Thank you, that was an excellent explanation. You said exactly what my professor did but the way you wrote it out made it so much easier to understand!
Damn Semester tmrw and finding this today, and i'm like c'mon youtube put these on recommendations without anything useless This really helped me to understand the whole process thankee
Absolutely! And this actually explains the Bohr shift on how the haemoglobin's affinity for oxygen changes depending on the carbon dioxide concentration in different tissues/organs! :D see my other video on the Bohr shift!
Question - I know what you said is correct but I'd love if you could clarify why: why do the chlorine ions diffuse out of the erythrocytes, because I naturally would have thought the acidic hydrogen carbonic ions are 'used up' when they react and therefore the charge would be the same as before the hydrogen carbonate ions diffused back in? Thank you, I found this video very helpful :)
Yes, the concentrations of CO2, H+ and HCO3- within the red blood cells (RBC) will affect how much of this chloride shift occurs, but to put it in simpler terms... The point of chloride shift is to move the HCO3- ions out to the plasma, so to maintain the concentration gradient between RBC and the tissue fluid, to enable more CO2 to be converted into HCO3- form to be transported. The idea is to make it so as much CO2 can be transported away from the respiring tissues as possible. However to move the HCO3- ions out of the RBC and into the plasma, it requires a transport protein as charged ions normally cannot diffuse across the plasma membrane... And this transport protein is a cotransporter, meaning it'll only work if it also moves something in the opposite direction (kind of like the Na+/K+ pumps in active transport). And this "opposite" molecule is the chloride ions! In other words, in order for the transport protein to move HCO3- out, it also needs to move Cl- in, and vice versa. The exchange is on an one in, one out basis. Hope that makes sense? I hope that clears it up! And thanks for watching! :D
No I haven't. I am aiming to cover the whole spec but that does take time... Eventually I will have! For now, feel free to check out the other videos :)
THANK YOU THANK YOU THANK YOU! this video helped me out so much because online teaching isnt really anything these days.
So much better than other channels, you actually explain rather than just reading what happens. Thank you!!!
Thank you, that was an excellent explanation. You said exactly what my professor did but the way you wrote it out made it so much easier to understand!
Really Helpful, For those who come to see the comments before actually watching ... I would recommend watching this one ❤❤
Tomorrow, I have mock exams 😢 You are saving my day. Thank you so much!!!
As a 2nd year Biotech student, THIS WAS SOO HELPFUL for a recap😭❤️ thank you!
Carbaminohaemoglobin is the best word ever I’m gonna name my first born Carbaminohaemoglobin 🥰🥰🥰
😂😂😂
THANK YOU THIS VIDEO SAVED MY LIFE
you made it so simple and easy to understand !!! :)
you're an amzing teacher, i should be paaying for this kind of teaching. thank you so much
Really good video. Thanks!
Damn this video enlightened me so much I hope you make videos like this
best video on this chapter thank you
Thank you so much this was really helpful!!!!
Keep making these helpful videos take love from India
Thankyou this video was very helpful :)
omg thank you! paper 3 tmrw and this was so helpful :)
Thank you! Very helpful! (: Just wanted to say that at 3.33 it says CO! Surely we don't want carbon monoxide...
Opps! Typo error, thanks for pointing that out, well spotted! Thanks for watching :D
Damn Semester tmrw and finding this today, and i'm like
c'mon youtube put these on recommendations without anything useless
This really helped me to understand the whole process thankee
Hahahaha glad you found the video anyway!! Hope it'll help you next term after the summer break! :) Thanks for watching!
Just wanna say I love you
me too
You’re a lifesaver
Honestly ur a Legend i hope u kno that
Thank you very much.
Well done
Thank you so much for this video!!! One question though, what is the difference between plasma and tissue fluid?
Plasma is the liquid in blood. Tissue fluid is outside of blood vessels and surrounding the cells.
Thank you so much!! So does it mean after the whole process is reversed, the oxygen will bind with the haemoglobin that was dissociated from HHB?
Absolutely! And this actually explains the Bohr shift on how the haemoglobin's affinity for oxygen changes depending on the carbon dioxide concentration in different tissues/organs! :D see my other video on the Bohr shift!
@@BioRach just came from the vid. Got a level year 1 exams coming up. I love uou
Best explanation I've seen. Really easy to follow. Nice work!
Great explanation. Thanks
God bless you 😭😭❤️❤️❤️❤️❤️❤️❤️
Omg thank youuuu so much this video was so helpful👍
Wow👏👏
This was so helpful
thank you
THANK YOU SO SO MUCH
hi can you do a video on the liver please
Yes will do! It's high on my list cuz loads of people have been requesting it :) thanks for watching!
Summary at 4:32
Question - I know what you said is correct but I'd love if you could clarify why: why do the chlorine ions diffuse out of the erythrocytes, because I naturally would have thought the acidic hydrogen carbonic ions are 'used up' when they
react and therefore the charge would be the same as before the hydrogen carbonate ions diffused back in?
Thank you, I found this video very helpful :)
Yes, the concentrations of CO2, H+ and HCO3- within the red blood cells (RBC) will affect how much of this chloride shift occurs, but to put it in simpler terms...
The point of chloride shift is to move the HCO3- ions out to the plasma, so to maintain the concentration gradient between RBC and the tissue fluid, to enable more CO2 to be converted into HCO3- form to be transported. The idea is to make it so as much CO2 can be transported away from the respiring tissues as possible. However to move the HCO3- ions out of the RBC and into the plasma, it requires a transport protein as charged ions normally cannot diffuse across the plasma membrane... And this transport protein is a cotransporter, meaning it'll only work if it also moves something in the opposite direction (kind of like the Na+/K+ pumps in active transport). And this "opposite" molecule is the chloride ions!
In other words, in order for the transport protein to move HCO3- out, it also needs to move Cl- in, and vice versa. The exchange is on an one in, one out basis.
Hope that makes sense? I hope that clears it up! And thanks for watching! :D
@@BioRach Yes, I understand it as much as I probably need to at least! Thank you so much for such a thorough response :D
good job appreciated
Thanks for watching! :)
@@BioRach love your approach to the topic ❤❤
Haha thank you!! :D
great vid (:
Hi, Have your done chapter 14 hormonal communication ?
No I haven't. I am aiming to cover the whole spec but that does take time... Eventually I will have! For now, feel free to check out the other videos :)
💗💗💗
So much umm in the video but it was ok