Cryoscopic method in easy way

Adjustment of isotonicity by cryoscopic method involves addition of sodium chloride to achieve desired freezing point depression isotonic with body fluids. For this we have to calculate sodium chloride required by using a formula which should include concentration and volume terms. So in this video, we will discuss one practical example along with easy formula to calculate.
#isotonicity
#crysoscopic
#fpd

[@srishtisingh5458]

You made it too easy🔥

[@crafting49]

Sir, by using simple formula the answer wil be 0.137????

[@Snew288]

How 0.17 I don’t know how you calculate it

[@hijanahhusin1277]

Sir, your calculation for FDP require to produced NaCI should be 0.35 right? Because 0.52-0.17=0.35..Sorry if i am wrong😅

[@snehar7540]

Thank you sir🎉

[@hisanathasni5499]

Thank you soo much sir ❤❤❤

[@dilkhushprajapat6189]

Tnq

[@tikeshwarsahu6171]

Nice presentation sir please made more video related to physical pharmaceutics

[@megb8073]

Really helpful formula. what if there are two drugs, how do we apply to this formula?

[@chabaneaymen1018]

why did u use 1% nacl and not 0.9% ? is it up to whats asked of us to use ? it could be either ?

[@egpat]

We have to use 0.9% NaCl for adjustment of tonicity. But for calculation purpose we should compare it with 1% as the freezing point depression of the drug is given in terms of 1% solution.

[@asiya9088]

thank you! I finally understand this topic

[@egpat]

Glad it was helpful! Thanks for watching.

[@alphagonist4748]

Thanks💗

[@sheronjoseph3110]

Excellent👌🏽

[@madhubolem1864]

Really very easy to follow

[@egpat]

Glad to hear that. Thanks for watching

[@madhubolem1864]

Please provide tricks for white Vincent and sprowls method also sir

[@muntadherkh5655]

Great ❤️

[@ashish3198]

Please make video on class 2 method

[@abhinavinvincible122]

0.52-0.17=0.35🙏5:14

[@Lanakalana]

Omg thanku somuch

[@omarabdelbaset5448]

the formula answer is not 1.28 is 1.21 ! so the formula is wrong

[@egpat]

The formula given there is exactly correct and it is a simple trick for easy calculation. But within the video, 0.52-0.17 should have value of 0.35 which misplaced with 0.37. So if we put 0.35 there, both direct method and simple method will give 1.21 as answer. Thank you very much for notifying this correction and we will update it in description box. Thank you.

[@matamatason7213]

Thank u so much

[@siddhantbandekar7081]

What if freezing point of drug is not given in data

[@egpat]

For cryscopic method, freezing point depression of the drug is required. If it is not given, then we can try to adjust the tonicity by other methods like sodium chloride equivalent method and sprowls method.

[@ahmadfares5243]

hi to you evey time