Zinc finger motif

[@akhilraaj]

I’m a doctor and I come across your videos all the time on various topics but never watched them because I never thought your videos will cover them comprehensively. Damn boy I was wrong, you are really good.

[@shomusbiologyofficial]

It's a pleasure to know that you liked my lectures

[@chriplip5283]

Brilliant and concise, helped me understand quickly. thank you bro 🙏

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@mridhusharma9907]

Sir, I like ur other videos but I am sry this did not go well with me. It seems to crude. Some important information was missing like it binds in major groove and contacts three bp, It's binding with cys and his, etc

[@ivankuzko7037]

Thank you so much from 1 faculty of medicine of Charles university in Prague!)))

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@VicbengtPL]

Love your videos brother, you are doing a great job! Thanks!

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@nothingggg656]

Thankyou so much sir👍🏻♥️

[@shomusbiologyofficial]

You're welcome

[@drnamsoon]

Thank you so much i am here just for concept becz this is most repeated ospee of my tomorrow exam we will see if this question repeat again thanks 👍

[@shomusbiologyofficial]

All the best for future career

[@georgiacohoon2513]

this was so useful! thank you so much :)

[@shomusbiologyofficial]

You're welcome

[@tutku535693]

Thanks for your all worthy efforts, i established every part of information you explained along the video clearly, well appreciated :)

[@misstaniamaryam]

Brilliant, thank you for making it easy to understand!

[@shomusbiologyofficial]

You're welcome

[@muhammedyousafk4115]

Thankyou sir❤

[@shomusbiologyofficial]

You're welcome

[@attulurivenkatabadarinath1044]

Nice explanation, good

[@dipteshking]

helpful video , but please provide complete information about the topic before giving the applications (where can be used) i hope applications we think of right at that moment . you have not described the structure neither said anything about 2cys and 2his. its just a suggestion please dont take it otherwise. thank you

[@ayaqz3144]

thank you man

[@shomusbiologyofficial]

You're welcome

[@chanchalkumari2503]

Nice explanation

[@-_-ok9550]

thankyouuu

[@shomusbiologyofficial]

You're welcome

[@samrakhan4408]

This helped so much!

[@anag2749]

you're a great descriptor .Thanks

[@shomusbiologyofficial]

+Ana G you're welcome

[@johntindell9591]

Thanks a lot.

[@shomusbiologyofficial]

You're welcome

[@kainatrehman7384]

Thanku soo much sir.. Plz make a video on targeted drug delivery on mice models against cancer...plz

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@akshayavidhya9325]

thanks sir

[@mshisha]

Thank you

[@rajeshnaik9346]

thanks

[@vitthal_donadkar]

This video was wonderful. it cleared many basic concept.
thank u sir....
sir plz make video on "Fermentation kinetics"

[@JuhiMittal]

ty so much

[@didier4529]

Bright man

[@ayezabhat5026]

thanku

[@shomusbiologyofficial]

You're welcome

[@salmanzaibkhan7457]

Is there any lecture of talens?

[@knowledgejunction1643]

Niceeeeee👍👍👍

[@kolhapurkarpatil]

More details one can get in pathfinder

[@beautydutta2034]

Can you tell me the chapter name in pathfinder book

[@himanshunainwal8939]

@@beautydutta2034 161 page number from second book...

[@beautydutta2034]

@@himanshunainwal8939 sorry I didn't got zn finger here ..it will be better if you say the chapter

[@himanshunainwal8939]

@@beautydutta2034 molecular genetics -- after eukaryotic transcription

[@beautydutta2034]

@@himanshunainwal8939 finally got.. thanks for your response

[@ajaydastp3304]

sir please conduct a class about protein domains and motifs separately

[@shomusbiologyofficial]

It's already there in my channel

[@red8527]

So...I have heard the term Zinc Finger Nuclease.
That should be a nuclease enzyme with a zinc finger motif which we can artificially modify so that it attaches to a specific region on the gene & makes a cut??

[@thejjm59]

I love you

[@Brighterworld5827]

Sir fos and Jun have zn binding domain ??

[@richadas171]

Zinc finger nuclease and zinc finger motif...are they same??

[@doaaaldabibaaa9200]

I really love u

[@shomusbiologyofficial]

Thank you

[@rishimaborah9956]

Sir, can you please upload videos of zinc finger nucleases and TALENS as well?

[@rishimaborah9956]

It will be quite helpful! Since there are less videos in this topics. Thank you.

[@shomusbiologyofficial]

Coming soon

[@rishimaborah9956]

@@shomusbiologyofficial Thanks!

[@triptimehra5940]

how does the fusion protein helps in regulating the transcription process ?

[@TheIncredibleChowdhury]

You are a life saver dude... :)

[@biologicalresearch5836]

There is no alternative of yours on TH-cam

[@ananyabanerjee4758]

please do a class on TALEN

[@shomusbiologyofficial]

Yes I will do that soon

[@vermasona2820]

Sir, transcription start when polymerase enzyme bind to tha promotr site .so in these case we dont required poymerase enzyme? Plz tell me because i'm confused about this😔

[@AlisonFujii14]

Why does the histidine and the cysteine associate with the zinc? Wouldn't those side chains not want to be near a positively charged ion like Zn2+?

[@dsev13]

My guess would be that histidine and cysteine are uncharged at neutral pH and are Lewis Bases, meaning they have an extra lone pair of electrons, and since the bond with Zn in these kinds of organometallic bonds are usually coordinate covalent, Zn requires an electron donor.

[@debadattapanda5829]

Sir, what is the signifucance of fusion protein in this & does this mean that we can modify it

[@surendraprasadsah7026]

A lot of info is missing

[@kumarpolimera9565]

How can we modify the Zn finger n how can we add that to a biological system sir

[@mehreensaigal4343]

Please make a series of protein-dna interaction and methods :)

[@shomusbiologyofficial]

Okay

[@imrocknreeling]

Zink

[@mahadehassan5072]

can i get bacterial motif please

[@the_explorer_anje8243]

Sir plz do not repeat same things and you could add more info

[@MultiSim89]

U sir are the man lol

[@debashishadhikary9030]

Probably. Due to zinc finger transcription I went bald all over body i.e. alopecia Universalis.

[@cerenesen7776]

turkish translate please!!!!!!!!!!!

[@marlonmillard4277]

zn 2+

[@yusufates885]

Tuuutori yal lol

[@trexsbp409]

Amateur

[@WilldabeastFTW]

bad