
I used to have to get Ig infusions because I was diagnosed with a deficiency too
(Everything sucked the day or two after I had them)
I think they simply need to prepare the PRBC with washed saline, and that will help elimnate the IgA in blood.
Blood transfusions have many ways of prepartion to help specific people as enxample there is Washed PRBC as in your situation is helpful, some people need Filtered PRBC, or Irradiated PRBC ( depending on their immune status, organ transplant, etc.)
MythoVirus is correct. Washed PRBC's are the product of choice for people who experience anaphylactic transfusion reactions most commonly due to IGA deficiency. However typically a person who is IGA deficient won't have a reaction the first time due to the body not having made the antibodies against IGA, it's typically the second exposure onward that is the problem.
CVID?
They told me I had type A blood
But it was a Type O
STOMP MY HEEL AND SLAP MY KNEE U LITTLE JOKESTER! SLOW DOWN!
Good one...
*ba dum tss!* 🥁 😂 🤣 😅
Ah. Hank
They found out it was a typo after the transfusion killed him however.
The nurse told me I had the same blood type as her.
I was like, O-Snap!
I'm O negative and have blue genes. It's in the denim group.
This is gold.
Blue genes? I don't get it
@@limiv5272 blue jeans
This video is Bloody Brilliant.
You clot
@@beridot2615 You bloody legend
You three are an A+
These jokes are giving me a heart attack
"Hank Green's soothing narration" - I'm sold.
O-pos. The Red Cross practically begs me to show up every time there's a blood drive.
0- (negative) is the universal donor, not the 0 pos
Gustavo Gutierrez O pos is super rare though, that's why
@@gustavoguti27 Yeah, but O+ blood can be given to anyone with the Rh antigen. So, it's still in high demand, especially since AB+ is more rare. But, every donation helps!
@@literalantifaterrorist4673 nop, it is the most common. But can be given to almost everyone
O pos is the most common blood group. But all donations are always needed and help save lives.
I absolutely loved this episode! As a biochemistry graduate I learned that there were many more antigens in the blood, but I didnt know why we mainly focused for Ab/Rh for transfusions. Thanks for the video! Could it be possible to make a video on the reason for the difference in the immune response for Ab/Rh groups compared to the others (explained from a molecular and evolutionary perspective)?
Dracula doesn't care about your blood type, he will drink it anyway
Yes he will.
He's kind of batty anyway.
Clearly in the case of Renfield, there is at least one blood type Dracula will not drink.
Christel Headington I’ve heard O or A is more delicious
Sounds like the Blood-Mobiles. Bunch of vampires on wheels.
My blood type is Water/Flying; it's doubly weak to Electric type so I have to be extra careful.
@Noah Kenney same double
Did you just use the word "soothing" to describe Hank's voice?
Its pretty soothing in those videos. I love it.
Yeah Hank usually has a bit of a frantic vibe, but in these videos he speaks calmly and softly, and it's super chill. I love it too!
Hank's voixe there is completleeeeey difrent
@Mark Bradley Hank doesn't wear earrings. Do you mean Michael from this video? I like them
Rhythmically slowfast
Will you guys do a deeper dive into this topic!! Like maybe a 30 minute special about antigens and blood and what each system is and how they work in conjunction with eachother
_when Michael advertises Journey to the microcosmos but you already know it and are subscribed_
*I am speed*
I was early to the first episode.
*God Speed* mu fellow viewer!
But can you outrun the pain?
5:14 it's a fantastic channel, I love it, deserves more recognition! :D
Where are my fellow MTs?! I mostly work in Micro and Chemistry, but I just want to say I have so much respect for you guys. Keep being the total bosses you are!
Blood banking isn't hard but it is intimidating. I've been MedTeching for 35 years and still get nervous if I'm working in Blood Bank
I'm a generalist and work everything, but blood banking was always the most intimidating. then again my instructor during school was quite...terrifying
@@mycobacteriem2540 I think the instructors are ruthless and intimidating on purpose. Mine was the same way!
Last time I went to give blood I was informed I'm CMV negative which means my blood is good for babies and the immunosupressed. That and being O- kinda makes me a superhero
shadebug that's amazing, i hope you'll donate blood with relative frequency, and inform the nurses there of the importance of your blood. Save some lives girl
How often do u donated
My choir meets down the road from the donation centre off Oxford Street so it's normally less than four months between donations, I just book the next session while I'm eating my biscuits. That and last time I went there was nobody in for platelet donation so I got to use a comfy chair.
Don't think that telling them is necessary; it must be on my file or else how would they have known to tell me?
Superman are you my father 😂
I’m immunosuppressed! I have Chron’s disease and with that comes a crappy immune system/meds that suppress my immune system. I needed a blood transfusion once during surgery, and it saved my life.
My blood type is uint16
You. I like you.
U an alien
Be careful! That type is incompatible with Rh negative. Ask me how I know. It put me in a cast.
Mine is DWORD
Ah, yes, the rarely-used C++ blood type system!
Check out Journey to the Microcosmos here: th-cam.com/users/microcosmos
No
My brother is AB- so fairly rare blood type. He donated blood and when he moved from the east coast to go to college in the west, they called him at home out there to give him the address of the nearest blood donation place.
Ab- blood types can accept blood from any donee with - blood. He may be rare but is not exceptionally useful
@@jeannie6011 Yeah, I have AB- as well. We're apparently 1% of the population. You are right to an extent. Our blood alone is not as useful as O- for example, but our plasma and platelets are. We are universal plasma and platelets donors. Which is also very useful.
I'd say your narration is the most soothing.
Blood types are interesting, especially when you look at nonhuman blood types. I love science.
Non human blood types.....means there are non humans among us. Means we should investigate that............
@@VioletLife8 UFOreal? xD I think he means bugs or animals tho
As a former Med Tech, I have stories for days about the joys of typing out dozens of units to find c e Jk(a) Jk(b) negative donor units whose surgeon didn't think about giving us a heads up days before surgery to have special blood on hand. Made me a better PA lol
Cool video, slightly disappointed. My dudes, we perform type AND SCREENS on every individual getting blood. No one’s ever going to get blood on an ABO type alone (emergency situations aside). Also cross matches on every individual. Even in emergency situations, we keep segments of blood sent in emergencies so we can perform these tests retroactively when a blood draw is available. Also clinical laboratory scientists perform these tests, not physicians. Most doctors scratch their heads when the extended blood groups are in play.
Maybe consult someone who works in immunohematology (hint: scientists) before thinking “ah I guess a doctor does this right?”
I work in the frozen blood bank in the UK and work with some of the rarest blood types. A lot of rare blood is stored frozen in banks all over the world for up to 30 years, because if it was last as a normal donation it would only last for just over a month (depending on the country) and so might not be available when a patient needs it. I myself have sent and received blood from all over the world thanks to the international rare donor panel.
Unless things have changed in the last few years, cross matching is always done before administering blood- except in emergency situations, of course.
It's a regulatory requirement by laboratory accreditation agencies and government agencies in the USA. You can however do electronic crossmatching which checks historical and current blood typing and antibody screen results against a donor unit in the computer system.
I worry about Hank burning out with all the projects he takes on, but I'm always so happy to see him and the childlike wonder he brings.
When I was in highschool our class went to a biology exhibition in a university and they were demonstrating how to test your blood group, I tested my own blood group there although I'm afraid of needle but I was so dang happy cause I thought it was so cool 😂 .
I'm a Specialist Biomedical Scientist, specialising in Transfusion. I have to say this video is orders of magnitude better than anything else I've seen online (EDIT: with the exception of BBguy)! I can't fault any of it. I especially love how you said Rh instead of Rhesus. I've seen an article about Rh null in a big newspaper before that thought Rh null blood is *literally* golden. Good work!
Question for you then. Is Rh null the same as Bombay or are they different?
@@mrwog82 They're a similar problem, but on different antigens. Rh null affects the Rh antigens, Bombay affects ABO antigens. The biochemistry of how ABO and Rh are synthesised is quite different.
@@KX36 Thanks!
As a med lab tech just waiting to hear about Bombay blood type because we had to learn about it even though our chances encountering it are practically nill. Edit- doctors do not perform blood bank testing that’s my job.
DioneN BOMBAY PHENOTYPE!😂
Always refreshing to see a video with Michael in it.
There's actually all of the negative RH blood types in my family :D My dad is O-, my mum is AB- and me and my eldest brother is A-, whereas my older brother is B-.
So if someone we know needs a blood transfusion, our family has the blood types for it XD (Since Negatives can donate blood to both positive bloodtypes and negative blood types XD)
(Then again, they actually only need my dad, since O- can donate to all RH positive and negative blood types)
Hank greens’ soothing narration? Seriously?!? The guys voice is Beyond grating
Interesting. I knew there were other antibodies, I hung enough blood products working as a nurse, but I didn't know there were that many! Thanks!🤓
Got my blood drawn today since I have surgery next week. Part of me is super excited to see where I fall on that Japanese personality type theory, but I can't deny stuff like this is also in the back of my mind.
Is blood supposed to taste sweet? Mine tastes sweet- Oh, I could be diabetic.
Hey SciShow, doctors don't do antibody screens or crossmatches! Medical laboratory technicians, scientists, and technologists do. We're a pretty quiet part of the healthcare team, but we are the ones doing a majority of the science that goes into ensuring your health.
Yeah that! Almost ALL the testing that gets done gets done by us lab rats. That glucose test, the cholesterol, all but the most obscure ones. And even then, it's us laboratory scientists that do the actual test work, measuring and mixing all the cocktails, then the doctor reviews the results and make the actual call of the result.
I have A+, the red cross won't leave me alone. You donate platelets once and they think you're a mule
Phone rings...hello this is the red cross...we need your blood!
You: im sorry i just got back from the area of Africa that Ebola is rampant!
Better off then having O-! I can literally donate to everyone...
Ryan K. well yeah, but whole blood is easy! platelets is a 2-4 hour commitment, and I live near a cancer research center.... so I donate platelets as often as they need...
I have A+ too they're always calling me too
Annmarie Myers our platelets clot better than all other types when transfused. they want you for trauma vics and cancer patients. that, and there's ALWAYS a blood shortage
That was so incredibly interesting, thank you for sharing.
I've never been this early to a video...so first? what do I do lol. tell Hank I love him, thanks
not early either
I love you too.
@@bubblehank3412
What did you do to Muscle Hank?
Well... I've learned so much from this video that I have to watch it a few more times.
Great information that seem updated since I first heard of blood types. I say
thank you for caring enough to give us some decent education.
I graduated Med Tech school in 1983. It was complicated then. Now, in 2019 there are so many known blood antigens the book (AABB Tech Manual) is 3 times as thick!
O+... I cant share with everyone like O- but I'm the most common as far as I know.
I think all RH neg and RH null cannot receive your O pos blood.
But all possitives can receive your blood.
O + is the most common one, mine is also O+
Thank you for explaining this! I've always wondered what makes some people still have (mild) transfusion reactions even though they were type and screened; the presence of many other antigens that the body only sees as mini threats makes sense. [:
geez i sure wonder the name of the *ONLY* person to have the *DIEGO* type blood.
Many of the names of the other blood groups come from the family in which they were first seen.
There's a non-zero chance Diego was the doctor who found it rather than the person they found it in.
Great video! Just one thing: it’s not doctors doing the compatibility testing. That would be medical technologists like me!
Thank you for your work, although with that last name idk if I'd trust you with my life ;)
My blood type is B+ but I'm always depressed
Same
Same
Watching this at 3am while a raging thunderstorm outside. I like jis calming voice
Wow, didn't knew the Journey to the Microcosmos channelwas related to Sci Show. It's a great channel, check it ou peeps
Man the amount of research did, impressive!
My older sister is RH- they made her save a bunch of blood in a blood bank 5 years ago
I have no idea. She may have done it again more recently. But I no she made it a point to tell my dad my mom and my other sister about her blood type. Not quiet sure if they have had her put more away though
bnet sucks yes, but it depends on how you store it. I’m a clinical laboratory science student who just finished his blood banking rotation so a lot of this stuff is fresh in my mind atm. Most blood is stored in a refrigerator between 1-6 degrees Celsius. Depending on the anticoagulant used in the donation process, these can last anywhere between 21 to 42 days. However, blood products of rare blood types are often frozen in glycerol using a controlled rate freezer. If you freeze these cells at less than -18 Celsius, they last for a year, and at less than -65 Celsius, they last for 10 years. Those with Rh null are a different story though. Their RBCs tend to be more fragile since Rh antigens play a role in maintaining red cell integrity. This makes it hard to freeze them, even in a controlled rate freezer, since they are more easily damaged by ice crystals. Therefore, it is much harder to preserve Rh null cells through freezing.
The worst part is that you find out you're adopted while you learn about blood types.. Happened to a friend of mine back in 6th grade. She looked like she could be a combination of her adoptive parents, but the mom being A and the dad being AB didn't match with her being O.
Learning you're adopted is the best case scenario in that case, i think. Zhe other option would be ... infidelity ...
(well, or the mom/dad is a chimera)
My family still says I'm there child. Yet my mom is B+ & my dad is O+ & I'm...A-.....🤷♀️ to my knowledge all my 4 brothers are rh+ & none are A...so....
I have a weird-ish blood type! I found out when I wanted to donate a kidney. A+, non-A1. (Meaning that they didn't test to find what specific variant of A it is, but they know it's not the most common one.) It only has about 20% of the the A markers that A1 has. That means that, for donating/receiving blood, it's A, but for organ donation some of my organs can go to O recipients.
me: "Sooo it's like A-light?"
Doc: "... Yes. Yes! That's exactly right. I'm going to use that explanation next time."
Adaginy hi there! I’m a clinical lab science student who just finished his clinical rotation in the blood bank, so I think it’s awesome that you have a different variant of the A antigen! More than likely, you just have the A2 variant. I don’t have the exact stats, but I remember learning in class that around 80% of group A people are A1, 19.9% are A2, and 0.1% are some other, rarer variant of the A antigen!
P.S I love that explanation of A antigen subgroups, and I think I may use it from now on as well 😆
When I first donated blood, at a Medical Center where I worked as a student,they told me that I was O +/- (positive as a donor, negative as a recipient.) I have SOME of the Rh variants, but not all.
You're either positive or negative. You can't be both
@@Iosepalias he's got a D variant. It's like a weak expression of being Rh positive.
My grandson is B +/- he has weak D.
I've read too much fanfiction to listen to you say ABO without a visceral reaction
Makes the Bloodless Surgery Centers popping up around the world seem mighty inviting!
What about how many crip types?
Journey to microcosmos is rad yo. great at end of night when sleepy
BY THE WAY! Doctors dont do cossmatches, MEDICAL LAB SCIENTISTS do! 🙂🙂🙂🙂
But what if those medical lab scientists have PhDs? Then they’d be doctors 🤔🤔🤔
I have checked out and subscribed in the microcosm
I remember that I'm type A, thank you grade 10 biology, but I forget if it's positive or negative, oops;)
Is your name really Arthur Dent? 😄
That's a rather important detail to forget, but most people don't get asked it on a regular basis either.
@@LadyAneh, well, the email address that goes with this account is FordPerfect42..., Prefect was already taken, doh. You figure it out;)
@@robertrosenthal7264, yeah, but I think you have to know it if your life is on the line, it really is important. I keep meaning to ask my Doctor but always forget, maybe writing this will help.
Art Dent if they’re not sure what blood type you have in an emergency situation they just give you O-. That’s why they are always practically begging people with that blood type to donate.
The distance from UK to Kamerun is about 6000 kilometers.
I’ve noticed Michael doesn’t blink. I can’t watch. His episodes are now a podcast.
The one blink at the end was like he was mocking me.
Now I can’t unsee this
Aphro Apologies - Sharing the horror. I can’t unsee it either.
There's another at 0:22, at the video splice. New clip starts with eyes closed.
And a mid-clip blink at 1:21.
Matthew Gies Well spotted! Not the same tension breaker as seeing his eyes actually close.
He blinks just before 4:00
This man is not human. He rarely blinks in this video witch is a form of hypnotic suggestion. Hes a lizard. Rh-
If his hypnotic suggestion was to make out with him, it got through to me 😘
This will make blood type horoscopes much more complicated...😅
I love the new hairstyle!
Maybe if you donate blood and you have a rare type, you could get your own blood back
I can't stop admiring this guys hair.
O negative. Im pretty much a hero.
I really really like your voice and way of speaking!!
Blood type testing is the only test where A+ is the second worst grade.
Ever since I found out HH exists as a group in place of ABO I’ve been kinda amazed at all this.
But why are there millions of blood types around my...
Wait...
AhtzeeGaming ?
throwback time
been watching journey to the microcosm since episode one, super interesting stuff
Where my AB- 's at?
I've got a question: is there an evolutionary explanation to such a huge diversity of blood type ?
Thanks for this video !
Sometimes. There is this blood group called 'Duffy' which has an A and B form (FyA and FyB) and also has an unstable form Fy. The FyA and FyB are used by malaria to enter your red blood cells and reproduce, which makes you sick. So having the unstable Fy variant is an advantage, and significantly higher rates of Fy are seen in places like Mozambique compared to areas where malaria isn't prevalent.
As for the ABO system, variation is likely just because it doesn't cause any harm. The 'ancestral' variant is A, but it mutated to form B, and a different mutation caused an enzyme to stop working which results in O. This doesn't really cause any problems (except for donating blood) so there wasn't really selective pressure for or against these blood groups*
1:55 I didn't know there are people with actual blue blood.
My friend got hit by a bus while crossing the road together on our bikes. I immediately ran up to him and called an ambulance. He was bledding heavily. I'll always remember his last words. He kept telling be to "be positive."
Miss you man. :(
_Don’t let the Japanese find out about this; they’ll go nuts!_
Also, I’d love to see a Papers Please mod where you play as an immune cell checking the antigens of various body/bacterial cells.
How about a session on matching tissue types for organ and marrow transplants ?
science 🔬 and magic 🧝♂️ at this point are the same..
This was very informative, wow! Thank you.
Kinda cool
Or warm, like blood.
My exhusband is A- and I'm B+. We had 2 children a female A- and a son B-. When he was going to have an operation neither of us could be used for an emergency. That has concerned me for years especially since B- is not a common blood type.
*blood puns anyone?* 💪
Journey to the Microcosmos is an AMAZING channel
Is there any evolutionary advantage to these antigens?
Antibodies require antigens to work, so yeah, I'd say there is. Wouldn't be very easy to evolve without an immune system.
@@dinkledankle I'm talking about the specific antigens that determine blood type. Are you saying those antigens are used other places in the body?
@@dinkledankle It seems that a lack of the antigens does no harm to people with O- blood.
@@dinkledankle According to the NIH :
"The functions of many of the blood group antigens are not known, and if they are missing from the red blood cell membrane, there is no ill effect. This suggests that if the blood group antigens used to have a function, e.g., one particular blood group antigen made red blood cells more resistant to invasion from a parasite, it is no longer relevant today."
www.ncbi.nlm.nih.gov/books/NBK2264/
Excellent video! Journey to the Microcosmos is a great channel & everyone should subscribe to it.