Biotech CEO Jeff Galvin Explains Cell and Gene Therapy to Stony Brook Biomedical Engineering Society

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  • เผยแพร่เมื่อ 3 ม.ค. 2025

ความคิดเห็น • 34

  • @veshzain994
    @veshzain994 3 ปีที่แล้ว +2

    God Bless you Jeff - Thank you for giving us hope

  • @Mr.Majestic77
    @Mr.Majestic77 2 ปีที่แล้ว +2

    The possibility of combining AGT103-T and EBT-101 Therapies:
    In combining EBT-101 and AGT103-T, the patient would first take the gene and cell therapy treatment, AGT103-T, which involves HIV-specific CD4 T-cells that are genetically modified to resist HIV, by having a sample of peripheral blood cells collected from the patient and CD4 cells that recognize HIV’s Gag protein. A harmless lentivirus vector is then used to insert genes that disable CCR5 receptors, where HIV uses to enter cells. The modified CD4 cells are then multiplied and returned into the patient’s body.
    The same patient would then take the CRISPR-based one-time gene therapy, EBT-101, that will utilize AAV to deliver an intravenous infusion intended to functionally cure the HIV infection. The CRISPR cuts out or excise the HIV that has wrapped around the DNA cells. This therapy would harness the AAV at a relatively low dose to deliver the treatment, which would deploy CRISPR-Cas9 and two guide RNAs that target three sites within the HIV genome.
    Can two functional cures in AGT103-T and EBT-101 combine into one EBT-101 + AGT103-T sterilizing cure?

  • @ishingo7451
    @ishingo7451 3 ปีที่แล้ว +5

    Jeff, thank you for interesting story

    • @AmericanGeneTechnologies
      @AmericanGeneTechnologies  3 ปีที่แล้ว +5

      Thank you so much for your comment.

    • @baldevsamji7489
      @baldevsamji7489 3 ปีที่แล้ว +1

      Thanks you American science Tys God bless you

    • @Mr.Majestic77
      @Mr.Majestic77 2 ปีที่แล้ว +1

      @@AmericanGeneTechnologies
      Has American Gene Technologies thought about contacting and combining research with Excision Bio-Therapeutics (developers of EBT-101), which AGT103-T + EBT-101 can be merged into one treatment?
      With AGT103-T, the HIV therapeutic cure is a genetically modified cell product made from a person's own cells and EBT-101 is a therapeutic HIV cure using CRISPR-Cas9 & dual guide RNA as a therapy to eradicate HIV. EBT-101 is also in clinical trials.

  • @venkatimandi5885
    @venkatimandi5885 3 ปีที่แล้ว +3

    Hi jeff galvin everyone curiously waiting for your success, by God grace you will be a torchbearer and your name echoes as long as sun will arise.

  • @hindisongbollywood7792
    @hindisongbollywood7792 3 ปีที่แล้ว +6

    Cure from hiv possible in which year please save from hiv

  • @zeetalks4659
    @zeetalks4659 3 ปีที่แล้ว +7

    Jeff God bless your work ....I have been sending you message pls I want to have a chat with you if you don't mind

  • @albeettshuelderalberttshue802
    @albeettshuelderalberttshue802 3 ปีที่แล้ว +5

    May Archangel Rsphael enlighten you with the Green Light of Higher knowledge.

    • @Bantu_Doll
      @Bantu_Doll 3 ปีที่แล้ว +1

      Amen

    • @sarahmwendi506
      @sarahmwendi506 3 ปีที่แล้ว

      Amen. I can tell you are Catholic 😉

  • @diliplaishram4290
    @diliplaishram4290 3 ปีที่แล้ว +2

    I have a quest that when do hiv cure be available in market

    • @hindisongbollywood7792
      @hindisongbollywood7792 3 ปีที่แล้ว +2

      In 2025

    • @AmericanGeneTechnologies
      @AmericanGeneTechnologies  2 ปีที่แล้ว

      AGT is working to facilitate the fastest possible progression of AGT103-T, but it is not possible to predict availability yet. For more information: www.knowledgebase.americangene.com/when-will-agt103-t-be-available-for-use

  • @natashathenurseful
    @natashathenurseful 3 ปีที่แล้ว +2

    . How great it would be to have a cure for cancer. Especially ovarian and lung cancer.

  • @violetmcgilp9939
    @violetmcgilp9939 3 ปีที่แล้ว +1

    How long till cancer vaccine ?

  • @nunyab1836
    @nunyab1836 3 ปีที่แล้ว

    how do we invest in your company???

  • @stanleyogbolu861
    @stanleyogbolu861 3 ปีที่แล้ว

    I would love to follow up on your progress, what are the avenues

    • @AmericanGeneTechnologies
      @AmericanGeneTechnologies  2 ปีที่แล้ว

      To stay up to date, connect with us on social media or visit our web site and sign up for our newsletter. For more information:www.knowledgebase.americangene.com/how-can-people-from-africa-participate-in-the-trials

  • @akhilbabupasupuleti7534
    @akhilbabupasupuleti7534 3 ปีที่แล้ว +1

    Hii sir, by which yr we expect a permanent cure for hiv

    • @antoniostorcke
      @antoniostorcke 3 ปีที่แล้ว +2

      The answer is 2021. AGT is on the cusp. Vaccines will follow.

    • @AmericanGeneTechnologies
      @AmericanGeneTechnologies  2 ปีที่แล้ว

      AGT is working to facilitate the fastest possible progression of AGT103-T, but it is not possible to predict availability yet. For more information: www.knowledgebase.americangene.com/when-will-agt103-t-be-available-for-use

  • @bedamapunda143
    @bedamapunda143 3 ปีที่แล้ว +4

    Oh oh Jehoval God bless you

  • @MariaSantos-ww9fl
    @MariaSantos-ww9fl 3 ปีที่แล้ว +2

    Parabéns que tudo está dando certo # Deus abençoe a América...

  • @Liberty309
    @Liberty309 3 ปีที่แล้ว +2

    Next you need to fix the liver so it can start synthesizing our own vitamin C

  • @natashathenurseful
    @natashathenurseful 3 ปีที่แล้ว

    Sounds like the idea used for covid vaccine. Interesting.

  • @pitoupitou8438
    @pitoupitou8438 3 ปีที่แล้ว +2

    do it fast people live in the world will consider you first great hospital in USA and your country will get power of,love from people poor ,and make it before some country make first then u