Historys Weirdest Experiments
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- เผยแพร่เมื่อ 27 ก.ย. 2024
- Discover the 5 Weirdest Experiments in History! From LSD-laced elephants to two-headed dogs, these bizarre trials pushed boundaries and advanced science, some with tragic outcomes. Plus, meet Werner Forssmann, the daring scientist who risked his life to revolutionize cardiology!
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In a sea of unethical experiments, you gotta respect the one scientist who chooses to experiment on himself.
I suppose it beats the alternative, but its still discouraged.
@@vic5015 Especially when the consequences of being wrong would be death.
You know he tried that on animals first right?
Cadavers at least
i get guardians 3 flashbacks. what is the oath of hippocratus? i love science, there are lines that not even i will cross.
An experiment that proves it's hypothosis wrong is not a failed experiment, it is a successful one. A failed experiment is only one that doesn't answer the questions it's designed to.
Even then it's not necessarily failed (well, in the grand scheme). If you're trying to determine whether a specific animal secretion can cure epilepsy and instead discover that the secretion is developed through a unique interaction with the creature's environment, and that discovery leads to zoological breakthroughs, that's kind of cool.
Couldn't have said it better myself. Really reminds me of "the difference between science and messing around is writing down the results"
In the words of one Adam Savage "Failure is always an option"
Sounds like equal parts truth and cope, but I can't deny that there is still merit in an experiment not acheiving the intended result; Knowing where your goal is not is just as important as knowing where it is.
There was a certain socio-linguistic experiment involving a dolphin, lady and a lot of LSD. It would probably deserve its own episode.
Yeah, all that and the "lady" lived with the male dolphin and often gave him handy J's to make the mammel more comfortable. Definitely a weird time and experiment that deserves its own episode.
Done to death
DOA.
@@Woody_Florida Except she didn't, that was a story that was entirely embellished by tabloids of the time.
Wasn't that a Last Podcast on The Left episode?
Imagine being sentenced to execution and a scientist walks into you cell and tells you they think you will still be alive after your head is decapitated. Whether you agree to help or not, it must be terrifying to have that conversation.
Scariest part is, you would be.
There's a lesser known C.S. Lewis book called That Hideous Strength, where this happens
Lesson learned: if you succeed, you are celebrated, no matter how messed up the experiment, but if you fail, you're condemned for eternity
Yup. So if you decide to throw ethics by the wayside, always double check your math and be as sure as you possibly can that you're correct
The dog head transplantation/ revival videos is the most uncomfortable I've ever been during a Whistlerverse video, and I've binged all of his Casual Criminalist videos.
yeah it kinda scarred me for life lol... and I've seen some really sick shit on the internet when I was younger...(I've seen worse, like cartel executions, the infamous Russian soldier beheading videos, and a video where a man somewhere in Asia wrecked his motorbike, flew off the bike, and his torso being severed by a lamppost....the video was extremely graphic and the man lived for far too long, even going as far as trying to shove his own intestines and guts back into his body...I still remember the steam rising up from the gore, and crowds of morbid people surrounding him snapping pictures etc...I wish hadnt seen any of them now in my 30s....)
Demikovh was not the only surgeon practising unethical operations on animals. I'm astonished that Simon didn't put the case of Dr. Robert J. White in the video. He transplanted the head of one monkey to the body of another one in 1970!
Was a bit much for me. I was honestly disgusted.
Same tho😊
1:10 - Chapter 1 - Elephants on acid
4:40 - Chapter 2 - 2 headed dogs
7:45 - Chapter 3 - Dogs back from the dead
10:55 - Chapter 4 - Blinking after beheading
15:00 - Chapter 5 - Stabbing yourself in the heart
Ty :)
"Despite their elephants" had me absolutely crying😂😂 thanks for another great video Simon.
WOW 10:00 I'm so disappointed
Holy crap-
3:05
Had to go back and check I heard it right.
“are my ears also dyslexic or did that happen” was my first thought 😆
I think he had elephants on the brain lol
Elephants have absolutely massive brains though, and they had no idea how the rest of their biochemistry would react to LSD, that entire thing sounds like the worst kind of "Let's do this and see what happens!"
They could have considered the alternative: Start with a low dosage and then work their way up in small increments.
That death is the only known death from LSD ever recorded AFAIK. There was no reason for them to give that elephant that much. The dose is in MICROGRAMS per kilogram, not mg/kg.
In fact, studies in humans have since found that the LOWEST concentration of LSD in the body after it is ingested is in the brain, and it that for humans at least, it is no longer detectable in the brain hours before the effects stop.
@@kaltaron1284I suspect they had limited time with the elephant, no one is that irresponsible without s motivation
@@Puerco-Potter Hubris and negligience will suffice. But yes, maybe they had time costraints which should have led them to not do it.
I wonder if one of them said hey I wonder if Dumbo can really fly
I should thank Werner Forssman. I recently needed bypass surgery, and who knows what would have happened if he didn't pave the way. Thankfully, I'm doing much, much better now.
If this was a Brain Blaze to "Was the torture to 44 dogs worth it for the thousands of human lives saved?" Simon would say "Yes, of course it was. Humans are superior!"
Well, human beings are the only animals the even try to help things they have never encountered after all
@@ReddFoxx1562 this is not true we have seen altruism in many species and not just specific to there own
@@Danielhuren that's not what I said. I said there hasn't been an animal other than humans that have helped things that they will never encounter in life. You can show me all the nice fuzzy examples of animals helping other animals, but they're not putting yourself at risk or doing anything for things that are literally on the other side of the planet that they will never meet. People do though
@@ReddFoxx1562 there are cases of animals literaly adopting humans and protecting them your still wrong
@@Danielhuren you are still referencing something that requires direct contact and direct interaction with whatever they're helping. I am not saying that what you are saying never happens oh, I'm just saying that no animal other than humans ever helps animals or environments or anything that they do not directly encounter. I've explained this pretty clearly several times by now, if you don't get it then I guess you just don't understand what I'm saying
Dosing at .2 to .3 milligrams per kg seems pretty high. I'm pretty experienced with using LSD. Doses are expressed in micrograms, not milligrams. Blotter tabs are usually dosed at 75 to 125ug well above what a threshold dose would be
200-1000 ug sounds more like the 60's
For a 70kg man that would be 7000 ug, so WAY too much. This is just plain wrong in the video
Yep, 0.2mg to 0.3mg total would be a strong dose for humans. The claim of that being a "per kg" dose is a dangerous piece of misinformation. Hopefully these idiots fix it before someone uses this video as a reference for how much lsd to take. You would think we'd all know the importance of verifying our fucking units of measurement by now.
Ah yes finally I find it. I am a doctor, pharmaceutical scientist and lover of lsd in my early days before medical school. You are correct. He meant to say just 0.2 to 0.3 mg aka 200 to 300 micrograms total. Not mg per kg lol it's like his editor couldn't even believe the potency 😅
LSD is based on the amount of the drug not the body weight of the imbiber. The most I've ever taken was around 450mcg. It freaking leveled me. I did amazingly well at Jenga that night.
Not gonna lie some scientists in this video deserve to be flayed. To understand the science behind it, of course.
There a lot of that shit going on today. Not letting something blink or sleep can only be done for some many fucking decades. We're still doing it to animals though. For science... or some fucking lie.
I second this
The last point on the heart catheters is actually what saved my dad's life at least for a while. It's really cool to learn about the guy that made that possible!
Brilliant!!! I go into cathlabs often in my job and it’s nice to learn how our modern medical practice was pioneered.
>Grafts 2 dogs together
>People start complaining that its unethical
Demikov:🗿
The two-headed dog experiment is one of the most cruel experiments I've ever heard of. Imagine being anaesthetized and then just waking up with the lower half of your body gone, and you're sewn to another person like something out of a fucking horror movie. And those dogs couldn't understand what was going on.
I'm glad that we have so much knowledge today, but some of these "scientists" were literally just psychopaths using "research" as an excuse to do insane shit
Imagine being able to heal para and quadriplegics by transplanting their head onto another body.
Where do you start research?
@@DawidUliczny-ro7eo there's no scenario in which you'd need to keep both heads alive at the same time
The canine centipede?
As much as I agree. Things like this can also lead to learning and massive breakthroughs. It's the fine line between ethical and moral standards and what humans are willing to do to discover a species changing medicine like antibiotics or something or fixing paralyzed people
You said "despite there elephants" instead of "despite there efforts" during the tusko part lul love you Simon
"there" elephants? not "here" elephants?
@@peterbaldwin4037their*
RIP tusko
He died how he lived
High
Can't help but think that the Tusky and the two-headed dogs suffered needlessly, meaning the knowledge gained wasn't commensurate to their suffering. At the very least, the experiments could have been better designed to "discover" the same things without the unnecessary suffering and death. At least we came out with the wonders of CPR and cardiac catheterization with the other experiments. This is probably why I felt more for the animals than the human test subjects discussed. What they did to Tusky and the two-headed dogs is almost like the "science" done by Mengele out of idle and cruel curiosity without the rigor and actual benefit to society.
Yeah, it doesn't seem like tge guy tried very hard to prevent the rejection and possibly keep the dogs alive...just kept doing the same thing again and again.
That death is the only known death from LSD ever recorded AFAIK (maybe there's like one more or something) There was no reason for them to give that elephant that much. The dose is in MICROGRAMS per kilogram, not mg/kg.
In fact, studies in humans have since found that the LOWEST concentration of LSD in the body after it is ingested is in the brain, and it that for humans at least, it is no longer detectable in the brain hours before the effects stop.
I disagree with Demikhov's experiments with tissue rejection. I've been obsessed with his work since I was a kid, and it surprisingly ended up saving my life.
I just had an organ transplant 3 years ago, and my body still rejected the foreign tissue multiple times, and I was almost allowed to die before a final shuffling of my medications and a fifth shunt being meshed into my guts. We still have a long ways to go with organ transplants, and there's no other way to improve than by experimentation, which is still ongoing, just now with human subjects. I'm a willing one now, since rejection is just a part of my life now, so I have no idea how long I've got until I just get confused one day and don't come out of it, and I'm barely 30. My latest stint in the hospital when my body decided to turn on my kidneys (not even my transplanted organ) was two weeks ago, and the only reason I didn't die of that was because a friend checked in on me and found me unconscious and covered in freaked-out, hungry dogs. 😂
His repeated attempts, which did improve significantly with observation and making adjustments and introducing new methodology each time, saved countless human lives and jump-started the entire field. His plans were short-sighted and brutal, but still extremely useful. And trust me, I've dwelled on it a lot, since dogs are literally my life.
I love animals. Have a channel dedicated to them. However the two headed dog experiment laid the foundation for organ transplant. And now saves lives every day. BUT the elephant thing was just purely irresponsible. Poor thing didn't deserve to OD. All that experiment proved was how much LSD is deadly to elephants.
As a fellow animal lover, it was difficult to see the faces of the dogs who went to sleep and then woke up with another dog attached to them. That German Shepherd, especially!
They also sent a dog to space without any return plans... That's just as cruel.
The two headed dog experiment was definitely Frankensteinian, (new word?). Perhaps the ultimate aim was to transplant a healthy head from an unhealthy body to extend the life of an important individual like a scientist for example. Imagine if they could have transplanted Stephen Hawking's head onto a new body? And although he lived a long time could he have achieved even more than he did? He might not be the best example. One better example might be William Clifford, a brilliant mathematician who proposed that matter results from curvature in space and that gravity is a natural consequence of this curvature - one of the key concepts in Albert Einstein’s general theory of relativity. He died at the age of 33 of tuberculosis. What might he have done if he had lived?
how close are we to disembodied head in a jar?
With modern technology, with retinal movements use to interface with computers, we could probably get a great deal of info from a decapitated head that would allow possible communication of complex thoughts through said interface.
That last one is incredible, I was a nurse in the trauma ICU where I assisted in these, I had no idea that the guy who started it did it to himself
I remember seeing a chicken head after decapitation. The eyes blinked a few times. It was kind of gruesome.
# 3: Isn't the conundrum for this similar to the conundrum of using the scientific/medical info gleaned during WWII by the Nazis ?
LSD doses are measured in micrograms(µg/mcg), not milligrams(mg). .2 mg/kg would mean 16000µg for a person weighing 80kg or about 100 times what most people would consume to trip on it(tabs are commonly around 100-300µg).
I think the ends can justify the means, the trouble is you can't use that as justification because you have no idea that the ends will justify the means. It's more, in retrospect, we can argue the means had some justifications.
That is exactly why the end never justifies the means. You just did it and hoped that the result would be worth it. That isn't acting ethically, it's chance. You always have to make sure that even if all fails, you did right by people.
The two-headed dog sounds much like something from Michail Bulgakovs 'A Dog's Heart' novel.
You know it’s odd that all these doctors are similar characteristics to how they say you recognize psychopaths. Cruelty to animals.
*Yes just like "DIGBY" the world's biggest dog 😊👍*
Experiments don't fail. They always give you an answer.
You said .02-.03 but the graphic showed .2-.3
I'm honestly shocked that Cornish's work didn't attract the attention of a certain mustached man and his posse
I'm a person that believes that the ends do justify the means. It's a simple balance equation of if you did more good than harm then the event is good
However, that does not mean that you can be reckless. An attempt to mitigate harm as much as possible does need to be made
Also, such a stance does not forgive the people carrying out these tasks unless they were wholeheartedly trying to benefit the greater good
Cornish's Lazarus experiments sound eerily like the plot of Pet Sematary. I wonder if King was aware of them.
Simons moral high ground is exhausting
Just to note:
A dose of 0.2 mg - 0.3 mg per KG of bodyweight for LSD would be an astronomical dose for a human.
The standard dose range would be roughly 0.075 mg/75ug (micrograms) - 0.4mg/400ug IN TOTAL. There are obviously some outliers depending on experience etc.
A person weighing 70kg taking 0.2mg per kg would dose at 14,000ug.
That dose would result in almost certain severe psychosis, probably PTSD, HPPD, a very long hospital stay for 99.5% of people for sure and you would never ever come back the same person.
I dread to think what that poor elephant went through 😣
A dose of 297,000ug is absolutely insane overkill, even for an animal that size.
Tusko must have gone out tripping absolute balls though.
7:18 a complex fusion of dogs as well.
“How much acid, Dr West?”
“I don’t know, just fuck him up fam”
CIA: “SIGN HIM UP”
Weird semantic observation that I liked. "Can the ends validate the means" vs "Can the ends justify the means"
I'm sorry Simon even though I subscribe to all your channels I cannot finish watching this video I love animals too much
Well after those dog stories I’m going to need some time with my doogs to clear away the dark stain that the stories left.
“Unfortunately, despite their elephants, Tusko did not recover” amazing slip of the tongue there Fact Boi
A common dose of LSD would be 3 micrograms a kilogram, not .2-.3 (200-300 micrograms) milligrams a kilogram, although an active dose of LSD can be as low as 1 microgram a kilogram.
In other words, 70 micrograms of LSD would produce noticeable effects in a 70 kg man.
From the Tusko experiment, it seems body weight is not the thing to measure against, rather an estimate of the weight of the nervous system might be better.
Lazarus dogs, pavlovs dog, insulin dogs, two headed dogs, dogs in space. If dogs are mans best friend, what's dogs biggest enemy?
Insulin dogs? I’m not familiar with that, and being a type 1 diabetic I’m afraid to know. 😢
@@smooshiebear80 They figured out the relationship between blood sugar, insulin, and diabetes by experimenting on living dogs. That's how both you and I can live somewhat normal lives as type 1's. It's horrible to think about, but I for one am glad I'm not literally puking to death with ketoacidosis. I love dogs, so I'm glad they did all that before my time. Otherwise I would have not felt it was worth those poor doggo's lives.
Goddrick the grafted energy from that guy
Watching this with my dog next to me was unsettling 😢
Bro after hearing this, helping science or not...we are unworthy af of such good creatures😢
@@mastathrash5609Very true
7:18. Seems to be a complex fusion of dogs as well.
I know this is a little late but I just wanted to point out the error in wording in the beginning of the video. You said that they were psychotropic drugs but the term for it, used in anything but a microdose, is actually a psychedelic drug. Tropic is brain enhancing, psychedelic induces hallucinations
I'm just amazed the transplanted head gained consciousness, after being detached from its body. I wonder if it would work with a detached human head being grafted onto a human body?
I do love to hear the unethical and macabre experiments in a morbid sense but I can't imagine anything like these experiments happening in modern times. It feels more like a circus of the past.
I'm surprised the attempts at a talking dolphin experiments weren't covered in this video
I don't like it when people speak of animal rights. The concept of rights is unique to humans. In nature there is no right to anything. If the stronger animal wants to kill you you can't say you have any rights or make demands. Kill or be killed, eat and be eaten.
Very good point. 👍🏼
When we were be trained on blood chokes for hand to hand combat in the Marines, we were taught that when done correctly, unconsciousness is achieved in 3-5 seconds. Clinical death in 8-13.
He also created 20 no headed dogs
Skipping the two-headed dog videos because I’m getting physically ill
0:00: 🐘 A study in 1962 attempted to replicate the aggressive behavior of elephants during mating season by administering a high dosage of LSD to an Indian elephant named Tusco, but tragically Tusco overdosed and died.
3:19: 💉 The experiments discussed involve high doses of LSD and the creation of two-headed dogs through organ transplantation, highlighting the dangers of reckless drug administration and the ethical implications of scientific exploration.
6:36: 🐶 The experiments of Dr. Demikov and Dr. Cornish involving dogs were ethically controversial but contributed to scientific progress in organ transplantation and resuscitation.
10:21: 🔬 The article discusses the controversial scientific experiments conducted by Cornish and Burrow on animals and humans, respectively, to explore the persistence of consciousness after death.
13:10: 🧠 The experiment on post-decapitation consciousness by Burrow remains controversial, with no concrete answer on whether the decapitated head retains consciousness or sentience.
16:14: 💡 Werner Forsman's pioneering experiment of inserting a catheter into his own vein laid the foundation for cardiac catheterization.
Recap by Tammy AI
2:20 0.2-0.3 milligrams per kg is incorrect. From what google tells me, a usual dose is around 100 micrograms (not per kg). 100 micrograms is 0.1 milligrams. Later it's stated they started big by giving the elephant 0.1 milligrams per kg. If that was starting big, the original figure is obviously wrong.
Also, the overdose potential for humans is pretty low. According to Wikipedia there have been no known overdosed deaths, and in 2015 a 49 year old woman survived a dose of 55 milligrams without any ill effects. About 550 times the normal dose.
There was also a case of 8 individual who took exceedingly high doses of LSD thinking it was cocaine. They had a plasma level of 1000-7000 micrograms per 100ml.. considering a person has around 5l liters of blood, and plasma is 55%, that's about 27.5-192 milligrams.
i despise the youtube algorithm, i with it would go away
Things have only gotten worse. RIP fouci beagles.
I've only ever chopped off the heads of chooks prior to preparing them for dinner but I have never seen a chook not blink. Not only did they blink but they seemed to be every bit aware as before their decapitation. I find it logical to believe that a person can still be aware for an unknown time after decapitation. How long would depend upon blood loss and how much oxygen was in their blood and therefore in the brain cells at that time. To state consciousness cannot continue flies in the face of reality and anecdotal evidence of those who have seen this phenomenon with their own eyes.
1:02 elephants on acid
4:34 two-headed dogs
You should do a part 2
How would the head have called out to the observing scientist? Assuming something went wonky and the cut was far enough down to include the laynx somehow there'd still be no way to push air through it to make sounds.
The head was supposed to communicate by blinking, not talking.
Ellis D. My hero.
Yeah I started with a cheeky half a fragile, didn't feel anything, had another cheeky half, still nothing so I took a whole one, still nothing, then I stood up and started walking, I felt my self be thrown backwards out of my body and I thought I died, I could see myself walking along like I was floating behind myself and the rest of the evening just got more and more interesting, only problem was I started my my first ever job the next morning, I made it in but that was one long day.
Circa 1990, at least, there was a Museum of Surgery in Moscow that contained a preserved specimen of one (or is it two?) of Demikhov's dogs, Seriously disconcerting.
Simon,
After seeing the thumbnail for this episode, no way am I going to watch this!
The Two headed dog one I’ve known about but it makes me sick I wish that man would have been put in prison for the rest of his sick life
“Unfortunately despite their elephants….”
Um, I think you mean efforts mate 😂
Ok, I did a lot of acid in the late 70's and 80's. To give an elephant that much in a "controlled environment"...Jesus. What hubris.
In the town I grew up in, there was a Lavoisier boulevard. And the last name Languille means "the eel" in english and is pronounced "Lhanguiye (L-han(as the sound we make when we want someone to repeat but the H is silent: HAN?)-gui(as in the word "GUIlt)YE(as in YEah). Lhanguiye
Story is of an Indian Elephant but the B role footage is of African Elephants. Big brain here
Despite their elephants, tusks did not recover! Lmao
@3:04 "Despite their elephants."
The third guy sounds like the dude from "the Reanimator" movies.
Glad you ended on a high note there Simon! Phewww...
this just shows us how far people are willing to go in the name of science im not saying thats bad or good im just stating the obvious ...
10:00 ethics stoped this?
Huh? That's like saying how far we are willing to go in the name of religion, or love, or just plian old sex (and how much farther for kinky sex?) --- We'll DO ANYTHING. We'll go ANYWHERE. We're so fucking bored. All we need is time.
The two headed dog is a thing of nightmares.
I put off watching this for a week because I was *obsessed* with Demikhov's experiments when I was younger, and I can't handle hearing misinformation about them without being able to properly respond. But this was done fine!
Like I said, I was super interested in his experiments with the dogs and working with tissue rejection, and now that I'm older I have mixed feelings. I'm actually an organ transplant recipient, so without his early work I might not have lived past 25.
But the deeper implications of our ability to control life and death with such archaic techniques fascinated me as much as his abuse of dogs horrified me (dogs have been my raison d'etre since childhood).
So yeah, on the one hand, absolutely monstrous experiments and vivisections. On the other, insanely useful results that I'd be dead without. If I had been the only person saved by a transplant I'd be devastated by the pointless waste of canine life, but as it is, I can't at all give an opinion.
The Lazarus Dogs, on the other hand, had no place being abused and thrown away like that. Every tiny bit of information gleaned from that series of "experiments" (AKA pointless slaughter of animals) could have been learned in other ways.
3:05 Despite their elephants
During the part about the 20 some 2 headed dogs a ad interrupted for Rover the dog food brand. Can't make this stuff up.
hi
i have conflicting feelings that some of these experiments generated valuable enough knowledge to save the lives of generations after
Someone once said (not the exact quote): There’s no such thing as bad science, only bad intentions. To be a good scientist you must willing to go further than anyone else.”
Well DUH. Science us literally hypothesis for why shit works and then testing it. Of fucking course its the hoddamn border. Otherwise it's already learned and no longer a fucking border. Ludicrously stupid.
Is this the same genius who said his keys were in the last place he looked?????
the script for this video was shockingly bad
Look, I'm gonna need 300mg of lsd. Don't ask.
These scientists made their nightmares real.
the Russian experiment where they hooked up the head of a dog to tubes and machinery and actually got the head to react to stimuli (running a feather across it's nose, to which it reacted, got it to do things a normal dog would do) is probably the craziest and most memorable/sickening I've ever seen. (Not sure if it's in this video, but the video is on TH-cam if you can stomach shit like that...) anytime a severed head that's still "alive" is pretty unsettling to me. Executioners from way back in time have written about heads opening their mouth to scream,or looking around/blinking, reacting to hearing noises like snapping your fingers etc.....that shxt has got to be the worst way to go...
Despite their 'elephants', Tusko did not recover 😂 I'm saying elephants in place of efforts from now on
Despite their elephants? I think you mean efforts...
Have you heard the song two headed dog. Roky Erickson
You absolutely are conscious shortly after a beheading, nothing in the process other than shock could instantly kill a man... The head cleanly cut retains enough oxygen in the blood already in there
... What would stop you being conscious other than shock? Which only happens say, half the time
What do you mean by shock? And would that imply that someone who’s neck had been broken during hanging is still conscious for several seconds?
Isnt 0.2mg per kg stupidly high for acid? I thought it wouldve been measured in Mcg.
That dude who stabbed himself in the heart to prove it was a fucking badass.
Haha "Despite there elephants Tusco did not recover." Haha I wonder if he noticed he said elephants instead of efforts.
You know it's going to be a wild experiment if it is named after something in the Bible.