Thank u sir for helping me a lot.. I'm doing bsc in zoology and I don't think that there is any topic left in my syllabus that haven't been seen in ur video.. Thank you so much...
Your presentation is good, I like it. However, small correction for you is RAS is inactive when bound to GDP and active when it's bound to GTP. You have mentioned that RAS is inactive when GDP is disconnected...that's not the case...
You are saying that upon activation GTP hydrolyse to GDP as KRAS is GTPase. It is wrong. Actually on activation GDP to GTP bound state and on inactivation GAP play role to hydrolyse GTP to GDP state. See your video from time 5:50 to onward
Hi can you help me to understand about inhibitor Thank you Im from iran and i cant acces to information for end my article Please help me because no persian for get this video
ur videos are really helpful my final exams is coming next week and I hate it to learn through books. Beside that I wanted to ask if I could ask some questions about some typical tasks for my final exam. I hope u can respond me...
I am researching at what amino acid position is the 4th domain of the activate in which the GAP protein usually hydrolyzes the gamma phosphate on the RAS protein. Anyone have any ideas?
The writings which are scrolling at base of your vdo .. the technical terms are mistakenly written. It must be written by some non technical persons.. Your teaching is extremely good.. the vdo s are really helpful.
You've done a great job to help break thru a very complicated concept. Thank you!
Thank you so much for appreciating my efforts
seriously man!! any topic i search for, you have a video for it .. very helpful
great video, made such complex processes easy to understand! Thank you!!
You're welcome
How old are you man.. Your effort is nice ..
Thank u sir for helping me a lot.. I'm doing bsc in zoology and I don't think that there is any topic left in my syllabus that haven't been seen in ur video.. Thank you so much...
Grateful for Your Explanation, Thank you so much
You're welcome
Excellent description of KRAS!
Thank you
THANK U´SO SO SO MUCH!! Such an excellent and simple explanation, it´s really what I need for my presentation tomorrow!!! New subs here
Thank you for your support
Thank You Sir, you explanation is just amazing.
Thabk you
You are and incredible teacher!!
Thank you
A young Shomu. He's been puttin in work forever
Thank you so much for appreciating my efforts
@@shomusbiologyofficial I wish you nothing but continued success. You deserve it!
this is awesome! but i'm missing the intro song!
great work Shomu, thx for sharing your understanding!
You're welcome. Glad to hear that you're getting benefit from my lectures
You really simplifyed that man!! thank you!
Thank you❣
You're welcome
Very helpful ❤
Thank you
Awesome sir... U are really talented... Sir please all time of transcription video dao
Thank you. Glad you liked my lectures
these videos are brill. so helpful
Thank you Sir 🙏
You're welcome
Thank you so much king🙏
You're welcome
Thank you. Pls don't stop. it's really helpful
This was a very informative lecture. Thank you.
There is a mistake at 5:44. Upon Ras activation GDP becomes GTP. Not other way around
Ras is activated when attached with gtp
Your presentation is good, I like it. However, small correction for you is RAS is inactive when bound to GDP and active when it's bound to GTP. You have mentioned that RAS is inactive when GDP is disconnected...that's not the case...
Did I. Should not say that
thank you its really helpful now i could understand the concept more clearly than uworld explanation
You are saying that upon activation GTP hydrolyse to GDP as KRAS is GTPase. It is wrong. Actually on activation GDP to GTP bound state and on inactivation GAP play role to hydrolyse GTP to GDP state. See your video from time 5:50 to onward
that was a great video. thank you
You're welcome
very nice Shomu, r you doing PhD !,
thank you so much, very helpful
You're welcome
Very informative lecture Sir!
Thank you :)
You're welcome
You are amazing! Thank You!
You're welcome
What is the kras nras braf
U save my ilfe !!!! thank u thank u!!
All the way from Republic of Ireland filipino
Thank you
Hi can you help me to understand about inhibitor
Thank you
Im from iran and i cant acces to information for end
my article
Please help me because no persian for get this video
thank you for your effort !
Super helpful!!! THANK YOU
How do free radicals activate the MAPK (sos/ras/raf/MEK/ERK) ?
ur videos are really helpful my final exams is coming next week and I hate it to learn through books. Beside that I wanted to ask if I could ask some questions about some typical tasks for my final exam. I hope u can respond me...
omg so clear thanks
You're welcome
I need same help
I am researching at what amino acid position is the 4th domain of the activate in which the GAP protein usually hydrolyzes the gamma phosphate on the RAS protein. Anyone have any ideas?
is there any video of pdgf
Thanks Sir.
Keep it up man.....nice job
bro how does this inactivate tumour suppressors like p53? is there a video on that?
Thank you so much for this:)
Thank you sooooooo much
😊
nice explanation...
My friend u r genius
thank u .. very helpful
This is treatble or not
Is there a way of treating a mutated KRas gene or recognising that it is mutated.
Sequenceing kras test
Is this ras??
it's GDP to GTP 5:48. Come on man, so many newbies rely on your videos. Please review the content before uploading it !!
+rajesh pal sorry for the mistake. But we will fix as soon as anyone reports.
Tq
You're welcome
In which chromosome is KRAS gene ?
Icar net m important topic recommend Kar dijiye
Sir,
I promote EGF can you tell me that excess EGF causes tumor? I want to sell EGF to doctors. Can you help me in this aspect
Thankyouu
👍👍👍👍
Thank you
Mene ct scan krwaya tha 9 msv ka
RAS is not going to bind directly with RTK`s cellular portion, GRB2 and Shc proteins are involved in RAS activation.
+M Ahmad right. Sh2 domain protein needs to interact
The writings coming are wrong.. like KRas is said chaos
Where?
The writings which are scrolling at base of your vdo .. the technical terms are mistakenly written. It must be written by some non technical persons..
Your teaching is extremely good.. the vdo s are really helpful.
highlight bom