1114. Neurosarcoidosis and Rare Neuroimmune Disorders

In this "Ask the Expert" episode, Krissy Dilger of SRNA interviewed Dr. Giovanna Manzano about neurosarcoidosis and rare neuroimmune disorders. They explored the definition of neurosarcoidosis, its symptoms, and the diagnostic process, emphasizing the challenges in identifying the condition due to its diverse manifestations. Dr. Manzano delved into the potential causes of neurosarcoidosis, highlighting immune system dysregulation and the formation of granulomas. Treatment options, including steroids and immune suppressants, were discussed, and the chronic nature of the disease was explored, with considerations for relapses and long-term effects. The conversation concluded with insights into patient advocacy, the importance of early diagnosis, and ongoing research efforts in the field.
Giovanna S. Manzano, MD is a neuroimmunologist/MS specialist and neurohospitalist at the Massachusetts General Hospital and the Brigham and Women's Hospital in Boston, Massachusetts. She provides care to patients with neuroimmunologic diseases inclusive of CNS demyelinating disorders, autoimmune/paraneoplastic encephalitis and cerebellar degeneration, neurosarcoidosis, and neurotoxicities from oncologic therapies. Her research is focused on optimizing care delivery and approach to treatment of neuroimmunologic conditions by way of studies that emphasize patient reported outcomes, quality improvement, and clinical trial design.

[@anson.meadows]

CAR-T for Neuro Sarcoid?

[@wearesrna]

Hello, thank you for your question. Please email us at [e-mail] and we will try to provide you with resources to help answer your question.

[@jonneysings2938]

@@wearesrna This is literally my entire story just diagnosed last week. And everything the doctor mentioned. The euvitis the brain lesions with the inflation of the meningitis, all the boxes were checked off. I’m also in boston. Wondering if theirs more that can be done. Just started high dose prednisone myself. For me I was always getting sick but they never could quite pinpoint from what. It was like these viral infections I would get yearly that mimicked flu like symptoms. And the. Eventually causing the lymphadenopathy granulomas that I guess eventually turned itself into the neruro sarcoid today. I do hope more answers are found and that a cure is made.

[@wearesrna]

@@jonneysings2938 Hello, we're so sorry to hear about your diagnosis and symptoms. You may be able to find more information on our website at wearesrna.org/, and if you have questions, please email us at [e-mail], and we will try to direct you to resources that may help.