Wouldn't the boat conformation have lower energy for the trans decalin, if there is a bulky group sitting axial in the chair conformation? I'm sitting with the exact same molecule set building decalins...
It's a good question! One I thought I was sure on, but decided to do some checking. I ran some rough molecular calculations and there is still a 1 kcal/mol difference in favour of the substituent (tBu) being axial in a trans-fused chair-chair decalin.
THIS is just what I wanna know!
Molecule model is really helpful to know stereochemistry.
Thank you for your excellent explanation!
I can't begin to tell you how much this helped. Thank you so much!
Very Very helpful Thanks sir. It would be nice if you would do a video on perhydrophenalene
Nice explanation sir 👏
Wouldn't the boat conformation have lower energy for the trans decalin, if there is a bulky group sitting axial in the chair conformation? I'm sitting with the exact same molecule set building decalins...
It's a good question! One I thought I was sure on, but decided to do some checking. I ran some rough molecular calculations and there is still a 1 kcal/mol difference in favour of the substituent (tBu) being axial in a trans-fused chair-chair decalin.
Thanks!
so clear!
Thank you.. This video makes it much easier to understand :)
This is brilliant, thank you so much
greatful to you
Thank you for this, helps a lot
love this video
1:18
thanks lots!
Thanks
Macher