Increase Your Mitochondria, Your Body Will Thank You | The Acid Drop

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  • เผยแพร่เมื่อ 7 มิ.ย. 2024
  • As it turns out, mitochondria are essential for cellular function, and virtually every cell in the human body. We just learned about some exciting research whereby a dietary intervention can in fact dramatically increase the number of mitochondria in immune cells. That is certainly a plus. There’s some great information here.
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ความคิดเห็น • 423

  • @marconi3142
    @marconi3142 8 หลายเดือนก่อน +37

    A low sodium diet is only for people that are mainly sedentary. For those of us who exercise and stay active, a higher sodium (sea salt) diet is much more preferred.

    • @DruidzTV
      @DruidzTV 2 หลายเดือนก่อน +1

      same applies for low carb diets

    • @AlanNguyenMD
      @AlanNguyenMD 2 หลายเดือนก่อน +4

      you need potassium to balance sodium

    • @nosretep1960
      @nosretep1960 21 วันที่ผ่านมา +1

      ​@@AlanNguyenMDabsolutely! I get @4-5g daily just in my homemade electrolyte drink as potassium nitrate, hence my nitric oxide also tests high. Life is hard 😅

  • @hoofheartedicemelted296
    @hoofheartedicemelted296 8 หลายเดือนก่อน +49

    Lower Fructose, Lower Sodium + Fasting for Autophagy/Mitophagy. Result = Lower Free Radicals, lower Oxidative Stress, lower Uric Acid. Thanks Dr PerlMutter, you advice is powerful as usual.

    • @sweettaterpie7009
      @sweettaterpie7009 4 หลายเดือนก่อน

      What is best fasting regiment ? Thanks...

  • @brucemattingly6476
    @brucemattingly6476 ปีที่แล้ว +43

    Thanks Dr. Perlmutter..!
    Questions on a few items:
    1) In study low sodium diet defined as below 6g per day. That is 6,000 mg a day which is huge number..! If we are avoiding processed foods, eating whole food, and maybe only adding modest amount of let's say Himalayan pink salt to our diet, most of us will be way below 6,000 mg of sodium daily..!
    2) Study defined low fructose as below 20 g of fructose daily. It would have been helpful if you would put that into perspective. Quick study on high fructose foods identifies banana with about 6 g of fructose. Of course we should minimize fruit juices, processed foods containing high fructose corn syrup, etc., but my understanding is 2-3 pieces of whole fruit a day should keep us way below 20 g fructose daily, as whole fruit often contains fiber, other nutrients, that can act as buffer to modulate blood sugar to keep in acceptable range.
    The scope of this video may not have included the above two items, but I found myself wanting while watching video due to no context provided on practical ways to adjust our eating habits to stay below 6,000 mg sodium and 20 g fructose daily.
    Also, it would have been great to give viewers some dot points on other topics to improve mitochondrial function, and mitochondrial production, so viewers could do additional research on supporting optimal mitochondrial function as we age.
    Thanks again..!

    • @josephrz6230
      @josephrz6230 10 หลายเดือนก่อน +4

      I think those of us that eat only whole nutrient dense foods can use Real Redmond salt on our food freely and still be way under 6g of sodium per day.

    • @koreyb
      @koreyb 9 หลายเดือนก่อน +1

      No.

    • @bobcooter
      @bobcooter 9 หลายเดือนก่อน

      Very helpful. Any ideas on how to calculate how much extra a person who is sweating a lot under the sun in a manual labour job along with heavy resistance training in the evenings might need? Obviously impossible to tell without exact details, just interested to know what you think.

    • @josephrz6230
      @josephrz6230 9 หลายเดือนก่อน +1

      @@bobcooterTry 1 tsp and see how it feels. You may need more than that at times.

    • @irenewarhol1241
      @irenewarhol1241 5 วันที่ผ่านมา

      Methylene Blue helps your mitochondria, research it.

  • @bienstar4349
    @bienstar4349 ปีที่แล้ว +46

    Mitochondria is the powerhouse of the cell…

    • @johnbemery7922
      @johnbemery7922 ปีที่แล้ว +11

      it's not a mitochondria video until it uses that phrase!

    • @slobodanpavlovic3184
      @slobodanpavlovic3184 8 หลายเดือนก่อน

      *powerstation

    • @charles2521
      @charles2521 2 หลายเดือนก่อน

      Mitochondria are a microscopic life form that resides within all living cells. And we are symbionts with them. Life forms living together for mutual advantage. Without the mitochondria, life could not exist and we would have no knowledge of the Force. They continually speak to us telling us the will of the Force.

    • @fairenough7984
      @fairenough7984 16 วันที่ผ่านมา +2

      The mighty mitochondria 😁

  • @rythmicwarrior
    @rythmicwarrior ปีที่แล้ว +26

    My takeaway is; 1. We have evolved to fatten up in the fall and hibernate through the winter. 2. The deeper we dig into things, the more questions we come up with.

    • @booswalia
      @booswalia 8 หลายเดือนก่อน +3

      Something else people forget is that the foods that grows locally is enough to sustain and create health. Otherwise we wouldn't be here. You don't need avocados if they don't grow where you are. Find another source of good fat. The further north you go the more you need to choose meat.

    • @Lykapodium
      @Lykapodium 3 หลายเดือนก่อน +1

      Not sure that applies universally. Maybe for people that live in cold climates... People who live in the subtropics and to the equator can be outside year round working, exercising, etc... I think cold weather people get lazy in the fall and realize they need to look good for the beach or pool in the early spring. It's psychological for the cold weather folks

  • @mustseevideos7777
    @mustseevideos7777 8 หลายเดือนก่อน +1

    You are a true life saver Dr. Pearlmutter. I am always blown away by your depth of knowledge and how simply you explain it to us. May you be blessed in all things good.

  • @franzbuchel7295
    @franzbuchel7295 ปีที่แล้ว +41

    Great presentation, Dr.Perlmutter! Please present more factors/studies how to improve mitochondrial function-
    would be highly appreciated.

    • @cain6981
      @cain6981 9 หลายเดือนก่อน +3

      Red light therapy, sauna exposure around 180 degrees Fahrenheit, regular exercise, and doing cold therapy like ice baths a few times a week. Low sodium diet goes against most Dr's these days

    • @hd-be7di
      @hd-be7di 8 หลายเดือนก่อน

      @@cain6981 Add Vitamin D3, the main catalyst in cell energy production

  • @margaretmm1627
    @margaretmm1627 ปีที่แล้ว +171

    This study is incredibly interesting re fructose but I can’t see it tells us anything about sodium. The comparison was low sodium vs low sodium with high fructose. Unless you also compare with medium and/or high sodium combined with low or high fructose only the data on fructose is meaningful.

    • @Celtokee
      @Celtokee ปีที่แล้ว +19

      That was to be my comment exactly. Thank you!

    • @bryantcofty2709
      @bryantcofty2709 ปีที่แล้ว +15

      Yes, that seems glaringly obvious. Surely there's an explanation (by the researchers) regarding this point. I can't imagine what it would be though. Then again, there's a PLETHORA of poorly designed "bunk" research/studies in publication. I wonder what Peter Attia's, author or co author of a publication of some sort called "studying studies", opinion would be should he take an in depth look at it?

    • @medini2
      @medini2 ปีที่แล้ว +5

      Sodium is an enzyme inhibitor.

    • @gypsypath1
      @gypsypath1 ปีที่แล้ว +23

      @@bryantcofty2709 At this point, I’m cynical enough to think it had to do with funding based on the “low salt = good” message.

    • @LoveSumsItUp
      @LoveSumsItUp ปีที่แล้ว +37

      We are electric. Need sea salt, Need real salt.

  • @davidchang8468
    @davidchang8468 ปีที่แล้ว +14

    Thank you very much doctor.🙏 This is the clearest and most useful clip on "polyol pathway" mechanism. Such understanding provides for important direction for elimination diets. It was my good health fortune to have listened in.

    • @patriciamasterson4721
      @patriciamasterson4721 ปีที่แล้ว +3

      Thank you Dr. Perlmutter. At my age 80 this. Helps to better understand why my mitochondrial function isn't balanced enough to create new muscle. And healthier skin
      Etc. I'll just keep up with my biodynamic agriculture foods and clean diet.

  • @cybernurse2020
    @cybernurse2020 ปีที่แล้ว +11

    Excellent and interesting presentation! Thanks for the many ways you help all of us learn. You're a great teacher. 🙏

  • @X-zk9vm
    @X-zk9vm ปีที่แล้ว +31

    Most nutrition for mitochondria is NIR .near infrared from sunlight especially morning and evening when the uv index is low ,below 3

    • @winglau7713
      @winglau7713 9 หลายเดือนก่อน +5

      hi! there, I am wondering if you care to provide a reliable source for your statement? thx.

    • @MEF7
      @MEF7 9 หลายเดือนก่อน +2

      Can you explain please.

    • @jeffreyadams648
      @jeffreyadams648 3 หลายเดือนก่อน +1

      Doing just that. It’s helping.

  • @Myself500
    @Myself500 ปีที่แล้ว +7

    Wow! I heard that salt could cause oxidative stress but didn't understand why and it gives the answer, thanks for it.

  • @BluesDoctor
    @BluesDoctor ปีที่แล้ว +7

    To several who noted, yes there have been follow-ups showing NaCl is the bigger player in this. Just remember if you cut out or cut way back on Iodized Salt, you must supplement with Iodine....

  • @domalltobello2759
    @domalltobello2759 26 วันที่ผ่านมา +1

    David Perlmutter should win a Nobel Prize. Incredible video.

  • @bonnieromick9397
    @bonnieromick9397 22 วันที่ผ่านมา

    Please continue with U tubes. I'm a naturopathic person with HSV and I research mitochondrial support and thymus regeneration. I will watch mito u tubes more than once as I am getting very familiar with specific medical terms. Appreciate you Bonnie

  • @lsporter88
    @lsporter88 9 หลายเดือนก่อน +1

    Thank you Doctor Perlmutter. Excellent presentation.

  • @tacmason
    @tacmason ปีที่แล้ว +1

    I am retired, and I don't buy very many new books now-a-days !, But I bought 'Drop Acid" yesterday ! (It cost $ 31.76 ) Thanks for your sincere efforts to help us all !

    • @angellight9500
      @angellight9500 2 หลายเดือนก่อน +1

      try your library...they have great stuff

  • @higherresolution4490
    @higherresolution4490 ปีที่แล้ว +30

    Central nervous system neurons have a lot more than 1,000 mitochondria! The range is between 2,000 and 2,500. Cardiomyocytes also contain about that same number. Highly physiologically active cells found in the kidneys, liver and spleen generally number over 1,000 mitochondria.
    Although it's been a while, the director of the mitochondrial lab I worked in said that the current (2010) estimate of mitochondria in the ovum is 250,000. However there was speculation that the number may be as high as 1 million.
    Note that mitochondria compose 10% of human body weight. The number of mitochondria in the human body is roughly 10^17.

    • @RAY-bg2po
      @RAY-bg2po 11 หลายเดือนก่อน +2

      Great info, thanks..

    • @kyhxx
      @kyhxx 8 หลายเดือนก่อน

      . sep.t3- no brnach*

    • @tizzlekizzle
      @tizzlekizzle หลายเดือนก่อน +1

      Wow, thats a neat fact.

  • @Thomas-pq4ys
    @Thomas-pq4ys ปีที่แล้ว +2

    Would you PLEASE post the link to this study in the lowbar? Thanks!

  • @michaeltrumper
    @michaeltrumper ปีที่แล้ว +16

    High salt and fructose intake are a marker for a diet high in processed food. However seems to me that fructose is the driver not the salt. See Richard Johnsons' research on fructose.

    • @szymonbaranowski8184
      @szymonbaranowski8184 ปีที่แล้ว +4

      High salt does the same as fructose, also glutamine in diet. But ofc too low salt is very bad or worse. Salt is also a driver for sure also creates uric acid reaction.
      But some salt before exercise is very healthy for heart providing more blood volume and so less need for oxygen for heart in hard situation or while digesting and moving with high blood requirement.

  • @CarbageMan
    @CarbageMan ปีที่แล้ว +73

    I read your book, "Drop Acid," and I'm skeptical of subclinical hyperuricemia in the absence of excessive carbohydrates. Are you sure the "independent" risk factors of UA are really independent at the subclinical level? I suspect there are cofactors that are not accounted for, as carnivores would all be suffering the consequences, and there have been plenty over the ages. I think fructose (or excessive other carbohydrates), for example-even in high fiber foods-is a likely cofactor, for sodium too. I'm sensing a potential plant-based bias and/or dependence on low-quality epidemiological studies.
    PS: My suspicion is that people who strictly control carbohydrates may not need to worry about subclinical hyperuricemia, and that in that context, sodium is also not an issue. I can't prove it, but I'd like you to tell me if you know why that's wrong-because we're both after the truth.

    • @LTPottenger
      @LTPottenger 11 หลายเดือนก่อน +14

      You will definitely have high uric acid levels if you eat only meat, but that does not really mean anything in and of itself. It's not the uric acid itself causing issues, though it seems that way. It is your liver (not kidneys) being metabolically deranged that makes your kidneys unable to deacidify the blood enough to keep uric acid crystals from forming. Make sense? Probably not, but it is not a simple subject.

    • @curiousbystander9193
      @curiousbystander9193 9 หลายเดือนก่อน +1

      @@LTPottenger thoughtful, thanks........let's hope the doc here deals with the subject of upper gi tract glycan binding lectins and their relationship with acidic food consumption......

  • @rizwanwaseem207
    @rizwanwaseem207 ปีที่แล้ว

    Lovely info. Can you please mention the test name for mitochondrial density. Thanks.

  • @STOPPOLICECORRUPTION
    @STOPPOLICECORRUPTION ปีที่แล้ว +24

    Didn't know there was a test for Mitochondrial density, appreciate the info.

    • @cybernurse2020
      @cybernurse2020 ปีที่แล้ว +4

      Agree. How or what do you order on a regular lab requisition?

    • @williamkayaian7268
      @williamkayaian7268 ปีที่แล้ว +2

      Hello , right ?

    • @james575730
      @james575730 ปีที่แล้ว +2

      the company viome tests mitochondria also

    • @viragkaroly2949
      @viragkaroly2949 9 หลายเดือนก่อน +1

      They will test you anything, if you pay enough. They will also make you believe it is important.

  • @johnross3295
    @johnross3295 ปีที่แล้ว +5

    Thank you Doctor! Liked and Subscribed. Just started reading your Grain Brain book... fascinating! Keep up the great work!

  • @kulturfreund6631
    @kulturfreund6631 ปีที่แล้ว +22

    Many thanks for the information.
    From another video I was told that the intake of sodium (preferably in the form of sea salt or Himalayan salt, as these are rich in many other minerals) should be counterbalanced by the right amount of potassium (leafy salad, avocados, bananas etc.) and that half a teaspoon per day, especially when transpiration is increased, is a good thing to add.

    • @alexforce9
      @alexforce9 ปีที่แล้ว +8

      you need potassium and magnesium regardless of how much sodium you consume. Its just best those 3 to be in synergy for optimal cell energy, hydration and ofc your blood pressure. BTW - potatoes are one of the best potassium sources. They can feed you, be tasty as heck and are low calories if you are looking for that hehe. Carrots also have plenty of potassium. And fresh carrot juice is just heaven.

    • @danielmason8574
      @danielmason8574 ปีที่แล้ว

      But is potassium chloride in anyway heat sensitive/damaged?

    • @veniqer
      @veniqer ปีที่แล้ว +1

      Animal products contain potassium.

    • @michelangelobuonarroti916
      @michelangelobuonarroti916 11 หลายเดือนก่อน

      @@danielmason8574 No.

    • @michelangelobuonarroti916
      @michelangelobuonarroti916 11 หลายเดือนก่อน +1

      @@veniqer They do, but the most potassium-rich food sources are fruits and vegetables.

  • @kursk124
    @kursk124 9 หลายเดือนก่อน

    Excellent video. Thank you

  • @williamhoffer9277
    @williamhoffer9277 9 หลายเดือนก่อน

    Great presentation!

  • @user-hx8th2dd5z
    @user-hx8th2dd5z ปีที่แล้ว +18

    So, low sodium = no significant change. Low sodium/ low fructose = significant positive change. Why didn't the study include the effect of low fructose in isolation? Also, am curious on the effects this would have on subjects not overweight-- of normal healthy weight?

    • @szymonbaranowski8184
      @szymonbaranowski8184 ปีที่แล้ว

      High sodium is the same as fructose. Literally spikes uric acid the same way

    • @Petunia-Greene
      @Petunia-Greene 8 หลายเดือนก่อน +1

      Yes but combining things can be significantly different than how things work by themselves.
      So really both should be studied by them selves in order to get a more clear picture.
      Salt is highly necessary for many of the functions of the body and you can just cut it out without there being problems.

    • @fourthtunz
      @fourthtunz หลายเดือนก่อน

      I agree would love to have seen the low fructose numbers by themselves

  • @Treasures100
    @Treasures100 หลายเดือนก่อน

    💖 Thank you for a very helpful and informative video..your delivery of info is really great...

  • @kenshey3912
    @kenshey3912 7 หลายเดือนก่อน +3

    I kept walking past your book until late last month. Gout hit my ankle again. Coincidentally our health group, we had others gout confirmed by labs. Found your TH-cam’s
    Now our group of 300 owns 30meters and wow… 75% (roughly) have levels over 7.
    Ordered bulk Quercetin Glycine and Potassium Citrate to start.

  • @richardpenhardt6100
    @richardpenhardt6100 9 หลายเดือนก่อน

    very informative ... well presented

  • @johnmanderson2060
    @johnmanderson2060 ปีที่แล้ว

    Thanks a lot for the advice

  • @jjolla6391
    @jjolla6391 ปีที่แล้ว +9

    why did the study fail to look at just Fructose w/o a change in Salt ? did they cherry-pick it out?

  • @nyalimuir4103
    @nyalimuir4103 ปีที่แล้ว

    Fascinating.
    Thank you

  • @stevelong9328
    @stevelong9328 9 หลายเดือนก่อน +4

    Doctor, in the study they isolated low sodium but not low fructose separately, this is incomplete, I would be interested in a further study.

  • @bobhearn5671
    @bobhearn5671 ปีที่แล้ว +4

    Letting sodium and fructose relative to what? What was the baseline level for the folks who experienced the decreases?

  • @allme7425
    @allme7425 11 วันที่ผ่านมา

    This was powerful info

  • @568843daw
    @568843daw ปีที่แล้ว +11

    Hi doc, great presentation. What blood test reveals the mitochondrial count in the white blood cell?

    • @neuromancer27
      @neuromancer27 8 หลายเดือนก่อน

      I second this question, what is it ?

  • @now747
    @now747 ปีที่แล้ว +8

    So mitochondria dna has increase after 8 weeks of low sodium and fructose diet. Did this translate to the participants feeling to have more energy or had any measured weight loss? Just an increase in mitochondrial dna on it's own doesn't appear to be a useful effect otherwise?

  • @gattonelcielo
    @gattonelcielo ปีที่แล้ว +1

    Thank You! Always interesting and informative.
    What the Swedish news used from this study was the sodium angle...and how much salt there is in processed meals...

    • @higherresolution4490
      @higherresolution4490 ปีที่แล้ว +2

      Knowing what you just said certainly makes this study more understandable. Processed salt in processed foods! Natural salt has 2% trace minerals which is extracted in commercial salt. When harvested from the sea, salt contains 14% moisture.
      Also, sea salt has not been crushed by heavy machinery, thus causing very sharp splinters of crystal which can irritate the endothelia of blood vessels and capillaries, thus causing systemic inflammation.

  • @kevb.1791
    @kevb.1791 ปีที่แล้ว +5

    Interested if instead of lowering sodium you raised potassium and magnesium

  • @herbertvonsauerkrautunterh2513
    @herbertvonsauerkrautunterh2513 ปีที่แล้ว +3

    Very interesting but what about for those that are not obese? I thought we need salt if we work out a lot, do fasting etc... I do keto ore mostly so sugar intake is very l low.

  • @newunderthesun7353
    @newunderthesun7353 9 หลายเดือนก่อน +6

    I love these theories about early man that are pure speculation, but are used to explain current medical theories.
    It's like being a weatherman.

    • @michaelb41
      @michaelb41 9 หลายเดือนก่อน

      Good analogy. Imagine being without the weatherman.

    • @newunderthesun7353
      @newunderthesun7353 9 หลายเดือนก่อน

      @@michaelb41 Knowing what the weather is predicted to be has never changed what I do in any particular day. Sure, some people live under threat of tornados and hurricanes, but that is what the public safety system is for.
      Likewise, these theories have zero impact on how most people liver their lives.
      I can do without them both.

    • @aleksandrazimpel8097
      @aleksandrazimpel8097 3 วันที่ผ่านมา

      ❤😂

  • @CarbageMan
    @CarbageMan ปีที่แล้ว +5

    Did they not control for only low-fructose? I saw only the comparison between low-sodium and low-sodium, low-fructose.

  • @jimvellios1426
    @jimvellios1426 8 หลายเดือนก่อน

    great info.

  • @MrBDezno
    @MrBDezno ปีที่แล้ว +36

    I'm confused. It seems that many respected doctors & researchers have - in recent times - indicated that salt is of no concern because the body knows how to deal with excess salt/sodium.

    • @michaeltrumper
      @michaeltrumper ปีที่แล้ว +24

      Latest research that I have seen is that people are more likely to have issues with low sodium than high. Salt intake is not an issue if you have good kidney function.

    • @EB321
      @EB321 ปีที่แล้ว +15

      Would have been nice to see another category that were fed just low fructose

    • @szymonbaranowski8184
      @szymonbaranowski8184 ปีที่แล้ว

      @@michaeltrumper high salt intake works exactly the same way as fructose or rather causes uric acid production check out Richard Johnson talking about it deeply

    • @szymonbaranowski8184
      @szymonbaranowski8184 ปีที่แล้ว

      High salt has effects. Body knows how to deal with toxins too should you take toxins? Salt also makes hungry.

    • @michaeltrumper
      @michaeltrumper ปีที่แล้ว +5

      @@szymonbaranowski8184 True, but in context, it is much bigger risk of people having too low salt intake than loo low fructose. Or to put it another way, there is a requirement for endogenous salt, but none for fructose.

  • @bobkoure
    @bobkoure 9 วันที่ผ่านมา

    I've read some studies by Rick Johnson. The polyol reaction seems to be key to uric acid levels which in turn prompts conversion of glucose to fructose (and triggering the 'uricase mutation'). His take on it (interview with Dr. Peter Attia) is that it's relative sodium levels - so dehydration can do this as well. His take on it was (paraphrasing) "if you're going to eat something salty, drink liquids first).
    It's an interesting area. I hadn't made the connection with mitogenesis and mitophagy but how else would an organism reduce energy consumption? Subscribed, BTW.

  • @avecrux333
    @avecrux333 7 หลายเดือนก่อน +2

    QUESTION: How do we know which is the cart and which is the horse? Do people with low mitochondrial function feel energy-starved and need to eat carbs for energy, so that's how they gain weight? Rather than mitochondrial function declining as a result of weight gain?

  • @OnePercentersDotNet
    @OnePercentersDotNet 9 หลายเดือนก่อน +2

    Why do scientists so often mix multiple variables into studies? Did I miss something? Where is the study of low sodium on mitochondria and low fructose on mitochondria? What sense does it make to introduce another variable? Apparently sodium had minimal effect, but fructose was a significant difference.

    • @nevinkuser9892
      @nevinkuser9892 6 วันที่ผ่านมา +1

      That's the honest truth. The only thing that likely has any effect is sugar. Salt is negligent.

  • @debjordan4399
    @debjordan4399 9 หลายเดือนก่อน +3

    I would have found additional interest in seeing the results of a group that was only low fructose.

  • @pookiroo
    @pookiroo 15 วันที่ผ่านมา

    Agape 💙 .Dr. David. Ty 4 telling me the truth. I'm on it.

  • @mikeallen6784
    @mikeallen6784 ปีที่แล้ว

    How long should it take to drop Uric Acid, say, to 6, from 7, if following the protocol described in your book?

  • @YTCh424
    @YTCh424 10 หลายเดือนก่อน +1

    You mention a simple blood draw test to measure mitrocondira in the white blood cells. What is the name of this test? Thank you

  • @mikecain6947
    @mikecain6947 ปีที่แล้ว +1

    Do we know what happened to the energy levels, the blood pressure or cognitive function of the study subjects?

  • @user-hr3sg7rf8w
    @user-hr3sg7rf8w 9 หลายเดือนก่อน +5

    @DavidPerlmutterMD Would you consider doing a video on how to improve mitochondrial efficiency as well ? Thank you for the amazing content that you create to educate us. Much appreciated ! :)

    • @TerriblePerfection
      @TerriblePerfection 9 หลายเดือนก่อน +3

      Get morning sunlight on your retina and skin for improved mitochondrial health, and avoid blue light after sunset.

    • @canucklehead4463
      @canucklehead4463 8 หลายเดือนก่อน +1

      from my undergraduate studies in kinesiology i can tell you that inside the walls of the mitochondria a cascade of numerous chemical reactions takes place to produce the energy molecule atp (adenosine triphosphate). something like 75% of these reactions involve magnesium, so i make sure my magnesium content is topped up.

    • @markhedger6378
      @markhedger6378 6 หลายเดือนก่อน

      ​@@TerriblePerfectionwell said

  • @williamearl1662
    @williamearl1662 ปีที่แล้ว +28

    The study was from 2013, have there been follow ups to confirm the finding? Also why not have seperate studies on fructose and salt? is there a synergy between them?

    • @BluesDoctor
      @BluesDoctor ปีที่แล้ว +7

      To several who noted, yes there have been follow-ups showing NaCl is the bigger player in this. Just remember if you cut out or cut way back on Iodized Salt, you must supplement with Iodine....

    • @powerpopaholic876
      @powerpopaholic876 8 หลายเดือนก่อน

      @@BluesDoctorIF your thyroid wirks

  • @paulafelipe1694
    @paulafelipe1694 ปีที่แล้ว +2

    Question: I see people including children on you tube videos recording extreme carnival rides like on a slingshot or Rollercoaster and often times they scream and even pass out...just wonder what is the impact on the brain..could they be doing irreparable damage?

  • @jintzie1950jth
    @jintzie1950jth 9 หลายเดือนก่อน +1

    what kind of diet is low sodium and low fructose?

  • @Earwaxfire909
    @Earwaxfire909 ปีที่แล้ว +4

    Sodium causes leptin resistance, thus making people hungry. Fructose causes insulin resistance of the liver, thus making toxin processing more difficult. Combinations might synergize to increase advanced glycation end products and inflammatory processes that induce mitochondrial apoptosis in white blood cells?

  • @user-ok7nw3hd4k
    @user-ok7nw3hd4k 9 หลายเดือนก่อน +3

    HIIT has been a clear and simple path to increasing my own mitochondria. This stress forces your mitochondria to multiply. Curious if there is any research data on combing both? I have always taken Fish and Flaxseed oil to keep my blood pressure low and scoop up free radicals etc. I am often thought to be 20 years younger then my actual age.

  • @rizwanwaseem207
    @rizwanwaseem207 6 หลายเดือนก่อน

    It is thought-provoking for me. Please advise.
    - Uric acid is at 7.9.
    - LDL is high.
    - I am 50 years old.
    - I am very active in sports. I cycled 1100 km last month.
    - I have no symptoms of high LDL or uric acid.
    - I have been struggling to lose 5 kg of weight for the past year.
    - I haven't used added sugar for 6 months.
    - I eat mostly boiled vegetables with olive oil once a day.
    - I occasionally eat a small amount of fruit (fructose).
    - I usually don't add salt to my food.
    Please advise on what I should do to lower my uric acid levels, as I can feel that I am not metabolically healthy anymore. My physician is not very helpful.

  • @MrBrianDuga
    @MrBrianDuga 10 หลายเดือนก่อน +1

    What’s the source of sodium they removed? Table salt? I imagine everything in moderation even applies to things like Redmond’s Real Salt. But specifically calling out the source could help determine if iodized table salt is causing oxidative stress.

  • @beckyconstantinides2546
    @beckyconstantinides2546 ปีที่แล้ว

    Thank you

  • @winglau7713
    @winglau7713 9 หลายเดือนก่อน +2

    Thanks for providing the interesting finding. However, what could be the potential links between mitochondria and fructose/salts? It seems to me that conducting a study based on already obese individuals don’t make a lot of sense since they need to reduce daily nutrients intake anyway.

    • @Alice_Walker
      @Alice_Walker 9 หลายเดือนก่อน

      If you do a little digging on pubmed you'll find this study was called into question with the sample size too small and the variance of results too large to draw any meaningful conclusions.

  • @jimking6484
    @jimking6484 ปีที่แล้ว +1

    If my blood test shows low sodium is that the same as reaffirming a low sodium diet? Sodium is a necessary mineral for electrolytes assisting in the electrical aspect of exercise and the heart.

  • @enkidu001
    @enkidu001 ปีที่แล้ว

    thank you

  • @Project_9_subfolder_7
    @Project_9_subfolder_7 ปีที่แล้ว +3

    If I read it correctly at 5:20, low sodium was defined as less than 6,000 mg, which is still a lot

  • @michaelberman3648
    @michaelberman3648 9 หลายเดือนก่อน +2

    In addition to many other supplements, I am taking 20 mg per day of pyrroloquinoline quinone or PQQ. Are there good substantive studies done on this compound with respect to mitochondrial function and mitochondrial genesis?

    • @Meow-ds7pr
      @Meow-ds7pr 8 หลายเดือนก่อน

      Pqq works but use it in conjuction with exercise or just walking do ur daily steps

  • @jonahbert111
    @jonahbert111 ปีที่แล้ว +2

    So, how does one go on a low sodium (salt) diet and not threaten the essential level of hydrochloric acid in the stomach? I would suggest using chloride forms of minerals such as magnesium chloride, calcium chloride, zinc Cl, etc where ever possible.

  • @Avianthro
    @Avianthro 9 หลายเดือนก่อน

    I'm wondering just how well the white blood cell mitochondrial density correlates-serves as a proxy for muscle tissues (?). Seeing a 70-fold increase in mitochondrial density sounds like it would mean a fantastic rise in potential muscle cell performance. I know there would still be other muscle performance limiting factors, but at least mitochondrial density should no longer be one.

  • @emj3677
    @emj3677 ปีที่แล้ว +3

    What happens to the mitochondria if the person has a neutropenic fever due to chemotherapy? I had breast cancer and after my first dose of chemo, I got neutrpenic fever after my first dose of chemo. I was told that my neutrophils were 0.5 and normal was 13. I recovered, but I was wondering if that is why I had 'brain fog' afterwords the chemotherapy and radiation. That was 10 years ago. I am currently eating a low sodium and most of all, low sugar (carb) diet. I got off of sugar using monk fruit and now I am trying to eat less real fruit with the exception of a few, like kiwis. I am also taking vitamins such as MNM and trans reseratrol. I am noticing that my I have been retaining information better and memory has improved. Please tell me what you think about this.

    • @michaelb41
      @michaelb41 9 หลายเดือนก่อน

      Dr. Peter Attia address many health issues that you would be interested in. First in my mind is becoming bullet proof to illnesses. Largely that is due to exercise. Attia has many videos on TH-cam and podcast. Best wishes in your journey to wellness and greater health.

  • @geetapillai5525
    @geetapillai5525 5 หลายเดือนก่อน

    I have gone totally off all sugars including fructose since April 2023 . SOmehow though my A1C has come down drastically, for the first time I found that my uric acid levels are elevated to 6.7 . Im completely confused as to what to do what to have how to control this . Could you please advise

  • @hohohomer4566
    @hohohomer4566 ปีที่แล้ว +5

    You didn't mention potassium values !!!

  • @austenlawson5993
    @austenlawson5993 9 หลายเดือนก่อน

    Definitely NOT what I thought when I saw “drop acid”. This is really cool though.

  • @Kwippy
    @Kwippy 9 หลายเดือนก่อน

    My mitochondria are doing good thanks but I am worried about my cytosomes and my Golgi apparatus. People are just not taking care of these organelles and there is so little information available could you please help?

  • @alexforce9
    @alexforce9 ปีที่แล้ว

    This seems to me another good reason to cut off fructose. Just wonder why it toke 8 weeks before we see big changes in mitochondria.

  • @tarikgel
    @tarikgel 9 หลายเดือนก่อน

    Thanks

  • @mrseanpride6449
    @mrseanpride6449 3 หลายเดือนก่อน

    What does drop acid refer to?

  • @sorenskjoldjensen
    @sorenskjoldjensen 8 หลายเดือนก่อน

    What was the sample size, did they placebo-control the overweight subjects and were the overweight participants dieting?

  • @1963charmaine
    @1963charmaine ปีที่แล้ว

    very interesting

  • @moniquelemaire5333
    @moniquelemaire5333 ปีที่แล้ว +1

    Okay, so my ear doctor misdiagnosed me with Meniere's Disease, and literally yelled at me "No Salt!!!". Do for more than a year I ate no or very little salt. The same year, another doctor said I had NAFLD (non alcoholic fatty liver disease). So, I gave up all soda and a big majority of sugars. I lost about 45 pounds. Since 2017, I have been dealing with MECFS. Dr. Sarah Myhill states that we should set just meat and certain veggies and no fruit to get into a paleo-keto diet to help over come MECFS.
    So, what you are saying is, the combination of fructose and salt just might help with promoting the growth of mitochondria???!!!
    What is the test and how can this test be a guide for the individual to increase their mitochondria???
    What I have understood from reading Dr. Myhill and others in the world of MECFS, is that the methylation process produces more mitochondria. The methylation process is based on taking supplements.
    I know you want me to just buy the book,. but it would be nice if you could comment.
    Thank you, Miss Monique 🙂

    • @alexforce9
      @alexforce9 ปีที่แล้ว +3

      Sooo... here is the thing. Sodium is very important for blood pressure. So if you are on low sodium diet - then you MUST check your blood pressure. Coz low blood pressure also leads to all kind of nasty things like fatigue, depression, low energy, feeling cold, brain fog, bad digestion ect. And yeah, ditching fruits and honey and everything with fructose will help your body to get rid of the fat accumulation in the liver. Not sure how eating just meat and some vegies will be good with MECFS - glucose is the favorite energy source of the body. So giving up glucose seems risky specially to someone who have problems with energy already. You probably dont need to look into some special mitochondria treatment yet. But if you want - you can do your best to help your mitochondria - it needs b vtamins, zinc, magnesium, vit c and water.

    • @moniquelemaire5333
      @moniquelemaire5333 9 วันที่ผ่านมา

      ​​@@alexforce9Sorry it has taken me so long to reply back.
      Yes, I have been taking exactly what you recommended: vit. C, D3, magnesium and the others and even though I still need to lose weight, I have been experiencing more energy.... especially since I have been taking B1 for the last week or so. I have also been taking a few iodine drops for my hypothyroidism.
      Thanks again for the help!!
      Miss Monique 🙂🙏🌷💗
      PS. Yes, I am drinking my water everyday 😌.

  • @donross7820
    @donross7820 ปีที่แล้ว

    You are spot on. And anaerobic training can quadruple muscle mitochondrial count.

    • @lyntonblair9016
      @lyntonblair9016 ปีที่แล้ว +1

      I doubt that. Mitochondria must have oxygen to produce energy...

    • @didgeridooblue
      @didgeridooblue 9 หลายเดือนก่อน

      While mitochondria need oxygen to function, is it possible that more mitochondria are produced in an anaerobic environment because of the need for more energy?

    • @benhur2265
      @benhur2265 3 หลายเดือนก่อน

      Both aerobic and anaerobic training good for mitochondria, zone2 training is increasing “the number of mitoc.” while high intenty like zone3-4 making mitochondria larger in size.
      The problem with zone3-4 eventually makes you tired because of that reason zone2 training is much more effective, easy, lowering your hbr but it takes time at least 4 weeks and 3 training for each week. Zone3-4 training you will get results immeadiately,maybe one every 2-3 weeks 1 or 2 speed or interval workout keep you safe.

  • @arthurdolle5257
    @arthurdolle5257 2 หลายเดือนก่อน

    What about the requirement for high sodium intake for low-carb and ketogenic diets

  • @brettrusso6703
    @brettrusso6703 7 หลายเดือนก่อน

    How do I repair mitochondria after ciproflaxen toxicity?

  • @jefforso-richmond4636
    @jefforso-richmond4636 9 หลายเดือนก่อน

    Is salt such a problem. Could you do a book on salt?

  • @robertsmyk4102
    @robertsmyk4102 ปีที่แล้ว

    Maybe there's another explanation! Less fructose means a lower energy in the circulating nutrients and thus a compensation to get the work done with lower energy nutrition is a greater number of mitochondria.

  • @amandatemnykh6815
    @amandatemnykh6815 ปีที่แล้ว

    I don't understand why our ancestors's bodies would've perceived the intake of fructose as a sign food was scarce and mitochondria should down regulate to save energy. Wouldn't it be the opposite?

  • @chazwyman8951
    @chazwyman8951 ปีที่แล้ว +1

    A link to relevant studies would help.

    • @Alice_Walker
      @Alice_Walker 9 หลายเดือนก่อน

      " Low fructose and low salt diets increase mitochondrial DNA in white blood cells of overweight subjects"
      R Hernández-Ríos et al. Exp Clin Endocrinol Diabetes. 2013 Oct
      Some very basic digging on pubmed finds this study was called into question with the sample size too small and the variance of results too large to draw any meaningful conclusions.

  • @RichardFeuille
    @RichardFeuille 6 หลายเดือนก่อน +1

    Why did they not have a low fructose only arm?

  • @aliciastanley5582
    @aliciastanley5582 ปีที่แล้ว

    So how low is low enough sodium. How much sodium should we have per day?

  • @kennyg1358
    @kennyg1358 9 หลายเดือนก่อน

    How do I increase midoclorians?

  • @DanielTrevorOnline
    @DanielTrevorOnline ปีที่แล้ว +8

    But wait, 6 grams of salt/sodium is NOT a low sodium diet.

    • @medini2
      @medini2 ปีที่แล้ว

      salt is an enzyme inhibitor, so it can't be that great. need All my enzymes.

  • @YasminA-jm9zs
    @YasminA-jm9zs ปีที่แล้ว

    Information, great. Skin, glowing. Jawline, sharp.

  • @williamdgurley421
    @williamdgurley421 3 หลายเดือนก่อน

    I wish they would have added one more arm to this study, low fructose only.

  • @chazwyman
    @chazwyman 9 หลายเดือนก่อน

    Since the body cannot use fructose except in small amounts in the gut, and only through conversion in the liver to fat, what is the body doing converting sugar into fructose? What use is endogenous fructose?

  • @patrickp8315
    @patrickp8315 11 หลายเดือนก่อน +1

    Does this apply for regular weight subjects?

    • @teresamexico309
      @teresamexico309 2 หลายเดือนก่อน

      I do not think so and It is always missing that info in many studies, besides 6 gr salt per day is not a low dose.

  • @hartvenessa
    @hartvenessa 4 หลายเดือนก่อน

    How does damaged mitochondria stop weight loss?

  • @johnbgoode847
    @johnbgoode847 ปีที่แล้ว

    Can you do a deep dive on inhalation of Hydrogen Gas relative to its ability to stop free radical damage and protect Mitochondria..?

  • @horiadragoiu
    @horiadragoiu 9 หลายเดือนก่อน

    Mindblowing

    • @Alice_Walker
      @Alice_Walker 9 หลายเดือนก่อน

      If you do a little digging on pubmed you'll find this study was called into question with the sample size too small and the variance of results too large to draw any meaningful conclusions.
      The study is called "Low fructose and low salt diets increase mitochondrial DNA in white blood cells of overweight subjects"
      R Hernández-Ríos et al. Exp Clin Endocrinol Diabetes. 2013 Oct

  • @richardlamos1436
    @richardlamos1436 11 หลายเดือนก่อน +1

    I experimented with my own body and salt mixtures and now make and use a mix of 25% KCl and 75% Himalayan salt , all group up and mixed well.

    • @Corteum
      @Corteum 9 หลายเดือนก่อน

      What does it do?

    • @mytravls
      @mytravls 3 หลายเดือนก่อน

      Where do you get Potassium chloride?