Great explanation Sir, Would it be possible for you to make more videos on alkylation, acylation, adol reactions, beta elimination and related rxns, heterocyclic synthesis and reactivity Pleaseee They way you explain is very clear.
@@asmaakram250 yes thank you, I was able to understand perfectly, a stronger acid can replace a weaker acid only in this reaction they are using HCl and I wanted to know if sulfuric acid a weaker acid can be used instead of HCl not the other way around. So for instance I would be using sulfuric acid to form the ketone. I think it can be used instead only it would require a larger quantity of sulfuric acid over HCl I presume
yes, and it actually would be better a stronger acid gives a better kinetic constant but be careful with the concentration of the sulfuric, in my experience, going over 70% chars the reagents (basically reduces all organic compounds to elemental carbon, which is not great)
@@ivantimofeev2233 I appreciate your comment, thank you for your input. The good thing is that the reaction takes place in an aqueous soln. and the sulfuric acid would be added slowly but I guess it would be best to pre-dilute the sulfuric acid before addition. I actually ended up trying sulfuric acid and it worked, it was performed at mg scale just as proof of concept and it worked great. Took quite a lot of sulfuric acid, I was surprised.
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this man has been carrying me through my major in college
What's your major?
This guy does better explanation than ph.d profesors, better examples than the online homework!
Thanks!
Thanks man. Been watching your vids for years now so again thank you.
Bless you
How'd it go!?
@@PunmasterSTP Bro asked 4 years later
@@aidentrindaderollno.4865 lol I’ve asked people 10 years later before, and some have gotten back to me 😆
this man knows everything under the sun
This might be basic of me to say, but thanks again for all these great videos!
this is a lifesaver
Great explanation Sir,
Would it be possible for you to make more videos on alkylation, acylation, adol reactions, beta elimination and related rxns, heterocyclic synthesis and reactivity
Pleaseee
They way you explain is very clear.
bless you, gotten ,me through both Ochems!
Thanks for extras🙏🙏....it helped to understand better
Sir Why ethoxide ion not attack Alpha corbon in in the first reaction?
Thank you for all your videos
Thank you once again.
great explanation sir!!!
thank you man appreciate it
You are the best for me
why hydroxide can attack carbon directly but not when it was Eto? (Eto attacked alpha hydrogen first)
Because Eto is not sterically hindrance so it will not added to carbonyl group at first
Thanks
Will the Ester part hydrolyse into alcohol if we have 2eq of hcl?
Hello, can you please explain perkin condensation too?
why does it attack the alpha-hydrogen only?
And also, why ethoxide is a good leaving group?
EtO- is weak base and also there is no other better leaving group than EtO-
Thanks upload daily for neet ug 2019
Can you make a video on perkin's Condensation,Please.
why the LDA didn't react directly with carbonyl carbon at first but it react first with alpha hydrogen?
LDA isn't nucleophilic
Because Acid -base rxn happens at a very faster rate. Then Nu attack
Can HCL be substituted with sulfuric acid?
@@asmaakram250 yes thank you, I was able to understand perfectly, a stronger acid can replace a weaker acid only in this reaction they are using HCl and I wanted to know if sulfuric acid a weaker acid can be used instead of HCl not the other way around. So for instance I would be using sulfuric acid to form the ketone.
I think it can be used instead only it would require a larger quantity of sulfuric acid over HCl I presume
yes, and it actually would be better
a stronger acid gives a better kinetic constant
but be careful with the concentration of the sulfuric, in my experience, going over 70% chars the reagents (basically reduces all organic compounds to elemental carbon, which is not great)
@@ivantimofeev2233 I appreciate your comment, thank you for your input.
The good thing is that the reaction takes place in an aqueous soln. and the sulfuric acid would be added slowly but I guess it would be best to pre-dilute the sulfuric acid before addition.
I actually ended up trying sulfuric acid and it worked, it was performed at mg scale just as proof of concept and it worked great. Took quite a lot of sulfuric acid, I was surprised.
Why does it needs to match?
Awesome
thanks
Organic chem is my major and reaction mechanism is my worst nightmare pls help me
Interesting
Nice
🎉
bless you
Bless u
Lol