The effect of dietary cholesterol on blood cholesterol & individual variability | Dr. Tom Dayspring

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  • เผยแพร่เมื่อ 3 มิ.ย. 2024
  • Does eating cholesterol raise our blood cholesterol levels? Why does this vary from person to person? How can you test where YOU fall on the spectrum? All your questions on dietary cholesterol answered.
    The usual extremes, “cholesterol is poison everyone should eat zero cholesterol" vs “cholesterol is always harmless”.
    We cover cholesterol absorption in the intestine, the effect on serum cholesterol, tests of absorption status, and actionable advice to lower risk.
    Subscribe for more free nutrition and health tips: bit.ly/2toMJ9u
    Connect with me:
    Facebook: / drgilcarvalho
    Twitter: / nutritionmades3
    Animations: Even Topland @toplandmedia
    References:
    link.springer.com/chapter/10....
    www.sciencedirect.com/science...
    www.ncbi.nlm.nih.gov/pmc/arti...
    www.nejm.org/doi/full/10.1056...
    boris.unibe.ch/64847/1/NEJMc1...
    academic.oup.com/eurheartj/ar...
    academic.oup.com/ajcn/article...
    onlinelibrary.wiley.com/doi/a...
    www.gastrojournal.org/article...
    Disclaimer: The contents of this video are for informational purposes only and are not intended to be medical advice, diagnosis, or treatment, nor to replace medical care. The information presented herein is accurate and conforms to the available scientific evidence to the best of the author's knowledge as of the time of posting. Always seek the advice of your physician or other qualified health provider with any questions regarding any medical condition. Never disregard professional medical advice or delay seeking it because of information contained in Nutrition Made Simple!.
    #NutritionMadeSimple #GilCarvalho
    0:00 Introduction
    2:09 How the body regulates cholesterol levels
    3:28 Intestinal absorption
    6:17 Esterified vs free cholesterol
    13:14 The Niemann-Pick, an intestinal cholesterol gateway
    16:46 Individual variability
    20:10 What happens to cholesterol after absorption
    30:18 The microbiome & cholesterol
    31:58 Phytosterols & other supplements
    35:48 Testing your cholesterol absorption
    40:27 Pharmacological Management
    43:45 Recap

ความคิดเห็น • 836

  • @0ptimal
    @0ptimal ปีที่แล้ว +9

    So we are kinda gambling by freely eating fat and cholesterol rich foods? If we don't know how our body is behaving with it? I knew there was variability in how food affects people, but it goes much deeper than I thought. Glad TH-cam recommended this to me.

  • @ThePapawhisky
    @ThePapawhisky 3 หลายเดือนก่อน +10

    I assume that most of us watching have some reason to be personally concerned. Here’s my question: if the tests and treatments are understood and ‘available’, why do most of us never get this high level of health support? Instead we’re learning on TH-cam what treatments we are not receiving.

    • @esthersmith3341
      @esthersmith3341 หลายเดือนก่อน +6

      Because your insurance company is determining what tests you need and what treatments you can get, not your doctor. I hate to get political here but how many congressional members have stock in insurance companies and pharmaceutical companies? How many lobbiests are paying them under the table? If we start cleaning house at the top, our health care will improve. The criminals at the top have the best health care.

    • @XAUCADTrader
      @XAUCADTrader 9 วันที่ผ่านมา

      This is exactly what I was thinking, but the answer is always $$$

  • @esotericsolitaire
    @esotericsolitaire 7 หลายเดือนก่อน +22

    Wow. Our bodies are so amazing. We should take a moment and meditate on this wondrous creation and thank it for all it does. I'm serious.

    • @StocksDoc
      @StocksDoc 3 หลายเดือนก่อน +6

      yes, thank God for creating such marvelous creatures

    • @johnumiastowski9501
      @johnumiastowski9501 19 วันที่ผ่านมา

      Yes, but meditating on this fact would be of no benefit to me. I'd rather spend the time reading scholarly reports.

    • @bobbyadkins6983
      @bobbyadkins6983 16 วันที่ผ่านมา

      Thank God for it. He created us.

  • @pegatrisedmice
    @pegatrisedmice หลายเดือนก่อน +3

    I don't think you can do much in terms of how digestible your content can be when you're presenting actual facts, because facts tend to be more complex than eat this, do that and you'll be fine. There's also the problem of other influencers crafting their "facts" such that they appeal to most people and confirm what individuals already believe, and that generates more clicks (it's not fat it's sugar type crowd for example). So I'm very happy you took your time to interview someone of such great knowledge and explaining abilities, because I was confused about this topic for a while but this video cleared it up for me in a matter of minutes (to be fair i did zone out ofter the explanation of low and high absorbers because that kinda answered my question but i will definetly revisit this). Thanks

  • @chainsong9546
    @chainsong9546 ปีที่แล้ว +7

    fantastic...I love how, unlike Peter Attia, he just lets the guest talk and doesnt constantly interrupt with anecdotes and digressions. Chapeau!

  • @texdentist
    @texdentist 10 หลายเดือนก่อน +11

    I went on a keto diet with 16:8 intermittent fasting 4-1/2 months ago. I have lost 41 pounds, and got my new lipid panel yesterday to compare to a November 2022 panel. After eating lots of eggs, bacon sausage, beef, butter, and mixing in chicken and fish for the 4-1/2 months, my total cholesterol dropped a little - 149 to 137. My HDL is too low and dropped from 36 to 34. But Triglycerides dropped from 138 to 69 and VLDL dropped from 25 to 14. LDL was unchanged at 88. The good news was that my Triglyceride to HDL ratio dropped from 3.8 to 2.0. A very good change in an important indicator. I was very worried that my high fat, and fairly high saturated fat diet would send my blood lipids skyrocketing. But they generally stayed the same or dropped considerably. I see doctors who predict both ways -- high fat will increase cholesterol or high fat/low carb will reduce cholesterol. In my case, it was the latter.

    • @eugeniebreida1583
      @eugeniebreida1583 5 หลายเดือนก่อน

      I am curious ofyour averagedailycarb intake during that 4.5 months-? Tia

    • @texdentist
      @texdentist 5 หลายเดือนก่อน +1

      @@eugeniebreida1583 I tried to keep it at 20 grams a day or less. I'm sure I went over on occasion, but not by much. I ate zero foods that were high carb during that time.

    • @eugeniebreida1583
      @eugeniebreida1583 5 หลายเดือนก่อน

      Thanks so much for your response. I once went on a strict STRICT paleo carnivore (no carbs) for one month, and reduced ALL of my inflammation - to zero. I also reduced my carbs to zero.
      In the end this restriction caused me great problems in terms of hormones (cortisol raised) - too much energy/inability to find restful sleep. So I ditched it.
      I think I am going to try a strongly meat w/greens & very low carb vegges so that I do not go off the charts ketogenic (can still sleep) but finally knock off the know crap foods (grains, nightshades, bad seed oils a(which I dont consume anyway) but maybe the nuts which I do, in moderation. Not sure about my flax seeds/flax oil (omega3's, but not only).
      Any idease welcome. However I'm not a fan of pork for inflammation, nor highly processed meats (bacon in USA, etc). Thanks for your info!@@texdentist

    • @DonaldBraman
      @DonaldBraman 2 หลายเดือนก่อน +1

      Just be aware that most low carb diets show results in year one that are reversed in year two. That won't be true for everyone because of individual variability, but it is true on average. I hope it works for you!

  • @hendrikdebruin4012
    @hendrikdebruin4012 ปีที่แล้ว +119

    If I had a biology teacher like this at school chances are I would have become a doctor. Fascinating insights from an extremely intelligent and knowledgeable person who has the ability to explain difficult concepts and science in simple terms. I salute you sir - you are a rare commodity indeed. All I can say is thank the lucky stars we did not have to design the chemical , biological and electrical functioning of the body or we would never have existed. How in the name of everything did this all come to be?

    • @pragooutube
      @pragooutube ปีที่แล้ว +7

      So much evidence of brilliant design! It's obvious there must be a Designer.

    • @cameronbethea123
      @cameronbethea123 11 หลายเดือนก่อน +6

      @@pragooutube Maybe, but if so, who designed the designer ? A designer that can design life so complex must itself be vastly more complex than the life it designs, but if the designer itself wasn't intelligently designed, then something even more complex than us, came from nothing ?
      I believe its possible that there is a creator, and I like to imagine that there is one, but It's not possible to say with any degree of certainty that one is necessary to explain the universe.
      That belief requires you to assume that there must be a first cause of all things, and that this cause is a specific intelligent being that somehow exists outside the universe entirely, which, although possible, it can't be proven, and isn’t the only conceivable possibility.
      Maybe the universe is all that there is, and it is cyclical in nature, running in a loop for infinity, like a broken record, meaning it causes itself, or maybe there is an endless multiverse.
      It isn’t possible to prove or disprove any of these theories right now, so you can’t accurately say if they are more or less likely than a creator being the first cause.

    • @pragooutube
      @pragooutube 11 หลายเดือนก่อน +1

      @@cameronbethea123 I've come to the realization that the amazing complexity of life, the precision, means that I have to humbly accept that the Designer's origins must be beyond my scope of comprehension- beyond my realm of understanding- miraculous if you will.

    • @niranjanpaul2176
      @niranjanpaul2176 10 หลายเดือนก่อน

      @@pragooutube sure it's too perfect to be an accident

    • @niranjanpaul2176
      @niranjanpaul2176 10 หลายเดือนก่อน

      @@pragooutube like how many actually expected the covid was going to happen to humanity

  • @davidsuzukiispolpot
    @davidsuzukiispolpot 11 หลายเดือนก่อน +76

    Regarding individual variability: I was exercising a lot and eating the recommended low fat diet and my body did not have excess fat, but I felt like I was not robust or strong and my cholesterol was going up. My doctor recommended statins. I asked what lifestyle I could do but when he said " eat less fat" I replied that was not possible since I already ate very little fat. He then said I was likely genetically predisposed to why cholesterol.
    Later, when I switched to a fairly high fat high cholesterol, low carb diet and I told him look. My cholesterol levels are very good and I eat a lot of cholesterol. He said maybe I have genetically predisposition to low cholesterol.
    I guess that doctor thinks I had successful gene therapy. In my case, I think my low fat diet contributed to a poor lipid profile and the general health recommendations and assumptions of doctors are not correct.

    • @janiesherwood6403
      @janiesherwood6403 10 หลายเดือนก่อน

      That is Soo funny, that dr doesn’t know his patient 😉

    • @signs80
      @signs80 9 หลายเดือนก่อน +12

      It's likely because you were eating pretty poorly on the low fat diet. It isn't mentioned in this video, but studies show that eating refined sugar and refined carbs on a calorie per calorie basis is effectively nearly as bad as eating those calories as saturated fats.

    • @k.h.6991
      @k.h.6991 8 หลายเดือนก่อน +7

      For heart health it's the quality of the fats that matters. In other words: eat nuts and seeds.

    • @alipainting
      @alipainting 7 หลายเดือนก่อน +9

      This is EXACTLY my story, - what the doctor said word for word and what I did: zero fat, 100% carbs, which caused hypercholesterolemia. He said it must be familial. At that point I turn to Google and TH-cam 🎉😅

    • @ianlanford6922
      @ianlanford6922 7 หลายเดือนก่อน

      @@signs80 he said he is exercising a lot. 99% who exercising knows, that eating junkfood refined sugar and mcdonald is big NO NO. occasionally yes but not everyday or every so often.
      imo. the problem is that if you eat less fat. your body tried to make more. like video said. dietary cholesterol absorption for most ppl is half. but because he lack of it. the body then create more by creating from body fat and recycle it via bile/instentine.
      eating more fat then reverse this effect and body doest need any more cholestorol. hence cholesterol going back to normal

  • @dpwright32
    @dpwright32 ปีที่แล้ว +259

    Gil, you are doing such an awesome job! You rescued me from the depths of the low carb, “only the small dense ldl are bad”, “grass fed butter is good for you”, etc.. camp. I have devoured your lessons on how to do my own research. While I had no symptoms of heart disease, part of my 2 year journey to good health (260lbs to 160lbs) included getting my own additional lab work done, including a calcium ct scan, which showed a very high score. I’ve researched as many things as possible, and you single handedly got me to understand “don’t trust someone based on their credentials, look at the data…”. Anyway, thank you SO MUCH! I am spreading the word to my friends. And this interview with Dr Tom Dayspring is a MASTERCLASS!

    • @ricardo1522
      @ricardo1522 ปีที่แล้ว +12

      "including a calcium ct scan, which showed a very high score"
      What was your score before you started low carb compared to when you stopped?

    • @dpwright32
      @dpwright32 ปีที่แล้ว +23

      @@Krunch2020 no, it was not low carb, I apologize for the confusion. It was essentially just slightly higher protein and a ~500 cal per day deficit or more and exercise. I was trying to say that I got caught up in the low carb content online and got convinced about seed oils, grass fed butter, and statins are all bad. But kept searching since most of that line of discussion is weaker evidence in my clearly laypersons view so far. I’ve learned to look at broader swaths of evidence. I’m fully open to the possibility that I’m still on the wrong track, but am trying to constantly prove my views wrong, versus only reinforcing the ones I have had, or currently have.

    • @dpwright32
      @dpwright32 ปีที่แล้ว +17

      @@Krunch2020 and I don’t just listen to Gil, I devour many channels, have read multiple books such as all of the plant paradox, the low carb guidebooks, Metobolical, etc…. I just particularly appreciate Gil’s style and way of presenting the research.

    • @corvoattano9303
      @corvoattano9303 ปีที่แล้ว +11

      @@dpwright32 Normally I would be jumping for joy when I find a rational person like you in the comments. However I've come to expect such quality from Gil's audience.

    • @larryc1616
      @larryc1616 ปีที่แล้ว +1

      Stay away from quacks like Ken berry 🤡💩

  • @DL-rl9bd
    @DL-rl9bd 2 หลายเดือนก่อน +3

    I had a lipid panel done the day after attending a kids birthday party, where I spent the day eating pizza, snacks, soda, cake, and ice cream. My lipid panel turned out pretty bad, and my triglycerides were in the 300s. That particular day was an exception, as I do not regularly eat like that.

  • @Dan-dg9pi
    @Dan-dg9pi ปีที่แล้ว +8

    Gil, the point about the bell curve within the population is extraordinarily important. We too often assume that the entire population is the same. Instead, what if every time we do a study there are 2 or three or five different subpopulations that react differently to an input. Suddenly, all those meta-analyses might be a lot less comparable if certain subpopulations are not represented or the input is slightly different. As you know, this is called Simpson's paradox and we ignore it at our peril.

  • @gregmeissner9960
    @gregmeissner9960 ปีที่แล้ว +34

    This guy’s hilarious! I love how he personifies cholesterol molecules. Brilliant teacher.

    • @michealfriedman7084
      @michealfriedman7084 ปีที่แล้ว +2

      No disrespect..
      He reminds of Grandpa Munster of The Munsters. Lol

  • @sd200man
    @sd200man ปีที่แล้ว +13

    The complexity of our systems is beyond amazing. This has given me a new appreciation for how complex the cholesterol issue is.

    • @kamerad4212
      @kamerad4212 ปีที่แล้ว +1

      Agreed! Everything about humans is being revealed as beautifully efficient and yet so complex.

  • @billc7211
    @billc7211 หลายเดือนก่อน +1

    Another great teacher in the medical community! Thank you for allowing Dr Dayspring your platform to explain this.

  • @Radjehuty
    @Radjehuty ปีที่แล้ว +47

    I sincerely hope anyone that watches this knows how much of a privilege it is to have this video as a resource. It's such an excellent overview and easy to understand for a concept that has a lot of nuance. It flies in the face of any diet that professes black & white verbage to describe whether dietary cholesterol is good or not. Maybe I'm in the minority, but I love hearing the "it depends" kind of answer. I much prefer precision over easy when it comes to answers about health.

    • @ashleyfarias449
      @ashleyfarias449 ปีที่แล้ว +1

      ditto!

    • @kenmken
      @kenmken ปีที่แล้ว +5

      This video was incredibly informative, but I really don't know if "it depends" is the most honest conclusion, and I'm a bit dissapointed he did not discuss further specifics. It seems to me that hypercholestorolemia is a relatively common condition, and I can't find any information on the incidence rate of hypocholestorolemia, which is also linked to adverse health effects. If like I suspect the latter is much less common, perhaps it is misleading to say "it depends" like its some 50/50 split. With the way he talked about it, he portrayed hypo-aboserbers of cholesterol as having a blessing, so certainly not an adverse condition, unless ofcourse the body is also incapable of producing enough on its own. Seems like it varies how harmful dietary cholesterol can be to people, not that "it depends whether its good or bad". With that in mind and the fact that food is a package deal and the healthiest foods and diets are consistently rich in plants, it is a weird conclusion to make

  • @Nicksonian
    @Nicksonian ปีที่แล้ว +35

    After this lesson, I don’t understand how higher HDL has gotten the reputation as being good, if high HDL is a sign of hyper-absorption.

    • @lenguyenngoc479
      @lenguyenngoc479 ปีที่แล้ว +16

      What you asked scientists already thought of it. They pick individuals with genetically high HDL. They found no protection from cardiovascular diseases whatsoever

    • @AppleMasterChris
      @AppleMasterChris ปีที่แล้ว +3

      This is why physicians have moved away from HDL as a good indicator. We now use HDL/LDL ratio :)

    • @stx7389
      @stx7389 ปีที่แล้ว +3

      @@AppleMasterChris even that is not good, LDL or APO-B is key

    • @lenguyenngoc479
      @lenguyenngoc479 ปีที่แล้ว +1

      @@AppleMasterChris No....like the guy above said, ApoB only.

    • @Nicksonian
      @Nicksonian ปีที่แล้ว +1

      @@StanDupp6371 Just because old people have high HDL levels doesn’t mean that the HDL level has anything to do with why they’ve lived so long. Prove the cause and effect. You can’t. Attempts to improve cardiovascular health by raising HDL has largely failed.

  • @richclark6265
    @richclark6265 2 หลายเดือนก่อน +1

    A pleasure listening to an "enthusiastic master" of his subject. One able to explain complex subjects to the common man such as myself. Thanks for the great video!

  • @MKstudiovideo
    @MKstudiovideo ปีที่แล้ว +57

    At first, I played the video with the notion that I already knew everything important about dietary cholesterol and its effect on our cholesterol (since I watched Gil's previous video on this topic). Yet, I learnt a ton of new information. I really hope more people like Tom Dayspring exist who are experts in their domain of interest and who can simply explain such a difficult topic to a lay person. And I really hope you Gil will be able to find another such excellent people who are willing to do those epic interviews with you because it's a huge service for the world. Thank you both!

    • @Harleyyelrah
      @Harleyyelrah ปีที่แล้ว +1

      Pô I 😊

    • @billytheweasel
      @billytheweasel 3 หลายเดือนก่อน

      He's great. I've been a Dr Dayspring fan for over a decade. Glad he's with Dr Peter Attia now.

  • @maimai-bd2iw
    @maimai-bd2iw ปีที่แล้ว +20

    I am only a high school student, but I find your work very inspiring. ❤

  • @adomasjasiukenas1425
    @adomasjasiukenas1425 ปีที่แล้ว +63

    This was one of the best lectures I have ever listen about nutrition. This is what we really can call “nutriton made simple”. Great analogies. His passion reminded me of R. Taylor. I love people who are passionate about their thing and spread good, science based information in a understandable manner 🤩

    • @Better_Call_Raul
      @Better_Call_Raul ปีที่แล้ว

      29:30 A man with an HDL of 60 is in the normal range. Why is that a possible sign of a hyper-absrber? Is it a sign only if the man's LDL is high? 🤔

  • @hugomarquez3189
    @hugomarquez3189 ปีที่แล้ว +15

    I understood, very well explained, it still makes sense to not consume cholesterol to err on the safe side. Why add more to what the body already produces? Maybe 25 to 50% of people won’t have an issue with it, but why risk it? Because it’s not just the cholesterol, that’s just one, then you have to add the saturated fat.

    • @Davygan
      @Davygan ปีที่แล้ว +2

      Therefore the guidelines say: ‚As little dietary cholesterol as possible.’

  • @elduderino1329
    @elduderino1329 ปีที่แล้ว +28

    I've never heard a such a detailed, comprehensive explanation about this subject. It's so information dense that had to rewatch many parts of it to understand it. I feel privileged to be a subscriber to your channel.

  • @newyorkguy158
    @newyorkguy158 8 หลายเดือนก่อน +4

    There was a lot of new and valuable information for me here. What was missing was a discussion of the relationship between dietary fatty acids and cholesterol synthesis. That would provide a more complete picture. I wonder why he didn't discuss the role of fatty acids?

  • @jimmccall8030
    @jimmccall8030 ปีที่แล้ว +20

    This is SO HELPFUL. I am a hyper absorber with very high ApoB, high LDL, high HDL and have been eating 3 eggs daily. Going to switch to one whole egg and egg whites. Thank you. I’m reading and watching all of Dr Dayspring that I can find. Also I really appreciated your recent debunking of the saturated fats are fine report

    • @mark-ge8dr
      @mark-ge8dr 4 หลายเดือนก่อน +5

      Why continue eating one egg a day if you’re a hyper absorber?

    • @billytheweasel
      @billytheweasel 3 หลายเดือนก่อน +1

      @@mark-ge8dr My question too. I started Ezetemibe and stopped eating eggs, etc.

  • @maticpolicnik1585
    @maticpolicnik1585 ปีที่แล้ว +4

    Awesome video! Great information, good animations and easly digestable content.

  • @julianbrown2228
    @julianbrown2228 ปีที่แล้ว +5

    What a lecture on Cholesterol, absortion and pathways... As always, great video.

  • @nikkiguerlain
    @nikkiguerlain ปีที่แล้ว +3

    Oh my gosh! Your guest is the best ever! He’s so animated and genuinely excited and knowledgeable.

  • @DrBradStanfield
    @DrBradStanfield ปีที่แล้ว +176

    This is an amazing discussion. Love that this high quality and evidenced based information is now available to the public

    • @larryc1616
      @larryc1616 ปีที่แล้ว +1

      Yes, the facts are here but your common layperson is easily manipulated and fooled by quacks like Ken berry. You and gil are straight shooters. A debate with Ken berry about the carnivore diet can help laypeople understand the truth about nutrition and health. How do you combat quacks from killing laypeople?

    • @MrRobertFarr
      @MrRobertFarr ปีที่แล้ว +3

      Yes. There's some interesting. Papers, available to read about eggs online. Did you see any good ones in free to access journals?

    • @MrRobertFarr
      @MrRobertFarr ปีที่แล้ว +5

      Hi, I am Robert Farr BSc Hons. A volunteer Scientist in England.

    • @MrRobertFarr
      @MrRobertFarr ปีที่แล้ว +5

      Mechanisms can be a bit misleading. It, allows folks to have a cheap, educated guess at what might be going on.
      I devised, a reaction mechanism once, by coupling together two accepted mechanisms.
      I asked, to see, my fellow students ideas, but, they would not show me, their ideas.

    • @tombullish3198
      @tombullish3198 8 หลายเดือนก่อน

      Monologue/seminar*

  • @jacksarem9480
    @jacksarem9480 2 หลายเดือนก่อน +3

    Thank you for the information. This was the best explanation of the cholesterol management

  • @lioneltrains7865
    @lioneltrains7865 ปีที่แล้ว +2

    Thank you both for this video..I could listen to him all day…easy to understand yet gives you the somewhat technical terms as well

  • @amyfriedlander7850
    @amyfriedlander7850 ปีที่แล้ว +3

    Fantastic video. Now I need to watch it at least a couple more times to really understand and absorbe the lessons. Thank you very much.

  • @PileofKyle
    @PileofKyle ปีที่แล้ว +2

    Thank you for getting this guest on to share this important information in such a clear simple explanation.

  • @Firebuck
    @Firebuck ปีที่แล้ว +10

    Excellent video. Dr Dayspring does a great job of presenting this information. So many nuances!

  • @kathleenkulp240
    @kathleenkulp240 ปีที่แล้ว +8

    Had to listen twice, but what a wealth of information!! Gil, you are a blessing! Thank you for all your time and efforts.

  • @Nicksonian
    @Nicksonian ปีที่แล้ว +7

    If you tend to the hyper-absorption side, an additional 15 to 25 percent absorption from dietary cholesterol seems significant. If, say, a quarter of the population is on the hyper-absorption side, then how has “dietary cholesterol doesn’t matter” become a thing? Of course, I’m playing dumb there. There are too many people out there pushing animal products.

  • @rubygaster6266
    @rubygaster6266 ปีที่แล้ว

    Thanks for giving him the space to talk and give US all the good info

  • @Chameleon569
    @Chameleon569 ปีที่แล้ว +6

    Great content, thank you for all you are doing. I like your gentle and non-argumentative style of delivery. 🙏

  • @danjones3085
    @danjones3085 ปีที่แล้ว +2

    What a great guy, pleasure to listen and learn!

  • @danyyboye
    @danyyboye 11 หลายเดือนก่อน +6

    Fantastic lecture! My mother has familial hyperlipidemia with total Cholestrol in the 300s to 400s, HDL in the 120 region. I (male) don't have such high levels myself but my total runs around 250 with HDL around 70, LDL around 150. So I guess I got partial genes from my mother, not full loss of function.
    I went on full vegan (no dairy or animal products) diet for 2 months and my Cholestrol only went down by 15points. It was very frustrating but now I see why. Thank you for this illuminating lecture. I think I'd be one of those who could benefit more from absorption blockers like Ezetimibe. Also perhaps invest my time more on diet changes that target better Cholestrol elimination (soluble fibers Flax seed etc..)
    Again thanks a whole bunch to both of you. I hope many providers will see this video and learn. No one suggested any genetic test for my mother. They just put her on statin and that's it. Seems like she could benefit more if Ezetimibe is added.
    (BTW gonna have to return the phytosterol supplement that's on the way. Y'all might just save me from some damage on that front. Thank you!)

  • @Schatzie301
    @Schatzie301 ปีที่แล้ว +29

    What a brilliant explanation. I’ve been studying nutrition for over 50 years and this is the best and most comprehensive discussion I’ve ever seen.

    • @erharddinges8855
      @erharddinges8855 ปีที่แล้ว

      You are a dog?

    • @AndyMorrisArt
      @AndyMorrisArt 4 หลายเดือนก่อน

      far too comprehensive for me. I'm just as uncertain now as before I watched it.

  • @user-ew2ju3gr6v
    @user-ew2ju3gr6v ปีที่แล้ว +8

    I worked with Dr Dayspring in the past at a laboratory. Brillant physician. Good to see him again.

  • @apriljohnson6191
    @apriljohnson6191 ปีที่แล้ว +20

    Thank you for this!! LOVE LOVE LOVE. This video puts a lot of pieces together from your previous videos on ApoA and ApoB. I think I can go back to your other videos on the subject and get a lot more out of them now.
    I had questions on triglycerides and fatty liver. Can you do a video on this? It’s an epidemic in the United States and for those who have it, not a lot of guidance. I would love to see Dr. Tom Dayspring, MD, speak on the subject if he was inclined. :)
    Thank you both for this extremely informative video.

  • @TylerArbour
    @TylerArbour ปีที่แล้ว +3

    Love this guy! Thanks Dr. Dayspring for your enthusiasm and sharing your knowledge. 😅

  • @jimcarbone2748
    @jimcarbone2748 ปีที่แล้ว +68

    Outstanding! If we only had more people like him to explain biology in such simple terms, we would all be better educated and equipped to manage our health in a targeted, meaningful and effective way. Kudos to you Gil for bringing his knowledge to the public.

  • @omittapir5986
    @omittapir5986 8 หลายเดือนก่อน +2

    I was totally engrossed listening to him! He have such an interesting ability to make the cholesterol, LDL and rest of the players in the story of high cholesterol come to life. I just imagined them as tiny walking talking cartoon characters and totally was into it. Wow! What a great interview. Thanks for inviting him to give such an amazing, eye opening interview.

  • @martinbrown9980
    @martinbrown9980 ปีที่แล้ว +55

    That was a very interesting discussion. Could you follow that up with a discussion on saturated fats effects on blood cholesterol.

    • @danm8004
      @danm8004 10 หลายเดือนก่อน

      He said early on in this video that there was none.

    • @eugeniebreida1583
      @eugeniebreida1583 5 หลายเดือนก่อน

      Yes! Please a similarly informative vid re Sat Fat Consumption and chol/lipid levels that result.

  • @mathewmathew08
    @mathewmathew08 9 หลายเดือนก่อน

    Thanks a lot. The extra illustration included in the interview are very helpful to me.

  • @isabellezablocki7447
    @isabellezablocki7447 ปีที่แล้ว

    Wow, that was amazing information and that explains a lot even though I did not fully understand the details. Thank you Gil.

  • @fignewton8690
    @fignewton8690 ปีที่แล้ว +26

    Was on a fairly strict vegan diet, HDL 34, LDL 64, cholesterol 121, triglycerides 116. Went to the hospital with chest pains with 50% blockage in mid and 90% blockage in distal right coronary artery! Clearly my lipid profile is not indicative of this kind of blockage. I take a low dose statin now….I am more inclined to believe the newer theories of HDL to triglyceride ratios being more predictive of CAD since mine are high. The Norman pick cells are absolutely essential in cholesterol transport both in the gut and in the lysosomes of the cells. People low in this protein are linked to Alzheimer’s and dementia….
    So I think there needs to be more independent research on endothelial damage causing plaque build up rather than a just a high lipid profile. I am also suspicious of high glucose/insulin levels (metabolic syndrome) causing this damage since so many diabetics lose eyesight, limbs, kidney function and healing issues.
    Our bodies are really smart, I can’t see them making a critical heart mistake over something (cholesterol) that is produced in the body and so critical for physiologic function including nerve and cell membranes.

    • @jzen1455
      @jzen1455 ปีที่แล้ว +2

      There is a study that showed a U-shaped correlation between LDL levels and mortality. Participants of the study with the lowest levels of LDL and highest rate had higher rates of death. I think they factored out between those who took cholesterol lowering meds.

    • @fignewton8690
      @fignewton8690 ปีที่แล้ว

      @@jzen1455 I am familiar with the study. Check out A reassessment and proposal for food based recommendations.

    • @fignewton8690
      @fignewton8690 ปีที่แล้ว +1

      @@jzen1455 it has to do with saturated fats and health

    • @dvdmon
      @dvdmon ปีที่แล้ว +6

      @@jzen1455 Gil talks about this effect and how it can indicate "reverse causality" based on the preponderance of evidence and lack of additional data around how LONG these people had had low cholesterol. IE, you can have very high cholesterol for decades, adding to a plaque burden, but then start eating better, but still die because of all that plaque that's built up and eventually causes a fatal heart attack.

    • @dvdmon
      @dvdmon ปีที่แล้ว +3

      My main question would be how long did you have these low numbers compared with how long you had higher numbers (from a presumably different diet)? IE, you can't blame the last diet you were on, unless it's something you've been on for many years, with causing cardiac issues, which normally take DECADES to develop. The only way to determine this is to get an angiogram right before switching diets, so you know the "baseline" plaque burden. Now, I'm not suggesting that vegan diets by themselves can or should decrease plaque the way some vegan doctors suggest (like Esselstyn or Ornish), but there's some evidence that they can halt progression if done in a certain way - IE a vegan diet that also avoids refinec/processed foods, and saturated fats (from tropical oils primarily). That doesn't mean you are out of the woods if you adopt one of these after eating "normal" diet for decades and have built up loads of plaque. It may halt progression, but you also may be close enough to an event that even a two week vacation where you end up eating lots of vegan junk food could tip you over. Not suggesting that's what happened to you, I just think that it's impossible to implicate a diet as a cause (or a cure) if it is not done a) consistantly, and b) for a relatively extended period of time - say 3 or 4 or more years?

  • @faisal-ca
    @faisal-ca ปีที่แล้ว

    Great content. I will be getting tested more often.

  • @IIGBII
    @IIGBII ปีที่แล้ว +1

    This is a very informative video, thank you for making it.

  • @JerryTeixeira
    @JerryTeixeira 9 หลายเดือนก่อน +1

    Thanks for this, Gil. Good interview with Tom

  • @rdmckeever7645
    @rdmckeever7645 ปีที่แล้ว +10

    Totally eggselent. Doctor Dayspring explained the complex pathways & the many variables in a way that made it easily understood. Looking forward to many more videos like this. Thank you for this channel...

  • @vicentecueto8152
    @vicentecueto8152 ปีที่แล้ว +1

    Very interesting lecture. Thank you so much!

  • @levinelson3508
    @levinelson3508 ปีที่แล้ว +2

    Great video. Thankyou for doing the recap. Very helpful

  • @kevinharris8242
    @kevinharris8242 ปีที่แล้ว

    Looking forward to digging into this one Gil. When a world expert speaks, its good to listen 😀

  • @karmella5606
    @karmella5606 ปีที่แล้ว +2

    Just wow !!!! What a science and what a great dr. Tom !

  • @jhtvideo
    @jhtvideo ปีที่แล้ว +1

    Great video -- like the long format, wanted it to keep going at the end.

  • @peterfaber7124
    @peterfaber7124 ปีที่แล้ว +1

    Nice one! Learned a lot of new things from this video.

  • @utpalchattopadhyay
    @utpalchattopadhyay 7 หลายเดือนก่อน +1

    Just outstanding! Please continue doing this nobel work!

  • @andrewstuhr8626
    @andrewstuhr8626 ปีที่แล้ว +2

    This guy is a joy to listen to!!!

  • @tofu-munchingCoalition.ofChaos
    @tofu-munchingCoalition.ofChaos ปีที่แล้ว

    So interesting! Thanks for this. I thought it would be the usual response but it was much more.

  • @yogiyoda
    @yogiyoda ปีที่แล้ว

    Thank you for the great interview!

  • @rumidude
    @rumidude ปีที่แล้ว +1

    OMG, I finally found an understandable explanation of dietary cholesterol effects on serum cholesterol.

  • @stephenyoud6125
    @stephenyoud6125 ปีที่แล้ว +2

    Thank you so much for that. It was totally awesome. So complete a description and presented in an easy to undersatnd way by a clear expert in the field. very passionate and with a excellent and entertaining manner Dr Dayspring was amazing

  • @patrickvanmeter2922
    @patrickvanmeter2922 ปีที่แล้ว +13

    Thank you so much for this. I'm 81 and you have answered questions I have had since I became old enough to say the word Cholesterol. Getting a little schooling on this has helped me understand where to go from here. Thank you again. Subscribed and liked.

  • @janapeony8561
    @janapeony8561 ปีที่แล้ว +1

    the best EVER explanation about cholesterol ,Thank you so much!

  • @felicisimomalinao1981
    @felicisimomalinao1981 ปีที่แล้ว +1

    Much thanks Dr. Carbalho for featuring Dr. Dayspring.

  • @travisporco
    @travisporco ปีที่แล้ว +1

    It is so good hearing people who really know what they're talking about!

  • @mrddcass6540
    @mrddcass6540 ปีที่แล้ว +1

    This was an excellent clarification.

  • @shiv7743
    @shiv7743 ปีที่แล้ว +1

    Dr. Tom is an incredible speaker.

  • @susaaklilu7536
    @susaaklilu7536 11 หลายเดือนก่อน

    The best lecture i have ever had
    Thank you so much much

  • @quinterodpablo
    @quinterodpablo ปีที่แล้ว +12

    Thank you very much for this video, Dr. Gill and Dr. Tom. It's a pedagogical content I'll go back to for reviewing and keep learning. The duration of the video was fine. It's a complex topic that needs several complementary videos. As some users have already suggested, I think it would be a great idea to have a similar interview material that goes through the metabolism, testing and individual genetic variability related to other lipids (triglycerides, saturated fat, omegas, phytosterols, etc.). I'm particularly interested in triglycerides and saturated fat. Once again, thank you very much for your professional and pedagogical work. Good vibes to all the team. 👍

  • @VinodSV
    @VinodSV ปีที่แล้ว +20

    Never understood how my body is ending up with large quantities of lipids. Its a true masterclass, capable of saving millions of lives. This video should be a lecture in all medical schools.

    • @billytheweasel
      @billytheweasel 3 หลายเดือนก่อน

      All docs HAVE to know this if CVD is the #1 killer.
      smdh

  • @Mcvthree3
    @Mcvthree3 ปีที่แล้ว

    This was fascinating. Thanks, Gil!

  • @pamelaandpabloortiz6250
    @pamelaandpabloortiz6250 ปีที่แล้ว +19

    I was a registered nurse for over forty years and while the experts presented are clearly knowledgeable in their fields I’m finding these videos to be hard to understand on first viewing . I have always found the way you deliver information to be very easy to comprehend . This is not to show any disrespect to your guests but emphasize the importance of your summaries at the end . I went totally plant based four months ago and total cholesterol only dropped 18 points which was very disappointing . Please continue with your very easy to comprehend presentations. Thank you .

    • @Nicksonian
      @Nicksonian ปีที่แล้ว +1

      I don’t think it was difficult to understand. I went back and listened to a few lines again for clarification. I have listened to a fair number of videos about cholesterol, but I have no medical training.

    • @NutritionMadeSimple
      @NutritionMadeSimple  ปีที่แล้ว +15

      the interview format is relatively new for me so I´m trying to get the hang of it and trying to figure out the best way to present them as we move forward (short snippets? long form 1-2h convos? break them down into 2 or 3 parts?) , so your feedback is important!

    • @Nicksonian
      @Nicksonian ปีที่แล้ว +21

      @@NutritionMadeSimple Perhaps some viewers are intimidated by longer videos, or just think, “I don’t have time for this.” But this particular video is best watched all at once to absorb the overall concept and how it all links together. Some of us are hyper-absorbers of information while others are hypo-absorbers. Ha, ha, get it?

    • @lanazak773
      @lanazak773 ปีที่แล้ว +6

      @Pamela and Pablo Ortiz Thank you for your comment, I feel the same way. I want the information to be "Made Simple" and I also like to see some practical suggestions. I'm really loving this channel (I'm burnt out on Keto and IF), and so far the "what I eat in a day" video has been the most helpful (and most simple).

    • @Pixel-junkies
      @Pixel-junkies ปีที่แล้ว +2

      @@NutritionMadeSimple probably snippets with you declouding said snippets. I found it fine, but I have been reading about these things for like ever so it just filled in a few blanks for me.

  • @TheRst2001
    @TheRst2001 ปีที่แล้ว +6

    Interesting to learn how the different ways cholestrol is absorbed or extracted and different medical methods of inhibiting or removing, thanks 👍

  • @cynthiaktaylor5585
    @cynthiaktaylor5585 ปีที่แล้ว +1

    EXCELLENT INFO! Thank you…

  • @theflyingdutchman787
    @theflyingdutchman787 ปีที่แล้ว +4

    Wow, even I can understand this form of medical explanation. What a great teacher.

  • @mdgraystone
    @mdgraystone ปีที่แล้ว +2

    Wow, that's a lot of good information. My brain almost exploded! I guess I'll re-watch...

  • @zedgarden
    @zedgarden 3 หลายเดือนก่อน +2

    Simply amazing. Watched twice. Thank you

  • @nomi6798
    @nomi6798 ปีที่แล้ว

    I feel I need to listen to this video two o three more times with pen and paper. Super interesting. Thanks!

  • @marknasia5293
    @marknasia5293 9 หลายเดือนก่อน +3

    Wow, what an excellent deep dive from the subject matter expert. Honestly, broken down in a way to understand the function and pathways. testing and options could really increase a patient’s ability to manage high cholesterol levels. I am grateful you had Dr. Tom D. on to explain this. ❤

  • @bartcop2742
    @bartcop2742 6 หลายเดือนก่อน +3

    You were right in the intro to this video - This really is one of the best all around explanations I have ever heard. Thanks for posting this.

  • @chrisrobbo
    @chrisrobbo ปีที่แล้ว +1

    Very informative, thank you.

  • @DrDGr2
    @DrDGr2 ปีที่แล้ว

    So much knowledge! Thank you

  • @wadehampton1737
    @wadehampton1737 4 หลายเดือนก่อน +1

    Thank you for the recap. Golden...

  • @user-bo6nm9tr1q
    @user-bo6nm9tr1q 2 หลายเดือนก่อน +2

    Muchísimas gracias por este video y esta entrevista. Me encantó la forma de explicar del Dr. y ahora también soy su fan.

  • @wck2150
    @wck2150 ปีที่แล้ว

    Wow, just thanks. This was awesome.

  • @michellecoffee7062
    @michellecoffee7062 ปีที่แล้ว +20

    Love your content! This is one of several key videos that convinced me to change my diet and do something about my cholesterol levels. All of my family has high cholesterol. In December, my total cholesterol was 391, LDL was 282. My family has been convinced that cholesterol doesn't matter. I finally decided to do something and went on a plant based diet in mid January. Before I ate mostly vegetarian but loved cream and butter (LOTS of them). After going vegan, my total cholesterol is down to 207 and LDL is down to 118. I expected a little bit of a drop, but nothing this dramatic! Thank you for taking the time to make these informative videos!

    • @NutritionMadeSimple
      @NutritionMadeSimple  ปีที่แล้ว +4

      that's incredible, great job!!!!!!

    • @Crowmother13
      @Crowmother13 11 หลายเดือนก่อน

      My cholesterol is high ish. And I have cardiovascular disease. Stage 1 and Stage 2 hypertension. 5 ft 6 in tall and only 108 lb. Not diabetic. Cardiologist told me since it is familial that diet won't fix it. Wants me on meds.

  • @Manyroadsnorules
    @Manyroadsnorules 5 หลายเดือนก่อน +1

    Thank you!! Great information!

  • @domgreco7
    @domgreco7 ปีที่แล้ว +1

    Thank you. Great info.

  • @zedgarden
    @zedgarden หลายเดือนก่อน

    Best video ever. Watched it at least 5 times. Thank you!

  • @C02045
    @C02045 23 วันที่ผ่านมา

    Phenomenal quality advice. From a Master!

  • @cosmicviewer477
    @cosmicviewer477 ปีที่แล้ว +3

    I could listen to this doctor all day. He makes this so interesting. I bet at some point he was an educator/teaching doctor/trainer.

  • @peter1835
    @peter1835 4 หลายเดือนก่อน +1

    I have been binge watching this subject for months due to having gallbladder attacks which i think is linked to having high cholesterol (had other symptoms which are slowly disappearing over the past 6 months due to a very low cholesterol diet). I wish I had seen this video months ago best explanation I have seen by miles!!!

  • @SiriusStarGazer
    @SiriusStarGazer 4 หลายเดือนก่อน +1

    wow. I was spell bound by this doctor's presentation. I mean I have been over indulging in your videos this last past week. Can't get enough, Hope that over indulgence doesn't cause a rise in cholesterol. lol

  • @JimLove1
    @JimLove1 8 หลายเดือนก่อน +1

    I cannot believe it took me so long to get your videos suggested to me. Maybe they have improved the algorithm!

  • @esotericsolitaire
    @esotericsolitaire 7 หลายเดือนก่อน +1

    Wonderful explanation!

  • @RiDankulous
    @RiDankulous ปีที่แล้ว +1

    You have good information! The confidence I can have in the information is higher due to less bias and more objective analysis of information used by others.