Vitamin B3 Niacin Deficiency (Pellagra) | Sources, Causes, Symptoms, Diagnosis, Treatment

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  • เผยแพร่เมื่อ 5 ก.ย. 2024

ความคิดเห็น • 86

  • @jjmedicine
    @jjmedicine  4 ปีที่แล้ว +30

    **PLEASE NOTE THE FOLLOWING ERRORS:**
    1) When I said NADP is generated in the pentose phosphate pathway, I meant to say "NADPH" is generated in the pentose phosphate pathway.
    2) Pellagra is a condition CAUSED BY NIACIN DEFICIENCY, not necessarily another term for Niacin deficiency
    ***Sorry for the confusion***

    • @user-mr3iv7bj6n
      @user-mr3iv7bj6n 3 ปีที่แล้ว +2

      ur great dr continue ur explination is amazing

    • @rashikasingh7607
      @rashikasingh7607 3 ปีที่แล้ว +2

      In Pentose phosphate pathway NADPH reduced to NADP+

    • @Hyper-Linkman
      @Hyper-Linkman 6 หลายเดือนก่อน

      Should also mention that saying "vegan diet" as a blanket term is incredibly thick-headed, and only serves to further the stereotype that a vegan diet is nutritionally inadequate, whereas those of us who have done our homework know better 😉
      Edit: Just caught that you at least added a caveat to your statement. WFPB diets can lead to optimal nutrition when done properly, and we're still waiting for the inevitable death rattle of the keto/carnivore camp. The age of bro science is slowly coming to an end.

  • @ranicefreire2611
    @ranicefreire2611 3 ปีที่แล้ว +37

    Recommended daily dose are away to low...only see benefits with much higher dose

    • @glodusmuspell9069
      @glodusmuspell9069 3 ปีที่แล้ว +1

      How much?

    • @ranicefreire2611
      @ranicefreire2611 3 ปีที่แล้ว +11

      @@glodusmuspell9069 its all depends for what you need, for high blood pressure 500mg,depression ,bipolar,esquizofrenia can be from 1000mg to even higher then 2000mg

    • @ranicefreire2611
      @ranicefreire2611 3 ปีที่แล้ว +16

      I read an article about CoQ10 can treat bipolar in 90 % to 100% of the time. Doses of 200mg and up. Seizure that dont respond well with treatment could be a B6 dependent dose. If your health issues NOT caused by parasites, then for sure can be some type of deficiency or many deficiencies ( parasites can also cause deficiency). Be your own Dr, investigate your issues...if it is deficiency, investigate the cause of the deficiency ( dont treat just the deficiency only).

    • @lloydpalmer5735
      @lloydpalmer5735 ปีที่แล้ว

      Ok

    • @Pcristina789
      @Pcristina789 10 หลายเดือนก่อน +2

      Yes that’s true - I have major depression with psychosis and I am taking 1000mg niacin per day night time and my psychosis improved so much, almost no symptoms: I am reading “Niacin the real story” by doctor Hoffer , Dr Saul and dr Foster. I tried to say to my psychiatrist but he doesn’t believe in it. Always is good to do blood work and check with the family Doctor everything.

  • @tiktac2160
    @tiktac2160 3 ปีที่แล้ว +20

    This video has saved me. Thank you!!

    • @billybrownnaoussi5599
      @billybrownnaoussi5599 3 ปีที่แล้ว +1

      How? can you share with us please.

    • @aztecgaming7287
      @aztecgaming7287 2 ปีที่แล้ว +2

      Yes plz explain

    • @pramujisinggihriyanto6901
      @pramujisinggihriyanto6901 ปีที่แล้ว +3

      I got dermatitis in my hand n food due to sun light sensitivity. I go to doctor but she didnt tell about B3 deficiency.
      From TH-cam channel (dr. Eric Berg and others), I got to know that I need Niacin. I bought Niacin from online shop (Tokopedia), and fantastically, I get recovered from dermatitis.

  • @Psychiatry.321
    @Psychiatry.321 9 หลายเดือนก่อน +4

    Most symptoms are identical to Schizophrenia, even some schizophrenic patients does not flush even after taking 5,000 mg daily of Niacin (Nicotinic Acid).

    • @KBB-nf1dr
      @KBB-nf1dr หลายเดือนก่อน

      No one should be taking Nicotinic Acid it’s Synthetic coal tar, the reason people are deficient in these B vitamins is because when they are subjected to the synthetic form, like in fortified foods or these fake vitamins, it damages the receptor, and they cannot absorb the real B vitamin
      If you want to supplement you’d be better off, taking tryptophan or Niacinimide Nicotinamide with equal dosages of TMG
      Avoid Nicotinic Acid & Niacin like the plague & ALL Fortified foods

  • @Kittiesanddragons
    @Kittiesanddragons 4 ปีที่แล้ว +26

    So this one time i was asked a question of 4Ds of Pellagra, i told Dementia, Diarrhoea and Dermatitis but couldn’t remember the 4th. The teacher looked me dead in the eyes and said Death. Lmao that cracked me up

  • @anny31
    @anny31 3 ปีที่แล้ว +8

    Love the lessons..
    My friend has the red irritated hands up to the wrist.. like wearing red bumpy looking gloves.. happens every early fall through late spring
    So strange.. she doesnt have the other symptoms unless its super mild

    • @heidimisfeldt5685
      @heidimisfeldt5685 3 ปีที่แล้ว +2

      😎💖 Just share a few pellagra tutorials with her, maybe watch it together. But I would do it in a friendly way, like sharing something really interesting.
      Some videos show the pictures and she might recognize her condition by watching. Works better then talking about it. Some folks just don't like to be told what to do, so showing the evidence has better results. Let her do the thinking without pointing out the obvious to your friend.
      Add some niacin rich foods to snack on, and she will remember.

  • @JR-zm2yu
    @JR-zm2yu 3 ปีที่แล้ว +7

    Very informative, thank you.👍👍💜

  • @RS-pu9ti
    @RS-pu9ti 3 ปีที่แล้ว +13

    Very well explained, thank you for sharing ✌️

  • @SkedgySky
    @SkedgySky ปีที่แล้ว +2

    I get a mild flush starting at 50mg. ... A crushed tablet = super fast absorption. Usually a hot tingly sensation around my lower face, is my first sign. Very interesting.

  • @ilciavargas7318
    @ilciavargas7318 2 ปีที่แล้ว +8

    Interesting video! yes legumes also contribute to our good health as legumes provide vitamins, minerals and legumes ocxigenate the blood given a lot of energy to people. I consume legumes 5 times per week. I keep slim and I do have so much energy just like a young person¿ we are what we eat so this is why I have a natural food! No sugar, not frying food, no proced food and no sugary drinks, just water and home made food. You can make a pot of legumes that will last 4 days without been frozen and warm up in the cooker no in the microwave.

    • @savydude1
      @savydude1 ปีที่แล้ว +1

      Legumes also have lectins!

  • @pramujisinggihriyanto6901
    @pramujisinggihriyanto6901 ปีที่แล้ว +2

    Very helpful information.
    Many thanks, Dude

  • @CyrilAndPriscilla
    @CyrilAndPriscilla 7 หลายเดือนก่อน

    Hepatic synthesis also requires B6, not just riboflavin.

  • @thokalaramesh4883
    @thokalaramesh4883 3 ปีที่แล้ว +2

    Tq , i understood about the pellagra disease and wt is NADPH

  • @Happy-jv9fd
    @Happy-jv9fd 2 ปีที่แล้ว +3

    Can you use Niacinamide orally in the powder formula ?

  • @karunasree8476
    @karunasree8476 3 ปีที่แล้ว +2

    It helped but
    If given % of b3 in food items it is more helpfull good thanks

  • @kh2945
    @kh2945 2 ปีที่แล้ว +5

    Niacin supplements in high doses ( capsules and tablets )may induce insulin resistance !

  • @hvvijuka
    @hvvijuka 2 ปีที่แล้ว +4

    hi Doc, hypothyroid people do not flush when they take immediate release niacin, what's the reason?

    • @cosmichealth3907
      @cosmichealth3907 2 ปีที่แล้ว +4

      Dose could be one of the reason..
      Hypo people may havee compromised liver and niacin not getting metabolised does not cause flush...higher dose may be needed

    • @rosyc9250
      @rosyc9250 2 ปีที่แล้ว

      Low omega 3 can induce an inflammatory response that can lead to autoimmune diseases such as hypothyroidism. Omega 3 will decrease the threshold for niacin flush.

    • @The_New_Abnormal_World_Order
      @The_New_Abnormal_World_Order ปีที่แล้ว

      I do!

  • @ibadullahtahir7541
    @ibadullahtahir7541 4 ปีที่แล้ว +3

    thanks jj medicine it reallly helped me to understand this concept
    \

  • @gregorykarimian3813
    @gregorykarimian3813 3 ปีที่แล้ว +10

    Tryptophan makes quinolinic acid which makes nad. Tryptophan does not make niacin.
    And let me add by saying why this is important. It’s because isoniazid inhibit the production of b3 via the tryptophan pathway. That is why you can supplement the patient with niacin because they’re two different pathways.

    • @yorkierussell9255
      @yorkierussell9255 ปีที่แล้ว

      He was just saying that tryptophan makes NAD, which is true. There may be intermediate steps to get to NAD, but the most important thing to know is that tryptophan is used to make NAD. The other details in the pathway in the middle aren’t important. What you said in the 2nd paragraph is correct, but isoniazid inhibiting B3 production via the tryptophan pathway has nothing to do with the unimportant detail of knowing the intermediate steps. You can learn that if you want just for “fun”, but it’s not important. Focus on the big picture.

  • @stellabrown909
    @stellabrown909 2 ปีที่แล้ว +1

    Thank you so much for the information

  • @nitinnaik833
    @nitinnaik833 ปีที่แล้ว

    Property explained. Please share the prescription drug name

  • @FisherKot11235
    @FisherKot11235 2 ปีที่แล้ว +2

    I take 3,000mg of niacin a day. I love the flush. I’ll never stop

    • @DaKeezl
      @DaKeezl 2 ปีที่แล้ว

      Okay, but what for?

    • @normcochran9414
      @normcochran9414 ปีที่แล้ว

      He just told you lol for the flush.

    • @arielharbour1095
      @arielharbour1095 ปีที่แล้ว +1

      What do you find you love about it?

    • @lauren489219
      @lauren489219 ปีที่แล้ว +1

      What has it helped you with?

  • @yuvrajsharma1179
    @yuvrajsharma1179 4 ปีที่แล้ว +3

    It helped a lot, Sir

  • @kavinkumar6965
    @kavinkumar6965 2 ปีที่แล้ว

    Can I eat vitamin b3 rich foods to cure my acne and pores

  • @adoonkiialle8646
    @adoonkiialle8646 2 ปีที่แล้ว +1

    Thank you so much j j

  • @letmeintoyoursoul
    @letmeintoyoursoul 3 ปีที่แล้ว +7

    Vegan diets are not innately an issue if properly balanced and centered around eating whole foods . Malnutrition is the issue because you can eat an inadequate omnivorous diet and run into a B3 deficiency. I think isolating certain vegan diets creates a sense that this diet is more prone to this deficiency when the matter at hand is just poor nutrient intake of niacin. Furthermore if one is eating a variety of grains, legumes and fruit then they should be able to easily meet their needs even with men who have a slightly higher RDA of 16 mg/day.

  • @majesticbutterfly
    @majesticbutterfly ปีที่แล้ว

    Can someone with a fatty liver take niacin without making the liver worst???😮

    • @nameofthegame9664
      @nameofthegame9664 10 หลายเดือนก่อน +2

      yes it would in fact be advisable to take a niacin supplement when you have a fatty liver.

  • @joltjolt5060
    @joltjolt5060 2 ปีที่แล้ว +2

    My dog might have had pellagra? Is dog food that bad?

  • @haico4597
    @haico4597 ปีที่แล้ว

    Mọi người hãy ăn hong cho cô nhiều duc khỏe và để nâng cao sức khie cho bạn ca gia dinh cua ban trai cay các loại đậu và rau qua và bắp. Khoái làng và tôm các.thi thoảng ăn và uống nước nhiều buổi sang và tiếp cho bạn được nhiều duc khoe cam ơn các ban

  • @mohamedfaayad3037
    @mohamedfaayad3037 4 ปีที่แล้ว

    Like before watching the video

  • @medicalbiochemistry_
    @medicalbiochemistry_ 4 ปีที่แล้ว

    Nice

  • @PinkFlowers365
    @PinkFlowers365 ปีที่แล้ว

    ty

  • @glodusmuspell9069
    @glodusmuspell9069 3 ปีที่แล้ว

    In my B50 complex there is 50 mg of niacinamide. Is it okay to take it everyday? Is 50 mg niacinamide too much?

    • @alexrivera4602
      @alexrivera4602 3 ปีที่แล้ว +3

      Yes, you can easily even take 2000 miligrams. My friend is taking 2500 for her acne and it’s gone she just takes it now to keep it at bay. It’s very safe, you’ll throw up before you ever get to poisoning levels

    • @cosmichealth3907
      @cosmichealth3907 2 ปีที่แล้ว +4

      Depends on condition you are using. Naicinamide does not work on lipids...does not cause flush
      For skin the best form is free niacin...flush means vasodilation ,which improves skin..improves l lipid levels

  • @shaneblack8082
    @shaneblack8082 8 หลายเดือนก่อน

    Vegemite.

  • @elizabethmears5816
    @elizabethmears5816 3 หลายเดือนก่อน

    Four D's and one green apple.

  • @dailydoseofmedicinee
    @dailydoseofmedicinee 4 ปีที่แล้ว +14

    Niacin Deficiency Symptoms
    👍
    thick, scaly pigmented rash on skin exposed to sunlight.
    swollen mouth and bright red tongue.
    vomiting and diarrhea.
    headache.
    apathy.
    fatigue.
    depression.
    disorientation.

    • @rashikasingh7607
      @rashikasingh7607 3 ปีที่แล้ว +1

      3 Ds -Dermatitis,Diarrhoea,Dermentia.

    • @lavheejoycecallao1553
      @lavheejoycecallao1553 2 ปีที่แล้ว

      Hi does taking nicotinamide affect the skin ? Like it make you breakout?

  • @danielrodgers3002
    @danielrodgers3002 3 ปีที่แล้ว +6

    Wrong in the first 10 seconds. Niacin and Nicotinamide are not the same thing. Please remove this video until you can provide accurate information. Thanks

    • @user-mr3iv7bj6n
      @user-mr3iv7bj6n 3 ปีที่แล้ว

      whats the different i think they are same

    • @fortiktokuse9803
      @fortiktokuse9803 2 ปีที่แล้ว

      @@user-mr3iv7bj6n Niasin have an acid group while nicotineamide have Amide group Nh³

    • @cosmichealth3907
      @cosmichealth3907 2 ปีที่แล้ว +1

      Both are different...
      But what works on humans is free niacin...
      Should always use free niacin with limited dose and gradually increase

  • @LuvLight44
    @LuvLight44 2 ปีที่แล้ว

    Why is Africa always emphasized because Y’all will be next coming over to America y’all get on my damn nerves with that mess quit calling that Black People are the face of the pandemic is y’all that start the damn