Botox is used in Parkinson's patients as well! My dad got regular treatments to help with drooling. Might not sound medically necessary, but it can have a *huge* impact on independence and quality of life.
Great video! Captopril and Exenatide are the 2 on this list that have had the greatest impact on medical practice over the last 40 years, and they spawned much more targeted agents of their respective classes. Captopril initiated a hot debate (controversy) re: international research, it's an interesting story!
Hey!!! I love medical Monday’s 💖 they must take so much work, the videos are researched WAAAY deep in depth. Thank you for putting in the hours to create content like that.
I have arthritis in my elbow that interfered with my life. One day, I leaned back in the grass and got a bee sting on the elbow. The pain went away completely about 2 days after the sting, and didn't bother me for 5 years. Then I caught a bee and intentionally stung my elbow, and again, the pain left for about 5 years. This has become something I need to do every 5 years, but bees are getting harder and harder to find. But I feel that this should be studied, and I'm starting to develop arthritis in my hand, so I need to find more bees. Sounds crazy, I know, but it really works!
You can keep your own bees by maintaining a hive, like bee keepers do, though that would take a lot of work. Also, I'm pretty sure doctors use bee venom in medicine, so you could potentially just get a shot at the doctor. Easiest option might just be to plant a mini garden with flowers that bees like so you have access whenever you need.
If you live in the Eastern US (east of Missouri), bee balm is a native and easy to grow plant that is super attractive to bees 🙂 If you live in its native range it's basically 0 maintenance since that's where it grows naturally (at least that has been my experience). Bee balm is great for bees and many Native American groups have and still use it in multiple medicinal applications - it contains thymol which is the main active ingredient in modern mouthwashes.
Botox is also used sometimes in Cerebral Palsy which is really cool. I know someone who got the injections as a kid to be able to run. It loosened the muscles enough for him to learn how and now he goes for daily runs as an adult.
This was one of the most interesting videos I've seen in a while, my father had several very aggressive cancer surgeries that where pretty debilitating, so cancer paint sounds amazing. Thank you for the quality content and not being as clickbaity as about 95% of the stuff on TH-cam.
I love the fly mushroom (amanita muscaria) & deadly nightshade (atropa belladonna) pair. The most famous toxic mushroom & plant are antidotes of each other
Melarsoprol is also a pretty interesting one (although it wasn’t developed from animal toxin per se). It was developed from Arsenic as a treatment for late-stage African sleeping sickness. It is given as an IV, which is extremely painful to receive, and it kills 5-10% of the people who receive it. It also contains propylene glycol, a chemical used in certain kinds of antifreeze. Because of the propylene glycol, it actually needs to be stored in glass syringes because it will legitimately melt plastic ones. For a long time though, it was the only available treatment for late stage African sleeping sickness. It has saved a lot of lives, albeit receiving it is seemingly absolutely horrendous to experience.
I receive Botox injections in my left arm and left leg every 3-4 months to lower the levels of spasticity (also known as hypertonia) in my muscles. And I’ve been getting this treatment done ever since I was 11 years old. I have spastic hemiplegia cerebral palsy, which is why I get the treatment. It’s very helpful for people who have cerebral palsy.
Love the video, especially the comment about not killing everything that does not fit into our idea of soft and fuzzy, as long as we do not find a miracle medicine using mosquitos, fleas, and ticks. I did go to a seminar where they discussed that cone snail venom has a tremendous number of compounds that scientists are interested in seeing if they can be turned into medications.
"Scientists are increasingly turning to the most lethal corners of the animal kingdom... FOR DRUGS!" -Hank, 2020 What a beautiful line to take out of context
The problem with missing out on the benefits of species that we drive to extinction is that practically nobody will notice that we are missing out on those benefits. As a result, it's hard to get people to see the problem with driving species to extinction. They simply ask "What has that species ever done for us?". Hopefully, this video will help some of those people see the error in their ways. Thanks, SciShow!
This is one of the BEST episodes you have ever done. It just proves that everyone on this planet (including you and me!) was created for a reason. Our job is to figure out what those reasons are, and use them wisely.
My ex gf has MS. This one toxin to control immune response seems to be a real option. Something that might be more specific and therefore have less side effects. I hope they can make this work and of course hopefully develop a cure to this and other auto immune disorders. So while nature seems to have given us MS, it might also be the source of a treatment. As the saying goes, the dose makes the poison
@MrSlave00 interesting comment. Yes, I didn't do right by her hence the ex part. However, she was a wonderful person and I do hope her MS will not progress to the point where she will be in pain. Sadly, most MS does progress so I do hope she will be witness to a cure to this condition. Such a cure would likely also be based on research which could lead to an effective treatment for conditions like ALS
Big pharma rarely develops cures. They make more money treating stuff. The cure would be more likely to exist in natural form and not require any scientific development. Pharma would just patent a specific peptide and go with the business model that profits the most. Addictive substances are especially lucrative.
As a chemist, I got a hard one on Cantharidin. It's surprisingly simple for a biological molecule, could be probably synthesised with common lab chemicals in 3 steps and is more deadly than prussic acid... Even most nerve "gases" would be more complicated to produce (difficulty increasing from Sarin over VX to Novichok).
Wow. That is now one of my favorite SciShow vlogs I have ever come across. The conclusion is stunningly brilliant and uniquely eye-opening. Thanks Hank and thanks to your team of writers and content creators.
As a kid i collected shells, conesnail shells i got from these bags of mixed shells sold in some stores. Later i learned about them and was surprised them being so dangerous.
I've psoriatic arthritis and it's painful! So #6 interested me very much! I quit opioids 5 yrs ago and I get to wake up every day without that terrible burden! I refuse to take pain meds and meds like humira bc it lowers the immune system and I don't want to do that! Thanks for the video
As a suffering of lupus in super hyped for number 6. I can’t wait to someday live without horrible pain from my immune system attacking my kidneys, tendons, muscles and joints.
Cool Breeze my condolences. Sorry for your loss. I’m fortunate enough to be a good responder to medications and so most of the time I live a very normal and athletic life. My heart goes out to those more severely affected. Hope others one day find relief.
The scientific name for the toxin in these animals is called jerkocloric toxin. In some studies, scientists have discovered it can be used as an antidepressant because you feel better about yourself when you realize that creature is probably some fat neckbeard behind a keyboard in his mom's basement jacking off to his anime girl bodypillow.
Smart ppl: I'm gonna see if this weird sh will save lives. If not save, at least benefit from. Me: _pretends like I can play flute, to see if snakes will react bc 🤷🏻♀️ idk, cartoons_ . Get hypnotized by my human activities, damnit! Also, I need to hear it for all the guinea pigs out here. Like the actual animals. Poor things really are saving lives.
A while back I read an article that said that a new pain control medication from cobra venom. It is apparently non addictive and fast acting. Has anybody heard about this new med and when it might come to market
I wonder what has changed with all of these since this video came out. As someone with three autoimmune diseases, one of which I've suffered from since birth, this whole video usnvery exciting to me. The fact that I'm on none of these and it's 3 years from then, makes me a little less so. :s
But then those nerdy boffins will invent a way to synthesize the stuff from something cheap like dirt. Then wodayagunnado, hire Jamie Oliver to come up with some scorpion recipes?
That last point was something that was on my mind the entire video thank you for addressing that! I was like "what if we already killed off the species of animals/plant that not only Stain cancer but eliminated it..", but big pharma would find a way to make it super expensive and inaccessible because if no one has cancer, there's no money to be made
To the students in Mrs. Willard's 6th grade Science class, thank you for sponsoring this video. This is really fascinating information. I appreciate your efforts to share it with me So let me return the favor and give you something I have found valuable. Often the smartest answer is, "I don't know." Followed by, "lets see if we can figure it out." Don't be afraid to keep asking a question till you find an answer that makes sense to you. Be specific. "How does "x" make "y" function?" I use this piece of info daily, if not hourly. I work for an engineering firm. I back-check the drawing packages the Engineers, Designers, and Drafters create to make or build things. I go through all the drawings to confirm all of the measurements, materials, and layouts needed to build the project are included and acurate. I also make sure the info in the plan drawings are the same as the corresponding elevations and sections. It's my job to ensure the people building that project will have all the data needed to do it. If something doesn't make sense to me, it won't make sense to the person building it. Thing is, if they find it during construction, it could cause delays, changes or shut down a job and be expensive. Me saying, "this doesn't make sense to me." "Why is it like that?" Save hundreds, sometimes hundreds of thousands, of dollars for my company's clients. I didn't know this job existed when I was in 6th grade. Honestly, when I was 12, I didn't believe I would ever be good at anything. I struggled to understand stuff. Mainly because I was afraid my questions were stupid. I didn't want to be humiliated. So instead of learning the answers, I remained ignorant. I found a teacher that forced me to ask questions. He would never give you enough information to figure something out, unless you asked a couple questions. Finding the answers is what made me become good at something. Good at a lot of something's. Doing something well, is one of the best feelings you will ever have. May your lives be full of that kind of success.
Thank you for this program. One thing he didn't mention, is a protein from the baby Florida rattlesnake is useful in cardiac catheterization procedures.
WOW! So informative and absolutely hilarious all at the same time :) Jessica McDonald, bravo on yet another brilliant script! Hank - your comic timing is, as ever, perfect! "... useful to the snakes because things their meals need to flee, like brains and muscles, don't work so well without blood..." I've watched that line like 50 times and it just keeps getting funnier!!
I know the gila monsters venom undergoes a process to lower peoples blood sugar, but it got me thinking. Since the venom isn't that harmful to humans, do you think in a Macgyver type of emergency, you could get a gila monster to bite someone and potentially save their life? I'm not so medically inclined when it comes to these things, I'm just wondering if it would be possible?
I have always been interested in poisons and toxicology, although never terribly interested in death. The history of the synthesis of strychnine is fascinating. Well, you know, as far as organic chemistry can be.
Study of animal and plant venom is fascinating in drug research. Even if the venom itself is not useful, many times its method of action (or the way it works in the body) can lead to whole new classes of drugs that work in ways never even imaged a few years ago. At the same time we learn new things about how body does things like react to pain or cause neurological disorders, when we study how the venom's/toxins interact with the body.
An idea for a followup video: Toxic plants or plants that can harm animals/humans but are used for their medical potential. I think about substances like bromelain which is used in patients with burn injuries. Normally bromelain digests meat and flesh...
Perhaps Gila monsters have that compound to make their prey less energetic? With less sugar in the blood, they might become exhausted easily. Idk, just a random guess.
That one about GLP1 was very useful. I’ve been struggling with being overweight for a while as well as higher than normal blood sugar. Since I need a prescription for glp1 drugs, I found berberine and I’m going to give that a try.
The south American pit vipers he's talking about is the bothrops genus. Specifically the jerracasu and layacpris (im horrible ar spelling) but they are so medicinally significant right now. I believe it's the most saut after venom right now. Venomology is amazing and helps save man kind from.
I still have a scar from a big, ugly blister I accidentally got from a blister beetle about 45 or so years ago as a kid. Best I could figure out, it got caught between my wrist and the ground, and didn't like it there. I didn't like the sensation I immediately got, either. Screamed my head off for a little bit, in fact, because it HURT!
Don't take Hank as an authority on correct pronunciation. He, like many, many others, mispronounces "nuptial" as though the -tial part is pronounced like the -tual in "mutual", when it should be pronounced like the -tial in "martial". nup-shul, not nup-shoo-al
There are quite a number of potential poisons that are deadly enough and readily available to non-chemists. Except for these bugs, pretty much all of these critters are dangerous to harvest. Plants on the other hand are pretty easy. Also engineering a food-poisoning by growing bacteria is not that difficult.
If you know a drug dealer grab a bunch of acid, it's hallucinogenic but a "safe" dose is in nanograms. Although it's illegal and I obviously don't have an experience with it.
"Sola dosis facit venenum," or "The dose makes the poison," is a founding principle of toxicology. Everything... and I do mean EVERYTHING, as in every single substance in existence, yes even whatever thing you're thinking of to try to make a joke... is toxic in the right dose.
"All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison." ~ Paracelsus, born Theophrastus von Hohenheim
Botox is being used for stomach pain now too! Here in Tucson the north west hospital actually has a whole thing about it. I myself was treated with botox injection to stomach. My pain went away! The only down side is you get resistant to botox and it doesnt continue to work as well. But they use it as a test for a procedure that can be done. If botox helped you, this procedure will help you. Just got back from my surgery been healing 5 weeks. Another 3 and I should be back to normal. Stomach now the size of a tangerine.
Just learned a heck of a lot in the last 12 minutes annnnnnd I'm a pharmacist. While I might have known about our old tried and true meds, the new research is fascinating! Maybe it's just so fascinating because of the presentation, I dunno.
Hopefully the tumor paint only comes in one colour. I can think of an ex-girlfriend who'd spend weeks trying to decide which colour the surgeon should use.
My boyfriend was on the expiratiantal test board! The gilla monster diabetic medicine was AWESOME!!! HE ONLY had to do his treatment every 3 MONTHS! His blood sugar was like a normal person! No more insulin SHOTS for 2 yearz! Then tbe study was over! (He even lost 35 lbs!)
My grandfather (ojiichan) used to catch and kill Mamushi (Japanese Pit Viper Gloydius blomhoffii,) and place them in a bottle then fill the bottle with Soju a Japanese distilled spirit. He'd let it age for about 6 months at room temp. I remember he had several bottles of this "Mamushi Sake" at various stages of aging. He'd drink a shot of the aged stuff every morning for medicinal purposes supposedly to keep him healthy. He was always very healthy so maybe it worked. On Okinawa they make a similar potion but they use their local venomous snake the Habu (Protobothrops flavoviridis also a Pit Viper). I've had this stuff, and I found it actually tasty.
As alcohol can denature proteins, I would argue that most likely any venom was deactivated. Maybe your grandpa was healthy because of good diet, regular exercise and good genes. Though drinking snake soaked sake sounds pretty bad ass.
Botox was the best thing I ever did for my face. Cost me a fortune because Medicare (Australia) doesn't cover it for tension type headaches - literal muscle spasms - but they do for prophylactic treatment for migraines. I don't understand their logic...
SciShow, this was a great episode. Some time in the future, would you be able to discuss toxicological synergy/ synergism? That is a very interesting topic, how some things in and of themselves are not so effective until you mix them with other chemicals.
Botox is used in Parkinson's patients as well! My dad got regular treatments to help with drooling. Might not sound medically necessary, but it can have a *huge* impact on independence and quality of life.
AV C. Cannabis is also VERY effective in the treatment of Parkinson's, as well as a myriad of other ailments! Don't knock it until you've tried it.
Carol Jo Martin Maybe it'll even be legal by the time I have to worry about PD.
Many of these pharmaceuticals don’t sound life-saving, that’s true. They may make life worth living, however.
Botox is used to treat hyperhidrosis as well
AV C okey mr. scientists🤷♀️😳😂
Great video! Captopril and Exenatide are the 2 on this list that have had the greatest impact on medical practice over the last 40 years, and they spawned much more targeted agents of their respective classes. Captopril initiated a hot debate (controversy) re: international research, it's an interesting story!
Chubbyemu
Hey! Cool seeing you here. I really enjoy your videos - they are very informative and entertaining!
Hey!!! I love medical Monday’s 💖 they must take so much work, the videos are researched WAAAY deep in depth. Thank you for putting in the hours to create content like that.
Chubbyemu make us a video Senpai
Good to see you here
Love your Medical Mondays
The best thing the TH-cam algorithm recommended to me
A medicine youtube channel commented on a scishow video, this is how his kidneys shut down.
I have arthritis in my elbow that interfered with my life. One day, I leaned back in the grass and got a bee sting on the elbow. The pain went away completely about 2 days after the sting, and didn't bother me for 5 years. Then I caught a bee and intentionally stung my elbow, and again, the pain left for about 5 years. This has become something I need to do every 5 years, but bees are getting harder and harder to find. But I feel that this should be studied, and I'm starting to develop arthritis in my hand, so I need to find more bees. Sounds crazy, I know, but it really works!
Carol Jo Martin. This type of therapy has been used for quite some time. You can check some info here www.healthline.com/health/bee-venom-arthritis
th-cam.com/video/PBgHGKrvfg0/w-d-xo.html for SciShow article on bee venom therapy.
You can keep your own bees by maintaining a hive, like bee keepers do, though that would take a lot of work. Also, I'm pretty sure doctors use bee venom in medicine, so you could potentially just get a shot at the doctor.
Easiest option might just be to plant a mini garden with flowers that bees like so you have access whenever you need.
If you live in the Eastern US (east of Missouri), bee balm is a native and easy to grow plant that is super attractive to bees 🙂 If you live in its native range it's basically 0 maintenance since that's where it grows naturally (at least that has been my experience). Bee balm is great for bees and many Native American groups have and still use it in multiple medicinal applications - it contains thymol which is the main active ingredient in modern mouthwashes.
i live in a maya part of Mexico.. this is a common treatment here. glad you discovered this.
Botox is also used sometimes in Cerebral Palsy which is really cool. I know someone who got the injections as a kid to be able to run. It loosened the muscles enough for him to learn how and now he goes for daily runs as an adult.
I have CP too. And it helps me a lot.
I actually do inject snake venom to make my workouts more challenging
Muscle Hank there you are!!!!
#MuscleHankVsJustinY
Ok terminator
They help me get a 12h erection to please my right hand
Beat up hustle hank for me
This was one of the most interesting videos I've seen in a while, my father had several very aggressive cancer surgeries that where pretty debilitating, so cancer paint sounds amazing. Thank you for the quality content and not being as clickbaity as about 95% of the stuff on TH-cam.
I love the fly mushroom (amanita muscaria) & deadly nightshade (atropa belladonna) pair. The most famous toxic mushroom & plant are antidotes of each other
Melarsoprol is also a pretty interesting one (although it wasn’t developed from animal toxin per se). It was developed from Arsenic as a treatment for late-stage African sleeping sickness. It is given as an IV, which is extremely painful to receive, and it kills 5-10% of the people who receive it. It also contains propylene glycol, a chemical used in certain kinds of antifreeze. Because of the propylene glycol, it actually needs to be stored in glass syringes because it will legitimately melt plastic ones. For a long time though, it was the only available treatment for late stage African sleeping sickness. It has saved a lot of lives, albeit receiving it is seemingly absolutely horrendous to experience.
I receive Botox injections in my left arm and left leg every 3-4 months to lower the levels of spasticity (also known as hypertonia) in my muscles. And I’ve been getting this treatment done ever since I was 11 years old. I have spastic hemiplegia cerebral palsy, which is why I get the treatment. It’s very helpful for people who have cerebral palsy.
I have CP too. And it helps me a lot.
Love the video, especially the comment about not killing everything that does not fit into our idea of soft and fuzzy, as long as we do not find a miracle medicine using mosquitos, fleas, and ticks. I did go to a seminar where they discussed that cone snail venom has a tremendous number of compounds that scientists are interested in seeing if they can be turned into medications.
Poison and medicine is just a difference in strength or concentration.
and use.. that's a bit oversimplified...
john pardon he is ralkimg about the saying "the dose makes the poison"
yeah, im fairly sure ANYTHING can kill you if you have too much of it.
Amen. I need to get that postered. With a small modification
Aeron Gray You wont die from air
"Scientists are increasingly turning to the most lethal corners of the animal kingdom... FOR DRUGS!" -Hank, 2020
What a beautiful line to take out of context
The problem with missing out on the benefits of species that we drive to extinction is that practically nobody will notice that we are missing out on those benefits. As a result, it's hard to get people to see the problem with driving species to extinction. They simply ask "What has that species ever done for us?". Hopefully, this video will help some of those people see the error in their ways. Thanks, SciShow!
what was that highschool grad from 40 years ago dealing with that they needed to compare morphine to cone snail toxin??
😂
More yet, how do you quantify pain? Surely my snake venom can be 2001% better than morphine
'Super toxic critters' is a great name for a band.
or my ex wives
Or “Death Stalker Medicine”
@@rmfleming69 dude you're the common denominator lol
@Justin Craig get bent you shmuck
Yessss!
This is one of the BEST episodes you have ever done. It just proves that everyone on this planet (including you and me!) was created for a reason. Our job is to figure out what those reasons are, and use them wisely.
My ex gf has MS. This one toxin to control immune response seems to be a real option. Something that might be more specific and therefore have less side effects. I hope they can make this work and of course hopefully develop a cure to this and other auto immune disorders. So while nature seems to have given us MS, it might also be the source of a treatment. As the saying goes, the dose makes the poison
@MrSlave00 interesting comment. Yes, I didn't do right by her hence the ex part. However, she was a wonderful person and I do hope her MS will not progress to the point where she will be in pain. Sadly, most MS does progress so I do hope she will be witness to a cure to this condition. Such a cure would likely also be based on research which could lead to an effective treatment for conditions like ALS
Big pharma rarely develops cures. They make more money treating stuff. The cure would be more likely to exist in natural form and not require any scientific development. Pharma would just patent a specific peptide and go with the business model that profits the most. Addictive substances are especially lucrative.
Did you ever experiment with the venom? My father has ALS and we are looking at trying neurotoxins as medicine.
@@macbuff81 you cheated on a girl with MS ? that's despicable.
As a chemist, I got a hard one on Cantharidin. It's surprisingly simple for a biological molecule, could be probably synthesised with common lab chemicals in 3 steps and is more deadly than prussic acid... Even most nerve "gases" would be more complicated to produce (difficulty increasing from Sarin over VX to Novichok).
Wow. That is now one of my favorite SciShow vlogs I have ever come across. The conclusion is stunningly brilliant and uniquely eye-opening. Thanks Hank and thanks to your team of writers and content creators.
Wait, the pit viper venom _lowers_ blood pressure? I just look at one and I feel my heart race and blood pressure rise!
I wish you were everywhere, your comments are gold
Yes it does. It can lower your blood pressure to zero.
Wimp! 😎😄
I wonder if you could balance the venom and the panic to have a normal blood pressure.
The venom’s job is specifically to counteract the fight-or-flight response-they said that.
This man really said 1980 and half a century ago in the same sentence. How time flies
Fantastic narration! Fascinating information! Thank you very much. I will definitely share this video with family and friends.
As a kid i collected shells, conesnail shells i got from these bags of mixed shells sold in some stores. Later i learned about them and was surprised them being so dangerous.
I've psoriatic arthritis and it's painful! So #6 interested me very much! I quit opioids 5 yrs ago and I get to wake up every day without that terrible burden! I refuse to take pain meds and meds like humira bc it lowers the immune system and I don't want to do that! Thanks for the video
I love watching TH-cam videos that have actual informative, well-presented content. Thank you, ScIShow!
As a suffering of lupus in super hyped for number 6.
I can’t wait to someday live without horrible pain from my immune system attacking my kidneys, tendons, muscles and joints.
Cool Breeze my condolences. Sorry for your loss. I’m fortunate enough to be a good responder to medications and so most of the time I live a very normal and athletic life. My heart goes out to those more severely affected. Hope others one day find relief.
I love list episodes! Fascinating, i cant wait to drop this info casually into conversations
Michelle Koh
That's what I live for
You're my kind of person!! I do that as well!
Always informative, thanks.
As a Type 1 Diabetic, thank you for specifying that you were referring to Type 2 diabetes @4:40. :)
While you can get something useful from most toxic creatures, you won't find anything from the average TH-cam commenter
[ Duwang_Mn ] haha
Yeup. And they can be SUPER TOXIC lol
The scientific name for the toxin in these animals is called jerkocloric toxin. In some studies, scientists have discovered it can be used as an antidepressant because you feel better about yourself when you realize that creature is probably some fat neckbeard behind a keyboard in his mom's basement jacking off to his anime girl bodypillow.
What a beautiful [D_wang].
chew
@@cameronb7161 😂😂😂😂😂😂😂😂😂
That moment, when you realize, that everything that can kill us, can also save our lives, the irony.
what doesn't kill you makes you stronger. Like building up an immunity to Iocaine powder. (Princess Bride)
@Amilah seth macfarlane in million ways to die in the old west: Everything that isn't you, is trying to kill you.
Smart ppl: I'm gonna see if this weird sh will save lives. If not save, at least benefit from.
Me: _pretends like I can play flute, to see if snakes will react bc 🤷🏻♀️ idk, cartoons_ . Get hypnotized by my human activities, damnit!
Also, I need to hear it for all the guinea pigs out here. Like the actual animals. Poor things really are saving lives.
Gosh I am a nurse and you explained diabetes in less than a minute than i had in my training!
Fascinating topic! One of my favorite SciShow episodes.
A while back I read an article that said that a new pain control medication from cobra venom. It is apparently non addictive and fast acting. Has anybody heard about this new med and when it might come to market
Oxycontin was apparently non addictive 2
I wonder what has changed with all of these since this video came out. As someone with three autoimmune diseases, one of which I've suffered from since birth, this whole video usnvery exciting to me. The fact that I'm on none of these and it's 3 years from then, makes me a little less so. :s
I guess I'm gonna quit my job and become a scorpion breeder
But then those nerdy boffins will invent a way to synthesize the stuff from something cheap like dirt. Then wodayagunnado, hire Jamie Oliver to come up with some scorpion recipes?
I have had cantharidin used on warts. And by far it's the most painful but most effective treatment. It works really well
That last point was something that was on my mind the entire video thank you for addressing that! I was like "what if we already killed off the species of animals/plant that not only Stain cancer but eliminated it..", but big pharma would find a way to make it super expensive and inaccessible because if no one has cancer, there's no money to be made
To the students in Mrs. Willard's 6th grade Science class, thank you for sponsoring this video. This is really fascinating information. I appreciate your efforts to share it with me
So let me return the favor and give you something I have found valuable. Often the smartest answer is, "I don't know." Followed by, "lets see if we can figure it out." Don't be afraid to keep asking a question till you find an answer that makes sense to you. Be specific. "How does "x" make "y" function?"
I use this piece of info daily, if not hourly. I work for an engineering firm. I back-check the drawing packages the Engineers, Designers, and Drafters create to make or build things. I go through all the drawings to confirm all of the measurements, materials, and layouts needed to build the project are included and acurate. I also make sure the info in the plan drawings are the same as the corresponding elevations and sections. It's my job to ensure the people building that project will have all the data needed to do it. If something doesn't make sense to me, it won't make sense to the person building it. Thing is, if they find it during construction, it could cause delays, changes or shut down a job and be expensive. Me saying, "this doesn't make sense to me." "Why is it like that?" Save hundreds, sometimes hundreds of thousands, of dollars for my company's clients.
I didn't know this job existed when I was in 6th grade. Honestly, when I was 12, I didn't believe I would ever be good at anything. I struggled to understand stuff. Mainly because I was afraid my questions were stupid. I didn't want to be humiliated. So instead of learning the answers, I remained ignorant. I found a teacher that forced me to ask questions. He would never give you enough information to figure something out, unless you asked a couple questions. Finding the answers is what made me become good at something. Good at a lot of something's. Doing something well, is one of the best feelings you will ever have. May your lives be full of that kind of success.
I don't know why, but this feels like an old-school episode of SciShow, and I LOVE that!
You should consider a video on "bee therapy" and whether this truly helps with arthtitis or not.
6:23 anyone who took chemistry see's those di-sulfide bonds. Good stuff.
Thank you for this program. One thing he didn't mention, is a protein from the baby Florida rattlesnake is useful in cardiac catheterization procedures.
Actually, Botax is now helping people with disabilities by helping us with muscle spasms. 0:16
WOW! So informative and absolutely hilarious all at the same time :)
Jessica McDonald, bravo on yet another brilliant script! Hank - your comic timing is, as ever, perfect!
"... useful to the snakes because things their meals need to flee, like brains and muscles, don't work so well without blood..."
I've watched that line like 50 times and it just keeps getting funnier!!
Those blister beetles sound like tiny xenomorphs
I know the gila monsters venom undergoes a process to lower peoples blood sugar, but it got me thinking. Since the venom isn't that harmful to humans, do you think in a Macgyver type of emergency, you could get a gila monster to bite someone and potentially save their life? I'm not so medically inclined when it comes to these things, I'm just wondering if it would be possible?
Good question you might ask MacGyver because he was always able to come up with the answer to a problem when he needed to
"If you're fascinated by toxic stuff" just cling to any online discourse, comment section or webforum thread in general...
I still wonder how we came up with the idea of using venom as medicine. I mean, okay, it’s logical and everything, but still counterintuitive.
Shur'tugal Vodr Maybe it started as an observation. For example someone noticed that when he stepped on that nasty beetle, his nearby wart fell off
AtarahDerek Wow, interesting story! Thanks for the info!! 😄
I imagine that must have felt slightly disappointing for him
been around for a while. Some snake venoms prevent bruising, others prevent bleeding out. They're all different.
Great video, thank you.
Comment for the algorithm.
Love your stuff as always.
YOU MENTIONED GLIOMAS!!!! Yay. BUT WILL YOU PLEASE DO A VIDEO ON GLIOMAS??!?!! THANK YOU SCISHOW!!!
Great show keep it up bro aka Clifton Bass SR,😎
I think this video needs to trend on everything all over the world.
I love stuff like this -- finding *already existing* solutions to problems. Superb!
Thank you so much.
Oh wow, my uncle helped to develop Captopril
I love it that Hank has a shirt with molecules on it.
3:30 so why not it's used as Painkiller
Bc big pharma! Probably!?
I have always been interested in poisons and toxicology, although never terribly interested in death. The history of the synthesis of strychnine is fascinating. Well, you know, as far as organic chemistry can be.
Study of animal and plant venom is fascinating in drug research. Even if the venom itself is not useful, many times its method of action (or the way it works in the body) can lead to whole new classes of drugs that work in ways never even imaged a few years ago. At the same time we learn new things about how body does things like react to pain or cause neurological disorders, when we study how the venom's/toxins interact with the body.
An idea for a followup video: Toxic plants or plants that can harm animals/humans but are used for their medical potential. I think about substances like bromelain which is used in patients with burn injuries. Normally bromelain digests meat and flesh...
Perhaps Gila monsters have that compound to make their prey less energetic? With less sugar in the blood, they might become exhausted easily. Idk, just a random guess.
I use Botox for migraines, it's amazing. I haven't had one in a year.
I'm watching this in June 2022. It would be nice if we could have updates on some these substances that in 2018 were still unsure of
You learn in biology that nature is important because everything we get that helps us live will be influenced by nature in some way
If I was an educator, I think I would feel obligated to help my students get more stoked about STEM via your excellent videos! Keep up the great work!
12:10 that scorpion is pissed that it's saving people
That one about GLP1 was very useful. I’ve been struggling with being overweight for a while as well as higher than normal blood sugar. Since I need a prescription for glp1 drugs, I found berberine and I’m going to give that a try.
"Anything in
Small doses is medicine
Medium doses is food
And in large amount is poison"
Avecina, father of modern medicine
Love the intro!
The south American pit vipers he's talking about is the bothrops genus. Specifically the jerracasu and layacpris (im horrible ar spelling) but they are so medicinally significant right now. I believe it's the most saut after venom right now.
Venomology is amazing and helps save man kind from.
I still have a scar from a big, ugly blister I accidentally got from a blister beetle about 45 or so years ago as a kid. Best I could figure out, it got caught between my wrist and the ground, and didn't like it there. I didn't like the sensation I immediately got, either. Screamed my head off for a little bit, in fact, because it HURT!
Scientist, looking at a deadly poison: How can I milk you?
I honestly thought it was pronouced "Geela" Monster not "Heela" Monster.
The more you know...
It's based on the Spanish pronunciation of the letters. Just like George is pronounced "Horhay" in Spanish.
Don't take Hank as an authority on correct pronunciation. He, like many, many others, mispronounces "nuptial" as though the -tial part is pronounced like the -tual in "mutual", when it should be pronounced like the -tial in "martial".
nup-shul, not nup-shoo-al
That's okay, the important word is "monster".
Valuable information 💯💯💯🥊🎯🎯
but can we turn it back to poison?
asking for a friend...
Software Man we call that an overdose, but yeah, it's thus definitely possible
There are quite a number of potential poisons that are deadly enough and readily available to non-chemists.
Except for these bugs, pretty much all of these critters are dangerous to harvest. Plants on the other hand are pretty easy. Also engineering a food-poisoning by growing bacteria is not that difficult.
If you know a drug dealer grab a bunch of acid, it's hallucinogenic but a "safe" dose is in nanograms. Although it's illegal and I obviously don't have an experience with it.
Zach Waksmonski r u sure about that
"Sola dosis facit venenum," or "The dose makes the poison," is a founding principle of toxicology.
Everything... and I do mean EVERYTHING, as in every single substance in existence, yes even whatever thing you're thinking of to try to make a joke... is toxic in the right dose.
"All things are poison, and nothing is without poison; the dosage alone makes it so a thing is not a poison."
~ Paracelsus, born Theophrastus von Hohenheim
Botox is being used for stomach pain now too! Here in Tucson the north west hospital actually has a whole thing about it. I myself was treated with botox injection to stomach.
My pain went away! The only down side is you get resistant to botox and it doesnt continue to work as well. But they use it as a test for a procedure that can be done. If botox helped you, this procedure will help you.
Just got back from my surgery been healing 5 weeks. Another 3 and I should be back to normal. Stomach now the size of a tangerine.
Bee stings are said to aid in chronic pain with spinal issues and arthritis.
Just learned a heck of a lot in the last 12 minutes annnnnnd I'm a pharmacist. While I might have known about our old tried and true meds, the new research is fascinating! Maybe it's just so fascinating because of the presentation, I dunno.
This person is my favorite host on this chanel .
I have a pet DeathStalker scorpion! Fun facts!
Deathstalker Scorpion is the most metal-ass name I've ever heard.
*MY FAMILY MEMBERS ALWAYS THROW MENTAL TOXINS TO US.... AND IT WORKS*
Hopefully the tumor paint only comes in one colour.
I can think of an ex-girlfriend who'd spend weeks trying to decide which colour the surgeon should use.
Well not any shade of red,blue or yellow. All 3 are in the body.
Entertaining way to explain biochemicals
I wonder what percentage of fungi species have been investigated for possible medical use.
About time scorpions did something good.
PinkChucky15 I think Bear Grylls once said that he'd rather eat a scorpion than some vegetable he doesn't like (might've been asparagus?)
ElectricPyroclast Hmm, asparagus don’t sting though.
Scorpions are actually delicious and full of protein. They might sting, but that’s why you catch them carefully.
Fascinating stuff!
My boyfriend was on the expiratiantal test board!
The gilla monster diabetic medicine was AWESOME!!! HE ONLY had to do his treatment every 3 MONTHS! His blood sugar was like a normal person! No more insulin SHOTS for 2 yearz! Then tbe study was over!
(He even lost 35 lbs!)
My grandfather (ojiichan) used to catch and kill Mamushi (Japanese Pit Viper Gloydius blomhoffii,) and place them in a bottle then fill the bottle with Soju a Japanese distilled spirit. He'd let it age for about 6 months at room temp. I remember he had several bottles of this "Mamushi Sake" at various stages of aging. He'd drink a shot of the aged stuff every morning for medicinal purposes supposedly to keep him healthy. He was always very healthy so maybe it worked. On Okinawa they make a similar potion but they use their local venomous snake the Habu (Protobothrops flavoviridis also a Pit Viper). I've had this stuff, and I found it actually tasty.
Your grandpa is hardcore man...
As alcohol can denature proteins, I would argue that most likely any venom was deactivated. Maybe your grandpa was healthy because of good diet, regular exercise and good genes. Though drinking snake soaked sake sounds pretty bad ass.
What did he die from may I inquire?
Botox was the best thing I ever did for my face. Cost me a fortune because Medicare (Australia) doesn't cover it for tension type headaches - literal muscle spasms - but they do for prophylactic treatment for migraines. I don't understand their logic...
I don’t understand Pharmacare’s (Canada) logic either.
So I’m familiar with the host because of eons and I gotta say one thing this channel does better than Eons is adding text so people can read it
SciShow, this was a great episode. Some time in the future, would you be able to discuss toxicological synergy/ synergism? That is a very interesting topic, how some things in and of themselves are not so effective until you mix them with other chemicals.
"saved more people than it killed" sounds like Franz Haber lol. Look into that guy, it's pretty wild
Narrower, not smaller - right?
Regarding "tubes" (blood vessels)
Awesome video
Can’t they use properties of the last one to make anti-cancer drugs that only target cancerous cells and not healthy ones? That would be cool.
So you're saying we should eat venomous snakes raw?
Justin Y. you *could*
Venom isn't even toxic when ingested. Venom is toxic when injected. Poison is toxic when ingested.
#MuscleHankVsJustinY
As long as you avoid the venom glands you would be fine. People eat rattlesnake all the time after all.
Why are you everywhere