I'm a medical doctor and this is hands down the best medical channel in youtube. Just straight science with the best available data and an objective non-biased interpetation. Keep up the good work Dr.Carvalho!
But why are there other doctors and nurses right now talking about a sudden recent increase in heart related sudden deaths? And he didn't mention this at all in this video. It's like trying to downplay heart disease right in the middle of possibly the largest increase of heart disease cases we have seen.
Agree. One of the best. I also really enjoy Vinnay Prasaad. Maybe not always as accessible. I'd love to see a collaboration or even a discussion where they disagree.
My grandfather lived on a farm and Never even saw any "modern" or processed food in his life. Yet he Died of atherosclerosis heart attack at the age of only 55
Genes have a lot to do with it. Hypercholesterolemia runs on my mother's side and her dad died of a heart attack at age 35 in the 50's so not much processed foods for him. This condition essentially results in high cholesterol no matter what you eat as most cholesterol is made in the body.
Hmm i truly wonder what he ate exactly, i eat saturated fat and meat, but i also eat around 3-4 pounds of vegetables a day which gives me 75 grams of fiber, we need more context, i know people who live on a farm, but eating whole grain bread with cheese is also not eating processed, but context matters
My great grandfather died in the 1940’s from atherosclerosis. He was a farmer and had access to lots of animal fats. I still have his wife’s cookbook, so I have a pretty good idea of what he was eating.
He's not telling people that they can eat what they want a live forever, so people don't watch him. They want to hear, "You can eat pork ribs everyday with fries and your cholesterol and high blood pressure won't kill you it's the pesticides in the side salads that are harmful. "
I’ve been plant based for 10 years. 38 year old guy and I’ve never felt better. I love this channel because I feel like you don’t try to sway somebody like all the other gurus. you simply put out the facts and the data and let us make up our own minds. Keep doing what you’re doing brother. Thank you.
From what I can find it from 1900 to 1960 it progressively got worse. 1900 heart disease was rare and there were many other things that were leading causes of death. By about 1924 heart disease had become the leading cause of death. Probably wasn't worse than now until about WW2
My great grandfather died in the 40s. My grandfather died in 1970. My father died 12 years ago. All were taken by a sudden massive cardio event. My great grandfather was 62. My grandfather was 65. My father was 68. My father was the only one to know "modern diet". He was the only one to be an alcoholic and have t2 diabetes & kidney disease yet he lived the longest. My grandfather's were very lean. Strong. Farmers.
Their issues could be genetic. You might want to have imaging done on your own heart. My son's paternal grandfather and all his siblings died with heart disease. They were missing a vessel leading away from the heart, which caused problems.
@@angusmurray3767 It's a losing game, Angus. Good punctuation, spelling, grammar, and syntax aren't a given. Those are skills that some don't have, or even care about. Yes, it's maddening.
That dude went from being a huge carnivore advocate to eating fruit and honey and then changing his story, whilst continuing to make money off of being a health influencer, very annoying
My grandfather father lived more than a 100 years without any illness! His younger brother still living until today. But his son died in his early 70s. Main change was: more refined carbs, less activity, more saturated fat, more eating in general.
I’ve wondered about this same thing. My maternal grandparents - eating lard and bacon and a typical, heavy, Midwestern farm diet for their entire lives - lived to 90 and 99 respectively. I’ve thought the switch from home raised, essentially organic, less activity (my grandpa farmed with horses for most of his life) and most of his farming career was before the explosion of ag chemicals following WWII, as well as very little processed food until they retired must play at least some part. My aunts and uncles ate a lot of processed food, had a much lower level of physical activity, and lived into their 70’s and 80’s.
Thank you for everything you do gil. You're the voice of reason, whilst there are thousands of people talking crap and trying to sell people stuff. I appreciate that you could do the same with your audience, but actually have a moral compass
My uncle had heart attack after heart attack, never ate any processed food (we don’t have them where I’m from), although he did manage to survive till 86, but he had many close calls along the way.
I’ve made several videos in the last few months saying heart disease, ldl, diabetes has an infection component. There are several organisms known to cause heart disease including Nanobacterium Sanguinum. In 2016 I had a “possible MI” on an EKG caused by toxic black mold. The infections are chronic and often subclinical such as a cavitation or undetected parasite in the gut.
Great video Dr. Gil! There’s a Vox article about protein consumption that has been going viral. Are you planning to make a video on it? Keep up the good work!
They weren't completely ignorant about medecine you know? There was a study in Boston if memory serves in very early 19th century (like 1803-1804) and they did tons of autopsies so they would have a better idea. Rythmic heart diseases accounted for about 3% of deaths according to them, and coronary heart diseases (=clogged arteries) were far behind this. Today people mean coronary disease when they say heart disease, it is a complete 180 from back then in the types and frequency of heart diseases. EDIT: 3%, not #% :p
Wow! You just blew holes right through a lot of stories I've heard on the internet, and that I have been a little too quick to accept as fact! This was a really fascinating and illuminating video to listen to. This is a multifaceted question, and each facet of it is a potential correlation that can be taken as a causation, or painted as a justification for any of a number of fad diets. Thanks so much for helping us to sort through the noise and figure out what is real science!!
I read a very interesting article that we, humans, genetically speaking, start developping atherosclerosis the moment we are born. The trick is knowing how to modulate it (slow it down) so we can enjoy a long life. Lp(a) is another genetic factor that was worth mentioning in this video and it existed since the dawn of history. Another interesting thing you mentioned concerning whether sat fats or grains are the culprit (we can't know) so there must be a common factor that discharges both which is Lp(a). Also developping type 2 diabetes is a strong contributor even if some people do not agree with this.
My grandmother never had highly processed food and died at 60 of stroke after eating a pig's head. My grandfather died of heart attack at 50. All my uncles (from my father's side) died of heart attack whether it was caused by chagas disease or simply because of bad diet! People love to romantize the "old times" as if we're more healthy back then when in reality we're much better off now! Today we're more aware of things and we have medicine at our disposal!
Indeed, though I think our high fat intake too in the US boosts our heart disease numbers, rather than just pure carbs. Tied into this, I was just reading this 2016 study from Japan -- "Dietary carbohydrate intake, presence of obesity and the incident risk of type 2 diabetes in Japanese men" -- where high carb intake is associated with T2 diabetes but only also in the presence of obesity, at www.ncbi.nlm.nih.gov/pmc/articles/PMC4847888/ -- It is a very interesting study with its comparisons to the types of carbs eaten both in Asian and Western populations too.
For sure too many processed carbs, I agree, but also phenominal amounts of meat, which has no fibre, and saturated fat and cholesterol. Athersclerosis doesn't exist in cats, dogs, tigers, lions, etc...because they are able to efficiently deal with sat fat and cholesterol - humans can't- we are very heavily prone to athersclerosis.
You don't have to "believe" that. Even if you control for calories, most types of saturared fats raise ApoB and LDL which are causal risk factors of CVD, and so are excess refined sugar. Question is whether it is these isolated foods that are "bad" no matter what or whether other dietary patterns can make up for it (lifestyle and weight does too to an extent)
So people who do Yoga everyday doesn't get heart disease not matter what their diet? If stress was a significant risk factor for cancer, then no children under 10 would had died from it. Stress is not a significant risk factor for heart disease either. During WW2 the nations Hitler occupied had their livestock stolen and were under food rationing. The stress of this event should cause mortality incidences from chronic diseases to go up, however, during these years they were their lowest.
This may be back to the drawing board for me. I decided to look into this. I thought: "Well, if it is natural, then other long-lived mammals would get it too," so I searched for heart disease in Elephants. And low and behold, elephants get it too. So whatever the explanation, it likely has to also apply to wild elephants, as what I found was from 500 killed wild elephants in East Africa. Elephants are vegan, get plenty of exercise, they are not cooking their food so low Advanced Glycation End-products, no trans fat, no acrylamide. They are not breathing smog, not drinking alcohol, not getting too much salt or drinking chlorinated water. If it is pathogen caused, then it must be a pathogen we can both get or there must be another version they also can get. Mostly low stress, and they are social and are always with their friends. There are times they probably even have near fasts. No blue light at night. Plenty of vitamin D. The doctors that say if particular health advises is followed, almost no one would die of this? How can that be, if wild elephants are dying of this? Lead is possible. I looked at the maps and there is lead. They eat a lot of grasses. Those grasses could have absorbed lead from the earth. Low level lead was found to be killing 412,000 Americans every year. The way I see it, it is either lead and/or pathogens. That is not to say none of those other things matter, just that it is unlikely controlling them is sufficient.
That brings us back straight to the Mediterranean diet. I think moderation of everything assist in better health, a good balance and lower or no processed foods and sugars with exercise. This is how I live my life now. The extremes seem not to be rightly suited according to your data.I have gotten some real headaches due to the fact that I have been binging on your videos in the last 2 weeks. I mean , I just can't stop. I love you evidence based information and when you debunk most of the things people selling to viewers here. please keep your videos coming. Extremely thought provoking and informative.
This is just amazing Dr Gil, THANK YOU for what you're doing. Your information has just the right amounts of technical rigor as well as references. You have no idea the hours of debate you've saved me and no doubt a few thousand of others here. You have also helped me be more respectful to those with differing opinions and less knowledge and the genuinely perplexed - just by the way your explanations and debunkings and responses have gotten so balanced over time - respectful yet firm about the science and data. Your channel is a delightful an informative masterclass. Shukran daktari as we say in Swahili. Thank you Doc
Aside from heart disease, there's a lot of ideas out there now about how the prevalence of many conditions (allergies, autoimmune diseases, cancer to name a few) has increased drastically in just the past few decades or past century. The blame gets put on everything from seed oils to chemical farming to vaccines, to sedentary lifestyles. I'd be interested to know how much of the rise in health conditions is true across all developed nations and how much of it is due to better screening etc.
When people migrate from one country to another (and so usually one food and exercise culture to another) their health status generally reflects the health status of the lifestyle they adopt (their initial culture or the one they migrate too). When countries adopt a standard western food and exercise culture their health status reflects that of the other countries with this culture.
Great video. Have there been any studies into whether other primates suffer from atherosclerosis / heart disease? It would be interesting to know whether it's only the human branch that is susceptible to this.
@DavidColeman0896 Yup. A wide range of animals can get heart disease. It's best studied in domestic pets and livestock though. Modern meat chickens have it particularly rough - the selection/breeding for super rapid growth also made them extremely susceptible to heart disease (a typical chicken reaches adult size at 6 - 8 months and lives 5 - 7 years. A broiler reaches full size by 2 months and is unlikely to live a year, almost always dying of a heart attack). Heart disease is a fairly common killer of pets as well.
A quick search on Google scholar will show a bunch if info showing that yes, other primates can suffer heart disease and you can induce it by putting them on a high sat fat diet or jacking up their serum cholesterol in other ways
Thank you for clarifying this! I’m so tired of the paleo community claiming that the Alaskan eskimos ate all this whale fat and never had any heart disease. Maybe they did somehow evolve slightly so it’s like what you said with this being a genetic trait and the ones that developed more heart disease probably didn’t live as long and the genes didn’t get passed along as much.
Reproductive success doesn't really correlate much with diet type and health, since reproduction mostly happens in younger, healthier years. Health risks start to become expressed at older ages. Especially heart disease. Edit: This does not mean ethnic dietary differences don't have an effect on genetic predispositions for food tolerance and chronic illness, these changes certainly do exist. I was specifically referring to health outcomes and longevity.
@@jegbryrmegikke1 Yes, there are differences. For example, look up: "CPT1A Missense Mutation Associated With Fatty Acid Metabolism and Reduced Height in Greenlanders".
Something mentioned in this video that raised a question for me was the rapid rise of heart disease per capita in the 1st half of the 20th century followed by a sudden drop up until today. Improved treatments and medications were mentioned as possibly providing more successful intervention. We may very well be seeing an increase in heart disease while at the same time it's being masked by improved treatment. Lifespans in the US were generally improving until recently while poor heath spans (living longer but in poor health) appear to be on the rise. We can stop more things from being fatal early on, such as severe trauma and acute disease symptoms with more advanced interventions, but that doesn't mean general health is better. Look at the increasing levels of obesity. In my mind there is still an urgent need for people to improve their lifestyle habits, with eating habits a key one. I opt for preventing versus fixing.
I agree wholeheartedly. It is interesting how success in our medical system is aversion of death and the quantity of years lived but really does not put any emphasis on the quality of life or one's ability to live with dignity. I think data such as these would lead one to very different conclusions and recommendations than the one's generally expressed. America has sick care, not health care.
@@sweetbizilwhile I think there is ample room for improvement in medicine, I think you are making an over generalization by saying the medical profession is focused sick care versus health care. Doctors can tell people all they want about changing their diet, patients have to follow through. I don’t know of any healthcare plan that does not offer dieticians/nutritionists as a service. Once again, though, people have to follow through and most don’t. Then you add on top of that the difficulties of making new habits and you get a different story than merely it being a failure of the medical establishment.
Agreed. 'Sick care' is another term used often and accurate. I'm in my late 60's, in perfect health and taking no medications. I've eaten a balanced whole foods diet my entire life, avoid ultra processed foods and restaurants, exercise daily, and have been long distance biker and runner for several years. Lifestyle matters. It saddens me to see so many people my age whose lives are compromised by being in miserable shape and taking multiple medications while still having only limited mobility and energy.
Excellent summary and conclusion of the data available regarding historical prevalence of arthrosclerosis What modern CRRAHP ( calorie rich, refined and highly processed) foods and beverages, and more specifically massive increases in calorie availability combined with decreases in physical movement required for life, has increased is the risk of in the modern day is type 2 diabetes and it’s kissing cousin, higher average body fat to muscle ratio.
So interesting!!! Thank you so so so much for this channel. I can't thank you enough. As a dietitian I'm always looking forward to your next video ! Based on facts an science. Thank you
Because most ancient mummies were from higher status groups in their communities, maybe they were also eating richer foods and were less active? Could that have had an impact on the findings? Love your channel
@hidden909 The Ice Man was not of elite status. He was a lonely, isolated, hunted and murdered man on the run. Trapped in ice for 5000 years. The perfect biological snapshot of an ordinary man of that time and place.
I had assumed modern food would make CAD worse, and that CAD was always around, but i am blown away as to the amount found. Really interesting stuff-----Thanks
it would be interesting to see when blood thinners like aspirin were introduced and what effect it had on preventing heart attacks . stents could be another one to look at .My dad 74, just had 2 stents this morning and hes already feeling like hes 20 years younger by the afternoon!
I'd be curious to know if other mammals get atherosclerosis. Considering how hard it was to make it past childhood in the past, survival of the fittest may have simply depended on not dying of an infection or trauma to the body. Diseases that take decades to kill you are kind of a luxury!
Thanks for encouraging critical thinking and the habit of cross checking. Time to look at the all references you’ve shared . It’s going to be an interesting read.
Thanks Gil, another great video! I’ve certainly heard this myth repeated in documentaries as well as on social media. There is a similar claim that I’ve seen thrown around also: that obesity didn’t exist (roughly) half a century ago, and therefore diseases associated with obesity were largely non-existent. I’d love to see your take on this!
You don't have to obese in order to get cardiovascular disease or any chronic illness. Plus folks smoked more in the past, you can see that cardiovascular disease incidence decrease in the previous century when smoking rates went down. Franklin D. Roosevelt(chain-smoker), Woodrow Wilson both died from cardiovascular disease. They weren't obese
Never knowing when and if you would be eating next was probably very stressful and would push cortisol through the roof. Nowadays we worry differently but the effect on the body is probably similar. So genetic predisposition and environmental factors are always at play.
I am still confused as to why some people get calcified arterial plaque that sticks to the artery walls and some don’t? And the cause of the same? Keep hearing the word inflammation but still in spite of this cause if true some people evidently do not get calcified arterial plaque?
Hi Dr Gil, I've watched a lot of your videos recently and you've caused me to rethink a lot of basic dietary beliefs I've carried around for several decades, like that saturated fat is benign, PUFAs aren't, and LDL cholesterol is nothing to worry about. You're going after another one in this video (ie, CVD began a century or two ago). Thank you so much. However, one thing that would concern me with the info presented here is the cause-of-death statistics. I would worry that some countries seem to have a default cause of death that is often assigned in the absence of anything obvious, and often that seems to be 'heart attack' (similar controversy over the last few years over whether people are dying of Covid, vs dying with Covid and being labeled Covid deaths). This can vary over time and between countries, and I'm not terribly certain that CVD fatality diagnoses in 1910, 1950, and 1990, and in the US vs Britain vs Australia, are really the same thing.
Well done presentation. I would like to add that the Top 10 causes of death in 1900 have heart disease listed in #4 spot. Contrast to modern day where it sits at #1. Hence, the way we currently live as compared to life in the 1800s has to be taken into account.
That's true but if you add in deaths from stroke (intercranial lesions of vascular origin), then cardiovascular disease was the leading cause of death in 1900. And not many people die from diarrhea or TB these days either. Not in the US anyway.
@@tomgoff7887 Cerebrovascular disease is currently divided from heart disease and listed at #4 spot, and still heart disease is the leading killer of Americans.
The first time a person was diagnosed with alzheimer was on 1906 She spent her last days in a mental asylum. However the same thing that prevents cardiovascular disease, also prevents dementia.
Could you please make a video on coffee? A lot of controversy on this topic. So far I try no to exceed on my coffee consumption (I limit to 500 mL of pour over coffee) and also try to drink it before 10am to not affect my sleep.
Nice presentation. Question: What’s your definition of heart disease - coronary artery plaque? Cardiomyopathy? Valvular disease? Arrhythmia without plaque? Your presentation seems to focus only on coronary artery disease. But even this is a little vague. Are we talking about a little bit of plaque no matter how inconsequential? A lot? Moderate? Plaque location? LAD more significant than circumflex? More questions raised than answered, unfortunately. Also, I don’t know how much credence I would place on diagnostic criteria from data gleaned in 1880 - their diagnostic tools were fairly limited. As usual, all this stuff has to be taken with a grain of salt. Also, CT/MRI data from mummies is questionable since the mummified state will alter the plaque burden seen on the scan.
This made me wonder how prevalent AS and CVD is in the animal kingdom at large. Is there data for hominids, or even ruminants and predators, living in the wild right now? Would love to see how that correlates to the current and historic human data.
My 2c: 1. In ancient times, only the most wealthy people had their body preserved and mummified. Most probably, those wealthy folks were not physically active. 2. Unangans nutrition was primarily based on fatty fish and meat. The calcified arteries of Otzi the ice-man are very intriguing!
A fascinating explanation of the weaknesses of population studies. What interests me is the nearly unique susceptibility of humans to heart disease. I think thee are a number of proposed explanations, any of which might be true. But one observation I think holds: evolutionary pressure to overcome this susceptibility is minimal because most humans reproduce before reaching the age where heart disease becomes a major risk. That doesn't mean we can't do anything about it. But we need to be aware of our weaknesses.
I'm a medical doctor and this is hands down the best medical channel in youtube. Just straight science with the best available data and an objective non-biased interpetation. Keep up the good work Dr.Carvalho!
Agree. Gil's talent for distilling down complex research topics into easily digested nuggets is unparalleled.
Well said! 👏
But why are there other doctors and nurses right now talking about a sudden recent increase in heart related sudden deaths? And he didn't mention this at all in this video. It's like trying to downplay heart disease right in the middle of possibly the largest increase of heart disease cases we have seen.
@@Masterr59 You're confusing different types of heart problems. There are many.
Agree. One of the best. I also really enjoy Vinnay Prasaad. Maybe not always as accessible. I'd love to see a collaboration or even a discussion where they disagree.
Is anyone else just blown away by the depth of coverage and nuance in Gil’s vids? A pleasure to listen to, thank you.
My grandfather lived on a farm and Never even saw any "modern" or processed food in his life. Yet he Died of atherosclerosis heart attack at the age of only 55
Yeah, probably mostly simply caused from ingesting too much animal products, salt and alchohol, it it well known.
Genes have a lot to do with it. Hypercholesterolemia runs on my mother's side and her dad died of a heart attack at age 35 in the 50's so not much processed foods for him. This condition essentially results in high cholesterol no matter what you eat as most cholesterol is made in the body.
My grandfather regularly ate lard and smoked, that was common for his generation. he died in his 60's.
Hmm i truly wonder what he ate exactly, i eat saturated fat and meat, but i also eat around 3-4 pounds of vegetables a day which gives me 75 grams of fiber, we need more context, i know people who live on a farm, but eating whole grain bread with cheese is also not eating processed, but context matters
My great grandfather died in the 1940’s from atherosclerosis. He was a farmer and had access to lots of animal fats. I still have his wife’s cookbook, so I have a pretty good idea of what he was eating.
This channel is so underrated.
He's not telling people that they can eat what they want a live forever, so people don't watch him. They want to hear, "You can eat pork ribs everyday with fries and your cholesterol and high blood pressure won't kill you it's the pesticides in the side salads that are harmful. "
I’ve been plant based for 10 years. 38 year old guy and I’ve never felt better. I love this channel because I feel like you don’t try to sway somebody like all the other gurus. you simply put out the facts and the data and let us make up our own minds. Keep doing what you’re doing brother. Thank you.
Some people can but the vast majority won't due to sensitivities to phytochemicals in large quantities
@@ryanwellington7493 source you base that on?
@@ryanwellington7493 Based on absolutely nothing.
I went plant based 2.5 months ago. So far systolic BP is down 20 points, LDL dropped from 135 to 90, and I've lost 23 lbs with no effort.
@@ryanwellington7493 "won't" is the key word. Sensitivities can be overcome and worked around.
I had no idea that the heart disease situation has actually improved over the last 100 years
Neither had I. It's fascinating!
Statins are a hellava drug.
That could just be due to newer medical interventions though
Lower rates of smoking probably helped. Less use of lard/butter, shortening in cooking post WW2 probably played a role too.
From what I can find it from 1900 to 1960 it progressively got worse. 1900 heart disease was rare and there were many other things that were leading causes of death. By about 1924 heart disease had become the leading cause of death. Probably wasn't worse than now until about WW2
My great grandfather died in the 40s. My grandfather died in 1970. My father died 12 years ago. All were taken by a sudden massive cardio event. My great grandfather was 62. My grandfather was 65. My father was 68. My father was the only one to know "modern diet". He was the only one to be an alcoholic and have t2 diabetes & kidney disease yet he lived the longest. My grandfather's were very lean. Strong. Farmers.
What’s your point
Their issues could be genetic. You might want to have imaging done on your own heart. My son's paternal grandfather and all his siblings died with heart disease. They were missing a vessel leading away from the heart, which caused problems.
I'd be willing to bet they smoked and drank too.
The plural of grandfather is grandfathers. Why do you write grandfather's?? Why is it so difficult for people to tell a plural from a possessive?
@@angusmurray3767 It's a losing game, Angus. Good punctuation, spelling, grammar, and syntax aren't a given. Those are skills that some don't have, or even care about. Yes, it's maddening.
Kudos for breaking a huge myth in the field. It's a hard job, Dr. Gil, but someone has to do it. And you do it so well.
You won't see Salidino go over this. It would kill his diet theory.
Who is that agian?
Heart disease is correlated with smoking. Period.
@@rubygreta1among other risk factors that need to be squeezed in ahead of that period!
That guy is first and foremost a business man. I gave up following him once I realised that.
That dude went from being a huge carnivore advocate to eating fruit and honey and then changing his story, whilst continuing to make money off of being a health influencer, very annoying
My grandfather father lived more than a 100 years without any illness! His younger brother still living until today. But his son died in his early 70s. Main change was: more refined carbs, less activity, more saturated fat, more eating in general.
I’ve wondered about this same thing. My maternal grandparents - eating lard and bacon and a typical, heavy, Midwestern farm diet for their entire lives - lived to 90 and 99 respectively.
I’ve thought the switch from home raised, essentially organic, less activity (my grandpa farmed with horses for most of his life) and most of his farming career was before the explosion of ag chemicals following WWII, as well as very little processed food until they retired must play at least some part. My aunts and uncles ate a lot of processed food, had a much lower level of physical activity, and lived into their 70’s and 80’s.
Actually people eat more and more polyunsaturated fats, and less saturated fats since the 70s. You're right about the rest.
Thank you for the common sense, balanced analysis Gil. I appreciate all you do to keep us informed and educated.
Dr. Carvalho the myth buster ! The only medical channel I fully trust and rely on. Bless you Dr. Carvalho.
Thank you for everything you do gil. You're the voice of reason, whilst there are thousands of people talking crap and trying to sell people stuff. I appreciate that you could do the same with your audience, but actually have a moral compass
I learned a lot here. So cool about the tattoos, too. Thanks, Gil.
It will be nice to hear your take on this. 😅
I love seeing physionic in this comments section.
I’d love to see this same analysis on modern foods and diabetes. Thanks for quality education here on your channel.
My uncle had heart attack after heart attack, never ate any processed food (we don’t have them where I’m from), although he did manage to survive till 86, but he had many close calls along the way.
Well then, there's hope for me yet!
Great video Gill, I like how you Incorporated the part about mummies.
I’ve made several videos in the last few months saying heart disease, ldl, diabetes has an infection component. There are several organisms known to cause heart disease including Nanobacterium Sanguinum. In 2016 I had a “possible MI” on an EKG caused by toxic black mold.
The infections are chronic and often subclinical such as a cavitation or undetected parasite in the gut.
Great video Dr. Gil! There’s a Vox article about protein consumption that has been going viral. Are you planning to make a video on it? Keep up the good work!
Another thing to consider is that there were probably a lot more deaths from heart disease that weren't recognized as being such in the early 1900's.
They weren't completely ignorant about medecine you know? There was a study in Boston if memory serves in very early 19th century (like 1803-1804) and they did tons of autopsies so they would have a better idea. Rythmic heart diseases accounted for about 3% of deaths according to them, and coronary heart diseases (=clogged arteries) were far behind this. Today people mean coronary disease when they say heart disease, it is a complete 180 from back then in the types and frequency of heart diseases.
EDIT: 3%, not #% :p
Wow! You just blew holes right through a lot of stories I've heard on the internet, and that I have been a little too quick to accept as fact! This was a really fascinating and illuminating video to listen to. This is a multifaceted question, and each facet of it is a potential correlation that can be taken as a causation, or painted as a justification for any of a number of fad diets. Thanks so much for helping us to sort through the noise and figure out what is real science!!
I read a very interesting article that we, humans, genetically speaking, start developping atherosclerosis the moment we are born. The trick is knowing how to modulate it (slow it down) so we can enjoy a long life. Lp(a) is another genetic factor that was worth mentioning in this video and it existed since the dawn of history. Another interesting thing you mentioned concerning whether sat fats or grains are the culprit (we can't know) so there must be a common factor that discharges both which is Lp(a). Also developping type 2 diabetes is a strong contributor even if some people do not agree with this.
Phenomenal. Please know that your content is very appreciated
Amen. This channel shows us how to think clearly and objectively.
I really loved this video, I hope it opens some people's eyes. Thank you!
My grandmother never had highly processed food and died at 60 of stroke after eating a pig's head. My grandfather died of heart attack at 50. All my uncles (from my father's side) died of heart attack whether it was caused by chagas disease or simply because of bad diet! People love to romantize the "old times" as if we're more healthy back then when in reality we're much better off now! Today we're more aware of things and we have medicine at our disposal!
Great video! Thanks!
Whatever caused heart disesae before processed carbohydrates, it doesn't change the fact that many americans eat too much processed carbs today.
You mean processed carbohydrates and fats.
Indeed, though I think our high fat intake too in the US boosts our heart disease numbers, rather than just pure carbs. Tied into this, I was just reading this 2016 study from Japan -- "Dietary carbohydrate intake, presence of obesity and the incident risk of type 2 diabetes in Japanese men" -- where high carb intake is associated with T2 diabetes but only also in the presence of obesity, at www.ncbi.nlm.nih.gov/pmc/articles/PMC4847888/ -- It is a very interesting study with its comparisons to the types of carbs eaten both in Asian and Western populations too.
Too many calories...regardless of source.
For sure too many processed carbs, I agree, but also phenominal amounts of meat, which has no fibre, and saturated fat and cholesterol. Athersclerosis doesn't exist in cats, dogs, tigers, lions, etc...because they are able to efficiently deal with sat fat and cholesterol - humans can't- we are very heavily prone to athersclerosis.
You don't have to "believe" that. Even if you control for calories, most types of saturared fats raise ApoB and LDL which are causal risk factors of CVD, and so are excess refined sugar. Question is whether it is these isolated foods that are "bad" no matter what or whether other dietary patterns can make up for it (lifestyle and weight does too to an extent)
Stress seems to be a big fat factor in heart disease, and you can overstress in any time in history. Even millions of years ago.
We've only been on the earth 6.000 yrs '
So people who do Yoga everyday doesn't get heart disease not matter what their diet?
If stress was a significant risk factor for cancer, then no children under 10 would had died from it.
Stress is not a significant risk factor for heart disease either. During WW2 the nations Hitler occupied had their livestock stolen and were under food rationing. The stress of this event should cause mortality incidences from chronic diseases to go up, however, during these years they were their lowest.
There are tons of eskimo/inuit unintentional mummies with hardened arteries.
The mummies have had most of the water literally sublimate, so maybe collagen had simply didintegrated because of that.
More like 3-4, unless you have more recent sources?
Fascinating stuff. Thanks for the video
This may be back to the drawing board for me. I decided to look into this. I thought: "Well, if it is natural, then other long-lived mammals would get it too," so I searched for heart disease in Elephants. And low and behold, elephants get it too. So whatever the explanation, it likely has to also apply to wild elephants, as what I found was from 500 killed wild elephants in East Africa.
Elephants are vegan, get plenty of exercise, they are not cooking their food so low Advanced Glycation End-products, no trans fat, no acrylamide. They are not breathing smog, not drinking alcohol, not getting too much salt or drinking chlorinated water. If it is pathogen caused, then it must be a pathogen we can both get or there must be another version they also can get. Mostly low stress, and they are social and are always with their friends. There are times they probably even have near fasts. No blue light at night. Plenty of vitamin D.
The doctors that say if particular health advises is followed, almost no one would die of this? How can that be, if wild elephants are dying of this?
Lead is possible. I looked at the maps and there is lead. They eat a lot of grasses. Those grasses could have absorbed lead from the earth. Low level lead was found to be killing 412,000 Americans every year. The way I see it, it is either lead and/or pathogens.
That is not to say none of those other things matter, just that it is unlikely controlling them is sufficient.
The incidence of heart disease is what I’m interested in. The number of new cases per year.
Direct correlation between decline in smoking and decline in heart disease.
That brings us back straight to the Mediterranean diet. I think moderation of everything assist in better health, a good balance and lower or no processed foods and sugars with exercise. This is how I live my life now. The extremes seem not to be rightly suited according to your data.I have gotten some real headaches due to the fact that I have been binging on your videos in the last 2 weeks. I mean , I just can't stop. I love you evidence based information and when you debunk most of the things people selling to viewers here. please keep your videos coming. Extremely thought provoking and informative.
Thanks again for your fascinating and thought-provoking content.
This is just amazing Dr Gil, THANK YOU for what you're doing. Your information has just the right amounts of technical rigor as well as references. You have no idea the hours of debate you've saved me and no doubt a few thousand of others here. You have also helped me be more respectful to those with differing opinions and less knowledge and the genuinely perplexed - just by the way your explanations and debunkings and responses have gotten so balanced over time - respectful yet firm about the science and data. Your channel is a delightful an informative masterclass. Shukran daktari as we say in Swahili. Thank you Doc
I’m enjoying your content since discovering your channel thru my feed, Gil.😊
Thanks for breaking this down! Rarely can we tell a complete picture from just 1 graph, as you demonstrated!
Howdy Gil. Love your videos - keep up the great work!
Aside from heart disease, there's a lot of ideas out there now about how the prevalence of many conditions (allergies, autoimmune diseases, cancer to name a few) has increased drastically in just the past few decades or past century. The blame gets put on everything from seed oils to chemical farming to vaccines, to sedentary lifestyles. I'd be interested to know how much of the rise in health conditions is true across all developed nations and how much of it is due to better screening etc.
Great video, thank you!
Fantastic Video as usual!
Thanks for the information.
When people migrate from one country to another (and so usually one food and exercise culture to another) their health status generally reflects the health status of the lifestyle they adopt (their initial culture or the one they migrate too). When countries adopt a standard western food and exercise culture their health status reflects that of the other countries with this culture.
Great video. Have there been any studies into whether other primates suffer from atherosclerosis / heart disease? It would be interesting to know whether it's only the human branch that is susceptible to this.
Yes. Wild and captive primates develop atherosclerosis just like humans.
@@DM-ql6ps Interesting. How about other non-primate animals
@DavidColeman0896 Yup. A wide range of animals can get heart disease. It's best studied in domestic pets and livestock though. Modern meat chickens have it particularly rough - the selection/breeding for super rapid growth also made them extremely susceptible to heart disease (a typical chicken reaches adult size at 6 - 8 months and lives 5 - 7 years. A broiler reaches full size by 2 months and is unlikely to live a year, almost always dying of a heart attack). Heart disease is a fairly common killer of pets as well.
@@DM-ql6psThanks for the info. What is the source?
A quick search on Google scholar will show a bunch if info showing that yes, other primates can suffer heart disease and you can induce it by putting them on a high sat fat diet or jacking up their serum cholesterol in other ways
Thank you for clarifying this! I’m so tired of the paleo community claiming that the Alaskan eskimos ate all this whale fat and never had any heart disease. Maybe they did somehow evolve slightly so it’s like what you said with this being a genetic trait and the ones that developed more heart disease probably didn’t live as long and the genes didn’t get passed along as much.
hard to only say it is food related? has to be alot about general health condition and how much we work out?
Yes, apparently these traditional arctic peoples don't go into ketosis, for example.
Reproductive success doesn't really correlate much with diet type and health, since reproduction mostly happens in younger, healthier years. Health risks start to become expressed at older ages. Especially heart disease.
Edit: This does not mean ethnic dietary differences don't have an effect on genetic predispositions for food tolerance and chronic illness, these changes certainly do exist. I was specifically referring to health outcomes and longevity.
does not sound true at all. Humans are not that different, i am from norway and these people are not that different.@@carinaekstrom1
@@jegbryrmegikke1 Yes, there are differences. For example, look up: "CPT1A Missense Mutation Associated With Fatty Acid Metabolism and Reduced Height in Greenlanders".
Something mentioned in this video that raised a question for me was the rapid rise of heart disease per capita in the 1st half of the 20th century followed by a sudden drop up until today. Improved treatments and medications were mentioned as possibly providing more successful intervention. We may very well be seeing an increase in heart disease while at the same time it's being masked by improved treatment. Lifespans in the US were generally improving until recently while poor heath spans (living longer but in poor health) appear to be on the rise. We can stop more things from being fatal early on, such as severe trauma and acute disease symptoms with more advanced interventions, but that doesn't mean general health is better. Look at the increasing levels of obesity. In my mind there is still an urgent need for people to improve their lifestyle habits, with eating habits a key one. I opt for preventing versus fixing.
I agree wholeheartedly. It is interesting how success in our medical system is aversion of death and the quantity of years lived but really does not put any emphasis on the quality of life or one's ability to live with dignity. I think data such as these would lead one to very different conclusions and recommendations than the one's generally expressed. America has sick care, not health care.
@@sweetbizilwhile I think there is ample room for improvement in medicine, I think you are making an over generalization by saying the medical profession is focused sick care versus health care. Doctors can tell people all they want about changing their diet, patients have to follow through. I don’t know of any healthcare plan that does not offer dieticians/nutritionists as a service. Once again, though, people have to follow through and most don’t. Then you add on top of that the difficulties of making new habits and you get a different story than merely it being a failure of the medical establishment.
Agreed. 'Sick care' is another term used often and accurate. I'm in my late 60's, in perfect health and taking no medications. I've eaten a balanced whole foods diet my entire life, avoid ultra processed foods and restaurants, exercise daily, and have been long distance biker and runner for several years. Lifestyle matters. It saddens me to see so many people my age whose lives are compromised by being in miserable shape and taking multiple medications while still having only limited mobility and energy.
The rate of heart disease probably correlates with rates of smoking.
That is correct!!@@brocklastname6682
Great video Gil!
We could use more critical thinking in every aspect of our lives, frankly, so this is good advice overall.
Good one Gil. I did try to het information on this topic myself years ago but it was difficult. Thank you 😊
Super Interesting! Thanks for sharing Dr Carvalho
Excellent summary and conclusion of the data available regarding historical prevalence of arthrosclerosis
What modern CRRAHP ( calorie rich, refined and highly processed) foods and beverages, and more specifically massive increases in calorie availability combined with decreases in physical movement required for life, has increased is the risk of in the modern day is type 2 diabetes and it’s kissing cousin, higher average body fat to muscle ratio.
Excellent content! Thanks for the rigorous, fact-based presentation. Bringing rationality to the confusing.
Thanks for clarification!
Fascinating report.
Super interesting video! Would be interesting to see the atherosclerosis levels in people that lived to 100.
Excellent data - thank you!
So interesting!!! Thank you so so so much for this channel.
I can't thank you enough. As a dietitian I'm always looking forward to your next video !
Based on facts an science. Thank you
Thank you for this! I new about the Egyptian mummies with CVD and always wondered about pre-agricultural people
This video makes me think of The China Study. We'rnt the Chinese low on heart disease before the introduction of Western food influences?
Very interesting. Another great video, thanks!
Hugely interesting. Do you have current info on MS? Nutrition, meds, studies, new findings? I’d love to hear what you know.
Because most ancient mummies were from higher status groups in their communities, maybe they were also eating richer foods and were less active? Could that have had an impact on the findings? Love your channel
@hidden909 The Ice Man was not of elite status. He was a lonely, isolated, hunted and murdered man on the run. Trapped in ice for 5000 years. The perfect biological snapshot of an ordinary man of that time and place.
I had assumed modern food would make CAD worse, and that CAD was always around, but i am blown away as to the amount found. Really interesting stuff-----Thanks
amazing video. what a concept!
Very interesting. Thank you 😊
Great, as always!
Fascinating stuff!
it would be interesting to see when blood thinners like aspirin were introduced and what effect it had on preventing heart attacks .
stents could be another one to look at .My dad 74, just had 2 stents this morning and hes already feeling like hes 20 years younger by the afternoon!
Please can you present on diet and osteoarthritis. Plus diet and muscle atrophy reversal. 🙏
I'd be curious to know if other mammals get atherosclerosis. Considering how hard it was to make it past childhood in the past, survival of the fittest may have simply depended on not dying of an infection or trauma to the body. Diseases that take decades to kill you are kind of a luxury!
Thank you
Great vid, thanks!
Great video! As always...
Thanks for encouraging critical thinking and the habit of cross checking. Time to look at the all references you’ve shared . It’s going to be an interesting read.
Another excellent analysis, 🙏
loved the top gun reference. thanks.
Thanks Gil, another great video! I’ve certainly heard this myth repeated in documentaries as well as on social media.
There is a similar claim that I’ve seen thrown around also: that obesity didn’t exist (roughly) half a century ago, and therefore diseases associated with obesity were largely non-existent. I’d love to see your take on this!
You don't have to obese in order to get cardiovascular disease or any chronic illness.
Plus folks smoked more in the past, you can see that cardiovascular disease incidence decrease in the previous century when smoking rates went down.
Franklin D. Roosevelt(chain-smoker), Woodrow Wilson both died from cardiovascular disease. They weren't obese
really enlightening video doc
This is really interesting.
Never knowing when and if you would be eating next was probably very stressful and would push cortisol through the roof. Nowadays we worry differently but the effect on the body is probably similar. So genetic predisposition and environmental factors are always at play.
Did the mummies with atherosclerotic plaques have apoe 4 homozygous?
I am still confused as to why some people get calcified arterial plaque that sticks to the artery walls and some don’t? And the cause of the same? Keep hearing the word inflammation but still in spite of this cause if true some people evidently do not get calcified arterial plaque?
Hi Dr Gil, I've watched a lot of your videos recently and you've caused me to rethink a lot of basic dietary beliefs I've carried around for several decades, like that saturated fat is benign, PUFAs aren't, and LDL cholesterol is nothing to worry about. You're going after another one in this video (ie, CVD began a century or two ago). Thank you so much.
However, one thing that would concern me with the info presented here is the cause-of-death statistics. I would worry that some countries seem to have a default cause of death that is often assigned in the absence of anything obvious, and often that seems to be 'heart attack' (similar controversy over the last few years over whether people are dying of Covid, vs dying with Covid and being labeled Covid deaths). This can vary over time and between countries, and I'm not terribly certain that CVD fatality diagnoses in 1910, 1950, and 1990, and in the US vs Britain vs Australia, are really the same thing.
Well done presentation. I would like to add that the Top 10 causes of death in 1900 have heart disease listed in #4 spot. Contrast to modern day where it sits at #1. Hence, the way we currently live as compared to life in the 1800s has to be taken into account.
And of course, it all has to be interpreted in the context of life span.
That's true but if you add in deaths from stroke (intercranial lesions of vascular origin), then cardiovascular disease was the leading cause of death in 1900. And not many people die from diarrhea or TB these days either. Not in the US anyway.
@@tomgoff7887 Cerebrovascular disease is currently divided from heart disease and listed at #4 spot, and still heart disease is the leading killer of Americans.
You need more Subscribers! Cheers
What is the percentage of wild animals that get atherosclerosis?
Scientific inquiry, observation, discovery, and analysis have a way of destroying long-held myths and preferred beliefs...
Would be very interesting for apart to on processed food and the scientifically proven effects on risks such as dementia
The first time a person was diagnosed with alzheimer was on 1906
She spent her last days in a mental asylum.
However the same thing that prevents cardiovascular disease, also prevents dementia.
Again a great vide based on evidence based science.
Can you do some videos on Peanut Butter and "sugar in fruits"?? Thanks
Could you please make a video on coffee? A lot of controversy on this topic. So far I try no to exceed on my coffee consumption (I limit to 500 mL of pour over coffee) and also try to drink it before 10am to not affect my sleep.
great video
Nice presentation. Question: What’s your definition of heart disease - coronary artery plaque? Cardiomyopathy? Valvular disease? Arrhythmia without plaque? Your presentation seems to focus only on coronary artery disease. But even this is a little vague. Are we talking about a little bit of plaque no matter how inconsequential? A lot? Moderate? Plaque location? LAD more significant than circumflex? More questions raised than answered, unfortunately.
Also, I don’t know how much credence I would place on diagnostic criteria from data gleaned in 1880 - their diagnostic tools were fairly limited. As usual, all this stuff has to be taken with a grain of salt. Also, CT/MRI data from mummies is questionable since the mummified state will alter the plaque burden seen on the scan.
This made me wonder how prevalent AS and CVD is in the animal kingdom at large. Is there data for hominids, or even ruminants and predators, living in the wild right now? Would love to see how that correlates to the current and historic human data.
Can you do a video about a2 milk?
Interesting thanks !
My 2c:
1. In ancient times, only the most wealthy people had their body preserved and mummified. Most probably, those wealthy folks were not physically active.
2. Unangans nutrition was primarily based on fatty fish and meat.
The calcified arteries of Otzi the ice-man are very intriguing!
A fascinating explanation of the weaknesses of population studies. What interests me is the nearly unique susceptibility of humans to heart disease. I think thee are a number of proposed explanations, any of which might be true. But one observation I think holds: evolutionary pressure to overcome this susceptibility is minimal because most humans reproduce before reaching the age where heart disease becomes a major risk.
That doesn't mean we can't do anything about it. But we need to be aware of our weaknesses.