By God, the Most High, the Great, you, professor, deserve millions of likes because of this great explanation, the idea of which thousands of teachers were unable to convey.
I was struggling horribly with this concept. Never have I felt more able to learn a concept that I have taken hours and hours looking into previously than this. Now every monosaccharide seems to be a breeze when converting to the Haworth projection! Thank you!
@@wondersofchemistry Thank you. I also spent hours looking at my lecture slides only to be able to do all the examples on your video after you explained the concept before you showed the answers to the problems. You did an absolutely fantastic job explaining it, and thank you for uploading this and helping hundreds of thousands of people!
totally I agree. and no smart talk like other videos try to make chem sounds so complex and enjoy audience suffering something only they know better or explain the unnecessary. this one just facts right to the points and critical clarification that test taker needs to know.
I was getting confused in these structures even after studying 'em 3 times from my biology textbook (Chapter Biomolecules)......after watching ur easy and awesome explanations I won't forget them anytime soon!! Thanks a lot Sir!!
i’ve been watching videos on this all afternoon long but i knew when i saw yours that this was the one haha. thank you for explaining details that are often left out, such as what atoms change their places during the switch to the cyclic form and with what motivation, why it has to be the fifth carbon atom reacting with c1 and why on earth the substitutes on the left have to go on top. will be sending this to all the chem students in my hear. thanks for making this
Before ,I used to choose videos based on views and subscription . But this tutorial changed the way of my perception . Crystal clear about this topic . Thank you for teaching with minute details . Subscribed !!
Holy smokes. This is one of the best, if not the best, video i've seen. It made me understand so well, and it answered all my questions. Thank you so much.
I’m at last high school class in Poland. That topic was one of the most important for me and i always had trouble to learn it. After i watched this video i urserstood everything. Thanks a lot!!
I think this is the best video for understanding fisher's and hawarth's projection. After reading many books and papers now finally I'm able to understand this topic because of this wonderful vdo...
This was an excellent and concise explanation on a topic I was really struggling with. I was able to take this lesson and apply it to the cyclization of ketoses, too. Thanks!
Thank you so much for sharing your knowledge! Your videos are very clear and easy to follow. Along the way you seem to have a knack for answering questions that might be asked. Very enjoyable. After going back a few times, I was able to pass your final quiz. I look forward to watching the rest of your content! Subscribed!
The presentation of the information was spectacular! The drawing and animation were some of the best I've seen on TH-cam. Will be definitely looking into your other videos, keep it up!
Thankiess for this. I feel so confused when my teacher taught this in class. But with this video, I now understand the topic and I feel so proud with myself.
Thanks Teresa. Do you have any other suggestions on what you believe you and your fellow students could benefit from within the realm of biochmistry that i have not already covered on my chanel? Maybe have a chat to your fellow students as well to see what they are struggling with? Regards, Wonders of Chemistry
Thank you so much! I was looking at my class's powerpoint slides since I typically fall asleep in class and was mega confused. You saved my final exam I think/hope.
This has been such an helpful video! I finally understood what substituents to look at when determining whether they are on the same side or the opposite side of the ring. One caveat I would have though, is alpha is on the SAME side, while beta sugar is on OPPOSITE side. I think the video might have reversed the two
no worries, its great to hear that my video is assisting you with your preparation for entry into university based education. Good luck with it all. Regards, Wonders of Chemistry.
Brillant Video made the concept crystal clear. I was struggling with the structure of L Beta Galactopyranose as I was just remembering that if the OH is down then it is alpha. It worked until I met with L structures. Your point about the look at c6 and the anomeric carbon is Brilliant. This made it so much easier. I literally can't stress enough how mindblowing this video is Thank you man really thank you so much.
Hi Nate. Its been a while since i have looked at my youtube channel. What a lovely comment.Thank you so much. I might just start making more videos thanks to you. Regards, MG
You literally saved my life with this video, thank you so much !!! In this quarantine i am all by myself with my schoolstuff but this really helped me !! 👏🏻👏🏻👌🏼👍🏻🔥
thank you so much for this video, this made me understand the concept more and also understand fully well how different fisher and haworth projections. You saved my grades! More power and Godbless!
Thanks Denise. How exactly did the video help you in your understanding? Just keen to know which segments of the video you found to be of most benefit. This will help me in how i create my future videos. Thank you :-)
Hi! It helped me understand how the structure was formed because you taught it step by step, and also how the different atoms interact with each other 😊
THANK YOU SO MUCH! i have my orgo final today and my professor didn't really explain how to do this, so thank you for easing my stress about this topic :)
oh thank god bless you honestly.. i wasn't even studying chemistry this showed up in my biomolecules unit in bio and the alpha and beta glucose ring structures were bothering me so bad i had to make sense of it before i moved on... thank you!!!!!🙏
Amazing video! At around 6:00 however, the H+ does not attack, there is a proton transfer but the lone pair on the oxygen should attack the hydrogen in the end. Thank you so much! I have trouble with stereochem because it gets messy and I had trouble drawing structures in Haworth fashion but I have no trouble now!
How do you know if the #5OH group is going to be pointing up or down to form the alpha or beta anomer from the Fischer projection? I can make the Haworth, but it seems to me every fischer projection in this video has been with the #5OH pointing down, so I don't know how to make anything other than the alpha anomer.
Hi Andrew, recall that objective of the OH functional group located on carbon number 5 of the fischer projection it to react and form an intramolecular bond with the aldehyde functional group located on carbon number 1. It is therefore non-existant after the formation of the cyclic structure and therefore has no bearing on whether the newly formed haworth structure is alpha or beta. What you should be focusing on is the relative positions of the CH2OH located on carbon 5 (cyclic structure) and newly formed OH on the anomeric carbon formed on carbon 1 (cyclic structure). If they are opposite sides of the ring (i.e., one facing up while the other is facing down) then you would be looking at the alpha anomer. On the other hand they are on the same side of the ring (both facing up or both facing down) then this would be the beta anomer. Feel free to contact me if you are still struggling with this. Regards, MG :-)
Great.. thanks... I was confused in open chain chiaral No 5. here how OH becomes O and how vanished H. Now I'm clear. Because of rotation it happens nicely 🙂. Thank you, sir.
Are all saccharides has the same cyclic structure regarding on the position of oxygen between carbon 1 and 5? Could it be possible that the other functional groups will be attach to other carbon group (2, 3, 4)?
It depends on whether it would be thermodynamically stable or not. For example fructose forms a ring structure between C2 and C5 as opposed to C1 and C5. This gives a 5 membered ring structure as opposed to a 6 membered ring structure.
Hi tysm this was super helpful. I'm still a little confused in assigning priorities in order to distinguish between the L and D galactose. I don't see how the carbon 6 has a lower priority than the carbon 4 molecule. Would you please be able to elaborate on that. I hope this doesn't sound confusing lol
I think there is a bit of a misleading explanation at 6:09. The H+ ion doesn't attack the O- from the former carbonyl. It has no electrons with which to perform such an attack. The electrons from the O- are what act as the base in this step, which is essentially just an intramolecular proton transfer. I know a lot of biochem/ochem professors will count off if you draw curved arrows in the wrong direction, so thought I'd mention this.
By God, the Most High, the Great, you, professor, deserve millions of likes because of this great explanation, the idea of which thousands of teachers were unable to convey.
I was struggling horribly with this concept. Never have I felt more able to learn a concept that I have taken hours and hours looking into previously than this. Now every monosaccharide seems to be a breeze when converting to the Haworth projection! Thank you!
Thanks Ben 🙂
@@wondersofchemistry Thank you. I also spent hours looking at my lecture slides only to be able to do all the examples on your video after you explained the concept before you showed the answers to the problems. You did an absolutely fantastic job explaining it, and thank you for uploading this and helping hundreds of thousands of people!
totally the best video about Fischer and Haworth Projection currently available on youtube, thank you so much
thanks!
totally I agree. and no smart talk like other videos try to make chem sounds so complex and enjoy audience suffering something only they know better or explain the unnecessary. this one just facts right to the points and critical clarification that test taker needs to know.
Thank you
I was getting confused in these structures even after studying 'em 3 times from my biology textbook (Chapter Biomolecules)......after watching ur easy and awesome explanations I won't forget them anytime soon!! Thanks a lot Sir!!
Your comment made me choose this video ❤ Thanks
Liar
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@@faidatadepeju3502nIgGa 😢
Me also@@faidatadepeju3502
Where has this video been all my life!!! I need more of this in all subject areas. Thank you soooo much.
I could cry. I finally think I understand this idea. Thank you so much.
This is literally the best explanation of any topic to ever exist in all of humanity 🙏🙏😘
I struggled with Fisher to Haworth for the longest time and after watching this video I finally understand! Thank you soooooooo much!!!
i’ve been watching videos on this all afternoon long but i knew when i saw yours that this was the one haha. thank you for explaining details that are often left out, such as what atoms change their places during the switch to the cyclic form and with what motivation, why it has to be the fifth carbon atom reacting with c1 and why on earth the substitutes on the left have to go on top. will be sending this to all the chem students in my hear. thanks for making this
Hi Chiara, thank you so much for your positive comments. It means a great deal to me. Thanks once again!
Before ,I used to choose videos based on views and subscription . But this tutorial changed the way of my perception . Crystal clear about this topic . Thank you for teaching with minute details . Subscribed !!
Thank you for your positive comments. It means a great deal to me :-)
Give this man an award
Thanks Anuja. Your positive comments are much appreciated :-)
Holy smokes. This is one of the best, if not the best, video i've seen. It made me understand so well, and it answered all my questions. Thank you so much.
Thanks Sofia. What a lovely thing to say. It is much appreciated. Hope all is well on your side of the world. Regards, Wonders Of Chemistry :-)
this is the best explanation of converting fischer to haworth i have ever listened to. thank you so much!
I’m at last high school class in Poland. That topic was one of the most important for me and i always had trouble to learn it. After i watched this video i urserstood everything. Thanks a lot!!
Thank you for this video, it help me a lot to understand this.
no worries :-)
So well explained! Love the animations you used to showcase the reaction mechanism
Glad you liked it!
I think this is the best video for understanding fisher's and hawarth's projection.
After reading many books and papers now finally I'm able to understand this topic because of this wonderful vdo...
Glad it was helpful! and thanks for your positive comments :-)
This was an excellent and concise explanation on a topic I was really struggling with. I was able to take this lesson and apply it to the cyclization of ketoses, too. Thanks!
Thank you so much for sharing your knowledge! Your videos are very clear and easy to follow. Along the way you seem to have a knack for answering questions that might be asked. Very enjoyable. After going back a few times, I was able to pass your final quiz. I look forward to watching the rest of your content! Subscribed!
Thank you very much, Professor! Love from an Egyptian Pharmacy Student ❤❤
The presentation of the information was spectacular! The drawing and animation were some of the best I've seen on TH-cam. Will be definitely looking into your other videos, keep it up!
Wow, thank you!
Thankiess for this. I feel so confused when my teacher taught this in class. But with this video, I now understand the topic and I feel so proud with myself.
THIS VIDEO IS A LIFE SAVER!!!!! Thank you so much for making it easy to understand!!!!!!
Thank you! i'm a french student and it was exactly what i needed
Merci beaucoup. Je suis heureux que vous ayez trouvé ma vidéo utile. Salutations d'Australie!
Thanks a lot, now I understand much better after the clear explanation and examples!
Thank you for your teaching. Way better than on class
Thanks Teresa. Do you have any other suggestions on what you believe you and your fellow students could benefit from within the realm of biochmistry that i have not already covered on my chanel? Maybe have a chat to your fellow students as well to see what they are struggling with? Regards, Wonders of Chemistry
Thank you so much! I was looking at my class's powerpoint slides since I typically fall asleep in class and was mega confused. You saved my final exam I think/hope.
This was so helpful and simple once it clicks you cannot forget it Thank You!!!!
THANK YOU! Nowhere in my textbook did it make sense like it did here.
No worries Jake. Thats great that video helped so much!! Feel frre to share with your fellow students :-)
I can't describe your work qulification it is so legendly
Thank you!! That was such a kind gesture :-)
I have a very important exam of my life on 3rd October ( the Jee advanced) it can almost make life...
The video helped me a lot..
Love from India
This has been such an helpful video! I finally understood what substituents to look at when determining whether they are on the same side or the opposite side of the ring. One caveat I would have though, is alpha is on the SAME side, while beta sugar is on OPPOSITE side. I think the video might have reversed the two
Hello and thank you very much for this explanation, you were very precise and I understood everything! Thanks again, many greetings from Italy
Ciao Cristiano, grazie mille per il tuo messaggio. Sono felice di essere stato di aiuto. Saluti, dall'Australia :-)
this video is just perfect. God bless you, thank you so much for uploading on here such a clear explanation of this important part of biochem.
Great work sir , I am from INDIA , so helpful video , i was struggling with this stuff . But you made it very simple and clear .
Thanks Rahul. I am glad that you found it useful :-)
Thank you so much, the video was short and on point, it really saved me a lot of time since I am preparing for uni-entrances
no worries, its great to hear that my video is assisting you with your preparation for entry into university based education. Good luck with it all. Regards, Wonders of Chemistry.
SUPERB explanations!
Thank you for the explanation. it's really easy to understand by watching this video!
Thank you for your positive comments :-)
Brillant Video made the concept crystal clear. I was struggling with the structure of L Beta Galactopyranose as I was just remembering that if the OH is down then it is alpha. It worked until I met with L structures. Your point about the look at c6 and the anomeric carbon is Brilliant. This made it so much easier. I literally can't stress enough how mindblowing this video is Thank you man really thank you so much.
Hi Nate. Its been a while since i have looked at my youtube channel. What a lovely comment.Thank you so much. I might just start making more videos thanks to you. Regards, MG
You the one that explain every detail thanks!
So much easily explanation with 100% understanding
TH-cam should be the only school for learning quickly.
thumbs up :-)
You literally saved my life with this video, thank you so much !!! In this quarantine i am all by myself with my schoolstuff but this really helped me !! 👏🏻👏🏻👌🏼👍🏻🔥
Your welcome. Feel free to reach out if there is anything else that you think would be beneficial for a future presentation.
I've been struggling learning this concept ever since online class started. I'm so glad I was able to understand. 😭💕 Thank you so much
Thanks for the positive feedback. Comments like this motivate me to make more videos :-)
Happy to help!
thank you so much for this video, this made me understand the concept more and also understand fully well how different fisher and haworth projections. You saved my grades! More power and Godbless!
Glad it was helpful!
Great video! Surprised you don't have too many subscribers. You deserve a lot more!!
Thanks Antonio. Your channel looks pretty cool too. Regards, from Wonders of chemistry down under in Australia
Thank you for teaching this! I’ve been having a hard time with this for daaays😅
Thanks Denise. How exactly did the video help you in your understanding? Just keen to know which segments of the video you found to be of most benefit. This will help me in how i create my future videos. Thank you :-)
Hi! It helped me understand how the structure was formed because you taught it step by step, and also how the different atoms interact with each other 😊
very good video with the practise at the end. made it much easier to ensure I got the hang of the concept.
Thanks :-)
❤❤ superb presentation.... One of the best videos on the topic ❤❤
THANK YOU SO MUCH! i have my orgo final today and my professor didn't really explain how to do this, so thank you for easing my stress about this topic :)
It is my pleasure. I hope you exam goes well.
Wondersofchemistry It went great! Thank you so much(⌒▽⌒)
Thats great news! Well done!!
It’s such an easy-to-understand presentation. Thank you
Thanks for the feedback. I am happy that you found the video useful. Feel free to share with your fellow students :-)
oh thank god bless you honestly.. i wasn't even studying chemistry this showed up in my biomolecules unit in bio and the alpha and beta glucose ring structures were bothering me so bad i had to make sense of it before i moved on... thank you!!!!!🙏
u truly have a way with clearing all potential doubts a student could have before they could even think to pause and ask LOL
You made this extremely easily to understand thank you 🙏
thank you. this was helpful beyond measure. more power to you.
Thanks for the positive comments :-)
The only video that made me understand perfectly thank u
this is great. turn right 90 degrees! who knew it was that easy? thank you!
You're welcome!
It was so perfectly explained...absolutely got it💓
Thank you :-)
Very clear concept. You made my life easy.
Many many thanks for this session.
no worries
Thank you! Very clear and easy to understand
Glad it was helpful!
Amazing video! At around 6:00 however, the H+ does not attack, there is a proton transfer but the lone pair on the oxygen should attack the hydrogen in the end. Thank you so much! I have trouble with stereochem because it gets messy and I had trouble drawing structures in Haworth fashion but I have no trouble now!
thanks for your feedback :-)
lmao I said the same thing to myself. Awesome video though. Helped me understand. Do you have a video for Haworth to chair confirmations?
Thank you soooo much sir; this video is exactly what i was searching for.. it is so helpful : )
Thank you for your feedback. I am happy the video helped you :-)
Thank you so much! Hope you help more students in the future bc u amazin!!!
thanks Leah
Wow really good. You just won another subscriber. Thank you sir
How do you know if the #5OH group is going to be pointing up or down to form the alpha or beta anomer from the Fischer projection? I can make the Haworth, but it seems to me every fischer projection in this video has been with the #5OH pointing down, so I don't know how to make anything other than the alpha anomer.
Hi Andrew, recall that objective of the OH functional group located on carbon number 5 of the fischer projection it to react and form an intramolecular bond with the aldehyde functional group located on carbon number 1. It is therefore non-existant after the formation of the cyclic structure and therefore has no bearing on whether the newly formed haworth structure is alpha or beta. What you should be focusing on is the relative positions of the CH2OH located on carbon 5 (cyclic structure) and newly formed OH on the anomeric carbon formed on carbon 1 (cyclic structure). If they are opposite sides of the ring (i.e., one facing up while the other is facing down) then you would be looking at the alpha anomer. On the other hand they are on the same side of the ring (both facing up or both facing down) then this would be the beta anomer. Feel free to contact me if you are still struggling with this. Regards, MG :-)
"I'll be RIGHT DOWN"
"Left it UP to me"
Hey im from Poland. My english is so so. But this video is really good so I understand everything. Thank U ❤️
Dziękuję :-)
Was a little scared about quality when there was a music at the beginning, but it turned out to be very helpful tutorial! thanks!
You're welcome!
you are a life saver, thanks a lot
Thank you so much sir for posting this it is really a big help for me.
Thanks so much for this video!! It was so helpful for biochemistry!!!
No worries. Thanks for the comments :-)
Absolutely well explained.
Best explanation ever😊😊😊
Thank you! You make it easy to understand :)
You're welcome 😊
Thank a heap sir,,,,your presentation is so much excellent,,, i am from Bangladesh
Happy to help :-)
Thanks for this video..the concept is crystal clear....👍👍👍👍
I am happy you found it to be useful
This was very helpful and succinct. Thank you
This was SO helpful-- thank you so much!!
Thanks Ragan!
Awesome
Makes it so clear and easy💓💓
Thanks Hanaa :-)
Great.. thanks... I was confused in open chain chiaral No 5. here how OH becomes O and how vanished H. Now I'm clear. Because of rotation it happens nicely 🙂. Thank you, sir.
Are all saccharides has the same cyclic structure regarding on the position of oxygen between carbon 1 and 5? Could it be possible that the other functional groups will be attach to other carbon group (2, 3, 4)?
It depends on whether it would be thermodynamically stable or not. For example fructose forms a ring structure between C2 and C5 as opposed to C1 and C5. This gives a 5 membered ring structure as opposed to a 6 membered ring structure.
Chemistry is even more interesting with these animation ❤❤
Thank you very much, I had a hard time with those exercices, but now I'm alright !
Great to hear :-)
Great video, super clear. Thanks!
this video was so helpful! Thank you so so much!!!
You're so welcome!
Very helpful for med school students thanks a lot !
Nice video, thanks for the explanations👌
Glad you liked it!
Thanks. If it is L-gucose, do you still turn the Fischer projection 90 degrees down wards to for the Haworth projection?
THANK YOU SOO MUCH YOU LITTERALY SAVED ME
Amazing explanation.
Glad you liked it!
Thank you so much you save my life😊😊❤️
Happy to help
Mindblown. Thank you so much
Thanks Julia!
how the movement of OH group occurs in forming howarth projection from FISCHER projection at 5th carbon whats the solution for that, reply
Exactly my point
Thank you
Hi tysm this was super helpful. I'm still a little confused in assigning priorities in order to distinguish between the L and D galactose. I don't see how the carbon 6 has a lower priority than the carbon 4 molecule. Would you please be able to elaborate on that. I hope this doesn't sound confusing lol
This explains it so well thank you!!!!
Thank you, from a future doctor in Turkey!
This video is gold much thanks
Thanks Tyler :-)
Thanks a lot for this clear explanation!!
Lots of prayers for u sir🙌🏽💯👑
What a beautiful Video!
I think there is a bit of a misleading explanation at 6:09. The H+ ion doesn't attack the O- from the former carbonyl. It has no electrons with which to perform such an attack. The electrons from the O- are what act as the base in this step, which is essentially just an intramolecular proton transfer. I know a lot of biochem/ochem professors will count off if you draw curved arrows in the wrong direction, so thought I'd mention this.