An experiment that proves it's hypothosis wrong is not a failed experiment, it is a successful one. A failed experiment is only one that doesn't answer the questions it's designed to.
Even then it's not necessarily failed (well, in the grand scheme). If you're trying to determine whether a specific animal secretion can cure epilepsy and instead discover that the secretion is developed through a unique interaction with the creature's environment, and that discovery leads to zoological breakthroughs, that's kind of cool.
Sounds like equal parts truth and cope, but I can't deny that there is still merit in an experiment not acheiving the intended result; Knowing where your goal is not is just as important as knowing where it is.
Imagine being sentenced to execution and a scientist walks into you cell and tells you they think you will still be alive after your head is decapitated. Whether you agree to help or not, it must be terrifying to have that conversation.
Elephants have absolutely massive brains though, and they had no idea how the rest of their biochemistry would react to LSD, that entire thing sounds like the worst kind of "Let's do this and see what happens!"
That death is the only known death from LSD ever recorded AFAIK. There was no reason for them to give that elephant that much. The dose is in MICROGRAMS per kilogram, not mg/kg. In fact, studies in humans have since found that the LOWEST concentration of LSD in the body after it is ingested is in the brain, and it that for humans at least, it is no longer detectable in the brain hours before the effects stop.
Yeah, all that and the "lady" lived with the male dolphin and often gave him handy J's to make the mammel more comfortable. Definitely a weird time and experiment that deserves its own episode.
Forssman is indirectly responsible for saving my life. A few years ago I needed a PICC (upper arm to heart tube) so I could receive nutrients directly into my blood when my digestive system failed. Other than sepsis (they think kidneys) and a long slow recovery, I am back to my usual (sick and disabled but at home) self. I can even survive purely on oral food for now 😊 None of this would have been possible without him. And my kids would be without one of their parents. I cannot express how grateful I am! The doctors, nurses, cleaners, hosts, cooks, radiologists, dieticians, pharmacists, students, assistants and everyone else who saved me are incredible. I’m so glad I got to say thank you to them 😊
Wow! You have certainly been thru it. I had a picc line back in 1999, due to endocarditis. Was in the hospital for 50 days, on IV antibiotics. But at the time, I had no family worrying for me, or needing me. I was an IV drug user, and caught a bug on a heart valve. Luckily, it was caught early enough to save my life, or having to have heart valve replacement surgery. I went on to straighten up and have a child that is about to gain her BA degree. None of this would have happened w/o the IV antibiotics, and the ease of care afforded by having this access. So much of science (several fields) seem utterly barbaric. And much of it, unfortunately, is. It’s hard to see the good when the evil or cruel is so current. No body remembers these experiments. And that’s how it goes. The names of those that sacrificed are typically barely footnotes, unfortunately. And let’s not even start with Japanese studies, or Nazi studies…those are just disgusting. But the benefits have at least been put to good use. Although I doubt that the victims of these experiments would have gladly volunteered…
@@notaQuackhead369 i understand the concept of the best for the many, but I still struggle with the ethics of those actions. I think it’s okay to be grateful *and* be concerned about animal welfare. With regards to eating animals, if you eat other mammals I don’t see how dogs are any different, only two things I can think of is we tend not to eat many carnivores (higher risks of contamination because of the food chain: eg. How large fish have higher heavy metal content than smaller fish. Also they tend to be harder to farm as they have a higher risk of killing young/sick animals nearby and engaging in cannibalism, as well as posing a risk to smaller livestock in neighbouring areas) and that they aren’t very large unless you are breeding Great Danes, so the quantity of meat is pretty small. I have a dog I love very much, but I have also met adorable cows I would love to keep as a friend, had some really personable pet fish, and met some adorable lambs and sheep… and I really adore pigs too, and chickens are cute… I can’t be vegan anymore because my digestive issues mean I’m not able to easily get all my nutrients as it is, without making my diet even smaller. And tube feeding into the heart isn’t vegan either (officially: most vegans agree you can do whatever you need to, to save your life). So when I eat meat, dairy and eggs its mostly to try and get the nutrients I need rather than for enjoyment (I don’t really like most meats, stronger cheese nor do I like eggs that much tbh) but if I found a cut of meat that I could digest well and doesn’t have a texture that makes me feel sick, I don’t really care what animal it’s from as long as it’s safe.
@@terryenby2304 I’m sorry to pop in here, but I just wanted to interject that feeding tubes go into the stomach. And it hurts like a SOB getting them put in. Fish can have real personalities. Sadly, I’ve had to come to the conclusion that all animals have their pluses, and it’s nearly impossible to eat any unless you simply resign yourself to the luxury that we have in this society, of not having to kill and butcher our own meats. I don’t feel great about it. But my diet demands protein, and I’m poor, and I’m lazy. So, I eat meat. I’m sure I could be argued out of it. But I’d go back to it, cause I actually like meat. For a while I tried to only eat what I felt I could kill and butcher. Hence, I only ate fish and fowl. Which is a pretty healthy diet. But when you find yourself living on a fixed income, with about $42.00 a month for food, you better eat what you can get. Best diet I ever had, was when I was 19, living in NY. I bought 8 cakes of tofu for $1. Broccoli. A sack of rice. Soy sauce. That would last me for a week. It’s all in what you’re willing to sacrifice. And if you love animals enough, you can sacrifice your taste for them. Personally, I love meat. So I’m kinda screwed.
The dog head transplantation/ revival videos is the most uncomfortable I've ever been during a Whistlerverse video, and I've binged all of his Casual Criminalist videos.
yeah it kinda scarred me for life lol... and I've seen some really sick shit on the internet when I was younger...(I've seen worse, like cartel executions, the infamous Russian soldier beheading videos, and a video where a man somewhere in Asia wrecked his motorbike, flew off the bike, and his torso being severed by a lamppost....the video was extremely graphic and the man lived for far too long, even going as far as trying to shove his own intestines and guts back into his body...I still remember the steam rising up from the gore, and crowds of morbid people surrounding him snapping pictures etc...I wish hadnt seen any of them now in my 30s....)
Demikovh was not the only surgeon practising unethical operations on animals. I'm astonished that Simon didn't put the case of Dr. Robert J. White in the video. He transplanted the head of one monkey to the body of another one in 1970!
F for all the good boys that gave their life to save millions of peoples lives. And mad respect for the dude who decided to shove a catheter into his own heart!
I was in a terrible motorcycle accident, and had a severe pulmonary embolism from a large blood clot that travelled from my thigh into my lungs. They laid me on a table, stopped my heart, and threaded a long catheter through my heart and into my lungs to inject a clot-buster directly into the clot. That was more than forty years ago, and I'm still Kickin' Chicken.
Until or unless there is a way to keep someone alive after decapitation, there would be no way for them to tell you they were still aware of their surroundings. That alone makes it a disturbing experiment because the results could never be verified.
I've performed hundred of LSD experiments on myself in various settings for science. Had to document what Jerry Garcia sounds like on LSD or what playing Super Mario World is like on LSD.
@@Woody_Florida Most intense trips were at a NASCAR race and a church service with people speaking in Tongues. Frightening experiences. The wilderness is the best setting rivaled only by jam band show.
The last point on the heart catheters is actually what saved my dad's life at least for a while. It's really cool to learn about the guy that made that possible!
I should thank Werner Forssman. I recently needed bypass surgery, and who knows what would have happened if he didn't pave the way. Thankfully, I'm doing much, much better now.
Dosing at .2 to .3 milligrams per kg seems pretty high. I'm pretty experienced with using LSD. Doses are expressed in micrograms, not milligrams. Blotter tabs are usually dosed at 75 to 125ug well above what a threshold dose would be
Yep, 0.2mg to 0.3mg total would be a strong dose for humans. The claim of that being a "per kg" dose is a dangerous piece of misinformation. Hopefully these idiots fix it before someone uses this video as a reference for how much lsd to take. You would think we'd all know the importance of verifying our fucking units of measurement by now.
Ah yes finally I find it. I am a doctor, pharmaceutical scientist and lover of lsd in my early days before medical school. You are correct. He meant to say just 0.2 to 0.3 mg aka 200 to 300 micrograms total. Not mg per kg lol it's like his editor couldn't even believe the potency 😅
LSD is based on the amount of the drug not the body weight of the imbiber. The most I've ever taken was around 450mcg. It freaking leveled me. I did amazingly well at Jenga that night.
If this was a Brain Blaze to "Was the torture to 44 dogs worth it for the thousands of human lives saved?" Simon would say "Yes, of course it was. Humans are superior!"
@@Danielhuren that's not what I said. I said there hasn't been an animal other than humans that have helped things that they will never encounter in life. You can show me all the nice fuzzy examples of animals helping other animals, but they're not putting yourself at risk or doing anything for things that are literally on the other side of the planet that they will never meet. People do though
@@Danielhuren you are still referencing something that requires direct contact and direct interaction with whatever they're helping. I am not saying that what you are saying never happens oh, I'm just saying that no animal other than humans ever helps animals or environments or anything that they do not directly encounter. I've explained this pretty clearly several times by now, if you don't get it then I guess you just don't understand what I'm saying
The question of “was the knowledge worth the cost” can only really be answered on 2 criteria . 1. Has it saved more life than it cost? And 2. Could this knowledge have been gained by better means at the time or a little later with a bit more oversight? Bonus question: is it really cool? Not that it makes the docs heroes but that’s what nuance is about. Puts an asterisk next to their work at the very least.
I would also add "how many lives would have been lost if this experiment had never happened" because I feel like people often forget about what could have been. Some experiments were horrible but necessary, and we could have ended up much worse without it. Of course that doesn't make what they did any more right, but this is a very nuanced thing.
Me: *Stands up a bit too fast, brain shuts down instantly.* Dude in a guillotine gets his head cut off: "The catastrophic loss of blood pressure means nothing to me." Yeah, somehow this doesn't sound right.
Can't help but think that the Tusky and the two-headed dogs suffered needlessly, meaning the knowledge gained wasn't commensurate to their suffering. At the very least, the experiments could have been better designed to "discover" the same things without the unnecessary suffering and death. At least we came out with the wonders of CPR and cardiac catheterization with the other experiments. This is probably why I felt more for the animals than the human test subjects discussed. What they did to Tusky and the two-headed dogs is almost like the "science" done by Mengele out of idle and cruel curiosity without the rigor and actual benefit to society.
Yeah, it doesn't seem like tge guy tried very hard to prevent the rejection and possibly keep the dogs alive...just kept doing the same thing again and again.
That death is the only known death from LSD ever recorded AFAIK (maybe there's like one more or something) There was no reason for them to give that elephant that much. The dose is in MICROGRAMS per kilogram, not mg/kg. In fact, studies in humans have since found that the LOWEST concentration of LSD in the body after it is ingested is in the brain, and it that for humans at least, it is no longer detectable in the brain hours before the effects stop.
I disagree with Demikhov's experiments with tissue rejection. I've been obsessed with his work since I was a kid, and it surprisingly ended up saving my life. I just had an organ transplant 3 years ago, and my body still rejected the foreign tissue multiple times, and I was almost allowed to die before a final shuffling of my medications and a fifth shunt being meshed into my guts. We still have a long ways to go with organ transplants, and there's no other way to improve than by experimentation, which is still ongoing, just now with human subjects. I'm a willing one now, since rejection is just a part of my life now, so I have no idea how long I've got until I just get confused one day and don't come out of it, and I'm barely 30. My latest stint in the hospital when my body decided to turn on my kidneys (not even my transplanted organ) was two weeks ago, and the only reason I didn't die of that was because a friend checked in on me and found me unconscious and covered in freaked-out, hungry dogs. 😂 His repeated attempts, which did improve significantly with observation and making adjustments and introducing new methodology each time, saved countless human lives and jump-started the entire field. His plans were short-sighted and brutal, but still extremely useful. And trust me, I've dwelled on it a lot, since dogs are literally my life.
I love animals. Have a channel dedicated to them. However the two headed dog experiment laid the foundation for organ transplant. And now saves lives every day. BUT the elephant thing was just purely irresponsible. Poor thing didn't deserve to OD. All that experiment proved was how much LSD is deadly to elephants.
As a fellow animal lover, it was difficult to see the faces of the dogs who went to sleep and then woke up with another dog attached to them. That German Shepherd, especially!
Wouldn't human-animal conversion rates for psychotropics be more accurate if we used brain weight instead of body weight? Body size doesn't always determine brain size.
You'd probably have to calibrate for both since if a subject has a relatively high brain:body volume ratio, the substance is more likely to end up highly concentrated in brain tissue.
Liver and kidney function for the animal will have a huge effect too. In humans of exact same body size and structure, if liver or kidney function is better or worse it will have a massive effect. Liver because it metabolizes the drug and kidneys because they determine how quickly it is filtered out.
With modern technology, with retinal movements use to interface with computers, we could probably get a great deal of info from a decapitated head that would allow possible communication of complex thoughts through said interface.
There is absolutely no possible way that a decapitated head called out in any way shape or form. Even if the cut were low enough on the neck to include the larynx, there are no lungs or other means to push air through and produce sound. It is physically impossible.
The two headed dog experiment was definitely Frankensteinian, (new word?). Perhaps the ultimate aim was to transplant a healthy head from an unhealthy body to extend the life of an important individual like a scientist for example. Imagine if they could have transplanted Stephen Hawking's head onto a new body? And although he lived a long time could he have achieved even more than he did? He might not be the best example. One better example might be William Clifford, a brilliant mathematician who proposed that matter results from curvature in space and that gravity is a natural consequence of this curvature - one of the key concepts in Albert Einstein’s general theory of relativity. He died at the age of 33 of tuberculosis. What might he have done if he had lived?
LSD doses are measured in micrograms(µg/mcg), not milligrams(mg). .2 mg/kg would mean 16000µg for a person weighing 80kg or about 100 times what most people would consume to trip on it(tabs are commonly around 100-300µg).
There a lot of that shit going on today. Not letting something blink or sleep can only be done for some many fucking decades. We're still doing it to animals though. For science... or some fucking lie.
Just to note: A dose of 0.2 mg - 0.3 mg per KG of bodyweight for LSD would be an astronomical dose for a human. The standard dose range would be roughly 0.075 mg/75ug (micrograms) - 0.4mg/400ug IN TOTAL. There are obviously some outliers depending on experience etc. A person weighing 70kg taking 0.2mg per kg would dose at 14,000ug. That dose would result in almost certain severe psychosis, probably PTSD, HPPD, a very long hospital stay for 99.5% of people for sure and you would never ever come back the same person. I dread to think what that poor elephant went through 😣 A dose of 297,000ug is absolutely insane overkill, even for an animal that size.
I'm a person that believes that the ends do justify the means. It's a simple balance equation of if you did more good than harm then the event is good However, that does not mean that you can be reckless. An attempt to mitigate harm as much as possible does need to be made Also, such a stance does not forgive the people carrying out these tasks unless they were wholeheartedly trying to benefit the greater good
I think the ends can justify the means, the trouble is you can't use that as justification because you have no idea that the ends will justify the means. It's more, in retrospect, we can argue the means had some justifications.
That is exactly why the end never justifies the means. You just did it and hoped that the result would be worth it. That isn't acting ethically, it's chance. You always have to make sure that even if all fails, you did right by people.
The two-headed dog experiment is one of the most cruel experiments I've ever heard of. Imagine being anaesthetized and then just waking up with the lower half of your body gone, and you're sewn to another person like something out of a fucking horror movie. And those dogs couldn't understand what was going on. I'm glad that we have so much knowledge today, but some of these "scientists" were literally just psychopaths using "research" as an excuse to do insane shit
As much as I agree. Things like this can also lead to learning and massive breakthroughs. It's the fine line between ethical and moral standards and what humans are willing to do to discover a species changing medicine like antibiotics or something or fixing paralyzed people
I watched the actual footage from the two headed dog and the back from the dead dog.... That is most uncomfortable I've been in a long time, seeing the clips again here a few years later just ugh. It's unsettling to say the least. They take a close second after viewing the old footage of a human with rabies..
2:20 that's wrong. The dose for humans is not 200-300 micrograms per kg, it's 200-300 micrograms TOTAL. Hopefully nobody ever uses this video as a reference for how much lsd to take, as ingesting 0.3mg per kg of bodyweight would be a colossal overdose. Lsd has detectable effects with as low as 10-20 micrograms in humans (total dose, not per kg).
Amazing the outcry when legitimate scientists, yes I love dogs and have 4 of them btw, do work that moves a field forward exponentially with their experiments and have helped save maybe hundreds of thousands if not millions of lives, yet most can't get past the those poor animals issue. And while I do agree that frivolous and needles experiments are terrible , like spraying perfumes in animals eyes, etc. But to move ourselves forward some martyrs have to be sacrificed. I've also noticed no one seems to care this much when the actual test subjects are humans. Unit 731 and Joseph mengela with the nazis are just 2 examples. Humanity is amazing... we love dogs and hate other humans... I'm sure there's some great irony in that statement. Simon you're the best and keep up the great work... YOU KNOW WHAT I'M SAYING PETER!
@@elijahgiter9559 Not the entire world, just some people. For them, it’s easier to commit atrocities when you don’t view the victims as human. They probably had a higher regard for dogs.
When we were be trained on blood chokes for hand to hand combat in the Marines, we were taught that when done correctly, unconsciousness is achieved in 3-5 seconds. Clinical death in 8-13.
I don't like it when people speak of animal rights. The concept of rights is unique to humans. In nature there is no right to anything. If the stronger animal wants to kill you you can't say you have any rights or make demands. Kill or be killed, eat and be eaten.
acid's measured in micrograms (1mcg=.001mg). hallucinations can start w/ just 40-75mcg (.04-.075mg). based on the calculation of .2-.3mcg/kg body weight, w/ a body weight of 175lbs, that measures out to 35-42mcg which matches up with the minimum hallucinatory threshold. based on your low dose calculation of ".2-.3mg" a 175lb person would be taking 35mg=35000mcg, meaning a maximum perceptual saturation dose that will be extended in duration as your body has to metabolize so much more. in average cases, 1.5-2mg (1500-2000mcg) doses last 12 hours, and every .01mg (100mcg) extends time by .5-1 hour. alternatively maybe your editor meant to write .2-3mg total as a full hallucinatory dose, as that is only slightly higher than a typical recreational dose... either way, viewers are fixin' to try your calculation and become personal friends w/ the void lmao
0:00: 🐘 A study in 1962 attempted to replicate the aggressive behavior of elephants during mating season by administering a high dosage of LSD to an Indian elephant named Tusco, but tragically Tusco overdosed and died. 3:19: 💉 The experiments discussed involve high doses of LSD and the creation of two-headed dogs through organ transplantation, highlighting the dangers of reckless drug administration and the ethical implications of scientific exploration. 6:36: 🐶 The experiments of Dr. Demikov and Dr. Cornish involving dogs were ethically controversial but contributed to scientific progress in organ transplantation and resuscitation. 10:21: 🔬 The article discusses the controversial scientific experiments conducted by Cornish and Burrow on animals and humans, respectively, to explore the persistence of consciousness after death. 13:10: 🧠 The experiment on post-decapitation consciousness by Burrow remains controversial, with no concrete answer on whether the decapitated head retains consciousness or sentience. 16:14: 💡 Werner Forsman's pioneering experiment of inserting a catheter into his own vein laid the foundation for cardiac catheterization. Recap by Tammy AI
I know this is a little late but I just wanted to point out the error in wording in the beginning of the video. You said that they were psychotropic drugs but the term for it, used in anything but a microdose, is actually a psychedelic drug. Tropic is brain enhancing, psychedelic induces hallucinations
Yeah I started with a cheeky half a fragile, didn't feel anything, had another cheeky half, still nothing so I took a whole one, still nothing, then I stood up and started walking, I felt my self be thrown backwards out of my body and I thought I died, I could see myself walking along like I was floating behind myself and the rest of the evening just got more and more interesting, only problem was I started my my first ever job the next morning, I made it in but that was one long day.
From the Tusko experiment, it seems body weight is not the thing to measure against, rather an estimate of the weight of the nervous system might be better.
A common dose of LSD would be 3 micrograms a kilogram, not .2-.3 (200-300 micrograms) milligrams a kilogram, although an active dose of LSD can be as low as 1 microgram a kilogram. In other words, 70 micrograms of LSD would produce noticeable effects in a 70 kg man.
In the town I grew up in, there was a Lavoisier boulevard. And the last name Languille means "the eel" in english and is pronounced "Lhanguiye (L-han(as the sound we make when we want someone to repeat but the H is silent: HAN?)-gui(as in the word "GUIlt)YE(as in YEah). Lhanguiye
How would the head have called out to the observing scientist? Assuming something went wonky and the cut was far enough down to include the laynx somehow there'd still be no way to push air through it to make sounds.
Huh? That's like saying how far we are willing to go in the name of religion, or love, or just plian old sex (and how much farther for kinky sex?) --- We'll DO ANYTHING. We'll go ANYWHERE. We're so fucking bored. All we need is time.
I do love to hear the unethical and macabre experiments in a morbid sense but I can't imagine anything like these experiments happening in modern times. It feels more like a circus of the past.
Circa 1990, at least, there was a Museum of Surgery in Moscow that contained a preserved specimen of one (or is it two?) of Demikhov's dogs, Seriously disconcerting.
Every experiment that "fails" contributes to our knowledge as much as the ones that succeed. Knowing what *isn't* the correct answer helps narrow the possibilities of what the correct solution is.
I'm certain all sociopaths rationalise those "failed" (code word for killing or permanently disabling) experiments on unwilling participants have the same insight that you have. That is the benefits they personally gained from these results were more than the price other people or animals paid.
I put off watching this for a week because I was *obsessed* with Demikhov's experiments when I was younger, and I can't handle hearing misinformation about them without being able to properly respond. But this was done fine! Like I said, I was super interested in his experiments with the dogs and working with tissue rejection, and now that I'm older I have mixed feelings. I'm actually an organ transplant recipient, so without his early work I might not have lived past 25. But the deeper implications of our ability to control life and death with such archaic techniques fascinated me as much as his abuse of dogs horrified me (dogs have been my raison d'etre since childhood). So yeah, on the one hand, absolutely monstrous experiments and vivisections. On the other, insanely useful results that I'd be dead without. If I had been the only person saved by a transplant I'd be devastated by the pointless waste of canine life, but as it is, I can't at all give an opinion. The Lazarus Dogs, on the other hand, had no place being abused and thrown away like that. Every tiny bit of information gleaned from that series of "experiments" (AKA pointless slaughter of animals) could have been learned in other ways.
@3:00 "unfortunately, despite their elephants, Tusko did not recover..." Simon made me snort with laughter at the death of an elephant. Now I feel bad.
Lol, the street I live on, a main thoroughfare, is abbreviated LSD. So when I or someone else texts or posts , “I was on LSD, and this jerk cut me off,” people sometimes react; “what?!” “No, the street.” It’s much more amusing in the moment - “ya had to be there.”
"I was on LSD and this assh*le pulled out in front of me" "I was on LSD and some f*** kept riding my ass" "I was on LSD and almost saw this massive pileup" Nice
2:20 0.2-0.3 milligrams per kg is incorrect. From what google tells me, a usual dose is around 100 micrograms (not per kg). 100 micrograms is 0.1 milligrams. Later it's stated they started big by giving the elephant 0.1 milligrams per kg. If that was starting big, the original figure is obviously wrong. Also, the overdose potential for humans is pretty low. According to Wikipedia there have been no known overdosed deaths, and in 2015 a 49 year old woman survived a dose of 55 milligrams without any ill effects. About 550 times the normal dose. There was also a case of 8 individual who took exceedingly high doses of LSD thinking it was cocaine. They had a plasma level of 1000-7000 micrograms per 100ml.. considering a person has around 5l liters of blood, and plasma is 55%, that's about 27.5-192 milligrams.
I've only ever chopped off the heads of chooks prior to preparing them for dinner but I have never seen a chook not blink. Not only did they blink but they seemed to be every bit aware as before their decapitation. I find it logical to believe that a person can still be aware for an unknown time after decapitation. How long would depend upon blood loss and how much oxygen was in their blood and therefore in the brain cells at that time. To state consciousness cannot continue flies in the face of reality and anecdotal evidence of those who have seen this phenomenon with their own eyes.
In a sea of unethical experiments, you gotta respect the one scientist who chooses to experiment on himself.
I suppose it beats the alternative, but its still discouraged.
@@vic5015 Especially when the consequences of being wrong would be death.
You know he tried that on animals first right?
Cadavers at least
i get guardians 3 flashbacks. what is the oath of hippocratus? i love science, there are lines that not even i will cross.
An experiment that proves it's hypothosis wrong is not a failed experiment, it is a successful one. A failed experiment is only one that doesn't answer the questions it's designed to.
Even then it's not necessarily failed (well, in the grand scheme). If you're trying to determine whether a specific animal secretion can cure epilepsy and instead discover that the secretion is developed through a unique interaction with the creature's environment, and that discovery leads to zoological breakthroughs, that's kind of cool.
Couldn't have said it better myself. Really reminds me of "the difference between science and messing around is writing down the results"
In the words of one Adam Savage "Failure is always an option"
Sounds like equal parts truth and cope, but I can't deny that there is still merit in an experiment not acheiving the intended result; Knowing where your goal is not is just as important as knowing where it is.
Imagine being sentenced to execution and a scientist walks into you cell and tells you they think you will still be alive after your head is decapitated. Whether you agree to help or not, it must be terrifying to have that conversation.
Scariest part is, you would be.
There's a lesser known C.S. Lewis book called That Hideous Strength, where this happens
Elephants have absolutely massive brains though, and they had no idea how the rest of their biochemistry would react to LSD, that entire thing sounds like the worst kind of "Let's do this and see what happens!"
They could have considered the alternative: Start with a low dosage and then work their way up in small increments.
That death is the only known death from LSD ever recorded AFAIK. There was no reason for them to give that elephant that much. The dose is in MICROGRAMS per kilogram, not mg/kg.
In fact, studies in humans have since found that the LOWEST concentration of LSD in the body after it is ingested is in the brain, and it that for humans at least, it is no longer detectable in the brain hours before the effects stop.
@@kaltaron1284I suspect they had limited time with the elephant, no one is that irresponsible without s motivation
@@Puerco-Potter Hubris and negligience will suffice. But yes, maybe they had time costraints which should have led them to not do it.
I wonder if one of them said hey I wonder if Dumbo can really fly
There was a certain socio-linguistic experiment involving a dolphin, lady and a lot of LSD. It would probably deserve its own episode.
Yeah, all that and the "lady" lived with the male dolphin and often gave him handy J's to make the mammel more comfortable. Definitely a weird time and experiment that deserves its own episode.
Done to death
DOA.
@@Woody_Florida Except she didn't, that was a story that was entirely embellished by tabloids of the time.
Wasn't that a Last Podcast on The Left episode?
1:10 - Chapter 1 - Elephants on acid
4:40 - Chapter 2 - 2 headed dogs
7:45 - Chapter 3 - Dogs back from the dead
10:55 - Chapter 4 - Blinking after beheading
15:00 - Chapter 5 - Stabbing yourself in the heart
Ty :)
Forssman is indirectly responsible for saving my life.
A few years ago I needed a PICC (upper arm to heart tube) so I could receive nutrients directly into my blood when my digestive system failed.
Other than sepsis (they think kidneys) and a long slow recovery, I am back to my usual (sick and disabled but at home) self. I can even survive purely on oral food for now 😊
None of this would have been possible without him. And my kids would be without one of their parents.
I cannot express how grateful I am! The doctors, nurses, cleaners, hosts, cooks, radiologists, dieticians, pharmacists, students, assistants and everyone else who saved me are incredible. I’m so glad I got to say thank you to them 😊
Can millions of lives saved be justified by a few dozen dogs dying? Um...I'd say so in the aspect some countries eat more than that on an hour
Wow! You have certainly been thru it.
I had a picc line back in 1999, due to endocarditis. Was in the hospital for 50 days, on IV antibiotics.
But at the time, I had no family worrying for me, or needing me. I was an IV drug user, and caught a bug on a heart valve. Luckily, it was caught early enough to save my life, or having to have heart valve replacement surgery.
I went on to straighten up and have a child that is about to gain her BA degree.
None of this would have happened w/o the IV antibiotics, and the ease of care afforded by having this access.
So much of science (several fields) seem utterly barbaric. And much of it, unfortunately, is.
It’s hard to see the good when the evil or cruel is so current. No body remembers these experiments. And that’s how it goes.
The names of those that sacrificed are typically barely footnotes, unfortunately.
And let’s not even start with Japanese studies, or Nazi studies…those are just disgusting. But the benefits have at least been put to good use.
Although I doubt that the victims of these experiments would have gladly volunteered…
@@mamapetillo8675 wow I’m so glad you are here to tell your story!
Agree with you :)
@@notaQuackhead369 i understand the concept of the best for the many, but I still struggle with the ethics of those actions. I think it’s okay to be grateful *and* be concerned about animal welfare.
With regards to eating animals, if you eat other mammals I don’t see how dogs are any different, only two things I can think of is we tend not to eat many carnivores (higher risks of contamination because of the food chain: eg. How large fish have higher heavy metal content than smaller fish. Also they tend to be harder to farm as they have a higher risk of killing young/sick animals nearby and engaging in cannibalism, as well as posing a risk to smaller livestock in neighbouring areas) and that they aren’t very large unless you are breeding Great Danes, so the quantity of meat is pretty small.
I have a dog I love very much, but I have also met adorable cows I would love to keep as a friend, had some really personable pet fish, and met some adorable lambs and sheep… and I really adore pigs too, and chickens are cute…
I can’t be vegan anymore because my digestive issues mean I’m not able to easily get all my nutrients as it is, without making my diet even smaller. And tube feeding into the heart isn’t vegan either (officially: most vegans agree you can do whatever you need to, to save your life). So when I eat meat, dairy and eggs its mostly to try and get the nutrients I need rather than for enjoyment (I don’t really like most meats, stronger cheese nor do I like eggs that much tbh) but if I found a cut of meat that I could digest well and doesn’t have a texture that makes me feel sick, I don’t really care what animal it’s from as long as it’s safe.
@@terryenby2304 I’m sorry to pop in here, but I just wanted to interject that feeding tubes go into the stomach. And it hurts like a SOB getting them put in.
Fish can have real personalities.
Sadly, I’ve had to come to the conclusion that all animals have their pluses, and it’s nearly impossible to eat any unless you simply resign yourself to the luxury that we have in this society, of not having to kill and butcher our own meats.
I don’t feel great about it. But my diet demands protein, and I’m poor, and I’m lazy. So, I eat meat.
I’m sure I could be argued out of it. But I’d go back to it, cause I actually like meat.
For a while I tried to only eat what I felt I could kill and butcher. Hence, I only ate fish and fowl. Which is a pretty healthy diet.
But when you find yourself living on a fixed income, with about $42.00 a month for food, you better eat what you can get.
Best diet I ever had, was when I was 19, living in NY. I bought 8 cakes of tofu for $1. Broccoli. A sack of rice. Soy sauce.
That would last me for a week.
It’s all in what you’re willing to sacrifice.
And if you love animals enough, you can sacrifice your taste for them.
Personally, I love meat.
So I’m kinda screwed.
The dog head transplantation/ revival videos is the most uncomfortable I've ever been during a Whistlerverse video, and I've binged all of his Casual Criminalist videos.
yeah it kinda scarred me for life lol... and I've seen some really sick shit on the internet when I was younger...(I've seen worse, like cartel executions, the infamous Russian soldier beheading videos, and a video where a man somewhere in Asia wrecked his motorbike, flew off the bike, and his torso being severed by a lamppost....the video was extremely graphic and the man lived for far too long, even going as far as trying to shove his own intestines and guts back into his body...I still remember the steam rising up from the gore, and crowds of morbid people surrounding him snapping pictures etc...I wish hadnt seen any of them now in my 30s....)
Demikovh was not the only surgeon practising unethical operations on animals. I'm astonished that Simon didn't put the case of Dr. Robert J. White in the video. He transplanted the head of one monkey to the body of another one in 1970!
Was a bit much for me. I was honestly disgusted.
Same tho😊
"Despite their elephants" had me absolutely crying😂😂 thanks for another great video Simon.
WOW 10:00 I'm so disappointed
Holy crap-
3:05
Had to go back and check I heard it right.
“are my ears also dyslexic or did that happen” was my first thought 😆
I think he had elephants on the brain lol
Lesson learned: if you succeed, you are celebrated, no matter how messed up the experiment, but if you fail, you're condemned for eternity
Yup. So if you decide to throw ethics by the wayside, always double check your math and be as sure as you possibly can that you're correct
F for all the good boys that gave their life to save millions of peoples lives. And mad respect for the dude who decided to shove a catheter into his own heart!
F
I was in a terrible motorcycle accident, and had a severe pulmonary embolism from a large blood clot
that travelled from my thigh into my lungs. They laid me on a table, stopped my heart, and threaded a long
catheter through my heart and into my lungs to inject a clot-buster directly into the clot. That was more than
forty years ago, and I'm still Kickin' Chicken.
Glad you're still here! :D
I reported this comment to PETA
Until or unless there is a way to keep someone alive after decapitation, there would be no way for them to tell you they were still aware of their surroundings. That alone makes it a disturbing experiment because the results could never be verified.
I've performed hundred of LSD experiments on myself in various settings for science. Had to document what Jerry Garcia sounds like on LSD or what playing Super Mario World is like on LSD.
I understand your need for knowledge in such areas.
Thank you for sacrificing yourself for the benefit of the rest of us
Such selfless acts in the name of science.
Truly worthy of the Nobel Prize
@@Woody_Florida
Most intense trips were at a NASCAR race and a church service with people speaking in Tongues. Frightening experiences. The wilderness is the best setting rivaled only by jam band show.
The last point on the heart catheters is actually what saved my dad's life at least for a while. It's really cool to learn about the guy that made that possible!
Brilliant!!! I go into cathlabs often in my job and it’s nice to learn how our modern medical practice was pioneered.
I should thank Werner Forssman. I recently needed bypass surgery, and who knows what would have happened if he didn't pave the way. Thankfully, I'm doing much, much better now.
Dosing at .2 to .3 milligrams per kg seems pretty high. I'm pretty experienced with using LSD. Doses are expressed in micrograms, not milligrams. Blotter tabs are usually dosed at 75 to 125ug well above what a threshold dose would be
200-1000 ug sounds more like the 60's
For a 70kg man that would be 7000 ug, so WAY too much. This is just plain wrong in the video
Yep, 0.2mg to 0.3mg total would be a strong dose for humans. The claim of that being a "per kg" dose is a dangerous piece of misinformation. Hopefully these idiots fix it before someone uses this video as a reference for how much lsd to take. You would think we'd all know the importance of verifying our fucking units of measurement by now.
Ah yes finally I find it. I am a doctor, pharmaceutical scientist and lover of lsd in my early days before medical school. You are correct. He meant to say just 0.2 to 0.3 mg aka 200 to 300 micrograms total. Not mg per kg lol it's like his editor couldn't even believe the potency 😅
LSD is based on the amount of the drug not the body weight of the imbiber. The most I've ever taken was around 450mcg. It freaking leveled me. I did amazingly well at Jenga that night.
If this was a Brain Blaze to "Was the torture to 44 dogs worth it for the thousands of human lives saved?" Simon would say "Yes, of course it was. Humans are superior!"
Well, human beings are the only animals the even try to help things they have never encountered after all
@@ReddFoxx1562 this is not true we have seen altruism in many species and not just specific to there own
@@Danielhuren that's not what I said. I said there hasn't been an animal other than humans that have helped things that they will never encounter in life. You can show me all the nice fuzzy examples of animals helping other animals, but they're not putting yourself at risk or doing anything for things that are literally on the other side of the planet that they will never meet. People do though
@@ReddFoxx1562 there are cases of animals literaly adopting humans and protecting them your still wrong
@@Danielhuren you are still referencing something that requires direct contact and direct interaction with whatever they're helping. I am not saying that what you are saying never happens oh, I'm just saying that no animal other than humans ever helps animals or environments or anything that they do not directly encounter. I've explained this pretty clearly several times by now, if you don't get it then I guess you just don't understand what I'm saying
You said "despite there elephants" instead of "despite there efforts" during the tusko part lul love you Simon
"there" elephants? not "here" elephants?
@@peterbaldwin4037their*
Well heck, thank you Werner Forssmann for laying the groundwork for the surgery that saved my life. ❤
The question of “was the knowledge worth the cost” can only really be answered on 2 criteria .
1. Has it saved more life than it cost?
And 2. Could this knowledge have been gained by better means at the time or a little later with a bit more oversight?
Bonus question: is it really cool?
Not that it makes the docs heroes but that’s what nuance is about. Puts an asterisk next to their work at the very least.
I would also add "how many lives would have been lost if this experiment had never happened" because I feel like people often forget about what could have been. Some experiments were horrible but necessary, and we could have ended up much worse without it. Of course that doesn't make what they did any more right, but this is a very nuanced thing.
Me: *Stands up a bit too fast, brain shuts down instantly.*
Dude in a guillotine gets his head cut off: "The catastrophic loss of blood pressure means nothing to me."
Yeah, somehow this doesn't sound right.
Doctor here. Refreshing and correct reasoning. Top marks.
Can't help but think that the Tusky and the two-headed dogs suffered needlessly, meaning the knowledge gained wasn't commensurate to their suffering. At the very least, the experiments could have been better designed to "discover" the same things without the unnecessary suffering and death. At least we came out with the wonders of CPR and cardiac catheterization with the other experiments. This is probably why I felt more for the animals than the human test subjects discussed. What they did to Tusky and the two-headed dogs is almost like the "science" done by Mengele out of idle and cruel curiosity without the rigor and actual benefit to society.
Yeah, it doesn't seem like tge guy tried very hard to prevent the rejection and possibly keep the dogs alive...just kept doing the same thing again and again.
That death is the only known death from LSD ever recorded AFAIK (maybe there's like one more or something) There was no reason for them to give that elephant that much. The dose is in MICROGRAMS per kilogram, not mg/kg.
In fact, studies in humans have since found that the LOWEST concentration of LSD in the body after it is ingested is in the brain, and it that for humans at least, it is no longer detectable in the brain hours before the effects stop.
I disagree with Demikhov's experiments with tissue rejection. I've been obsessed with his work since I was a kid, and it surprisingly ended up saving my life.
I just had an organ transplant 3 years ago, and my body still rejected the foreign tissue multiple times, and I was almost allowed to die before a final shuffling of my medications and a fifth shunt being meshed into my guts. We still have a long ways to go with organ transplants, and there's no other way to improve than by experimentation, which is still ongoing, just now with human subjects. I'm a willing one now, since rejection is just a part of my life now, so I have no idea how long I've got until I just get confused one day and don't come out of it, and I'm barely 30. My latest stint in the hospital when my body decided to turn on my kidneys (not even my transplanted organ) was two weeks ago, and the only reason I didn't die of that was because a friend checked in on me and found me unconscious and covered in freaked-out, hungry dogs. 😂
His repeated attempts, which did improve significantly with observation and making adjustments and introducing new methodology each time, saved countless human lives and jump-started the entire field. His plans were short-sighted and brutal, but still extremely useful. And trust me, I've dwelled on it a lot, since dogs are literally my life.
I love animals. Have a channel dedicated to them. However the two headed dog experiment laid the foundation for organ transplant. And now saves lives every day. BUT the elephant thing was just purely irresponsible. Poor thing didn't deserve to OD. All that experiment proved was how much LSD is deadly to elephants.
As a fellow animal lover, it was difficult to see the faces of the dogs who went to sleep and then woke up with another dog attached to them. That German Shepherd, especially!
That last one is incredible, I was a nurse in the trauma ICU where I assisted in these, I had no idea that the guy who started it did it to himself
Wouldn't human-animal conversion rates for psychotropics be more accurate if we used brain weight instead of body weight? Body size doesn't always determine brain size.
You'd probably have to calibrate for both since if a subject has a relatively high brain:body volume ratio, the substance is more likely to end up highly concentrated in brain tissue.
Liver and kidney function for the animal will have a huge effect too. In humans of exact same body size and structure, if liver or kidney function is better or worse it will have a massive effect. Liver because it metabolizes the drug and kidneys because they determine how quickly it is filtered out.
Both great points.
With modern technology, with retinal movements use to interface with computers, we could probably get a great deal of info from a decapitated head that would allow possible communication of complex thoughts through said interface.
There is absolutely no possible way that a decapitated head called out in any way shape or form. Even if the cut were low enough on the neck to include the larynx, there are no lungs or other means to push air through and produce sound. It is physically impossible.
The two headed dog experiment was definitely Frankensteinian, (new word?). Perhaps the ultimate aim was to transplant a healthy head from an unhealthy body to extend the life of an important individual like a scientist for example. Imagine if they could have transplanted Stephen Hawking's head onto a new body? And although he lived a long time could he have achieved even more than he did? He might not be the best example. One better example might be William Clifford, a brilliant mathematician who proposed that matter results from curvature in space and that gravity is a natural consequence of this curvature - one of the key concepts in Albert Einstein’s general theory of relativity. He died at the age of 33 of tuberculosis. What might he have done if he had lived?
LSD doses are measured in micrograms(µg/mcg), not milligrams(mg). .2 mg/kg would mean 16000µg for a person weighing 80kg or about 100 times what most people would consume to trip on it(tabs are commonly around 100-300µg).
The two-headed dog sounds much like something from Michail Bulgakovs 'A Dog's Heart' novel.
I remember seeing a chicken head after decapitation. The eyes blinked a few times. It was kind of gruesome.
Weird semantic observation that I liked. "Can the ends validate the means" vs "Can the ends justify the means"
That was the politest way to say "I told you so" nearly 30 years later.
Not gonna lie some scientists in this video deserve to be flayed. To understand the science behind it, of course.
There a lot of that shit going on today. Not letting something blink or sleep can only be done for some many fucking decades. We're still doing it to animals though. For science... or some fucking lie.
I second this
I'm honestly shocked that Cornish's work didn't attract the attention of a certain mustached man and his posse
They also sent a dog to space without any return plans... That's just as cruel.
>Grafts 2 dogs together
>People start complaining that its unethical
Demikov:🗿
Experiments don't fail. They always give you an answer.
RIP tusko
He died how he lived
High
Just to note:
A dose of 0.2 mg - 0.3 mg per KG of bodyweight for LSD would be an astronomical dose for a human.
The standard dose range would be roughly 0.075 mg/75ug (micrograms) - 0.4mg/400ug IN TOTAL. There are obviously some outliers depending on experience etc.
A person weighing 70kg taking 0.2mg per kg would dose at 14,000ug.
That dose would result in almost certain severe psychosis, probably PTSD, HPPD, a very long hospital stay for 99.5% of people for sure and you would never ever come back the same person.
I dread to think what that poor elephant went through 😣
A dose of 297,000ug is absolutely insane overkill, even for an animal that size.
I'm a person that believes that the ends do justify the means. It's a simple balance equation of if you did more good than harm then the event is good
However, that does not mean that you can be reckless. An attempt to mitigate harm as much as possible does need to be made
Also, such a stance does not forgive the people carrying out these tasks unless they were wholeheartedly trying to benefit the greater good
# 3: Isn't the conundrum for this similar to the conundrum of using the scientific/medical info gleaned during WWII by the Nazis ?
Simon,
After seeing the thumbnail for this episode, no way am I going to watch this!
I think the ends can justify the means, the trouble is you can't use that as justification because you have no idea that the ends will justify the means. It's more, in retrospect, we can argue the means had some justifications.
That is exactly why the end never justifies the means. You just did it and hoped that the result would be worth it. That isn't acting ethically, it's chance. You always have to make sure that even if all fails, you did right by people.
I'd love to sit down for tea with Simon and the writers and talk about all of these random topics.
Cornish's Lazarus experiments sound eerily like the plot of Pet Sematary. I wonder if King was aware of them.
You know it’s odd that all these doctors are similar characteristics to how they say you recognize psychopaths. Cruelty to animals.
“Unfortunately, despite their elephants, Tusko did not recover” amazing slip of the tongue there Fact Boi
Today we call it “scientific experiment”, back then it was “I eat this plant, if I die don’t eat it, if I survive we keep eating it”
The two-headed dog experiment is one of the most cruel experiments I've ever heard of. Imagine being anaesthetized and then just waking up with the lower half of your body gone, and you're sewn to another person like something out of a fucking horror movie. And those dogs couldn't understand what was going on.
I'm glad that we have so much knowledge today, but some of these "scientists" were literally just psychopaths using "research" as an excuse to do insane shit
Imagine being able to heal para and quadriplegics by transplanting their head onto another body.
Where do you start research?
@@DawidUliczny-ro7eo there's no scenario in which you'd need to keep both heads alive at the same time
The canine centipede?
As much as I agree. Things like this can also lead to learning and massive breakthroughs. It's the fine line between ethical and moral standards and what humans are willing to do to discover a species changing medicine like antibiotics or something or fixing paralyzed people
I watched the actual footage from the two headed dog and the back from the dead dog.... That is most uncomfortable I've been in a long time, seeing the clips again here a few years later just ugh. It's unsettling to say the least. They take a close second after viewing the old footage of a human with rabies..
Anyone else notice the slip of the tongue? "Unfortunately, despite their elephants, tusko did not recover" 😂😂
2:20 that's wrong. The dose for humans is not 200-300 micrograms per kg, it's 200-300 micrograms TOTAL. Hopefully nobody ever uses this video as a reference for how much lsd to take, as ingesting 0.3mg per kg of bodyweight would be a colossal overdose. Lsd has detectable effects with as low as 10-20 micrograms in humans (total dose, not per kg).
For a brief period, at least, Tusko became Ganesh. Lol
Video pauses on the very first frame:
Me: "Don't look at me with those eyes, Simon." *Blushes*
Amazing the outcry when legitimate scientists, yes I love dogs and have 4 of them btw, do work that moves a field forward exponentially with their experiments and have helped save maybe hundreds of thousands if not millions of lives, yet most can't get past the those poor animals issue. And while I do agree that frivolous and needles experiments are terrible , like spraying perfumes in animals eyes, etc. But to move ourselves forward some martyrs have to be sacrificed. I've also noticed no one seems to care this much when the actual test subjects are humans. Unit 731 and Joseph mengela with the nazis are just 2 examples. Humanity is amazing... we love dogs and hate other humans... I'm sure there's some great irony in that statement. Simon you're the best and keep up the great work...
YOU KNOW WHAT I'M SAYING PETER!
No one seems to care as much? What?! What Mengele did was absolutely appalling!!!
@@smooshiebear80 of course it was appalling... and he lived out the rest of his days on a beach in south America, because the world cared so much...
@@elijahgiter9559 Not the entire world, just some people. For them, it’s easier to commit atrocities when you don’t view the victims as human. They probably had a higher regard for dogs.
"ethics" did nothing but hold back progress, like in most cases. Millions of loves could have been saved thanks to technologies from this reserch
What a great episode 😮
Tusko must have gone out tripping absolute balls though.
When we were be trained on blood chokes for hand to hand combat in the Marines, we were taught that when done correctly, unconsciousness is achieved in 3-5 seconds. Clinical death in 8-13.
how close are we to disembodied head in a jar?
*Yes just like "DIGBY" the world's biggest dog 😊👍*
"Ed-ward. You promised you'd play with me."
I don't like it when people speak of animal rights. The concept of rights is unique to humans. In nature there is no right to anything. If the stronger animal wants to kill you you can't say you have any rights or make demands. Kill or be killed, eat and be eaten.
Very good point. 👍🏼
acid's measured in micrograms (1mcg=.001mg). hallucinations can start w/ just 40-75mcg (.04-.075mg). based on the calculation of .2-.3mcg/kg body weight, w/ a body weight of 175lbs, that measures out to 35-42mcg which matches up with the minimum hallucinatory threshold.
based on your low dose calculation of ".2-.3mg" a 175lb person would be taking 35mg=35000mcg, meaning a maximum perceptual saturation dose that will be extended in duration as your body has to metabolize so much more. in average cases, 1.5-2mg (1500-2000mcg) doses last 12 hours, and every .01mg (100mcg) extends time by .5-1 hour.
alternatively maybe your editor meant to write .2-3mg total as a full hallucinatory dose, as that is only slightly higher than a typical recreational dose...
either way, viewers are fixin' to try your calculation and become personal friends w/ the void lmao
0:00: 🐘 A study in 1962 attempted to replicate the aggressive behavior of elephants during mating season by administering a high dosage of LSD to an Indian elephant named Tusco, but tragically Tusco overdosed and died.
3:19: 💉 The experiments discussed involve high doses of LSD and the creation of two-headed dogs through organ transplantation, highlighting the dangers of reckless drug administration and the ethical implications of scientific exploration.
6:36: 🐶 The experiments of Dr. Demikov and Dr. Cornish involving dogs were ethically controversial but contributed to scientific progress in organ transplantation and resuscitation.
10:21: 🔬 The article discusses the controversial scientific experiments conducted by Cornish and Burrow on animals and humans, respectively, to explore the persistence of consciousness after death.
13:10: 🧠 The experiment on post-decapitation consciousness by Burrow remains controversial, with no concrete answer on whether the decapitated head retains consciousness or sentience.
16:14: 💡 Werner Forsman's pioneering experiment of inserting a catheter into his own vein laid the foundation for cardiac catheterization.
Recap by Tammy AI
I know this is a little late but I just wanted to point out the error in wording in the beginning of the video. You said that they were psychotropic drugs but the term for it, used in anything but a microdose, is actually a psychedelic drug. Tropic is brain enhancing, psychedelic induces hallucinations
Does anyone else find it weird seeing Simons legs? Or knees
with half the video dedicated to the scientific torture of dogs, i was quite surprised to not see Ivan Pavlov on the list here.
Yeah I started with a cheeky half a fragile, didn't feel anything, had another cheeky half, still nothing so I took a whole one, still nothing, then I stood up and started walking, I felt my self be thrown backwards out of my body and I thought I died, I could see myself walking along like I was floating behind myself and the rest of the evening just got more and more interesting, only problem was I started my my first ever job the next morning, I made it in but that was one long day.
Simons moral high ground is exhausting
Those two headed dog videos are a great test for psycopathy...
From the Tusko experiment, it seems body weight is not the thing to measure against, rather an estimate of the weight of the nervous system might be better.
A common dose of LSD would be 3 micrograms a kilogram, not .2-.3 (200-300 micrograms) milligrams a kilogram, although an active dose of LSD can be as low as 1 microgram a kilogram.
In other words, 70 micrograms of LSD would produce noticeable effects in a 70 kg man.
In the town I grew up in, there was a Lavoisier boulevard. And the last name Languille means "the eel" in english and is pronounced "Lhanguiye (L-han(as the sound we make when we want someone to repeat but the H is silent: HAN?)-gui(as in the word "GUIlt)YE(as in YEah). Lhanguiye
You said .02-.03 but the graphic showed .2-.3
Most of these are horrifying but you at least ended with a more positive experiment
How would the head have called out to the observing scientist? Assuming something went wonky and the cut was far enough down to include the laynx somehow there'd still be no way to push air through it to make sounds.
The head was supposed to communicate by blinking, not talking.
this just shows us how far people are willing to go in the name of science im not saying thats bad or good im just stating the obvious ...
10:00 ethics stoped this?
Huh? That's like saying how far we are willing to go in the name of religion, or love, or just plian old sex (and how much farther for kinky sex?) --- We'll DO ANYTHING. We'll go ANYWHERE. We're so fucking bored. All we need is time.
No more horrible animal torture videos PLEASE! Simon. Thanks Mate.
I'm surprised the attempts at a talking dolphin experiments weren't covered in this video
“How much acid, Dr West?”
“I don’t know, just fuck him up fam”
CIA: “SIGN HIM UP”
He also created 20 no headed dogs
7:18 a complex fusion of dogs as well.
I do love to hear the unethical and macabre experiments in a morbid sense but I can't imagine anything like these experiments happening in modern times. It feels more like a circus of the past.
'despite the elephants' 😂 never change simon.
7:18. Seems to be a complex fusion of dogs as well.
Circa 1990, at least, there was a Museum of Surgery in Moscow that contained a preserved specimen of one (or is it two?) of Demikhov's dogs, Seriously disconcerting.
i despise the youtube algorithm, i with it would go away
Every experiment that "fails" contributes to our knowledge as much as the ones that succeed. Knowing what *isn't* the correct answer helps narrow the possibilities of what the correct solution is.
I'm certain all sociopaths rationalise those "failed" (code word for killing or permanently disabling) experiments on unwilling participants have the same insight that you have. That is the benefits they personally gained from these results were more than the price other people or animals paid.
@@MrStringybark Lol
Well after those dog stories I’m going to need some time with my doogs to clear away the dark stain that the stories left.
I put off watching this for a week because I was *obsessed* with Demikhov's experiments when I was younger, and I can't handle hearing misinformation about them without being able to properly respond. But this was done fine!
Like I said, I was super interested in his experiments with the dogs and working with tissue rejection, and now that I'm older I have mixed feelings. I'm actually an organ transplant recipient, so without his early work I might not have lived past 25.
But the deeper implications of our ability to control life and death with such archaic techniques fascinated me as much as his abuse of dogs horrified me (dogs have been my raison d'etre since childhood).
So yeah, on the one hand, absolutely monstrous experiments and vivisections. On the other, insanely useful results that I'd be dead without. If I had been the only person saved by a transplant I'd be devastated by the pointless waste of canine life, but as it is, I can't at all give an opinion.
The Lazarus Dogs, on the other hand, had no place being abused and thrown away like that. Every tiny bit of information gleaned from that series of "experiments" (AKA pointless slaughter of animals) could have been learned in other ways.
The acceptance speech should have been "Bwaahhahahah!!!! THEY SAID IT COULDN'T BE DONE!!!!" 😝😝😝
@3:00 "unfortunately, despite their elephants, Tusko did not recover..." Simon made me snort with laughter at the death of an elephant. Now I feel bad.
Lol, the street I live on, a main thoroughfare, is abbreviated LSD. So when I or someone else texts or posts , “I was on LSD, and this jerk cut me off,” people sometimes react; “what?!” “No, the street.” It’s much more amusing in the moment - “ya had to be there.”
"I was on LSD and this assh*le pulled out in front of me"
"I was on LSD and some f*** kept riding my ass"
"I was on LSD and almost saw this massive pileup"
Nice
i have conflicting feelings that some of these experiments generated valuable enough knowledge to save the lives of generations after
2:20 0.2-0.3 milligrams per kg is incorrect. From what google tells me, a usual dose is around 100 micrograms (not per kg). 100 micrograms is 0.1 milligrams. Later it's stated they started big by giving the elephant 0.1 milligrams per kg. If that was starting big, the original figure is obviously wrong.
Also, the overdose potential for humans is pretty low. According to Wikipedia there have been no known overdosed deaths, and in 2015 a 49 year old woman survived a dose of 55 milligrams without any ill effects. About 550 times the normal dose.
There was also a case of 8 individual who took exceedingly high doses of LSD thinking it was cocaine. They had a plasma level of 1000-7000 micrograms per 100ml.. considering a person has around 5l liters of blood, and plasma is 55%, that's about 27.5-192 milligrams.
The only thing this teaches me is we don't deserve dogs or any other pets in general
I've only ever chopped off the heads of chooks prior to preparing them for dinner but I have never seen a chook not blink. Not only did they blink but they seemed to be every bit aware as before their decapitation. I find it logical to believe that a person can still be aware for an unknown time after decapitation. How long would depend upon blood loss and how much oxygen was in their blood and therefore in the brain cells at that time. To state consciousness cannot continue flies in the face of reality and anecdotal evidence of those who have seen this phenomenon with their own eyes.