Our New USMLE Telegram group (link valid at least at time of this clip): t.me/+mSDYK3fV2wdkNmY0 Instagram: instagram.com/mehlman_medical/ Mehlman HY Heme/Onc PDF: mehlmanmedical.com/hy-heme-onc/
Nope. Schistocytes occurs when the RBCs get sheared as they flow by a microthrombi or a prosthetic valve. In G6PD you’ll get a bite cell rbc(cell literally looks like it got hole punched on its edge) caused by macrophages consuming the precipitated hemoglobin on its surface (Heinz bodies)
It doesn't. I said most common cause of AR for USMLE is aortic dissection, where there's aortic root dilatation secondary to retrograde propagation toward the aortic root. In this patient, the incompetence of the prosthetic valve is causing AR, as evidenced by the massive pulse pressure (diastolic = palpable = "zero"). Prosthetic valves can cause shearing forces on RBCs leading to schistocytosis.
Our New USMLE Telegram group (link valid at least at time of this clip): t.me/+mSDYK3fV2wdkNmY0
Instagram: instagram.com/mehlman_medical/
Mehlman HY Heme/Onc PDF: mehlmanmedical.com/hy-heme-onc/
You just summed up 70% of Pathology in a single Q.
i love heme. Macroangiopathic hemolytic anemia easy q. Thanks mike
The value I got from this 9 minute clip is immeasurable
An excellent coverage
Weird factoid for pressure reading "palpable " refer to no diastolic heard ,, first time i know a bout it .. thanks mike for clearing this out
You are a great teacher🙏👍🏻👍🏻👍🏻👍🏻👍🏻👍🏻.
you are marvellous, never forget that
❤❤❤
high quality wow
Good one! Thank you!
why I can't enter in the group? telegram.
Maybe u were banned for spam
Thank you so much, super.
Dont we see schistocytes in g6pd when hemolysis happens?
Nope. Schistocytes occurs when the RBCs get sheared as they flow by a microthrombi or a prosthetic valve. In G6PD you’ll get a bite cell rbc(cell literally looks like it got hole punched on its edge) caused by macrophages consuming the precipitated hemoglobin on its surface (Heinz bodies)
@@ill-swey5942 noice so macrophages know how to bite with a clean cut not to blow the whole cell.
hey mike what does rbc shearing have to do with aortic root dilation and regurg? coincidental? this poor sucker has both?
It doesn't. I said most common cause of AR for USMLE is aortic dissection, where there's aortic root dilatation secondary to retrograde propagation toward the aortic root. In this patient, the incompetence of the prosthetic valve is causing AR, as evidenced by the massive pulse pressure (diastolic = palpable = "zero"). Prosthetic valves can cause shearing forces on RBCs leading to schistocytosis.
But it’s the mitral valve that’s incompetent, like how does that mess with the aortic valve
Also thanks man 👍🏽
@@imanaidid3753 Same question :(
i came 5 hour late ):
ACE ......