Duchenne & Becker muscular dystrophy - causes, symptoms, treatment & pathology
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- เผยแพร่เมื่อ 10 ส.ค. 2016
- What are Duchenne and Becker muscular dystrophy? Muscular dystrophy is where the muscles weaken and lose muscle mass; in this case, both Duchenne and Becker muscular dystrophy are caused by a genetic mutation in the dystrophin gene. Find our full video library only on Osmosis: osms.it/more.
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I have Becker muscular dystrophy an crebel Paulsy Iam age 22 hopefully I live a long life
Codey Horn
I have Becker's MD and I'm a male age 47 live in Portland, Oregon
How old where you when it was disgnosed?
Codey Horn me too
Codey Horn hey I have the same thing
Live long
I have BMD i am 17 now with basic symptoms ☺️ But i use to live my life normal without taking burden 😊
shout out to my dad who has MD. he's the strongest man i know and i love him with all mt heart, and am so happy that he is still here, although walking is hard for him.
All I have to say is may God bless him with all the kindness and love present in the world
I am a 4th-year medical student and today I made a friend in the hospital with Becker muscular dystrophy. He is 40 years old and has been living in the hospital for many years because of the complications and need for monitoring. Anyway, I just wanted to say that he has literally the best personality, polite, and funny. I really admire him for educating himself and becoming the person he is now, also his the kind of person that you would never get bored while talking to him. Words wouldn't be enough to describe him. God bless him. Just wanted to say have some faith, it is the beginning of a long journey be strong.
Just lost a family friend with DMD. He was 36 years old. Rest in heaven, Jose, where there will be no more suffering ❤ we miss you
Same I Lost A Friend On June 3rd 2024
I'm on my third pathophysiology course of my nursing program because of you, you've carried me through these courses ❤❤❤
Thanks for making us part of your medical studies, Sukhmani! 🥰❤️🙏🏼
We've updated this video! The previous version spelled scoliosis wrong.
Wow you re uploaded the whole thing for one misspelled word. Thank you so much Osmosis. Please never get tire of making videos like this. It would really help students studying in medical field so much
We take accuracy really seriously and do our best to help student learn this information in a fun and easy way. =) Glad you found it helpful.
+Osmosis This channel is the best! Amazing work guys !
+Osmosis How did you spell it before?
I have excelled in all my path papers on the basis of your videos ❤️.
Thanks . You are a gift from God .🤩
For all of you guys out there with functioning muscles... you are very, very, very lucky. I have DMD, and it is the worst thing you can think of. I wouldn't wish this on my worst enemy.
Minion12 GT No, my brother has DMD and he hasn't taken a step in past 6-7 years. He'll be 20 soon.
We are doing everything we can for him. Not everyone with this condition can walk! Most of them don't live past their mid 20's so STFU!
Usually can walk before age 9
Sneak Nation Official Please research Dr. Robert Morse on TH-cam🍇💕I wish you luck on your healing journey!
I hope you are doing well
@@foodiepanda7430 maybe your brother shouldn’t have given up walking as much as possible
You guys have a knack for making complex concepts palatable ! Keep up the good work ! (y)
Will do - thanks Muhammad! =)
I have Becker's and just wanted to say thank you for this. It's quite difficult to find good information that easily describes what is going on. This is imo, the very best resource I've seen in 30 years!
Hey I have DMB too how you spend u'r life with it
@@brahimazzaf9376 that's a long answer. But to sum it up in a few words. I'm 34, finally on disability, and am trying to teach myself to program. I sleep a lot, sometimes up to 14hr, and am overweight. Most days I get nothing done from lack of energy and depression. Watch a lot of TV. And desperately want my life to change, but zero energy to do so.
So... Take from that what you will, lol. Everyone will experience life differently and will get done what they can. It's taken my 30 years to finally accept and be okay with my failures. It's a hard, tiring disease, and we do the best we can. That's all we can do right :)
I take 700mg carbamazapine daily... Which of course makes me drowsy all the time with little interest to do much. But it helps with the stiffness so I can actually move without the fear of falling each and every step.
Anyhow, hope this helped in some small way :P
@@SuinegNet I just wanna be normal I hope I don't have this shit and I won't even be able to get disability I'll be slaved till my skin starts rotting off by my parents
I will never forget the day I came across dr igho channel on TH-cam , I will always keep it memorable, thank you doctor for helping me cure my muscle dystrophy & pain completely , and putting a smile on my face , you made me feel more alive like never before , Thank you Dr igho
@@oladayoidowu226 Yeah he helped me getting my grandparents who were burried for at least four decades out of the grave and back to life! I am so thankful too.
Fallen in love with such a kind of easily understandable description of diseases in a short span of time.....Thanks a lot OSMOSIS
I think i have the rarest
Because i am 13 and can still walk but barely
Im a 3rd year medical student. I met a little 7y/o boy in the hospital yesterday who has DMD. Such a happy and spirited child. May God protect him and his parents. Thanks for the video!❤
This give me 90% of the answers need for my 150 point project
My little sister has a best friend who has DMD. He’s so sweet and it’s so horrible. His condition is getting worse, he’s repeatedly told her she needs to get ready to move on because he’s gonna die. She won’t accept it.
thats me with my family, they keep saying if i hold on theyll find a cure, ive been knowing it wasnt going to happen in my lifetime. i get so mad when they say " its ok we can try it again later"....i cant, i dont have that time. They are so focused on making sure i think im alive that i cant live a normal life...im 22 living with my parents and even when im working they have to check in to see how im doing because theres been times i was going to pass out and she had to pick me up while yelling at my boss, i feel bad but it was my fault for passing out but i still try to see the good things in life
@@r.j.9822 i wish you all the best🙏 may Allah help you live your life as you want it
Please help me with the cure, if there is any
Thank you so much you literally explained an entire lecture in just 7 minutes 👏🏼👏🏼👏🏼
You're very welcome! 🥰
My dad had Becker's muscular dystrophy, he was the best person I ever knew. He died at 41.
Rest In Peace ❤️
Hello, my father has the same illness could I talk to you? Do you use instagram?
May allah grant him jannah ❤️
I also BMD .most people dont care us😪😪😪
@@viraj9931Do you walk? How old are you?
I love my brother and he's my world and I can't imagine life without him in it. I've noticed my brother sleeping more but that's about it.
have been dealing with muscular dystrophy for the past 7 years until i got review online about Dr Isibor on TH-cam about his healing abilities through herbs and body cleanser and I contacted him after 14 days of treatment I felt better and completely cured!
@@juliadanielle6882can u send me his account?
i really love watching these videos. its educational and not boring at all.
such a nice short video that states all points without beating around the bush :) thank you so much this helped me understand it easily
may god bless and have mercy upon anyone with this
I have this and I've lived a more than gloriousll life... Trust me it only makes you stronger....... We stand because we were meant to stand out😊
Need me some muscular dystrophy in my cheeks. Finna get that hollow cheek
Fuck God, why would this even be a condition. Why would God put an innocent child through this!
Thank you I have Becker’s but at least It has not affected me so much yet
@@AvoozlPlays omg you really are delusional
I am suffering from it but don't know which type of it I am 23 now and wheelchaired I am graduate now and want to live long and become a teacher of history
What a helpful video! thank you for helping me pass my exam :)
Thank you so much!
i needed to repeat watching the video so i can understand the cellular and the genetic level.
Thank you very very much.
This video has helped me a lot with my human growth and development class! Thanks a ton. ✨☺
Glad it helped, Janae! 💖
my little brother is leaning towards a diagnosis of muscular dystrophy and my whole family is terrified. we want him to live a happy healthy long life so i’m studying up and planning on becoming a doctor or scientist, and planning on studying for a cure.
Does anyone else in your family have it, as its passed on from the mother the son(s). And daughters become the carriers.
@@voxtek no, its either started at my mother or him himself. We’re pretty sure he has Duchenne but we believe it’s going to be a slow journey to a point where he even just needs a wheelchair, but as of now we’re taking it one step at a time.
@@madisonswartz2571 have been dealing with muscular dystrophy for the past 7 years until i got review online about Dr Isibor on TH-cam about his healing abilities through herbs and body cleanser and I contacted him after 14 days of treatment I felt better and completely cured!
@@juliadanielle6882 we need more people like you ❤️❤️❤️ thank you for sharing
What was the symptoms.. can you pls mention?
Your channel is very helpful to study this diseases. Thank you
became an instant fan of your videos
Thanks for all your videos , I will make sure that if I became a doctor I will donate for you All.
I just loved this explanation. Thanks a lot.
The perfect explanation...
You don't need to watch any other video for DMD after this one
My Childhood dream was to become a fighter Pilot but this thing destroyed everything. I fucking hate my life
My childhood dream was to not be homeless with a horrible disease but now I can see to my future and that is exactly what will happen once I can't provide anything anymore
I have BMD
I'm 47 a male.
I'm Still walking but with a cane and walk very slow
I'm still driving a car too
I was diagnosis with Becker's muscular dystrophy at age 29
I'll be honest I'm having a real hard time mentally dealing with muscular dystrophy at 47
I like to stay busy doing stuff but I can't bend down pick stuff up that I drop alot because my right arm has gotten very weak in the 2 years
Stay strong, sending you love
Bro, please seek physiotherapy. It will improve ur life condition. It's the mainstay of treatment.
See @I feel good's comment above she talks about FDA study really hope that will help you..
really hope your still doing well
Hey, If you want to talk about it I‘m here..
thank you guys!!! really this is amazing great job !
That was excellent! Thank you for your efforts
I learned so much from this video. I'm 21 years old with Becker MD and yet have never learned this much about the disease. Thanks
have been dealing with muscular dystrophy for the past 7 years until i got review online about Dr Isibor on TH-cam about his healing abilities through herbs and body cleanser and I contacted him after 14 days of treatment I felt better and completely cured!
Very informative, thank you.
There's a special place in Heaven for people that make high quality, easily accessible educational resources
Amazing video, keep it up!
Gowers sign animated drawing was exceptional!! Osmosis is amazing.
Thank you so much, Sanjay! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on TH-cam? Check it out here: bit.ly/2u35D6J
I am so mesmerized by the website which I have purchased for my Step 1!! It's amazing. Got a question based on spaced repetition, should these videos be watched randomly or subject by subject? Do all 93 videos of Pathophysiology contain all of the organs on that page (especially Cardio)?
Love osmosis, for giving me all I need to know about topic in short time . ❤️
Happy to help, Komal! 🙏🏼
Excellent explanation!
excellent presentation...so far the best
Just the Perfect Cute Videos for my Medical Studies!!! It's my Third year and still tagging along with you. Thankss. Keep them coming. ☺️✨
Wow! Thanks for making us part of your medical education! ❤️
@@osmosis I'm glad to be a part of Osmosis fam.
What!!!!! This is very useful, thank you I appreciate your effort💗💗💗
Glad it was helpful, Mar! ☀️
Very helpful thank you!
THANK YOU OSMOSIS VERY HELPFUL 💗👏
thank u a lot for explaining the disease ... i love your channel. god bless u🤗😆
Awesome work!! that complex disease is soo simple now! :-)
superb explanation... thanx..
Keep creating more such videos love your channel
Thanks, Dr. Vikram!
You guys are flipping awesome!!!!
Very nicely explained
Just for some more info, I'm an interesting case. Diagnosed at 5 (DMD), symptoms at this age, but did well past wheelchair stage, diagnosed changed to (severe BMD), nonsense mutation determined, now 26, still fully mobile, driving with no mods, but still progressing. Waiting for Translarna to be approved in Canada.
We're sorry to hear that BelieveInTheShi3ld. Good luck, and take care!
Just a question, the video states that if a mother is a carrier 50% chance her boys WILL have it or could? I am the youngest of 3 boys and was the only one affected. Could it have been possible if none of us had it? 2 of us had it? All 3 of us had it?
What’s translarna? My nephew has just been diagnosed with dmd he’s only 6.. 🥺
the pain of beckers is ungodly. It feels like something is eating you on the inside of the muscle and believe me when I say I would give this to my worst enemy.
True..
I have Duchenne muscular dystrophy and it’s worse cause it starts way earlier then all the others I probably have the same pain as you tho there both the same but one is more slower and the other is faster
@@HeyBoss-ve9hg my brother's 6 and he has identified with DMD ....can u pls tell what is your age and what condition do you suffer?😢
Your videos are amazing. Congratulations to the team :)
Your explanation is awesome!
Thanks, Julie! 😃
excellent video well done 👍🏼👍🏼👍🏼
Would like to know if there are more cases like my father. He is 66yo and just found out that he has Becker dystrophy. He is healthy and doesn’t show any symptoms.
He did the test because I was diagnosed carrier of the disease when I was pregnant. The geneticist ask automatically my mother to do the test but she is not a carrier that’s why they wanted to test my father as well. What a surprise for everybody when we found out.
have been dealing with muscular dystrophy for the past 7 years until i got review online about Dr Isibor on TH-cam about his healing abilities through herbs and body cleanser and I contacted him after 14 days of treatment I felt better and completely cured!
Great video and very clearly explained. I wonder about the inheritance description though. If mum is a carrier you say, "50% will end up having the mutation". Not necessarily so. Instead, there is a 50% chance of inheritance with each new pregnancy.
I was gonna comment the same thing. 50% chance of inheriting not 50% inheritance rate. Subtle but important difference
You're explanations are terrific.
PERFECT EXPLANATION-REALLY THX
You're welcome, Mohamed! 🥰
Fantastic demonstration 👍🏻
Thanks, Helen!
The enlarged calf muscles with BMD are maybe one of the biggest hinderences as the quad muscle has to work even harder as there is definetly alot more more weight due to the fatty tissue if only there was a way of gaining lean muscle in the calf or even reducing the fatty tissue it may help quality of life. Personally ive tried quite a few supplements like aloe vera and creatine but little results now im trying testosterone booster few weeks in there could be some extra strength overall and with your core, i will report back if anything more dramatic. I know they have done testosterone therapy for DMD and there have been benefits but that is pure form of testosterone perscripted by a doctor unsure if it would help BMD also.
Stay strong folks there has been breakthroughs so hopefully in the not to distance future we could have something. Im 32 btw with BMD and im doing fairly well still able to walk good distances and get up stairs slowly and at times disguise my condition altogether.
Some supplements that have encouriging data behind them: Liposomal Curcumin or CUrcumin with piperine. See: pubmed. Resveratrol 3 x day 500 mg, NAC ( N acetyl cystein) got very good results in mice but has side effects. Co Q10 (again would try the liposomal form). Green Tea estract (Epigallocatechin) seems to be promissing too, like epicatechin (some brands of dark chocolate have it in them). And while no tested for Duchenne nor beckers but in other muscular diseases: astaxanthin (again best in liposomal form) seems to be a good candidate. None of these will reduce whatever damage there has been caused already. But some, like resveratrol and epicatechin seem to have especially merit in people with BMD. Epicatechin because it acts on a substance that curbs down muscle formation. For Duchenne this is less interesting since that substance is already very low. But in most Becker patients it is pretty normal hence it getting cirbed down means (at lest intheory) muscle formation. Resveratrol showed very significant drops in CK levels in people with duchenne and becker nd that is the sign that muscle damage is significantly curbed down.
A very encouriging one but also in its infancy when it comes to research is N Acetyl glucosamine. In DMD mice the muscles got 50% stronger (which I have never seen in any mouse model).
If I were you and money permitting I would combine these after a good read of the literature that is available online. Most of these substances have been used by many people in large quantities without side effects so it seems to me they are worth a try. Good luck!
How are you now, how did everything work out
can u please elaborate how ur symptoms started and progressed over the years in detail? I'm suffering from severe weakness and exhaustion and want to know about bmd. Please help.
My younger brother has MD and I have no idea what it is. I had to look it up because I have never heard of it. I’m worried about him but I know he’s strong and he can get through it
Rooting for your brother as well! Hope our video was able to help. 🙏🏼
Thank you so much !
thanks man. I had a hard time figuring out the overall importance of dystrophin, before this video.
Can u plz make a video on Erb's muscular dystropy...???
love every video!
Please make one for Osteogenesis imperfecta :)
Thank you!
thank u soo much , that was an epic explanation
Glad you liked it! 😊
Great job
You may like to put this video under the Musculoskeletal Pathology playlist as well.
Thanks for the suggestion!
And another great video
You are my hero !
Thank you so much ❤️❤️
Lost my little brother because of DMD.. back then there was'nt any cure for this.. i hope everyone that has it have a long life because now they finally have a way to cure this.
I'm sorry for your loss, did he play any sports? I'm still trying to understand this.
@@nursing7420 no, it just started to happen at around age 7 for my brother.. i noticed he would just fall down while walking for no reason.. as years go by it became more frequent as if he was loosing strenght in his legs everytime he falls down.. eventually he could'nt walk anymore and had to be bedridden until he died after one day he went to a coma and died the very next day at the age of 22.
@@spynxz-_-8398 thank you for that. I’m a nursing student and want to do research yo one day find a cause and cute. Thank you again 🤍🙏
hi.the last I've heard is that there are no cure for it, can you kindly correct me.
@Spynxz
Thank you
I just hope they find a cure soon or something to slow the process, i'm 26 now and i'm really scared, they say those with the disease die a slow and painful death and which is what i'm terrified by the most.
thanks alot !
Thanks for helping at end moments.... m abt 2 write exms .... thanks for awesome explanation...😊
wow,impressed!
Very informative video! 🎉
Thanks, Brenden! 😊
thank's , it's so interesting
My friend has this and she’s in hospital her chest is really weak :(
Any treatment available for DMD ?
thanks
Sir, Can you tell about genetic inheritance/transfer of father affected with Beckers Muscular Dystrophy?
Does it also equally affects as carrier mother?
Love you Stefan ❤️❤️
hopefully I can live my life very greatly before I become too old, and ride all of the roller coasters that I can because that is my favorite activity....
have been dealing with muscular dystrophy for the past 7 years until i got review online about Dr Isibor on TH-cam about his healing abilities through herbs and body cleanser and I contacted him after 14 days of treatment I felt better and completely cured!
If anyone wanted to know what it is called when more of one X chromosome than the other is expressed by X-inactivation it is called skewed X inactivation
I think I got the speratic mutation for beckers becuase none of my late family has it. But at the same time my brother has it and it affects him differently than me. While I have the worst of it my brother has less of an effect. Apparently its rare, like 1% rare to have two brothers with different mutations of the same genetic disease.
i'm kindly asking for the pathophysiology
great video!
Thank you, Adriano! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on TH-cam? Check it out here: bit.ly/2u35D6J
Very helpful than you
Thank u very much 💙💙💙💙💙💙💙💙🌷🌷🌷🌷 appreciate 🙏🏻
I got diagnosed yesterday...
Im so sorry. Hiw are you doing now?
Thank you!!--!!!!! 🙏🙏
Thank you for watching, NouY Moua! Did you know that if you like & review us on Facebook then you’ll get access to our videos a day before they’re published on TH-cam? Check it out here: bit.ly/2u35D6J
My son is 16 and had had muscular weakness for a couple of years. Hes now being tetsed for MD, beckers & Limb Gurdel. Still awaiting blood and gentics results.
Ddoes anyone know anyone who was diagnosed mid teens and could tell me how it has affwcted their lives?
My uncle my brother and I all had different symptoms with our bmd. When I was born I had enlarged calves and my muscles are very sensitive to straining/cramping. My brother and Uncle didn't notice anything untill they hit puberty. My uncle grew to 6 ft 3 and had to walk on the tips of his toes at 16. He couldn't walk by 19. My brother only got to 6ft so he could walk somewhat normal but couldn't run anymore. I was fairly strong and run, athletic. But I would have to take frequent breaks to let my strained muscles relax. They would just start getting Tighter and Tighter until it was too painful to even put weight on that muscle. My condition started slowly switching to the same way my brother was with me at 25. My gigantic calves slowly disappeared. My brother became bedridden at 42. Im 39 still walking good enough. But my heart will fail befor i can't walk anymore. I got dilated cardiomyopathy with arrhythmia pretty bad. My brother and Uncle didn't get any heart issues or gastroparesis like I did.