May be following issues with the synthesis Scheme-1: Methyl amine will give a mixture of tertiary amine and a secondary amine. Scheme-2: Friedal craft alkylation will give ortho substituted product as OH is ortho-directing group
Sir route one is wrong because oh is electron donating group and chloro acetyl cholride is electron withdrawing so It attack on ortho and para position not on meta
u r wrong in route 2, u r saying that first product in route 2 is chloro phenyl acetonitrile. where the nitrile group is present. u r wrong. pls make necessary correction
Very useful thank you sir love from tamilnadu ❤️
May be following issues with the synthesis
Scheme-1: Methyl amine will give a mixture of tertiary amine and a secondary amine.
Scheme-2: Friedal craft alkylation will give ortho substituted product as OH is ortho-directing group
Mujhe bhi yahi doubt hai
Sir ne to concussion main daal diya
Sir aap sahi bole but its friedel crafts acylation not alkylation
@@palshah3509 doesn't effect much infact acyl or bhi acha group hai alkyl se
Sir koi +ve charge phenol par attack karega to wo ortho Or para par ataach karna chaiye
But apne meta par attach karva rakha hai
Aisa kyu
Phenol shows ortho para electrophilic substitution.. So why you use phenol as a meta detector in route 2...??
Bhai mujhe bhi yehi doubt hai
Clear ho jaye to mujhe to bataito
Product form. Is in very minnor amount bro and these route is totally wrong
Your classes awesome sir.. tq so much sir.
The hydroxy group of phenol allows the chloro acetyl group to ortho or para not meta during acetylation
Sir phenylephrine me ortho meta para position ke bare me bta dijiye if alkyl chain meta position par h to OH gp. To donate gp. H.
Sir route one is wrong because oh is electron donating group and chloro acetyl cholride is electron withdrawing so
It attack on ortho and para position not on meta
Sir could i write 1 synthesis means route 1 in Semister exam.... Is it ok??
Sir phenol is ortho para directing then why positive attack on meta position?plz clear my doubt sir
Mera bhi yahi doubt hai
Clear ho jaye to mujhe bhi btana
sir please tell which books you follow
jo bi drugs ki synthesis krbayi hain apna kya vo sabhi thik hain galat toh nhi hain ya
Sir'can u make the video of all the importan drugs which is beneficial for gpat exam.plz sir
Sure
Definitely, your GDC classes and features are awesome. Great works sir. I admire your works sir.
Synthesis of Diazepam .plz plz as benzodiazepen is an important drug class.
Soon we will post
Today we will upload
iot means kya hai
Route 2 is wrong its clearly friedal crafts acylation and OH is a ortho para directing group
Sir will all theese video are helpful for Pharmacist exam also
Ya you can refer it, but in competitive exam main synthetic has been asked
Like sir what compound they may ask??
Protype drug like diazepam etc.
Sir aap b pharma 4 semester ki all drug synthesis ki video banaiye sir please 😊😊😊😊😊 Thanq very much
Kindly visit play store all Synthesis already are there.
All important drug for medicinal chemistry make video
We were working on it soon you will get more and more videos
Sir look so young ❤
Thank you so much sir 😇😇😇😇
Please do video on starting materials for synthesis of different drugs with pneumonics plzzzz
Sure we will do it soon.
Thank you fr ur support
Excellent
Thxx sir.... Love u
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Very useful
Thank you...your every comment motivates us to more better in future.
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u r wrong in route 2, u r saying that first product in route 2 is chloro phenyl acetonitrile. where the nitrile group is present. u r wrong. pls make necessary correction
Thank you sir
Sir please do 6th sem videos of medicinal chemistry
Soon we are posting all videos, up to 15th March u will get all videos.
Synthesis of non selective cox inhibitors
Sure we will do
Thnxz sir
sir hindi m bhi batao
Thank you sir