Pharmacopore features can be obtained from different sources like LigandScout, Schrodinger, ... Furthermore, you can decide your descriptors based on Lipinski's role of five or in the case of Fragment-based Drug discovery role of 3. I am about to make a comprehensive step-by-step tutorial of Pharmacophore-based drug discovery.
I usually use galaxy Europe, LigandScout, and CavityPlus. I will have tutorials of these tools very soon. Please see my paper in www.futuremedicine.com/doi/10.2217/fvl-2020-0394
![[Sub Thai] APT. - ROSÉ & Bruno Mars](http://i.ytimg.com/vi/bYjhzP8x_uc/mqdefault.jpg)
👍
From where do you get the features? How do I decide about the descriptors?
Pharmacopore features can be obtained from different sources like LigandScout, Schrodinger, ... Furthermore, you can decide your descriptors based on Lipinski's role of five or in the case of Fragment-based Drug discovery role of 3. I am about to make a comprehensive step-by-step tutorial of Pharmacophore-based drug discovery.
PLEASE i need more explanation for rule of Three
How did you get the pharmacophore class, XYZ, Radius info? please
I usually use galaxy Europe, LigandScout, and CavityPlus. I will have tutorials of these tools very soon. Please see my paper in
www.futuremedicine.com/doi/10.2217/fvl-2020-0394
@@al1r3z49 thank you so much for your response 😊🙏
fROM WHERE THE XYZ AND RADIUS DATA CAN OBTAINED
You can use CavityPlus web server