Didn't listen to the whole thing because the parallel between MAC and Km is wrong; Km is a measure of affinity, not potency. A better parallel would have been MAC and Vmax. Additionally at one point in the beginning you said "inhibiting the chloride current" as a mechanism, which is also incorrect
Great video guys, very good explaination
excellent
Thank You!!!
how about lipid solubitiy for inhaled anesthesia?
Didn't listen to the whole thing because the parallel between MAC and Km is wrong; Km is a measure of affinity, not potency. A better parallel would have been MAC and Vmax. Additionally at one point in the beginning you said "inhibiting the chloride current" as a mechanism, which is also incorrect
I think the parallel to MAC is EC50 not Vmax
@@dr.emanibrahim9786 it is ED50. And the ED95 is derived in a similar fashion except its 95% of the subject(MAC95).