My email newsletter gets you up to date research and practical diet tips plus discounts on products, as a thank you for joining my newsletter here is a FREE Intermittent Fasting Meal Plan (downloadable): thomasdelauer.lpages.co/fastandfeast/ or a FREE Keto Meal Plan (downloadable): thomasdelauer.lpages.co/real-person-keto/
*Video topic suggestion* Hi Thomas! I have fat malabsorbtion and I've tried almost everything under the sun to alleviate the symptoms But nothing seems to work. I was doing keto for about 1,5y and really loved it (alot of fasting made it doable..) since then I've tried to cycle keto But I just can't stand being bloated with aches and pain. Would you consider to make a video of how to manage the keto diet with impaired fat absorbtion? Thanks for the great content. Sincerely
Hey Thomas currently I'm on day number six of my water fast. I'm 215 my highschool weight was 165 I'm not necessarily trying to get back to it but I was curious of what you think should be the longest I fast. Quite honestly I'm feeling really good right now.👍✌️❤️😀
Everytime I am feeling myself fail in my fast I come to you and Dr. Berg and you remind me and teach me what I need to keep going. Thank you Thomas, for investing in our health so freely and encouraging us with every video. 🙏🏽🇿🇦🙌🏾
A tip on a totally different topic. Lots of people use canned beans but they have trouble digesting them because of the lectins in the beans. Soaking them overnight is a great way to reduce lectins (these cause bloating and gas) but pressure cooking them after soaking also reduces a lot of the lectins. If you don't want to do that the only brand of canned beans that are presoaked and pressure cooked before canning are Eden beans.
All canned beans are soaked. If they weren't so many people would be hospitilized. It's beans in bags or sacks that need to be pressure coaked or pre soaked.
I stopped drinking coffee for breakfast after my fast to switch to ceremonial matcha. I just wanted to reduce insulin and prevent it from a spike after a long fast. Have been doing matcha for 2 decades, daily. May be that's the reason my weight staying consistently stable over the years, no matter what are my diets. I believe there are a lot of things we can do to activate autophagy if we combine what we eat, daily activities and some good proper techniques like fasting and fitness goals. There is always a combination of many things to get results. I experienced different ways to bring down my blglucose (was prediabetes, insulin resistant for 20 years without knowing). I finally found that fasting alone, or only exercising even tremendously, or just following a strict diet won't really work. Many other people shared the same frustration when they could not get good results by doing specifically certain things to resolve their problem. Drinking matcha daily helps me to stay well the past many many years. Adding turmeric, cinnamon, cardamon and other healthy herbs didn't save me from insulin resistant. Exercise on machine and daily long hours walk didn't bring my blood glucose to normal. I finally realized all of this have to combine together with consistency, daily and the most important are to educate and discipline yourself on a long journey. Simple but requires patience, knowledge and discipline.
What kind of matcha do you use? I got some cerremonial but it was pretty expensive. like 28 for a small tin and it also contained a lead warning. I got it from whole foods.
I love that this discusses the similarity between exercise and fasting regarding AMPK activation. Having learned so much about my body through fasting, when it comes to exercise and glycogen depletion (among other energy draining processes), I've come to understand how it *FEELS* to be low on energy reserves. Before fasting, I had little to no idea what the causes of tingling sensations or cramps or foggy brain or any other symptoms of energy systems imbalance (be it low ATP, low glycogen in the arms or legs, out-of-balance electrolytes, etc.). Fasting trains you how to know the difference. You learn about your body and brain's needs for electrolyte balance - from fatigue and foggy brain all the way to heartbeat irregularities. You learn how it feels to be TRULY hungry and TRULY depleted of glycogen (like near end-of-marathon runner extremes depending on how hard you exercise and how deeply into a long-term fast you do so). You learn about nutrient timing and insulin system manipulation/control... And possibly most important of all... you learn about gut microbiome health and how that relates to things like immune system health, chronic diseases, and mental health as well. It really is a miracle... fasting. I can't think of another way to describe it.
Yes, I feel woozy and tingly on a water fast at day 2 and increase electrolytes because that uh-oh feeling tells me my electrolytes are off. But then the mean ghrelin aka gremlin starts up and I have to keep busy. I am not really a fan of the dizzy woozy feeling though. Having been keto a while I thought it would not be as bad. I keep waiting for that great, energetic, brain energy feeling to kick in. Not here yet. 🤔
@@catcan221 Personally I stopped noticing hunger and stopped having cravings around day 3 at about 60 hours after eating my last calorie on day zero. Of course, the hunger was still there around breakfast, lunch, and dinner times... but it was far less noticeable and using a "caffeine hack" would essentially negate it all together, rather than just dulling it till it passed. I haven't done a long-term (more than 48 hours) fast in I think over 2 years though, haven't really felt the need to and don't want to strip down my body again... but the long ones I did (a 7-day, 4 separate 5-day fasts across a 3 year span) were very, VERY helpful with recomposition of my body and repairing and resetting my gut microbiome! ❤❤
@@oohwha I did 72 hours for the first time. I am only about 15 pounds off my target weight so this is partly to break the plateau and also for autophagy as I am in my 50s and really want to clean up senescent cells. My mom was just diagnosed with cancer and it makes me realize that even when we think we are doing all the healthy things, we can still have bad cells lurking in us. I never felt the "amazing energy and clarity" some say they get. I also felt ebb and flow of the hunger pangs. Having been ketovore 5 months and doing TRE, I felt I should be able to try a longer fast. Now refeeding slowly. Started with a cup of bone broth. Two hours later a single egg. Then three hours later some oven cooked wild caught salmon. I was not sure I wanted beef the first day back. Hoping that doing a 3 day every couple months will be good for both weight loss and autophagy. 👍🏻
@@catcan221 sounds like you've got a solid plan! Like you, I wanted the autophagy boost as well. For the first 3 days of fasting, your metabolism boosts a bit before things "slow down" as you become fueled almost exclusively by ketones... although, in your case, you are *ALREADY* fueled mostly by ketones already :) Sounds like you have an excellent refeeding strategy as well. Doing a 3-day fast every couple of months would definitely be a great way to keep will power and discipline well-trained while also helping you ramp up AMPK and increase fatty acid mobilization even MORE than with Keto alone. If I were still trying to lose a large amount of weight, I would likely still be doing longer term fasting as well (my first 5-day fast I worked out every day and dropped 20 pounds from 201 to 181 so when I started refeeding I only gained back 10 pounds and kept the 190 weight). Good luck with your goals, your plan is solid and the results will definitely come. I personally found I had to start tracking my calories in and calories burned every day to really zero in on that last bit of weight management (I fluctuate between 185 and 195 right now, for the past 2 years). I can really focus my calories toward healthy fats and toward micronutrients (mostly from seeds and nuts that are high in calories) so that I *FEEL* like a million bucks every day. When I blindly ate and worked out, I was off my game some days with no energy... likely due to not enough magnesium or maybe vitamin D... but tracking calories allows me to go all in on things like eggs, salmon, sardines, olive oil, macadamia nuts, sprouted pumpkin seeds, and complex carbs I need after a day doing deadlifts or squats at the gym. Calorie counting is easy enough with apps like the Fitbit premium plan includes... just scan the bar code and put in the amount you ate. A kitchen scale that measures by the gram is a game-changer as well. Probably the best $10 I ever spent on my health in my life! 😂😂💪💪
EXCELLENT video! I finally understand how ampk and mtor work!! By the way, “exacerbated” is used only in the context of something bad increasing. Thanks again. I watch pretty much ALL of your videos that pop up in my feed.
Some of us are here to simply increase our biochem terms and words, sometimes I like to hear him talk for a while just to pick up a new word or two or concept instead of fast answers. But to each their own
Thank you Thomas! Your info has been very helpful for me. Ignore the critics below. They likely haven't helped people on the level you do daily. In my book, that's "proof". Bless up & keep up the good work.
One more question for you . I’ve developed gut challenges, chronic pain etc.. as I’ve aged and this is another reason I’ve chosen to get back into water fasting. Do you have any talks/videos/teaching regarding SIBO or other types of GI challenges (IBS) Much appreciation for you sharing your knowledge 🙏
Thank you Thomas! You have the most wonderful way of explaining things. I know you have said often 1 calorie will break a fast, but this really explains the how/why. With that knowledge it is much easier to follow a fasting regimen as we know what we are really doing! Keep up your great work!
1 calorie, not that much, obviously the body is still is empty and a calorie isn't going to make much difference and if so then not for that long before your back in that state anyway
wait a minute... in some of your vids you promote the use of the electrolyte supplement, LMNT for use while intermittent fasting which has not 1 but 10 calories per serving! Which is it???
Very interesting points. I felt like the domino analogy was a bit confusing as it seemed to imply that ingesting a single calorie would completely reset the "momentum" of autophagy to zero, the same as if you ate a three-course meal. This would then contradict the point about gluconeogenesis later, which doesn't reset AMPK and autophagy to zero but stabilises AMPK (at a much higher level than it would be when in a fed state, presumably). So I'd still like to know: 1) What's the minimum food intake that sets us to a "fed" state and resets autophagy to baseline levels? 2) If we eat less than that (e.g. tea with milk, or even a single grain of rice?), how much is autophagy reduced, and how long before it regains the momentum it previously had? 3) How long before you "max out" and AMPK levels stabilise? I'd read a paper before suggesting that autophagy rate continues to rise for maybe 5 or 6 days before stabilising, perhaps even implying that autophagy from a one- or even two-day fast is almost negligible. What's the actual situation?
Very good questions. IDK if anyone has answers. "it seemed to imply that ingesting a single calorie would completely reset the "momentum" of autophagy to zero" -- I find this quite implausible. A SINGLE calorie? No. Fifty calories maybe. There's nothing magical about an ingested calorie versus a calorie from something endogenous. The body is constantly turning over materials (proteins, lipids, etc.), recycling them in part, converting to glucose or ketones and burning them for energy, and so on, and that holds true during a fast no less than at other times (and perhaps *more* than at other times). IOW, there are ALWAYS calories floating around. Is an exogenous molecule somehow labeled "EXOGENOUS MOLECULE! TREAT THIS DIFFERENTLY!", versus an unlabeled endogenous molecule? No, of course not. I get than any significant quantity of, say, exogenous carbohydrate could interrupt autophagy, at least for a time. Perhaps 10 grams would do it, although not for long. How long does it take to burn 40 calories worth of carb when you are fasting? An hour? How long could autophagy possibly be inhibited? Two hours, maybe? IDK, I am just thinking aloud, and reasoning as best I can.
This is the golden question no one seems to have a definitive answer for. For now I will continue consuming the roughly 15-30 calories of creamer in my iced coffee every morning since I don't FEEL like it interrupts my fasts to a significant degree.
Very good information! I started water fasting years ago as fasting always gave me emotional and mental strength and helped to ground me. I eventually got out of fasting and now 10-15 years later I am water fasting again. This time I’m learning what is going on within the body as I fast. I’m learning that many people water fast but include tea and coffee, cream etc while fasting. I thought then you’re not in a true absolute fast (I wasn’t referring to autophagy as for me personally fasting was for “greater” purposes. Well now I’m learning about this amazing word and my body how it all works so Im so on board with fasting for several reasons including autophagy ☺️ My question is are you recommending the Organifi red juice during the fasting state or at the beginning of breaking the fast? Sorry if you already explained this in the video explains this . I’ve listened to it 3 times. Trying to learn. Much appreciation 👍🏼🌻
I'm type 1 diabetic and need insulin around the clock because glucose is always being released from glycogen stores long after glucogenis has ceased and liver is expelled stores during fasting. Since there's always glucose which are calories in bloodstream why would one calorie make a difference 🤔
Great video. Your video's are super informative. I have been doing this all wrong. You have a really good way of breaking down some really wonky topics! thank you
36 hours into my last fast I felt so much energy I went outside n ran 2 miles, I’ll keep it to 1 mile next time since I felt muscle fatigue as if I ran 5 miles but thats was a shocker that I went from weak n starving to death, to feeling energetic
There seems to be a controversy regarding autophagy as it takes 4 days on average to deplete liver of fuel. Why would autophagy begin before this depletion occurs.
The calories thing is overblown and made confusing by influencers so they can get you to click on every video they create and keep you confused. A few calories for instance from something like a magnesium supplement or pomegranate extract in a pill supplement won’t stop autophagy just like coffee, which has 5-10 calories per serving won’t. Food will, like actual food and gum with sugars in it, otherwise no. Enough hand wringing
Did you ever find an answer? I ate a small piece of bread to be polite to an old lady, maybe 30 calories. Would love to know how long before autophagy kicks back in. By the way, I was 50 hours in to a fast.
I've read that coffee will actually elevate glucose levels in some people. I'm just playing it safe and drinking only water with electrolytes during my 3-day fast.
Love the analogies! Makes it easy to understand the process going on during a fast & laugh at myself as i remember the "troll" guarding the bridges if I have some weakness & feel like breaking my fast! No way buddy troll, no calories for you! Thanks again for your sharing all your knowledge Thomas :)
Hello. I have been having a problem of indigestion, constipation and obesity. I started fasting in 2021 and everything went away. My fasting ranges from 18:6 fasting to I meal a day (OMAD). The problem is that I am now having problems of indigestion and constipation again and weight loss has stagnated
How does lemon juice affect a fast? And when you say "creamer" are you talking "heavy whipping cream"? Or that sugary stuff that office coffee centers keep on hand?
Thanks Tom well guess no more creamer mushroom coffee i will drink this during a meal instead, i still drink green tea and also take ACV during the fast and lots of water with ice
My email newsletter gets you up to date research and practical diet tips plus discounts on products, as a thank you for joining my newsletter here is a FREE Intermittent Fasting Meal Plan (downloadable): thomasdelauer.lpages.co/fastandfeast/ or a
FREE Keto Meal Plan (downloadable): thomasdelauer.lpages.co/real-person-keto/
Hello papa
*Video topic suggestion* Hi Thomas! I have fat malabsorbtion and I've tried almost everything under the sun to alleviate the symptoms But nothing seems to work. I was doing keto for about 1,5y and really loved it (alot of fasting made it doable..) since then I've tried to cycle keto But I just can't stand being bloated with aches and pain. Would you consider to make a video of how to manage the keto diet with impaired fat absorbtion? Thanks for the great content. Sincerely
Hey Thomas currently I'm on day number six of my water fast. I'm 215 my highschool weight was 165 I'm not necessarily trying to get back to it but I was curious of what you think should be the longest I fast. Quite honestly I'm feeling really good right now.👍✌️❤️😀
What about black tea? I really like it better.
So no black coffee?
Everytime I am feeling myself fail in my fast I come to you and Dr. Berg and you remind me and teach me what I need to keep going. Thank you Thomas, for investing in our health so freely and encouraging us with every video. 🙏🏽🇿🇦🙌🏾
Check out Dr. Rhonda Patrick
"Dr." Berg???
Check our Dr Eric Berg. I check out his content all the time, super informative.
@@firemelon7296 He is not wrong about everything but he's not an MD and a lot of his info is pure nonsense. He just needs to keep funding Scientology!
@@poulwinther what, really?
Fasting is a way of life!💯
Reel Meelad. Yes. Fasting and eating. 2 sides of a coin. Its binary. 👍
Amen brutha!
Your right, but philosophical bullshit.
When I don't eat at work the 300lb coworker of mine said that's not good 🙄🙄🙄 yuuuuuppp I say lol most really don't know
Nice to know there's a positive to not being able to afford food.
A tip on a totally different topic. Lots of people use canned beans but they have trouble digesting them because of the lectins in the beans. Soaking them overnight is a great way to reduce lectins (these cause bloating and gas) but pressure cooking them after soaking also reduces a lot of the lectins. If you don't want to do that the only brand of canned beans that are presoaked and pressure cooked before canning are Eden beans.
Soak with a teaspoon of baking soda.
Don't they use young (not fully mature) beans, though? These have less lectins.
Jovial brand beans are also pressure cooked
All canned beans are soaked. If they weren't so many people would be hospitilized. It's beans in bags or sacks that need to be pressure coaked or pre soaked.
Outstanding. Thank you
I stopped drinking coffee for breakfast after my fast to switch to ceremonial matcha. I just wanted to reduce insulin and prevent it from a spike after a long fast. Have been doing matcha for 2 decades, daily. May be that's the reason my weight staying consistently stable over the years, no matter what are my diets. I believe there are a lot of things we can do to activate autophagy if we combine what we eat, daily activities and some good proper techniques like fasting and fitness goals. There is always a combination of many things to get results. I experienced different ways to bring down my blglucose (was prediabetes, insulin resistant for 20 years without knowing). I finally found that fasting alone, or only exercising even tremendously, or just following a strict diet won't really work. Many other people shared the same frustration when they could not get good results by doing specifically certain things to resolve their problem. Drinking matcha daily helps me to stay well the past many many years. Adding turmeric, cinnamon, cardamon and other healthy herbs didn't save me from insulin resistant. Exercise on machine and daily long hours walk didn't bring my blood glucose to normal. I finally realized all of this have to combine together with consistency, daily and the most important are to educate and discipline yourself on a long journey.
Simple but requires patience, knowledge and discipline.
What kind of matcha do you use? I got some cerremonial but it was pretty expensive. like 28 for a small tin and it also contained a lead warning. I got it from whole foods.
I surf for 3-4hrs a few times a week fasted. Works amazing.
I love that this discusses the similarity between exercise and fasting regarding AMPK activation.
Having learned so much about my body through fasting, when it comes to exercise and glycogen depletion (among other energy draining processes), I've come to understand how it *FEELS* to be low on energy reserves.
Before fasting, I had little to no idea what the causes of tingling sensations or cramps or foggy brain or any other symptoms of energy systems imbalance (be it low ATP, low glycogen in the arms or legs, out-of-balance electrolytes, etc.).
Fasting trains you how to know the difference. You learn about your body and brain's needs for electrolyte balance - from fatigue and foggy brain all the way to heartbeat irregularities. You learn how it feels to be TRULY hungry and TRULY depleted of glycogen (like near end-of-marathon runner extremes depending on how hard you exercise and how deeply into a long-term fast you do so). You learn about nutrient timing and insulin system manipulation/control...
And possibly most important of all... you learn about gut microbiome health and how that relates to things like immune system health, chronic diseases, and mental health as well.
It really is a miracle... fasting. I can't think of another way to describe it.
What type of fasting? The types work in different ways.
Yes, I feel woozy and tingly on a water fast at day 2 and increase electrolytes because that uh-oh feeling tells me my electrolytes are off. But then the mean ghrelin aka gremlin starts up and I have to keep busy.
I am not really a fan of the dizzy woozy feeling though. Having been keto a while I thought it would not be as bad. I keep waiting for that great, energetic, brain energy feeling to kick in. Not here yet. 🤔
@@catcan221 Personally I stopped noticing hunger and stopped having cravings around day 3 at about 60 hours after eating my last calorie on day zero.
Of course, the hunger was still there around breakfast, lunch, and dinner times... but it was far less noticeable and using a "caffeine hack" would essentially negate it all together, rather than just dulling it till it passed.
I haven't done a long-term (more than 48 hours) fast in I think over 2 years though, haven't really felt the need to and don't want to strip down my body again... but the long ones I did (a 7-day, 4 separate 5-day fasts across a 3 year span) were very, VERY helpful with recomposition of my body and repairing and resetting my gut microbiome! ❤❤
@@oohwha I did 72 hours for the first time. I am only about 15 pounds off my target weight so this is partly to break the plateau and also for autophagy as I am in my 50s and really want to clean up senescent cells. My mom was just diagnosed with cancer and it makes me realize that even when we think we are doing all the healthy things, we can still have bad cells lurking in us.
I never felt the "amazing energy and clarity" some say they get. I also felt ebb and flow of the hunger pangs. Having been ketovore 5 months and doing TRE, I felt I should be able to try a longer fast.
Now refeeding slowly. Started with a cup of bone broth. Two hours later a single egg. Then three hours later some oven cooked wild caught salmon. I was not sure I wanted beef the first day back. Hoping that doing a 3 day every couple months will be good for both weight loss and autophagy. 👍🏻
@@catcan221 sounds like you've got a solid plan!
Like you, I wanted the autophagy boost as well. For the first 3 days of fasting, your metabolism boosts a bit before things "slow down" as you become fueled almost exclusively by ketones... although, in your case, you are *ALREADY* fueled mostly by ketones already :)
Sounds like you have an excellent refeeding strategy as well. Doing a 3-day fast every couple of months would definitely be a great way to keep will power and discipline well-trained while also helping you ramp up AMPK and increase fatty acid mobilization even MORE than with Keto alone.
If I were still trying to lose a large amount of weight, I would likely still be doing longer term fasting as well (my first 5-day fast I worked out every day and dropped 20 pounds from 201 to 181 so when I started refeeding I only gained back 10 pounds and kept the 190 weight).
Good luck with your goals, your plan is solid and the results will definitely come. I personally found I had to start tracking my calories in and calories burned every day to really zero in on that last bit of weight management (I fluctuate between 185 and 195 right now, for the past 2 years). I can really focus my calories toward healthy fats and toward micronutrients (mostly from seeds and nuts that are high in calories) so that I *FEEL* like a million bucks every day. When I blindly ate and worked out, I was off my game some days with no energy... likely due to not enough magnesium or maybe vitamin D... but tracking calories allows me to go all in on things like eggs, salmon, sardines, olive oil, macadamia nuts, sprouted pumpkin seeds, and complex carbs I need after a day doing deadlifts or squats at the gym.
Calorie counting is easy enough with apps like the Fitbit premium plan includes... just scan the bar code and put in the amount you ate. A kitchen scale that measures by the gram is a game-changer as well. Probably the best $10 I ever spent on my health in my life! 😂😂💪💪
EXCELLENT video! I finally understand how ampk and mtor work!! By the way, “exacerbated” is used only in the context of something bad increasing. Thanks again. I watch pretty much ALL of your videos that pop up in my feed.
Couldn't have said it better myself... autophagy IS the promise land! I strive every day to trigger it. Great video and insight!
the guy needed 10 minutes to tell you that cream in your coffee has calories ... genius !
Thank u for saving my time
Thank you as well. It's like a filler episode.
Some of us are here to simply increase our biochem terms and words, sometimes I like to hear him talk for a while just to pick up a new word or two or concept instead of fast answers. But to each their own
@@serbannicolau3489 To be fair, when you’re compelled to pump out a 10 minute video every day, 90% of the content is going to be filler.
Thank u.
Thank you Thomas! Your info has been very helpful for me. Ignore the critics below. They likely haven't helped people on the level you do daily. In my book, that's "proof".
Bless up & keep up the good work.
This is a superb explanation of how fasting and autophagy works.
Thank god for coffee, acv, and green tea!!!
One more question for you .
I’ve developed gut challenges, chronic pain etc.. as I’ve aged and this is another reason I’ve chosen to get back into water fasting.
Do you have any talks/videos/teaching regarding SIBO or other types of GI challenges (IBS)
Much appreciation for you sharing your knowledge 🙏
Thank yoy for touching on the green tea, coffee, and ACV. Those are my go to fluids to break the boredom only water.
Update.... 46 LBS in 4 months on week 15 of 5 days fasting!!
Are you saying you fast 5 days straight out of 7 for the last 15 weeks? If so, that is some awesome dedication. I seldom make it 3 consecutive days.
Well done 🏆🏆🏆
@CC thx it's 58 now almost to goal
Day 8 on my 16-8 fasting with Whole Foods. So far I am down 11 pounds.
Keep going good work
5day water fast feels amazing !!!! i may go for day 6 :D cheers!
That's what I do!!! 9the week of 5 days
Do you not hit hunger at all?
Right!! That's what I do!! Eat food and gain even low carb it's crazy
@@KingsDaughter. sometimes but I drink more water and if really hungry I drink both
@@tanyaa2327 thank you, you mean broth?
Thank you Thomas! You have the most wonderful way of explaining things. I know you have said often 1 calorie will break a fast, but this really explains the how/why. With that knowledge it is much easier to follow a fasting regimen as we know what we are really doing! Keep up your great work!
1 calorie, not that much, obviously the body is still is empty and a calorie isn't going to make much difference and if so then not for that long before your back in that state anyway
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Interesting, great vid. I was wondering MCTs have an effect on autophagy ?
One of the first here 💪🏻
Brilliant info Thomas ! 👌
Will Apple cider vinegar, Himalayan salt, and cream of tartar affect the fast and stop autophagy
Nice analogy w/ the bridge-builder vs. the garden trimmers. Very memorable. Thanks!
i'm glad you answered the black coffee question i had because idk if i can fast without it lol
wait a minute... in some of your vids you promote the use of the electrolyte supplement, LMNT for use while intermittent fasting which has not 1 but 10 calories per serving! Which is it???
Very interesting points. I felt like the domino analogy was a bit confusing as it seemed to imply that ingesting a single calorie would completely reset the "momentum" of autophagy to zero, the same as if you ate a three-course meal. This would then contradict the point about gluconeogenesis later, which doesn't reset AMPK and autophagy to zero but stabilises AMPK (at a much higher level than it would be when in a fed state, presumably).
So I'd still like to know: 1) What's the minimum food intake that sets us to a "fed" state and resets autophagy to baseline levels? 2) If we eat less than that (e.g. tea with milk, or even a single grain of rice?), how much is autophagy reduced, and how long before it regains the momentum it previously had? 3) How long before you "max out" and AMPK levels stabilise? I'd read a paper before suggesting that autophagy rate continues to rise for maybe 5 or 6 days before stabilising, perhaps even implying that autophagy from a one- or even two-day fast is almost negligible. What's the actual situation?
Very good questions. IDK if anyone has answers.
"it seemed to imply that ingesting a single calorie would completely reset the "momentum" of autophagy to zero" -- I find this quite implausible. A SINGLE calorie? No. Fifty calories maybe.
There's nothing magical about an ingested calorie versus a calorie from something endogenous. The body is constantly turning over materials (proteins, lipids, etc.), recycling them in part, converting to glucose or ketones and burning them for energy, and so on, and that holds true during a fast no less than at other times (and perhaps *more* than at other times). IOW, there are ALWAYS calories floating around.
Is an exogenous molecule somehow labeled "EXOGENOUS MOLECULE! TREAT THIS DIFFERENTLY!", versus an unlabeled endogenous molecule? No, of course not.
I get than any significant quantity of, say, exogenous carbohydrate could interrupt autophagy, at least for a time. Perhaps 10 grams would do it, although not for long. How long does it take to burn 40 calories worth of carb when you are fasting? An hour? How long could autophagy possibly be inhibited? Two hours, maybe?
IDK, I am just thinking aloud, and reasoning as best I can.
@@alan2102X yes exactly, that's how I saw things too.
I've tried to find answers on this for a long time... nobody seems to have the answer. But I like Alan's response as it's logical.
this is the real question, and the one i attempt to answer specifically with the mother of all fasts: dry
This is the golden question no one seems to have a definitive answer for. For now I will continue consuming the roughly 15-30 calories of creamer in my iced coffee every morning since I don't FEEL like it interrupts my fasts to a significant degree.
Thank you Thomas and infinite blessings!
Appreciate the information great help!!
Very good information!
I started water fasting years ago as fasting always gave me emotional and mental strength and helped to ground me. I eventually got out of fasting and now 10-15 years later I am water fasting again. This time I’m learning what is going on within the body as I fast. I’m learning that many people water fast but include tea and coffee, cream etc while fasting. I thought then you’re not in a true absolute fast (I wasn’t referring to autophagy as for me personally fasting was for “greater” purposes. Well now I’m learning about this amazing word and my body how it all works so Im so on board with fasting for several reasons including autophagy ☺️
My question is are you recommending the Organifi red juice during the fasting state or at the beginning of breaking the fast?
Sorry if you already explained this in the video explains this . I’ve listened to it 3 times. Trying to learn.
Much appreciation 👍🏼🌻
So many negative comments. All this free information... that you can skip through... rewind... people are wack .
Thanks bro you keep me going
I'm type 1 diabetic and need insulin around the clock because glucose is always being released from glycogen stores long after glucogenis has ceased and liver is expelled stores during fasting.
Since there's always glucose which are calories in bloodstream why would one calorie make a difference 🤔
Nice explanation of AMPK & MTOR...
Certain zero calorie ingredients and substances can stop or lessen autophagy for some people, such as stevia and monk fruit extract.
Great video. Your video's are super informative. I have been doing this all wrong. You have a really good way of breaking down some really wonky topics! thank you
So with this information I’m still unsure if lemon and ginger infused tea would cancel out the autophagy?
Does a shot of espresso(no sugar , no cream) stops autophagy?
No, it doesn’t.
Excellent lesson!
Skip to 3:54
discovered your channel recently, super helpful content and info, thank you!
Does black coffee has calories
Okay so Coffee with butter and/or collagen powder is a no go?
What about lemon juice?
Yep. Knows his stuff.
What about a bit of lemon juice in water?
SO NO CHEWABLE VITAMINS ON A FAST? i HAD ABOUT 10 VITAMIN C TABS YESTERDAY AND AM DOWN FOUR POUNDS THIS MORNING. 38 HOURS IN,,,,,,,,GREAT WORK THOMAS!
Great video! Doing carnivore and intermittent fasting.
Buying frozen berries is often cheaper, and the quality is good.
Loved the gremlin/troll picture, haha, it really helped to get a good understanding of what's happening in the body. Thanks!
Thank you for breaking this down for me.
During a prolonged fast, 20+ to 72 hours, are you now against having the lemon juice ACV stevia drink you have advocated?
I have notice that not all his advice is consistent
The only downside to fasting in my opinion is increased sensitivity to simple sugar
When fasting, one’s body is saving the glucose for the brain. The sugar sensitivity reduces after a couple days on carbs after a fast.
What do u mean increased sensitivity?
Your top elites have given you such good scripts... It's making me laugh so hard... 🤣🤣🤣
What about MCT oil? Does that kill autophagy?
Another awesome video. 👊
Thank you so much for sharing your God-given wisdom and brilliance with us!!!
Thanks man! 😁
This was an incredibly helpful video
What about consuming negative calorie foods? IE lettuce, popcorn
Now that was a good video!!!!!!!
I may be mistaken, but autophagy is really more about repairing the machinery than fueling it.
EVOO HAS HEAPS OF CALORIES but does it not enhance autophagy ? ?
How about lemon juice? Does it accelerate or block autophagy? What about strong ginger broth (1kg of ginger cooked down to 5 cups as a healing drink)?
Does it taste syrupy (even a little)?
Hope this helps!!
Those technically have calories so yes...
Thumbs up and subscribed!
What about MCT oil in coffee?
36 hours into my last fast I felt so much energy I went outside n ran 2 miles, I’ll keep it to 1 mile next time since I felt muscle fatigue as if I ran 5 miles but thats was a shocker that I went from weak n starving to death, to feeling energetic
There seems to be a controversy regarding autophagy as it takes 4 days on average to deplete liver of fuel. Why would autophagy begin before this depletion occurs.
Can something like brushing your teeth with toothpaste break your fast?
The calories thing is overblown and made confusing by influencers so they can get you to click on every video they create and keep you confused. A few calories for instance from something like a magnesium supplement or pomegranate extract in a pill supplement won’t stop autophagy just like coffee, which has 5-10 calories per serving won’t. Food will, like actual food and gum with sugars in it, otherwise no. Enough hand wringing
Lime water is cool tho too?
What do you think of Metformin for anti-aging? Would love your thoughts.
Great explanation! I didn't want to hear that..I liked it better when I believed creamer was ok 😂
Can increasing autophagy through intermittent fasting increase caffeine metabolism?
Thank you great information
I’m guessing that lime water ends it as well?
Ok one calorie.... But then how Long does it take for atophgy to kick in again
Did you ever find an answer? I ate a small piece of bread to be polite to an old lady, maybe 30 calories. Would love to know how long before autophagy kicks back in. By the way, I was 50 hours in to a fast.
@@nicsilva123 like half a day...
Already almost halfway into my 24 hour fast. Going to go to the gym fasted at around the 20th hour.
Thanks as always, Tom!
What about MCT oil?
What about lemon juice in water?
😂love the way you explain Mtor .
Would a garlic supplement break autophagy?
I've read that coffee will actually elevate glucose levels in some people. I'm just playing it safe and drinking only water with electrolytes during my 3-day fast.
What about lemon water?
Love the analogies! Makes it easy to understand the process going on during a fast & laugh at myself as i remember the "troll" guarding the bridges if I have some weakness & feel like breaking my fast! No way buddy troll, no calories for you! Thanks again for your sharing all your knowledge Thomas :)
Hello. I have been having a problem of indigestion, constipation and obesity.
I started fasting in 2021 and everything went away. My fasting ranges from 18:6 fasting to I meal a day (OMAD).
The problem is that I am now having problems of indigestion and constipation again and weight loss has stagnated
Thank You!
What about the fasting mimicking diet?
Idk y but when I saw the mtor picture I just lost it💀💀
When is the best time to take an ampk supplement, and why. Thanks
How does lemon juice affect a fast?
And when you say "creamer" are you talking "heavy whipping cream"? Or that sugary stuff that office coffee centers keep on hand?
He talks about lemon and lime juice here!
th-cam.com/users/clipUgkxQEQ3xvPVN2qdaQXNd1_kwLK46oqKhfYR
What if u use coconut cream
Good video.
Thanks Tom well guess no more creamer mushroom coffee i will drink this during a meal instead, i still drink green tea and also take ACV during the fast and lots of water with ice
Great vid!!!!
What about soft gel fish oil capsules?
Can I have olive oil with coffee and expect to have autophagy benefits? if so then how much of it should I consume in 1 cup of coffee?
Would lemon water stops autophagy ?
I was wondering the same thing. More so will lemon concentrate juice stop autophagy?
Can you do a video on maintaining Autophagy with Intermittent fasting, After a 3 day fast. I need Intermittent diet ideas for a $250 budget.
What about stevia
so does black coffee break a fast my black coffee says it has 6 calories so what now?
So black coffee is now bad during fasting. Back to just straight up water