Lecture 1-Spongiotic Dermatitis

[@draalrfai]

0:50 Case 1 --> Spongiotic Dermatitis reaction pattern -- 4:25 slide of acute phase with vesiculation. 5:36 slide of sub-acute phase. 6:58 slide of chronic phase.
9:00 ICD
10:00 Dyshidrotic eczema
10:41 Seborrhic Dermatitis
11:58 Stasis Dermatitis
13:40 Pityriasis Rosea
15:17 Polymorphic Eruption of Pregnancy
16:34 Mycosis Fungoides
17:47 Summary with Clues
18:19 slides of fungal infection (TV) as ddx
19:19 Dermatophytosis with PAS stain
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[@kicsihouse]

thank you very much for this serie, highly appreciated!

[@imagedoctor]

amazing lecture.. please upload some more lectures.. appreciated much.

[@kazumithumargondalia9171]

Reading a Sternberg and hearing you is a kind of whole meal to me.. thank you so much for this

[@olivialai7712]

Thank you for teaching us during quarantine! It's really very much appreciated.

[@ABC-fv7ow]

Great 👍

[@omerali2690]

Thanks a lot sir. Can you please start a series on neoplastic dermatopathology?

[@mariafernandatorresbueno484]

Thank you so much, Dr.!

[@ncorry8491]

@ Case 1 -> Spongiotic Dermatitis reaction pattern - @ slide of acute phase with vesiculation. @ slide of sub-acute phase. @ slide of chronic phase.
intraepidermal edema with clear spaces separating keratinocytes
Acute: also perivascular lymphocytic infiltrates in upper dermis, lymphocyte exocytosis
Subacute: focal parakeratosis, acanthosis, papillomatosis, eosinophils
Chronic: prominent parakeratosis, acanthosis, papillomatosis; may have minimal spongiosis; fibroplasia of papillary and upper reticular dermis; variable inflammatory infiltrate
Different types of eczema
1. Allergic contact dermatitis 2. Irritant contact dermatitis 3, Numular eczema 4, Dyshidrotic eczema (hands and feet only) 5. Atopic dermatitis (children) 6. Id reaction ( in response to a separate rash) 7 Seborrhic Dermatitis
@ ICD - irritant contact dermatitis --- A little necorsis, spongiosis more in superficial epidemris, numerous admixed neuts
@ Dyshidrotic eczema - acral site bx, vesiculation , spongiotic changes
@ Seborrhic Dermatitis ---Parafollicular Parakeratosis in association with hair follicle
Other things to consider:
1.Stasis Dermatitis 2.Pityriasis Rosea 3. Polymorphic Eruption of Pregnancy 4.Mycosis Fungoides 6. Always do a PAS tor rule out fungal infection
@ Stasis Dermatitis
Lower leg, mild spongiosis , dilated vessels with thickend walls, haemosiderin deposiyion , a lobular proliferation of vessels
Characterstic lobular pattern of superficial and deep dermal neovascularization with dermal fibrosis, perivascular lymphocytic infiltrates, histiocytes and variable number of plasma cells, extravasated erythrocytes and hemosiderin laden macrophages
Hyperplasia of endothelial cells
Variable acanthosis and hyperkeratosis
​@ Pityriasis Rosea
Non-specific subacute or chronic dermatitis with focal hyperkeratosis and angulated mounds of parakeratosis with slight acanthosis
Granular cell layer is absent beneath the foci of parakeratosis
Intraepidermal cytoid body may be present
Focal acantholytic dyskeratosis occasionally documented
Also lymphohistiocytic infiltrate around vessels of superficial plexus and slight spongiosis
Occasionally scattered eosinophils and erythrocytes within epidermis
@ Polymorphic Eruption of Pregnancy
@ Mycosis Fungoides
@ Summary with Clues
@ slides of fungal infection (TV) as ddx
@ Dermatophytosis with PAS stain

[@ilariascandagli3975]

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[@muslimalhamdulillah3739]

Thank you

[@ncorry8491]

Thanks great resource

[@sachinchaudhari2343]

Hi. What is pompholyx

[@butcherbutcherovich6470]

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